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The map label for this gene is fecR [H]

Identifier: 17547638

GI number: 17547638

Start: 3145917

End: 3146741

Strand: Direct

Name: fecR [H]

Synonym: RSc2919

Alternate gene names: 17547638

Gene position: 3145917-3146741 (Clockwise)

Preceding gene: 17547637

Following gene: 17547639

Centisome position: 84.65

GC content: 73.21

Gene sequence:

>825_bases
ATGTCCCACACCCCCGAAGAATTCGCCCGCGAGGAAGCCAGCCTGGCACGCCACCGTGCCGCGCTGCGACAGCGCTTCGC
CTTGCCGCCGGCGCCCGCTCGTGCGCCGCGCCGCCGCGGGCCGCTCATCGTGGCCGGCATTGCCGCCATGTTCGGTGCGT
TGCTGTGGGCCGATCCGGCATTCCACTCACAGCGATACGCCACCGCGGCCGGCGCGCGCCAGCAGATCAGCCTGTCCGAC
GGCACCTCGGTCACGCTCAACACCCGCACCGTGGCCGAGGTGGAATGGCATCTGCGCTCGCGGCAGGTGCGGCTGGTCGA
TGGCGAGGCGCTCTTCGACGTGGCCCAGGCGTCACGGCCGTTCATCGTGCGGGCCGGCGGCACGACGGTGCGCGTGATGG
GCACGGCGTTCAACGTGCACCGGGCGGATCCGCGCATTACCGTGACGGTCCTGCGCGGCCGCGTGCACGTGGAAGACGCC
TCGGGCGATGCCGTGCTGCTGGGCCCGCGCCAAGCCGCCGACACCGGCGCCGGCACACTCAACGCGCGCGCCGAGCCCGA
CCCCGCCGCGGCCGTGGCCTGGAAGGACGGCAAGCTGCTGTTCGATCACACGCCGCTTGCGCAGGCCGTGGCCGACATCA
ACCGCTACCGCGCCGCGCCGGTCACGCTGGCCGATCCCGCGCTGGGGCGCCTGCAGATTTCCGGCGTCTTCGACAGCACG
CGCACCGACGCGCTGCTCGATCTGCTGCCCTCCGTCCTGCCGGTGACGATCCGGCGCGAGGCGGACGACGCCATCCACGT
GCTGGCCCGCGGCGCATCGCGCTGA

Upstream 100 bases:

>100_bases
CGGTAAGATTGGGGATTTCGCGCAAGGCGGTGGAGAAGCACATCCGGCGGGGCATGACAGCCTGCCGCGCCGCGCTGGAC
CGCCCCGAACCGCGTTGAGC

Downstream 100 bases:

>100_bases
CCACCGGCGCCGCCGAGGTAGGGGTGCGCGGCGCCCCGCCCGTCTACTTCCCTGTGACCTAGACCAACAAACGGGGAGCC
TTCACAGTGAATCGACATCG

Product: IRON transport-sensory transduction transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSHTPEEFAREEASLARHRAALRQRFALPPAPARAPRRRGPLIVAGIAAMFGALLWADPAFHSQRYATAAGARQQISLSD
GTSVTLNTRTVAEVEWHLRSRQVRLVDGEALFDVAQASRPFIVRAGGTTVRVMGTAFNVHRADPRITVTVLRGRVHVEDA
SGDAVLLGPRQAADTGAGTLNARAEPDPAAAVAWKDGKLLFDHTPLAQAVADINRYRAAPVTLADPALGRLQISGVFDST
RTDALLDLLPSVLPVTIRREADDAIHVLARGASR

Sequences:

>Translated_274_residues
MSHTPEEFAREEASLARHRAALRQRFALPPAPARAPRRRGPLIVAGIAAMFGALLWADPAFHSQRYATAAGARQQISLSD
GTSVTLNTRTVAEVEWHLRSRQVRLVDGEALFDVAQASRPFIVRAGGTTVRVMGTAFNVHRADPRITVTVLRGRVHVEDA
SGDAVLLGPRQAADTGAGTLNARAEPDPAAAVAWKDGKLLFDHTPLAQAVADINRYRAAPVTLADPALGRLQISGVFDST
RTDALLDLLPSVLPVTIRREADDAIHVLARGASR
>Mature_273_residues
SHTPEEFAREEASLARHRAALRQRFALPPAPARAPRRRGPLIVAGIAAMFGALLWADPAFHSQRYATAAGARQQISLSDG
TSVTLNTRTVAEVEWHLRSRQVRLVDGEALFDVAQASRPFIVRAGGTTVRVMGTAFNVHRADPRITVTVLRGRVHVEDAS
GDAVLLGPRQAADTGAGTLNARAEPDPAAAVAWKDGKLLFDHTPLAQAVADINRYRAAPVTLADPALGRLQISGVFDSTR
TDALLDLLPSVLPVTIRREADDAIHVLARGASR

Specific function: Regulation of iron dicitrate transport. In the absence of citrate fecR inactivates fecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm [H]

COG id: COG3712

COG function: function code PT; Fe2+-dicitrate sensor, membrane component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790745, Length=197, Percent_Identity=31.9796954314721, Blast_Score=81, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006860
- InterPro:   IPR012373 [H]

Pfam domain/function: PF04773 FecR [H]

EC number: NA

Molecular weight: Translated: 29412; Mature: 29281

Theoretical pI: Translated: 11.24; Mature: 11.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHTPEEFAREEASLARHRAALRQRFALPPAPARAPRRRGPLIVAGIAAMFGALLWADPA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCC
FHSQRYATAAGARQQISLSDGTSVTLNTRTVAEVEWHLRSRQVRLVDGEALFDVAQASRP
CCCCHHHHHCCCCEEEEECCCCEEEEECCEEEEEHEECCCCEEEEECCHHHHHHHHCCCC
FIVRAGGTTVRVMGTAFNVHRADPRITVTVLRGRVHVEDASGDAVLLGPRQAADTGAGTL
EEEEECCCEEEEEEEEEEEECCCCCEEEEEEECEEEEEECCCCEEEECCCCCCCCCCCCC
NARAEPDPAAAVAWKDGKLLFDHTPLAQAVADINRYRAAPVTLADPALGRLQISGVFDST
CCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHCCCCEEECCCCCCEEEEEEECCCC
RTDALLDLLPSVLPVTIRREADDAIHVLARGASR
HHHHHHHHHHHHHCEEEECCCCHHHHHHHCCCCC
>Mature Secondary Structure 
SHTPEEFAREEASLARHRAALRQRFALPPAPARAPRRRGPLIVAGIAAMFGALLWADPA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCC
FHSQRYATAAGARQQISLSDGTSVTLNTRTVAEVEWHLRSRQVRLVDGEALFDVAQASRP
CCCCHHHHHCCCCEEEEECCCCEEEEECCEEEEEHEECCCCEEEEECCHHHHHHHHCCCC
FIVRAGGTTVRVMGTAFNVHRADPRITVTVLRGRVHVEDASGDAVLLGPRQAADTGAGTL
EEEEECCCEEEEEEEEEEEECCCCCEEEEEEECEEEEEECCCCEEEECCCCCCCCCCCCC
NARAEPDPAAAVAWKDGKLLFDHTPLAQAVADINRYRAAPVTLADPALGRLQISGVFDST
CCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHCCCCEEECCCCCCEEEEEEECCCC
RTDALLDLLPSVLPVTIRREADDAIHVLARGASR
HHHHHHHHHHHHHCEEEECCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2254251; 7610040; 9278503 [H]