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The map label for this gene is trxB [H]

Identifier: 17547061

GI number: 17547061

Start: 2541365

End: 2542321

Strand: Direct

Name: trxB [H]

Synonym: RSc2342

Alternate gene names: 17547061

Gene position: 2541365-2542321 (Clockwise)

Preceding gene: 17547053

Following gene: 17547062

Centisome position: 68.38

GC content: 66.98

Gene sequence:

>957_bases
ATGGCAAAACACGCAAAAGTGCTGATCCTCGGCTCCGGCCCCGCCGGCTACACGGCCGCCATCTACGCCGCCCGGGCCAA
CCTGAACCCGATGCTGATCACCGGCCTGGCGCAGGGCGGCCAGCTGATGACCACCACCGAGGTGGAAAACTGGCCCGCCG
ACAGGGAAGGCCTGCAGGGTCCCGAGCTGATGCAGCGCTTCTTGGAGCACGCCGAGCGCTTCAGCACCGACGTGGTGTTC
GACCATATCCACACCGCGCACCTGACCGAAAAGCCCATCCGTCTGGTGGGGGATTCCGGCGAGTACACCTGCGACGCGCT
GATCATCTCCACCGGCGCCTCGGCCCAGTACCTGGGGCTGCCGTCGGAAGAGACCTTCTCGGGCCGCGGCGTGTCCGCCT
GCGCCACCTGCGACGGCTTCTTCTACAAGGGGCAGGAAGTGGCCGTGGTGGGCGGCGGCAACACCGCCGTGGAAGAAGCG
CTGTACCTGGCCAACATCGCCTCCAAGGTGACGCTGATCCACCGCCGCGACAAGTTCCGCGCCGAGCCCATCCTGGTCGA
CCGCCTGCTCGAGCAGCAGAAGAAGGGCAAGATCGAGATCAAGTACAACACCGTGCTCGACGAAGTGCTCGGCGACGACT
CCGGCGTGACCGGCGTGCGCCTGCGCGGCGTGAACGGCAACGCGACCGGCGCGGAAGAGGTCAGGCTGGCCGGCGTCTTC
ATCGCCATCGGCCACAAGCCGAACACCGACCTGTTCAAGGGCCAGCTGGACATGAACGAAACCGGCTACCTCCGCACGCA
GAGCGGCCTGGTCGGCAACGCCACGGCCACCAACATCCCGGGCGTGTTCGCCGCCGGCGACGTGCAGGACCACATCTACC
GCCAGGCCATCACCAGCGCCGGCACGGGCTGCATGGCCGCGCTGGATGCCCAGCGCTACCTGGAAAACCAGGAATAA

Upstream 100 bases:

>100_bases
GCCGGATTCCGGGGGCCACTTTATAATGGCGCCCTCACCCTCACCTACTCGGCACGGCGGCCATCCAACCCACTCACCCG
CCGCGCACATCGAACGCATC

Downstream 100 bases:

>100_bases
GCGACAGGCGCCTGCGCCACGGGCAACGGCCGATGGGAAGCCCATCGGCCGTTTTGTTTTGTCATGGCGGCCCGGTGCGC
GGGCATTCGTATAATCGACA

Product: thioredoxin reductase oxidoreductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MAKHAKVLILGSGPAGYTAAIYAARANLNPMLITGLAQGGQLMTTTEVENWPADREGLQGPELMQRFLEHAERFSTDVVF
DHIHTAHLTEKPIRLVGDSGEYTCDALIISTGASAQYLGLPSEETFSGRGVSACATCDGFFYKGQEVAVVGGGNTAVEEA
LYLANIASKVTLIHRRDKFRAEPILVDRLLEQQKKGKIEIKYNTVLDEVLGDDSGVTGVRLRGVNGNATGAEEVRLAGVF
IAIGHKPNTDLFKGQLDMNETGYLRTQSGLVGNATATNIPGVFAAGDVQDHIYRQAITSAGTGCMAALDAQRYLENQE

Sequences:

>Translated_318_residues
MAKHAKVLILGSGPAGYTAAIYAARANLNPMLITGLAQGGQLMTTTEVENWPADREGLQGPELMQRFLEHAERFSTDVVF
DHIHTAHLTEKPIRLVGDSGEYTCDALIISTGASAQYLGLPSEETFSGRGVSACATCDGFFYKGQEVAVVGGGNTAVEEA
LYLANIASKVTLIHRRDKFRAEPILVDRLLEQQKKGKIEIKYNTVLDEVLGDDSGVTGVRLRGVNGNATGAEEVRLAGVF
IAIGHKPNTDLFKGQLDMNETGYLRTQSGLVGNATATNIPGVFAAGDVQDHIYRQAITSAGTGCMAALDAQRYLENQE
>Mature_317_residues
AKHAKVLILGSGPAGYTAAIYAARANLNPMLITGLAQGGQLMTTTEVENWPADREGLQGPELMQRFLEHAERFSTDVVFD
HIHTAHLTEKPIRLVGDSGEYTCDALIISTGASAQYLGLPSEETFSGRGVSACATCDGFFYKGQEVAVVGGGNTAVEEAL
YLANIASKVTLIHRRDKFRAEPILVDRLLEQQKKGKIEIKYNTVLDEVLGDDSGVTGVRLRGVNGNATGAEEVRLAGVFI
AIGHKPNTDLFKGQLDMNETGYLRTQSGLVGNATATNIPGVFAAGDVQDHIYRQAITSAGTGCMAALDAQRYLENQE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=68.6900958466454, Blast_Score=450, Evalue=1e-128,
Organism=Escherichia coli, GI87081763, Length=315, Percent_Identity=34.6031746031746, Blast_Score=143, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6321898, Length=326, Percent_Identity=46.319018404908, Blast_Score=283, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6320560, Length=326, Percent_Identity=45.7055214723926, Blast_Score=281, Evalue=1e-76,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34059; Mature: 33928

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKHAKVLILGSGPAGYTAAIYAARANLNPMLITGLAQGGQLMTTTEVENWPADREGLQG
CCCCEEEEEEECCCCCCEEEEEEEECCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCC
PELMQRFLEHAERFSTDVVFDHIHTAHLTEKPIRLVGDSGEYTCDALIISTGASAQYLGL
HHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEEEECCCCEEEECC
PSEETFSGRGVSACATCDGFFYKGQEVAVVGGGNTAVEEALYLANIASKVTLIHRRDKFR
CCCCCCCCCCCEEEEECCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHEEEEEECCCCC
AEPILVDRLLEQQKKGKIEIKYNTVLDEVLGDDSGVTGVRLRGVNGNATGAEEVRLAGVF
CCHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHEEEEEEE
IAIGHKPNTDLFKGQLDMNETGYLRTQSGLVGNATATNIPGVFAAGDVQDHIYRQAITSA
EEECCCCCCCCEECEECCCCCCCEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHC
GTGCMAALDAQRYLENQE
CCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKHAKVLILGSGPAGYTAAIYAARANLNPMLITGLAQGGQLMTTTEVENWPADREGLQG
CCCEEEEEEECCCCCCEEEEEEEECCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCC
PELMQRFLEHAERFSTDVVFDHIHTAHLTEKPIRLVGDSGEYTCDALIISTGASAQYLGL
HHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEEEECCCCEEEECC
PSEETFSGRGVSACATCDGFFYKGQEVAVVGGGNTAVEEALYLANIASKVTLIHRRDKFR
CCCCCCCCCCCEEEEECCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHEEEEEECCCCC
AEPILVDRLLEQQKKGKIEIKYNTVLDEVLGDDSGVTGVRLRGVNGNATGAEEVRLAGVF
CCHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHEEEEEEE
IAIGHKPNTDLFKGQLDMNETGYLRTQSGLVGNATATNIPGVFAAGDVQDHIYRQAITSA
EEECCCCCCCCEECEECCCCCCCEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHC
GTGCMAALDAQRYLENQE
CCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]