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The map label for this gene is cyoB1 [H]

Identifier: 17547635

GI number: 17547635

Start: 3141803

End: 3143782

Strand: Reverse

Name: cyoB1 [H]

Synonym: RSc2916

Alternate gene names: 17547635

Gene position: 3143782-3141803 (Counterclockwise)

Preceding gene: 17547636

Following gene: 17547634

Centisome position: 84.59

GC content: 63.13

Gene sequence:

>1980_bases
ATGTTTGGCAAGTTGAGTCTGGAGGCCATTCCGCTGCACGAGCCCATCGTGGTCGTGACAGTGTCGGCCATTCTGCTGGG
TGGCGCCGGCCTGTTTGGCCTGATCACCTACTTCAAGAAGTGGTCGTACCTTTGGAATGAGTGGATCACCTCGGTCGACC
ACAAGAAGATCGGCGTGATGTATTGCATTCTGGCGATCGTGATGCTGCTGCGCGGCTTTGCCGACGCCATCATGATGCGC
TCGCAACTGGCGCTCGCCTCGGGTGGTGGTGCCGGCTATCTGCCGCCCGAGCACTACGACCAGATCTTCACCGCGCACGG
CGTGATCATGATCTTCTTCATGGCCATGCCGCTGATGACGGGCCTGATCAACCTGATCGTGCCGCTGCAGATCGGCGCGC
GCGACGTGGCCTTCCCGTTCCTGAACACGCTGTCGTTCTGGCTGGCGGCCGCGGGCGTGGTGCTGGTCAACCTGTCGCTG
GGCGTCGGCAACTTCGCGCGCACCGGCTGGCTGGCCTACCCGCCGCTGTCGGAGCTGGCCTACAGCCCCGACGTGGGGGT
CGACTACTACATCTGGGCGCTGCAGATATCCGGGTTGGGCACCTTGCTGACCGGGGTGAACTTCGTCGCGACCATCTTCA
AGATGCGCGCGCCGGGCATGACGCTGATGCGCATGCCGATCTTCACCTGGACGGCCCTGTGCGCCAACATCCTGATCGTG
GCGGCCTTTCCGGTGCTGACCGTGGCGCTGGCGCTGCTGGGCCTGGACCGCTACCTGGACATGCACTTCTTCACGAACAC
GGCCGGCGGCAACGCCATGCTGTATGTGAACCTGATCTGGATCTGGGGCCACCCCGAGGTGTACATCCTGGTTCTGCCGG
CATTCGGCATGTTCTCGGAAATCATCTCGACGTTCTCGCGCAAGAAGCTGTTCGGCTACACGTCGATGGTGTACGCGACG
GCGGGCATCACGGTGCTGTCGTTCCTGGTGTGGCTGCACCACTTCTTCACCATGGGCTCGGGCGCGAACGTCAACGCGTT
CTTCGGCATCGCCACCATGATCATCTCCATCCCGACCGGGGTGAAGATCTTCAACTGGCTGTTCACGATGTACCGCGGCC
GCGTCGAGTTCACCTCGCCGGTGCTGTGGACGATCGGCTTCATGATCACCTTCGTGATCGGCGGGATGACCGGTGTGCTG
CTGGCGGTGCCGGGCGCCGACTTCCTGCTGCACAACAGCCTGTTCCTGATCGCCCACTTCCATAACACCATCATCGGTGG
CGTGGTGTTCGGCTACCTGGCGGGCATCACCTTCTGGTTCCCGAAGGCCTTCGGCTTCAAGCTGGACGAGAAGTGGGGCA
AGCGCGCCTTCTGGTGCTGGTTCGTCGGCTTCTACCTGGCCTTCATGCCGCTGTACGTGCTGGGCTTCATGGGCATGACG
CGCCGCCTGAACCATACCGACAACCCGGCTTGGCAGCCGTGGCTGATCGTCGCCGTGATCGGCGCCGCGGTCATCGCCTG
CGGTATCGCTTCGCAGCTCATCCAGATCGTCGTCAGCATCCGCAACCGCAAGGCACTGGCCGACGTGACCGGCGACCCGT
GGGGCGGCCGCACGCTGGAGTGGGCCACGTCGTCGCCGCCGGCGCACTACAACTTCGCGACCGTGCCGGTGGTGCGTGAC
ATCGACGCCTTCGCCGACATGAAGGCGCGCGGCGAGGTGCCGACGCAGGTCGCCGCCAGCTACGAGAAGATCCACATGCC
GAAGAACACCGGCGCCGGCTTCTTCATCGGCATGTTCTCGATCGTGATGGGCTTCGCCCTGGTGTGGCACATCTGGTGGA
TGGCCGTGCTGGGTCTGGGCGGCATGATCGTCAGCTTCATCTTCCGCAGCAACAACGACGACATCGATTACTACGTGCCC
GCTCAAGAGGTTCATGAGACCGAGTCGGCCTACTTCCAACGCATCGGTTCGCAGGCTTAA

Upstream 100 bases:

>100_bases
CACGGCCGAGGCGGCAACGCGTCCGCTGCCGGTGCAGTCCGCCCTGCCGGCGCCGAAGGCTGCAACGGCGGCCACGCCCA
AGAATTCCTAGGAGTTGACG

Downstream 100 bases:

>100_bases
ACCATGGCTACCAATGTTCTAGACGGCCACGCCGCGCACGCCGCGGACCACGGCCACGCGCATGACCATGCGCACCACCA
CGATGCCGCAGACACCAAGG

Product: transmembrane cytochrome O ubiquinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 659; Mature: 659

Protein sequence:

>659_residues
MFGKLSLEAIPLHEPIVVVTVSAILLGGAGLFGLITYFKKWSYLWNEWITSVDHKKIGVMYCILAIVMLLRGFADAIMMR
SQLALASGGGAGYLPPEHYDQIFTAHGVIMIFFMAMPLMTGLINLIVPLQIGARDVAFPFLNTLSFWLAAAGVVLVNLSL
GVGNFARTGWLAYPPLSELAYSPDVGVDYYIWALQISGLGTLLTGVNFVATIFKMRAPGMTLMRMPIFTWTALCANILIV
AAFPVLTVALALLGLDRYLDMHFFTNTAGGNAMLYVNLIWIWGHPEVYILVLPAFGMFSEIISTFSRKKLFGYTSMVYAT
AGITVLSFLVWLHHFFTMGSGANVNAFFGIATMIISIPTGVKIFNWLFTMYRGRVEFTSPVLWTIGFMITFVIGGMTGVL
LAVPGADFLLHNSLFLIAHFHNTIIGGVVFGYLAGITFWFPKAFGFKLDEKWGKRAFWCWFVGFYLAFMPLYVLGFMGMT
RRLNHTDNPAWQPWLIVAVIGAAVIACGIASQLIQIVVSIRNRKALADVTGDPWGGRTLEWATSSPPAHYNFATVPVVRD
IDAFADMKARGEVPTQVAASYEKIHMPKNTGAGFFIGMFSIVMGFALVWHIWWMAVLGLGGMIVSFIFRSNNDDIDYYVP
AQEVHETESAYFQRIGSQA

Sequences:

>Translated_659_residues
MFGKLSLEAIPLHEPIVVVTVSAILLGGAGLFGLITYFKKWSYLWNEWITSVDHKKIGVMYCILAIVMLLRGFADAIMMR
SQLALASGGGAGYLPPEHYDQIFTAHGVIMIFFMAMPLMTGLINLIVPLQIGARDVAFPFLNTLSFWLAAAGVVLVNLSL
GVGNFARTGWLAYPPLSELAYSPDVGVDYYIWALQISGLGTLLTGVNFVATIFKMRAPGMTLMRMPIFTWTALCANILIV
AAFPVLTVALALLGLDRYLDMHFFTNTAGGNAMLYVNLIWIWGHPEVYILVLPAFGMFSEIISTFSRKKLFGYTSMVYAT
AGITVLSFLVWLHHFFTMGSGANVNAFFGIATMIISIPTGVKIFNWLFTMYRGRVEFTSPVLWTIGFMITFVIGGMTGVL
LAVPGADFLLHNSLFLIAHFHNTIIGGVVFGYLAGITFWFPKAFGFKLDEKWGKRAFWCWFVGFYLAFMPLYVLGFMGMT
RRLNHTDNPAWQPWLIVAVIGAAVIACGIASQLIQIVVSIRNRKALADVTGDPWGGRTLEWATSSPPAHYNFATVPVVRD
IDAFADMKARGEVPTQVAASYEKIHMPKNTGAGFFIGMFSIVMGFALVWHIWWMAVLGLGGMIVSFIFRSNNDDIDYYVP
AQEVHETESAYFQRIGSQA
>Mature_659_residues
MFGKLSLEAIPLHEPIVVVTVSAILLGGAGLFGLITYFKKWSYLWNEWITSVDHKKIGVMYCILAIVMLLRGFADAIMMR
SQLALASGGGAGYLPPEHYDQIFTAHGVIMIFFMAMPLMTGLINLIVPLQIGARDVAFPFLNTLSFWLAAAGVVLVNLSL
GVGNFARTGWLAYPPLSELAYSPDVGVDYYIWALQISGLGTLLTGVNFVATIFKMRAPGMTLMRMPIFTWTALCANILIV
AAFPVLTVALALLGLDRYLDMHFFTNTAGGNAMLYVNLIWIWGHPEVYILVLPAFGMFSEIISTFSRKKLFGYTSMVYAT
AGITVLSFLVWLHHFFTMGSGANVNAFFGIATMIISIPTGVKIFNWLFTMYRGRVEFTSPVLWTIGFMITFVIGGMTGVL
LAVPGADFLLHNSLFLIAHFHNTIIGGVVFGYLAGITFWFPKAFGFKLDEKWGKRAFWCWFVGFYLAFMPLYVLGFMGMT
RRLNHTDNPAWQPWLIVAVIGAAVIACGIASQLIQIVVSIRNRKALADVTGDPWGGRTLEWATSSPPAHYNFATVPVVRD
IDAFADMKARGEVPTQVAASYEKIHMPKNTGAGFFIGMFSIVMGFALVWHIWWMAVLGLGGMIVSFIFRSNNDDIDYYVP
AQEVHETESAYFQRIGSQA

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=511, Percent_Identity=38.5518590998043, Blast_Score=338, Evalue=7e-93,
Organism=Escherichia coli, GI1786634, Length=655, Percent_Identity=69.9236641221374, Blast_Score=968, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=536, Percent_Identity=36.9402985074627, Blast_Score=340, Evalue=5e-94,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=42.1052631578947, Blast_Score=248, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6226523, Length=248, Percent_Identity=35.0806451612903, Blast_Score=132, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 72945; Mature: 72945

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGKLSLEAIPLHEPIVVVTVSAILLGGAGLFGLITYFKKWSYLWNEWITSVDHKKIGVM
CCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YCILAIVMLLRGFADAIMMRSQLALASGGGAGYLPPEHYDQIFTAHGVIMIFFMAMPLMT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLINLIVPLQIGARDVAFPFLNTLSFWLAAAGVVLVNLSLGVGNFARTGWLAYPPLSELA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHCCCCCCCCHHHHC
YSPDVGVDYYIWALQISGLGTLLTGVNFVATIFKMRAPGMTLMRMPIFTWTALCANILIV
CCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AAFPVLTVALALLGLDRYLDMHFFTNTAGGNAMLYVNLIWIWGHPEVYILVLPAFGMFSE
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEEEEECCCCEEEEEECCHHHHHH
IISTFSRKKLFGYTSMVYATAGITVLSFLVWLHHFFTMGSGANVNAFFGIATMIISIPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
VKIFNWLFTMYRGRVEFTSPVLWTIGFMITFVIGGMTGVLLAVPGADFLLHNSLFLIAHF
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCEEEEEHH
HNTIIGGVVFGYLAGITFWFPKAFGFKLDEKWGKRAFWCWFVGFYLAFMPLYVLGFMGMT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLNHTDNPAWQPWLIVAVIGAAVIACGIASQLIQIVVSIRNRKALADVTGDPWGGRTLE
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCEEE
WATSSPPAHYNFATVPVVRDIDAFADMKARGEVPTQVAASYEKIHMPKNTGAGFFIGMFS
ECCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
IVMGFALVWHIWWMAVLGLGGMIVSFIFRSNNDDIDYYVPAQEVHETESAYFQRIGSQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFGKLSLEAIPLHEPIVVVTVSAILLGGAGLFGLITYFKKWSYLWNEWITSVDHKKIGVM
CCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YCILAIVMLLRGFADAIMMRSQLALASGGGAGYLPPEHYDQIFTAHGVIMIFFMAMPLMT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLINLIVPLQIGARDVAFPFLNTLSFWLAAAGVVLVNLSLGVGNFARTGWLAYPPLSELA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHCCCCCCCCHHHHC
YSPDVGVDYYIWALQISGLGTLLTGVNFVATIFKMRAPGMTLMRMPIFTWTALCANILIV
CCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AAFPVLTVALALLGLDRYLDMHFFTNTAGGNAMLYVNLIWIWGHPEVYILVLPAFGMFSE
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEEEEECCCCEEEEEECCHHHHHH
IISTFSRKKLFGYTSMVYATAGITVLSFLVWLHHFFTMGSGANVNAFFGIATMIISIPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
VKIFNWLFTMYRGRVEFTSPVLWTIGFMITFVIGGMTGVLLAVPGADFLLHNSLFLIAHF
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCEEEEEHH
HNTIIGGVVFGYLAGITFWFPKAFGFKLDEKWGKRAFWCWFVGFYLAFMPLYVLGFMGMT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLNHTDNPAWQPWLIVAVIGAAVIACGIASQLIQIVVSIRNRKALADVTGDPWGGRTLE
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCEEE
WATSSPPAHYNFATVPVVRDIDAFADMKARGEVPTQVAASYEKIHMPKNTGAGFFIGMFS
ECCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
IVMGFALVWHIWWMAVLGLGGMIVSFIFRSNNDDIDYYVPAQEVHETESAYFQRIGSQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]