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The map label for this gene is bcd [H]

Identifier: 182678727

GI number: 182678727

Start: 1984824

End: 1986608

Strand: Reverse

Name: bcd [H]

Synonym: Bind_1754

Alternate gene names: 182678727

Gene position: 1986608-1984824 (Counterclockwise)

Preceding gene: 182678728

Following gene: 182678726

Centisome position: 47.64

GC content: 54.79

Gene sequence:

>1785_bases
ATGGCCAGCTACAAGGCTCCATTGCGCGATATGCGCTTTGTCATTTTCGAACTCATGGATTGCGGCGACATTACCACTTT
GCCTGGCTATGAGGAAGCAACGCCTGATCTCATCGATTCTGTTCTAGAGGAAGCGGCGCGCTTCTGCGAGCAAGTGCTTT
TCCCTCTGAATCGTTCTGGTGATGAGGAAGGATGCGTTTTTGATAGCGGCGTGGTGCGGACCCCAAAGGGGTTTCAGGAA
GCCTACAAGGCTTTCTGTGAAGCTGGTTGGCCAGGTATCACCTCTTCACCCGCTTATGGTGGGCAAGGGCTGCCCAAGAT
CGTGAATAGTCTGATCGAGGAAATGATCTGTTCCTCCAACCTCTCTTTCGGTCTTTACCCCGGCCTCAGCCATGGCGCCT
GTGTCGCCTTGGAGAGCCATGGTTCGGAAGAGCTCAAGGATAAATATCTGCCGAAACTTGTGGAAGGCACGTGGTCCGGC
ACGATGTGCTTGACCGAGCCCCATTGCGGCACTGATCTCGGCCTGTCCCGCACGAAGGCGGTGCCCGCGGAGGATGGCAC
TTACAGAATTACTGGTACCAAAATCTTCATCTCGGCCGGCGAACATGATTTAACGGAAAATATCCTTCATCTCGTCCTGG
CGCGCCTTCCCGATGCGCCTAAAGGGATTAAGGGCATCAGCCTTTTCCTCGTACCCAAATTTTTTGTTCATGATGACAAC
ACGCTTGGGGCACGTAACGGCGTCTCATGCGGCTCGATCGAACATAAGATGGGTATCAAAGCTTCAGCCACTTGCGTCAT
CAATTTCGATGAAGCAACGGGCTGGCTGGTCGGTGAGCCGCACAAGGGCATGCGTGCCATGTTCACGATGATGAACACGG
AACGCCTGGCTGTTGGTCTGCAAGGCCTTGGGATCGCCGAAGTTTCGTATCAGGGCGCTGTCGCTTATGCCCGTGAACGT
TTACAAGGCCGTTCCCTGACCGGGGCAAAATATCCCGATAAGCCGGCCGATCCCATCATCGTTCATCCCGATATTCGCCG
CATGTTGTTGACGCAGCGGGCTTATGCCGAAGGATGCCGTGCTTTCGGCATATGGGCGGCAAAGCATTTGGATCTCCGCA
ATCATCCTGATGCGACCGTGCGACAGGAAGCCGAAGAATTCGTCGCACTGGTGACGCCTGTCGTCAAAGCCTTGTTCACG
GATCTTGGCTCGGAAGCAGCCAATCTCGGTATGCAAGTGTTTGGCGGTCACGGCTACATTCGCGAGCATGGCATGGAGCA
ATATGCACGCGACGTCCGTATTGCCCAGATTTATGAAGGGACCAATGGCGTTCAGGCTCTTGATTTCGTCGGCCGCAAGC
TGCCCGCGGATATGGGGCGTTTGTTGCGCCGTTTCTTCCATCCCGTAGCCGCCTATATCGAGGAAAAATCTTCCGAAACG
ACACTGACGGAGTTTATCGATCCCCTCAATAAGGCGTTTACGCGCTTGCAACAGGCAACGATCAAGATTGCTCAAGCAGG
GCTACGCAATCCTGATGAAGCAGGCGCGGCCGCCACGGATTATCTCCGTTTATTTGGCCTCACAGCCTTGGCCTACCTTT
GGGCGCGTATGGCTGAAGTGAGCCTGCCGAAGATCGGTGCCGATGATACCGATGGATTTTACGTCGCCAAGGTCGGGACG
GCACGTTTCTTCATGCAGCGCCTGCTGCCGCAAACAGGTGCGCTGTTTTCTTCCATCATGGCTGGCAGCAAATCAACGAT
GGCTTTCGACGAGGCTGCGTTTTGA

Upstream 100 bases:

>100_bases
GGCAGCCCGGTACATTGGCGCGTATTGAACACATGCTGACGACTGGAAAGCCCTTACGGAATTAACAGGCGCATACAATA
ATTGTTCAGGAAAAAGCATC

Downstream 100 bases:

>100_bases
ACCCTGCCAGGGTCTGAAGGACGTATCATGAATCTTTGGTTCCGACTCCTCAATATCGTGCTCGGCAGCCTGGTACGGCG
TCGCCTGACGTTCGAAGAGC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MASYKAPLRDMRFVIFELMDCGDITTLPGYEEATPDLIDSVLEEAARFCEQVLFPLNRSGDEEGCVFDSGVVRTPKGFQE
AYKAFCEAGWPGITSSPAYGGQGLPKIVNSLIEEMICSSNLSFGLYPGLSHGACVALESHGSEELKDKYLPKLVEGTWSG
TMCLTEPHCGTDLGLSRTKAVPAEDGTYRITGTKIFISAGEHDLTENILHLVLARLPDAPKGIKGISLFLVPKFFVHDDN
TLGARNGVSCGSIEHKMGIKASATCVINFDEATGWLVGEPHKGMRAMFTMMNTERLAVGLQGLGIAEVSYQGAVAYARER
LQGRSLTGAKYPDKPADPIIVHPDIRRMLLTQRAYAEGCRAFGIWAAKHLDLRNHPDATVRQEAEEFVALVTPVVKALFT
DLGSEAANLGMQVFGGHGYIREHGMEQYARDVRIAQIYEGTNGVQALDFVGRKLPADMGRLLRRFFHPVAAYIEEKSSET
TLTEFIDPLNKAFTRLQQATIKIAQAGLRNPDEAGAAATDYLRLFGLTALAYLWARMAEVSLPKIGADDTDGFYVAKVGT
ARFFMQRLLPQTGALFSSIMAGSKSTMAFDEAAF

Sequences:

>Translated_594_residues
MASYKAPLRDMRFVIFELMDCGDITTLPGYEEATPDLIDSVLEEAARFCEQVLFPLNRSGDEEGCVFDSGVVRTPKGFQE
AYKAFCEAGWPGITSSPAYGGQGLPKIVNSLIEEMICSSNLSFGLYPGLSHGACVALESHGSEELKDKYLPKLVEGTWSG
TMCLTEPHCGTDLGLSRTKAVPAEDGTYRITGTKIFISAGEHDLTENILHLVLARLPDAPKGIKGISLFLVPKFFVHDDN
TLGARNGVSCGSIEHKMGIKASATCVINFDEATGWLVGEPHKGMRAMFTMMNTERLAVGLQGLGIAEVSYQGAVAYARER
LQGRSLTGAKYPDKPADPIIVHPDIRRMLLTQRAYAEGCRAFGIWAAKHLDLRNHPDATVRQEAEEFVALVTPVVKALFT
DLGSEAANLGMQVFGGHGYIREHGMEQYARDVRIAQIYEGTNGVQALDFVGRKLPADMGRLLRRFFHPVAAYIEEKSSET
TLTEFIDPLNKAFTRLQQATIKIAQAGLRNPDEAGAAATDYLRLFGLTALAYLWARMAEVSLPKIGADDTDGFYVAKVGT
ARFFMQRLLPQTGALFSSIMAGSKSTMAFDEAAF
>Mature_593_residues
ASYKAPLRDMRFVIFELMDCGDITTLPGYEEATPDLIDSVLEEAARFCEQVLFPLNRSGDEEGCVFDSGVVRTPKGFQEA
YKAFCEAGWPGITSSPAYGGQGLPKIVNSLIEEMICSSNLSFGLYPGLSHGACVALESHGSEELKDKYLPKLVEGTWSGT
MCLTEPHCGTDLGLSRTKAVPAEDGTYRITGTKIFISAGEHDLTENILHLVLARLPDAPKGIKGISLFLVPKFFVHDDNT
LGARNGVSCGSIEHKMGIKASATCVINFDEATGWLVGEPHKGMRAMFTMMNTERLAVGLQGLGIAEVSYQGAVAYARERL
QGRSLTGAKYPDKPADPIIVHPDIRRMLLTQRAYAEGCRAFGIWAAKHLDLRNHPDATVRQEAEEFVALVTPVVKALFTD
LGSEAANLGMQVFGGHGYIREHGMEQYARDVRIAQIYEGTNGVQALDFVGRKLPADMGRLLRRFFHPVAAYIEEKSSETT
LTEFIDPLNKAFTRLQQATIKIAQAGLRNPDEAGAAATDYLRLFGLTALAYLWARMAEVSLPKIGADDTDGFYVAKVGTA
RFFMQRLLPQTGALFSSIMAGSKSTMAFDEAAF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=416, Percent_Identity=24.5192307692308, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI4557235, Length=440, Percent_Identity=28.1818181818182, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI76496475, Length=440, Percent_Identity=28.1818181818182, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI21361497, Length=396, Percent_Identity=25.2525252525253, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI4557233, Length=426, Percent_Identity=26.2910798122066, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI226958412, Length=393, Percent_Identity=26.972010178117, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI226958414, Length=390, Percent_Identity=26.9230769230769, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI7656849, Length=372, Percent_Identity=26.8817204301075, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI4501857, Length=387, Percent_Identity=25.3229974160207, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI187960098, Length=313, Percent_Identity=27.1565495207668, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4557231, Length=313, Percent_Identity=27.1565495207668, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI87082384, Length=482, Percent_Identity=25.3112033195021, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17533517, Length=421, Percent_Identity=26.8408551068884, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17508101, Length=412, Percent_Identity=27.9126213592233, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17534899, Length=362, Percent_Identity=29.0055248618785, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=366, Percent_Identity=25.1366120218579, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17569725, Length=413, Percent_Identity=26.8765133171913, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71985184, Length=371, Percent_Identity=26.4150943396226, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=25.9259259259259, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI86563383, Length=361, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI86563381, Length=361, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=241, Percent_Identity=31.1203319502075, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI32563615, Length=236, Percent_Identity=27.1186440677966, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551932, Length=381, Percent_Identity=23.8845144356955, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=251, Percent_Identity=28.6852589641434, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=287, Percent_Identity=27.1777003484321, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21356377, Length=363, Percent_Identity=28.099173553719, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281363737, Length=401, Percent_Identity=25.6857855361596, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24666513, Length=408, Percent_Identity=26.7156862745098, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=25, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21355753, Length=421, Percent_Identity=24.4655581947743, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24660351, Length=313, Percent_Identity=28.1150159744409, Blast_Score=84, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 64801; Mature: 64670

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASYKAPLRDMRFVIFELMDCGDITTLPGYEEATPDLIDSVLEEAARFCEQVLFPLNRSG
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
DEEGCVFDSGVVRTPKGFQEAYKAFCEAGWPGITSSPAYGGQGLPKIVNSLIEEMICSSN
CCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
LSFGLYPGLSHGACVALESHGSEELKDKYLPKLVEGTWSGTMCLTEPHCGTDLGLSRTKA
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCC
VPAEDGTYRITGTKIFISAGEHDLTENILHLVLARLPDAPKGIKGISLFLVPKFFVHDDN
CCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEECCC
TLGARNGVSCGSIEHKMGIKASATCVINFDEATGWLVGEPHKGMRAMFTMMNTERLAVGL
CCCCCCCCCCCCCHHHCCCCEEEEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHHH
QGLGIAEVSYQGAVAYARERLQGRSLTGAKYPDKPADPIIVHPDIRRMLLTQRAYAEGCR
CCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHH
AFGIWAAKHLDLRNHPDATVRQEAEEFVALVTPVVKALFTDLGSEAANLGMQVFGGHGYI
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEECCCCHH
REHGMEQYARDVRIAQIYEGTNGVQALDFVGRKLPADMGRLLRRFFHPVAAYIEEKSSET
HHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCH
TLTEFIDPLNKAFTRLQQATIKIAQAGLRNPDEAGAAATDYLRLFGLTALAYLWARMAEV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
SLPKIGADDTDGFYVAKVGTARFFMQRLLPQTGALFSSIMAGSKSTMAFDEAAF
CCCCCCCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHCCC
>Mature Secondary Structure 
ASYKAPLRDMRFVIFELMDCGDITTLPGYEEATPDLIDSVLEEAARFCEQVLFPLNRSG
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
DEEGCVFDSGVVRTPKGFQEAYKAFCEAGWPGITSSPAYGGQGLPKIVNSLIEEMICSSN
CCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
LSFGLYPGLSHGACVALESHGSEELKDKYLPKLVEGTWSGTMCLTEPHCGTDLGLSRTKA
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCC
VPAEDGTYRITGTKIFISAGEHDLTENILHLVLARLPDAPKGIKGISLFLVPKFFVHDDN
CCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEECCC
TLGARNGVSCGSIEHKMGIKASATCVINFDEATGWLVGEPHKGMRAMFTMMNTERLAVGL
CCCCCCCCCCCCCHHHCCCCEEEEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHHH
QGLGIAEVSYQGAVAYARERLQGRSLTGAKYPDKPADPIIVHPDIRRMLLTQRAYAEGCR
CCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHH
AFGIWAAKHLDLRNHPDATVRQEAEEFVALVTPVVKALFTDLGSEAANLGMQVFGGHGYI
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEECCCCHH
REHGMEQYARDVRIAQIYEGTNGVQALDFVGRKLPADMGRLLRRFFHPVAAYIEEKSSET
HHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCH
TLTEFIDPLNKAFTRLQQATIKIAQAGLRNPDEAGAAATDYLRLFGLTALAYLWARMAEV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
SLPKIGADDTDGFYVAKVGTARFFMQRLLPQTGALFSSIMAGSKSTMAFDEAAF
CCCCCCCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]