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The map label for this gene is lolA [H]

Identifier: 17547059

GI number: 17547059

Start: 2538065

End: 2538712

Strand: Reverse

Name: lolA [H]

Synonym: RSc2340

Alternate gene names: 17547059

Gene position: 2538712-2538065 (Counterclockwise)

Preceding gene: 17547060

Following gene: 17547058

Centisome position: 68.31

GC content: 65.28

Gene sequence:

>648_bases
ATGTTTGTGTTGAAAGCACGTCACCTGATGGCTGCCGGACTGGTGTCGCTGGCAGCGTGGTCGGCCGGCGCCCAGGCCGG
CGCGATCGAGCAGCTCAATGCCTTCGTCAGCAACGTCACCACCGCGCGCGGCGAGTTCGTCCAGCGGCAGGTGAAGGGCG
GCGCCAATGGCAGCCCGCTGCGCGTGGCCGGCACCTCAAGCGGTGACTTCACCTTCTCGCGCCCGGGCCGCTTCGTCTGG
CGCTACCTGAAGCCTTACGAGCAGCAACTGTCGGCCGATGGCCAGATGCTCTACATCTACGACAAGGACCTGAGCCAGGT
CACGGAGCGCAAGCTCGATGCCTCGCTCGGCTCCAGCCCGGCCGCGATCCTGTTCGGCAGCAACGATCTGGCGAAGAACT
TCGTGCTCAAGGAAGGCGGCACCAAGGACGGCATCGACTGGGTCGAGCTGACGCCCAAGGCGAAAGACACCCAGTTCGAG
CGCGTCGCCATCGGCTTCCGCGCGGGCGAGCTGGAGGGCATGGAGTTGCGCGATGCTTTCGGCAACACCACGCTGCTGAC
GTTCTCGCATATCCAGAAGAATCCGCAACTGCCGGCCAGCGCGTTCCGCTTCGTGCCGCCCAAGGGGGCCGACGTCATCA
AGCAGTAA

Upstream 100 bases:

>100_bases
GAAGAGGAATGACGCCGCGGTTACATCGCGTTACCGCATCCCTGGAATGTTCAGGCGCGGCCGGCCACTAACAACAAGAT
CAACTGAAACCGGGATTCCT

Downstream 100 bases:

>100_bases
CGCGACGGGGCCGGTTTTCGACAAGGAGACCGACCATGCGTTTTTCGACTTTCACACCGCTGCGCCGCGCCGTTGCCGTT
GCCGCGACGGTGGCGGCGCT

Product: outer-membrane lipoprotein carrier protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MFVLKARHLMAAGLVSLAAWSAGAQAGAIEQLNAFVSNVTTARGEFVQRQVKGGANGSPLRVAGTSSGDFTFSRPGRFVW
RYLKPYEQQLSADGQMLYIYDKDLSQVTERKLDASLGSSPAAILFGSNDLAKNFVLKEGGTKDGIDWVELTPKAKDTQFE
RVAIGFRAGELEGMELRDAFGNTTLLTFSHIQKNPQLPASAFRFVPPKGADVIKQ

Sequences:

>Translated_215_residues
MFVLKARHLMAAGLVSLAAWSAGAQAGAIEQLNAFVSNVTTARGEFVQRQVKGGANGSPLRVAGTSSGDFTFSRPGRFVW
RYLKPYEQQLSADGQMLYIYDKDLSQVTERKLDASLGSSPAAILFGSNDLAKNFVLKEGGTKDGIDWVELTPKAKDTQFE
RVAIGFRAGELEGMELRDAFGNTTLLTFSHIQKNPQLPASAFRFVPPKGADVIKQ
>Mature_215_residues
MFVLKARHLMAAGLVSLAAWSAGAQAGAIEQLNAFVSNVTTARGEFVQRQVKGGANGSPLRVAGTSSGDFTFSRPGRFVW
RYLKPYEQQLSADGQMLYIYDKDLSQVTERKLDASLGSSPAAILFGSNDLAKNFVLKEGGTKDGIDWVELTPKAKDTQFE
RVAIGFRAGELEGMELRDAFGNTTLLTFSHIQKNPQLPASAFRFVPPKGADVIKQ

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 23347; Mature: 23347

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVLKARHLMAAGLVSLAAWSAGAQAGAIEQLNAFVSNVTTARGEFVQRQVKGGANGSPL
CEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
RVAGTSSGDFTFSRPGRFVWRYLKPYEQQLSADGQMLYIYDKDLSQVTERKLDASLGSSP
EEEECCCCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCC
AAILFGSNDLAKNFVLKEGGTKDGIDWVELTPKAKDTQFERVAIGFRAGELEGMELRDAF
EEEEECCCHHHHHEEECCCCCCCCCCEEEECCCCCCCCEEEEEEEEECCCCCCCCHHHHC
GNTTLLTFSHIQKNPQLPASAFRFVPPKGADVIKQ
CCEEEEEEHHHHCCCCCCHHHEECCCCCCHHHHCC
>Mature Secondary Structure
MFVLKARHLMAAGLVSLAAWSAGAQAGAIEQLNAFVSNVTTARGEFVQRQVKGGANGSPL
CEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
RVAGTSSGDFTFSRPGRFVWRYLKPYEQQLSADGQMLYIYDKDLSQVTERKLDASLGSSP
EEEECCCCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCC
AAILFGSNDLAKNFVLKEGGTKDGIDWVELTPKAKDTQFERVAIGFRAGELEGMELRDAF
EEEEECCCHHHHHEEECCCCCCCCCCEEEECCCCCCCCEEEEEEEEECCCCCCCCHHHHC
GNTTLLTFSHIQKNPQLPASAFRFVPPKGADVIKQ
CCEEEEEEHHHHCCCCCCHHHEECCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA