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The map label for this gene is murG

Identifier: 17547563

GI number: 17547563

Start: 3059398

End: 3060495

Strand: Reverse

Name: murG

Synonym: RSc2844

Alternate gene names: 17547563

Gene position: 3060495-3059398 (Counterclockwise)

Preceding gene: 17547564

Following gene: 17547562

Centisome position: 82.35

GC content: 72.4

Gene sequence:

>1098_bases
ATGACGGCACGCGTGTCGGCCGATCTGCCGCGCACCCTCCTCGTCATGGCCGGCGGCACCGGCGGCCACATCTTCCCCGC
GCTGTCGGTGGCCAGGCTGCTGGCCGCGCGCGGGTGGCAGGTGGTGTGGCTCGGCAACGCGAGCGGCATGGAAGGCCAGC
TCGTGCCCAAGCACGGTTTCCCGCTGGAGTCGGTGCGTTTTGGCGGTGTGCGCGGCAAGGGCCTCGTCACCAAGTTCCTG
CTGCCGCTGAACCTGCTGCGCGCGTTCTGGCAGAGCCTGGGCGTGGTGCGCCGCGTGCGTCCGAACGTGGTGCTGGGCAT
GGGCGGCTACATCACCTTTCCGGGCGGCATGATGAGCGTGCTGCTGGGCGCGCCGCTGGTGCTGCACGAACAGAATTCGA
TCGCGGGCCTGGCCAATCGCGTGCTCGCGCGCGTGGCCGATCGCGTGCTGTGCGCCTTTCCGGGTGCGCTGCCCGGCGCC
GAGTGGGTCGGCAATCCGATCCGTGCCGATCTGGCGGCGCTGCCGTCGCCGCAGGCGCGCTATGCCGAGCGGAGCGGTCC
GCTGCGGGTGCTGGTCGTGGGGGGCAGCCTGGGCGCCGCCGCGCTCAATGACGTGGTGCCCCGGGCGCTGGCCCTGCTGC
CCGCCGACACGCGCCCGATCGTCATCCACCAGGCCGGCGCCAAGCAGATCGACACGCTGCGCGCCAACTACGCCGCCGTG
GGCATCGACGAGACGCACGCGCAGGCCGTGCCCTTCATCGACGACATGGCCGCTGCCTATGCGCAGGCGGATCTGGTGAT
CTGCCGCGCCGGCGCGATGACGGTGTCGGAGGTGGCCGCGGCCGGGGTGGCGGCGCTGTTCGTGCCGTTCCCGCATGCGG
TGGACGACCACCAGACCACCAACGCGCGCTTCCTGTCCGAGCGCGGCGCGGCGCTGCTGGTGCCCCAGCCGTCGCTGGGG
CCGGCATCGCTGGCGGATACACTCGCGTCCCTGACGCGCGCGCAATTGGCCGATATGGCGGCCAAAGCACGCGAGCAGGC
GCGGCCGGAAGCGGCCGAGCGTGTCGCCGACATCTGTGTCGCGGCGGCAAGGGCATAG

Upstream 100 bases:

>100_bases
TCAGCTACGGCGGTTCGGGCATCCTGATGAACTGCATGGCGATCGCGCTGCTGCTCCGTATCGACTACGAGAACCGCGTC
CTGATGCGTGGAGGGAAGGT

Downstream 100 bases:

>100_bases
GGAACCGATTTATGAAGCACATCGTCAAGAACATCCATTTCGTGGGCATCGGCGGCGCCGGCATGAGCGGCATCGCCGAG
GTGCTGCTGAACCTGGGCTA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTARVSADLPRTLLVMAGGTGGHIFPALSVARLLAARGWQVVWLGNASGMEGQLVPKHGFPLESVRFGGVRGKGLVTKFL
LPLNLLRAFWQSLGVVRRVRPNVVLGMGGYITFPGGMMSVLLGAPLVLHEQNSIAGLANRVLARVADRVLCAFPGALPGA
EWVGNPIRADLAALPSPQARYAERSGPLRVLVVGGSLGAAALNDVVPRALALLPADTRPIVIHQAGAKQIDTLRANYAAV
GIDETHAQAVPFIDDMAAAYAQADLVICRAGAMTVSEVAAAGVAALFVPFPHAVDDHQTTNARFLSERGAALLVPQPSLG
PASLADTLASLTRAQLADMAAKAREQARPEAAERVADICVAAARA

Sequences:

>Translated_365_residues
MTARVSADLPRTLLVMAGGTGGHIFPALSVARLLAARGWQVVWLGNASGMEGQLVPKHGFPLESVRFGGVRGKGLVTKFL
LPLNLLRAFWQSLGVVRRVRPNVVLGMGGYITFPGGMMSVLLGAPLVLHEQNSIAGLANRVLARVADRVLCAFPGALPGA
EWVGNPIRADLAALPSPQARYAERSGPLRVLVVGGSLGAAALNDVVPRALALLPADTRPIVIHQAGAKQIDTLRANYAAV
GIDETHAQAVPFIDDMAAAYAQADLVICRAGAMTVSEVAAAGVAALFVPFPHAVDDHQTTNARFLSERGAALLVPQPSLG
PASLADTLASLTRAQLADMAAKAREQARPEAAERVADICVAAARA
>Mature_364_residues
TARVSADLPRTLLVMAGGTGGHIFPALSVARLLAARGWQVVWLGNASGMEGQLVPKHGFPLESVRFGGVRGKGLVTKFLL
PLNLLRAFWQSLGVVRRVRPNVVLGMGGYITFPGGMMSVLLGAPLVLHEQNSIAGLANRVLARVADRVLCAFPGALPGAE
WVGNPIRADLAALPSPQARYAERSGPLRVLVVGGSLGAAALNDVVPRALALLPADTRPIVIHQAGAKQIDTLRANYAAVG
IDETHAQAVPFIDDMAAAYAQADLVICRAGAMTVSEVAAAGVAALFVPFPHAVDDHQTTNARFLSERGAALLVPQPSLGP
ASLADTLASLTRAQLADMAAKAREQARPEAAERVADICVAAARA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=355, Percent_Identity=50.7042253521127, Blast_Score=337, Evalue=9e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_RALSO (Q8XVI7)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_520965.1
- ProteinModelPortal:   Q8XVI7
- SMR:   Q8XVI7
- GeneID:   1221692
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc2844
- NMPDR:   fig|267608.1.peg.2844
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   RSOL267608:RSC2844-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 37997; Mature: 37865

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARVSADLPRTLLVMAGGTGGHIFPALSVARLLAARGWQVVWLGNASGMEGQLVPKHGF
CCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCC
PLESVRFGGVRGKGLVTKFLLPLNLLRAFWQSLGVVRRVRPNVVLGMGGYITFPGGMMSV
CHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCHHHHHH
LLGAPLVLHEQNSIAGLANRVLARVADRVLCAFPGALPGAEWVGNPIRADLAALPSPQAR
HHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHCCCCHHH
YAERSGPLRVLVVGGSLGAAALNDVVPRALALLPADTRPIVIHQAGAKQIDTLRANYAAV
HHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHCEEEE
GIDETHAQAVPFIDDMAAAYAQADLVICRAGAMTVSEVAAAGVAALFVPFPHAVDDHQTT
CCCHHHHHHCCCHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHEEECCCCCCCCCCCC
NARFLSERGAALLVPQPSLGPASLADTLASLTRAQLADMAAKAREQARPEAAERVADICV
CHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AAARA
HHHCC
>Mature Secondary Structure 
TARVSADLPRTLLVMAGGTGGHIFPALSVARLLAARGWQVVWLGNASGMEGQLVPKHGF
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCC
PLESVRFGGVRGKGLVTKFLLPLNLLRAFWQSLGVVRRVRPNVVLGMGGYITFPGGMMSV
CHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCHHHHHH
LLGAPLVLHEQNSIAGLANRVLARVADRVLCAFPGALPGAEWVGNPIRADLAALPSPQAR
HHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHCCCCHHH
YAERSGPLRVLVVGGSLGAAALNDVVPRALALLPADTRPIVIHQAGAKQIDTLRANYAAV
HHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHCEEEE
GIDETHAQAVPFIDDMAAAYAQADLVICRAGAMTVSEVAAAGVAALFVPFPHAVDDHQTT
CCCHHHHHHCCCHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHEEECCCCCCCCCCCC
NARFLSERGAALLVPQPSLGPASLADTLASLTRAQLADMAAKAREQARPEAAERVADICV
CHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AAARA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852