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The map label for this gene is ftsW [H]

Identifier: 17547564

GI number: 17547564

Start: 3060492

End: 3061733

Strand: Reverse

Name: ftsW [H]

Synonym: RSc2845

Alternate gene names: 17547564

Gene position: 3061733-3060492 (Counterclockwise)

Preceding gene: 161621732

Following gene: 17547563

Centisome position: 82.38

GC content: 65.38

Gene sequence:

>1242_bases
ATGAGCGACGCCCAGATCAAGCGCAGCGGCTTCATCGGCGCCACCATCGGCAACGCCTGGGAAGGGCTGCGCGACGCCGT
GTCGGGCGTCAAGCCCACGCGCTCCAAGATGATGGAGTACGACCAGCCGCTGCTGTGGGTGTCGATCGTGCTGCTGGGCC
TGGGTCTGGTGATGGTGTATTCGGCGTCGATCGCGCTGCCGGATTCGCCCAAGTACGCCAACTACACCAACGGGCACTTC
CTGTTGCGCCACGCGTTCTCGCTGCTGATCGGCGTGATCGGTGCCGTGGTCGCCTTCCAGATCCCGGTCAAGTTCTGGGA
CAAGTACGCGCCCAAGCTGTTCATCATCGCGCTGGTGCTGCTGGTGGTGGTGCTGATCCCGCACGTGGGCAAGGGCGTGA
ACGGCGCGCGCCGCTGGCTGCCGCTGGGCGTCATGAACTTCCAGCCGTCCGAGCTGATGAAGCTGGCGGTGGTGCTGTAT
GCCGCGAACTACACGGTGCGCAAGCAGGATTGGATGCAGAACGTGCGCAAGGGCTTCCTGCCGATGGGCGTGGCGGTGGC
CTTCGTCGGCTCGCTGCTGCTCCTGGAGCCCGACATGGGCGCCTTCCTGGTGATTGCCGCGGTGGCGATGGGCATCCTGT
TCCTGGGCGGGGTCAACGGCAAGCTGTTCGGCGGGTTGGTGCTCACCGCGGTGTCGACGTTCTCGCTGCTGATCCTGATG
TCGCCGTGGCGGCGCGAGCGGATCTTCGCCTATCTGAATCCGTGGCAGGAAGAATACGCGCAGGGCAAGGCGTACCAGCT
CACTCACTCGCTGATCGCCTTCGGCCGCGGTGAATGGACCGGCGTCGGCCTGGGCGGCAGCATCGAGAAGCTGCACTACC
TGCCGGAGGCGCATACCGACTTCATCCTGGCCGTGATCGGCGAGGAGCTGGGCTTCGTCGGCGTGCTGATCGTGATCCTG
CTGTTCTACTGGATGGTGCGCCGCGCCTTCGAGATCGGCCGCACCGCGCTGCAGCTCGACCGCACCTTCGCCGGCCTGGT
CGCCAAGGGCCTGGGCATCTGGATCGGCTGGCAGGCCTTCATCAACATGGGCGTGAACCTGGGCCTGCTGCCGACCAAGG
GGCTGACGCTGCCGATGGTCAGCTACGGCGGTTCGGGCATCCTGATGAACTGCATGGCGATCGCGCTGCTGCTCCGTATC
GACTACGAGAACCGCGTCCTGATGCGTGGAGGGAAGGTATGA

Upstream 100 bases:

>100_bases
CGGCCTGCGCGAGCTTCGACATGTTCCGCAACTACGAACACCGCGCGCAGGTGTTCCACGAAGCCGTGGCCGCGCTGGCG
GCCGATCGGGGAGTGATGCT

Downstream 100 bases:

>100_bases
CGGCACGCGTGTCGGCCGATCTGCCGCGCACCCTCCTCGTCATGGCCGGCGGCACCGGCGGCCACATCTTCCCCGCGCTG
TCGGTGGCCAGGCTGCTGGC

Product: cell division FtsW transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSDAQIKRSGFIGATIGNAWEGLRDAVSGVKPTRSKMMEYDQPLLWVSIVLLGLGLVMVYSASIALPDSPKYANYTNGHF
LLRHAFSLLIGVIGAVVAFQIPVKFWDKYAPKLFIIALVLLVVVLIPHVGKGVNGARRWLPLGVMNFQPSELMKLAVVLY
AANYTVRKQDWMQNVRKGFLPMGVAVAFVGSLLLLEPDMGAFLVIAAVAMGILFLGGVNGKLFGGLVLTAVSTFSLLILM
SPWRRERIFAYLNPWQEEYAQGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTDFILAVIGEELGFVGVLIVIL
LFYWMVRRAFEIGRTALQLDRTFAGLVAKGLGIWIGWQAFINMGVNLGLLPTKGLTLPMVSYGGSGILMNCMAIALLLRI
DYENRVLMRGGKV

Sequences:

>Translated_413_residues
MSDAQIKRSGFIGATIGNAWEGLRDAVSGVKPTRSKMMEYDQPLLWVSIVLLGLGLVMVYSASIALPDSPKYANYTNGHF
LLRHAFSLLIGVIGAVVAFQIPVKFWDKYAPKLFIIALVLLVVVLIPHVGKGVNGARRWLPLGVMNFQPSELMKLAVVLY
AANYTVRKQDWMQNVRKGFLPMGVAVAFVGSLLLLEPDMGAFLVIAAVAMGILFLGGVNGKLFGGLVLTAVSTFSLLILM
SPWRRERIFAYLNPWQEEYAQGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTDFILAVIGEELGFVGVLIVIL
LFYWMVRRAFEIGRTALQLDRTFAGLVAKGLGIWIGWQAFINMGVNLGLLPTKGLTLPMVSYGGSGILMNCMAIALLLRI
DYENRVLMRGGKV
>Mature_412_residues
SDAQIKRSGFIGATIGNAWEGLRDAVSGVKPTRSKMMEYDQPLLWVSIVLLGLGLVMVYSASIALPDSPKYANYTNGHFL
LRHAFSLLIGVIGAVVAFQIPVKFWDKYAPKLFIIALVLLVVVLIPHVGKGVNGARRWLPLGVMNFQPSELMKLAVVLYA
ANYTVRKQDWMQNVRKGFLPMGVAVAFVGSLLLLEPDMGAFLVIAAVAMGILFLGGVNGKLFGGLVLTAVSTFSLLILMS
PWRRERIFAYLNPWQEEYAQGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTDFILAVIGEELGFVGVLIVILL
FYWMVRRAFEIGRTALQLDRTFAGLVAKGLGIWIGWQAFINMGVNLGLLPTKGLTLPMVSYGGSGILMNCMAIALLLRID
YENRVLMRGGKV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=382, Percent_Identity=45.2879581151832, Blast_Score=315, Evalue=5e-87,
Organism=Escherichia coli, GI1786853, Length=332, Percent_Identity=34.3373493975904, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45309; Mature: 45178

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCEEEECCCCCCEEHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCC
>Mature Secondary Structure 
SDAQIKRSGFIGATIGNAWEGLRDAVSGVKPTRSKMMEYDQPLLWVSIVLLGLGLVMVY
CCCCCHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SASIALPDSPKYANYTNGHFLLRHAFSLLIGVIGAVVAFQIPVKFWDKYAPKLFIIALVL
HCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LVVVLIPHVGKGVNGARRWLPLGVMNFQPSELMKLAVVLYAANYTVRKQDWMQNVRKGFL
HHHHHHHCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
PMGVAVAFVGSLLLLEPDMGAFLVIAAVAMGILFLGGVNGKLFGGLVLTAVSTFSLLILM
HHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SPWRRERIFAYLNPWQEEYAQGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTD
CCCHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCCHH
FILAVIGEELGFVGVLIVILLFYWMVRRAFEIGRTALQLDRTFAGLVAKGLGIWIGWQAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INMGVNLGLLPTKGLTLPMVSYGGSGILMNCMAIALLLRIDYENRVLMRGGKV
HHCCCCEEEECCCCCCEEHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]