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The map label for this gene is ftsK

Identifier: 17547060

GI number: 17547060

Start: 2538801

End: 2541146

Strand: Reverse

Name: ftsK

Synonym: RSc2341

Alternate gene names: 17547060

Gene position: 2541146-2538801 (Counterclockwise)

Preceding gene: 17547064

Following gene: 17547059

Centisome position: 68.38

GC content: 68.29

Gene sequence:

>2346_bases
ATGGCCCGAGCTTCCACCACTCCGACGACCCGTACCGATCCCGCTGCGCTGCCGTCCCGCATCGGCCGGCTGCTGGGCGA
GGTCCGCTGGTTCCTGTTGCTGGCGGTGACCATCGCCTTCCTGACCATCCTGCTGTCGTACAACAAGGCCGACCCCGGCT
GGTCCCATGCCAGCCAGGTCGACGACGTGCGCAACCTGGGCGGTCGCGTCGGCGCCTGGTTCGCCGACGTGCTGCTGTTC
GTGTTCGGCGCCTCGGCCTACTGGTGGGCGCTGCTGCTGTTGCGCCGCGTCTGGCGCGGCTGGCGCGAGCTGATGTCCGA
CGAGCGCGTGCCGCGCGCCGCCACGCCGCGCGTGGACGCCGGCGTCACCTGGTTCGGCTTCGCGCTGATCCTGTCGGCCA
GCATGGGCCTGGAAGCCATCCGCATGCATACGCTGCACATGAAGCTGCCGCGCGCGCCGGGCGGCGTGCTGGGCGACCTG
ATCGGCGGATCGCTGCAGCATGCGCTGGGCTTCACCGGCGGCACGCTGCTGCTGCTGCTGATGTTCACGGTGGGCCTGTC
GCTGTTCTTCCATTTCTCCTGGCTGAACCTGGCCGAGCAGATCGGCGCGGGCGTCGAGACGCTGTTCGTCGGCTTCAAGA
CCCGCCGCGAGAACAAGCAGGACCGTGCCATCGGCGAAGCGGCCAAGGTCGAGCGCGAGGAGGTGGTCGAAACCCGCCGC
GTGCGCATCGAGGAGGCGCCGCCGGTGCAGATCGTGCGCCCGGCCGCCGTGGTCAAGAGCGAGCGCGTGGAGCGCGAGAA
GCAGCAGCCGCTGTTCGTCGACATCCAGGATTCCGACCTGCCGGCGCTGGCGCTGCTGGACGCGGTGCCGCCCGCGCAGG
AAACCGTCAGCGCCGAGACGCTGGAATTCACCTCGCGCCTGATCGAGAAGAAGCTCAAGGACTTCGGCGTCGAGGTCACG
GTGGTGGCGGCCTATCCGGGCCCGGTCATCACCCGCTACGAGATCGAGCCGGCCACCGGCGTGAAGGGCAGCCAGATCGT
CAACCTGGCCAAGGATCTGGCGCGCTCGCTGTCGCTGGTGTCGGTCCGCGTGGTGGAGACCATTCCCGGCAAGAACTGCA
TGGGCCTGGAGCTGCCGAACCCGAAGCGGCAGGCAGTGCGCCTGGCGGAGATTCTCGGCTCGCAGGTCTACAACGAAAGC
GCTTCGCAGCTGACGATGGCGCTGGGCAAGGACATCGCCGGCAAGCCGGTGGTGGCGGACCTGGCCAAGATGCCGCACTG
CATGGTGGCCGGTACCACGGGCTCGGGCAAGTCGGTCGGGATCAACGCGATGATCCTGTCGCTGCTGTACAAGGCCCGCG
CGGATGCGGTGCGCCTGATCCTGATCGACCCGAAGATGCTGGAGCTGAGCATCTACGAAGGCATCCCGCACCTGCTGTGC
CCGGTGGTGACCGACATGCGCCAGGCCGGCCACGCCCTGAACTGGGCGGTGGGCGAGATGGAGCGCCGCTACAAGCTGAT
GAGCAAGATGGGCGTGCGCAACCTGGCGGGCTTCAACAAGAAGATCGAAGAGGCCGCCGCGCGCGAGGAGAAGATTCATA
ACCCGTTCAGCCTGACGCCCGACGCGCCCGAGCCGCTCGACAAGCTGCCGATGATCGTCATCGTCATCGACGAGCTGGCC
GACCTGATGATGGTGGTCGGCAAGAAGGTCGAAGAGCTGATCGCGCGGATCGCGCAGAAGGCGCGCGCGGCCGGCATCCA
CCTGGTGCTGGCGACGCAGCGCCCGTCCGTGGACGTGATCACCGGCCTGATCAAGGCCAACGTGCCGACGCGGATCGCCT
TCCAGGTGAGCAGCAAGATCGACTCGCGCACGATTCTCGACCAGCAGGGCGCGGAAGCGCTGCTGGGCATGGGCGACATG
CTGTACCTGGCGCCGGGCACCGGGTTGCCGGTGCGCGTGCATGGGGCTTTCGTGTCGGACGATGAGGTGCACCGCGTGGT
GGAGAACCTCAAGTCGCAGGGCGAGCCGAATTACATCGAGGGCCTCCTCGAGGGCGGCACGGCCGATGGCGAAGGCGGCG
GCGATGGCTTCGGCGGTGGCGCAGGGCTCGCGGGCGGCGGTGCCGGCGAGGCCGATCCGCTGTACGACCAGGCCGTCGAC
GTGGTGCTGAAGAACCGGCGCGCGTCGATCTCGCTGGTGCAGCGCCACCTGCGCATCGGCTACAACCGTGCGGCGCGCCT
GCTCGAAGACATGGAGAAGGCCGGACTGGTGTCGGCCATGTCGGGCAACGGCAACCGCGAAATCCTGGCGCCCAACCGCA
ACGGCAACGTCGTCGAAGAGGAATGA

Upstream 100 bases:

>100_bases
GCGGCAATAGCGCCACGGTGGCGCGTTACAATCGGTCCGTTGTCTTTGCGCAGTCCCAAGCCGAGCGGCGTCCGTGCCGT
GCGGCGCACCCGTTTCCCGC

Downstream 100 bases:

>100_bases
CGCCGCGGTTACATCGCGTTACCGCATCCCTGGAATGTTCAGGCGCGGCCGGCCACTAACAACAAGATCAACTGAAACCG
GGATTCCTATGTTTGTGTTG

Product: cell division ftsk transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 781; Mature: 780

Protein sequence:

>781_residues
MARASTTPTTRTDPAALPSRIGRLLGEVRWFLLLAVTIAFLTILLSYNKADPGWSHASQVDDVRNLGGRVGAWFADVLLF
VFGASAYWWALLLLRRVWRGWRELMSDERVPRAATPRVDAGVTWFGFALILSASMGLEAIRMHTLHMKLPRAPGGVLGDL
IGGSLQHALGFTGGTLLLLLMFTVGLSLFFHFSWLNLAEQIGAGVETLFVGFKTRRENKQDRAIGEAAKVEREEVVETRR
VRIEEAPPVQIVRPAAVVKSERVEREKQQPLFVDIQDSDLPALALLDAVPPAQETVSAETLEFTSRLIEKKLKDFGVEVT
VVAAYPGPVITRYEIEPATGVKGSQIVNLAKDLARSLSLVSVRVVETIPGKNCMGLELPNPKRQAVRLAEILGSQVYNES
ASQLTMALGKDIAGKPVVADLAKMPHCMVAGTTGSGKSVGINAMILSLLYKARADAVRLILIDPKMLELSIYEGIPHLLC
PVVTDMRQAGHALNWAVGEMERRYKLMSKMGVRNLAGFNKKIEEAAAREEKIHNPFSLTPDAPEPLDKLPMIVIVIDELA
DLMMVVGKKVEELIARIAQKARAAGIHLVLATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDM
LYLAPGTGLPVRVHGAFVSDDEVHRVVENLKSQGEPNYIEGLLEGGTADGEGGGDGFGGGAGLAGGGAGEADPLYDQAVD
VVLKNRRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNREILAPNRNGNVVEEE

Sequences:

>Translated_781_residues
MARASTTPTTRTDPAALPSRIGRLLGEVRWFLLLAVTIAFLTILLSYNKADPGWSHASQVDDVRNLGGRVGAWFADVLLF
VFGASAYWWALLLLRRVWRGWRELMSDERVPRAATPRVDAGVTWFGFALILSASMGLEAIRMHTLHMKLPRAPGGVLGDL
IGGSLQHALGFTGGTLLLLLMFTVGLSLFFHFSWLNLAEQIGAGVETLFVGFKTRRENKQDRAIGEAAKVEREEVVETRR
VRIEEAPPVQIVRPAAVVKSERVEREKQQPLFVDIQDSDLPALALLDAVPPAQETVSAETLEFTSRLIEKKLKDFGVEVT
VVAAYPGPVITRYEIEPATGVKGSQIVNLAKDLARSLSLVSVRVVETIPGKNCMGLELPNPKRQAVRLAEILGSQVYNES
ASQLTMALGKDIAGKPVVADLAKMPHCMVAGTTGSGKSVGINAMILSLLYKARADAVRLILIDPKMLELSIYEGIPHLLC
PVVTDMRQAGHALNWAVGEMERRYKLMSKMGVRNLAGFNKKIEEAAAREEKIHNPFSLTPDAPEPLDKLPMIVIVIDELA
DLMMVVGKKVEELIARIAQKARAAGIHLVLATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDM
LYLAPGTGLPVRVHGAFVSDDEVHRVVENLKSQGEPNYIEGLLEGGTADGEGGGDGFGGGAGLAGGGAGEADPLYDQAVD
VVLKNRRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNREILAPNRNGNVVEEE
>Mature_780_residues
ARASTTPTTRTDPAALPSRIGRLLGEVRWFLLLAVTIAFLTILLSYNKADPGWSHASQVDDVRNLGGRVGAWFADVLLFV
FGASAYWWALLLLRRVWRGWRELMSDERVPRAATPRVDAGVTWFGFALILSASMGLEAIRMHTLHMKLPRAPGGVLGDLI
GGSLQHALGFTGGTLLLLLMFTVGLSLFFHFSWLNLAEQIGAGVETLFVGFKTRRENKQDRAIGEAAKVEREEVVETRRV
RIEEAPPVQIVRPAAVVKSERVEREKQQPLFVDIQDSDLPALALLDAVPPAQETVSAETLEFTSRLIEKKLKDFGVEVTV
VAAYPGPVITRYEIEPATGVKGSQIVNLAKDLARSLSLVSVRVVETIPGKNCMGLELPNPKRQAVRLAEILGSQVYNESA
SQLTMALGKDIAGKPVVADLAKMPHCMVAGTTGSGKSVGINAMILSLLYKARADAVRLILIDPKMLELSIYEGIPHLLCP
VVTDMRQAGHALNWAVGEMERRYKLMSKMGVRNLAGFNKKIEEAAAREEKIHNPFSLTPDAPEPLDKLPMIVIVIDELAD
LMMVVGKKVEELIARIAQKARAAGIHLVLATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDML
YLAPGTGLPVRVHGAFVSDDEVHRVVENLKSQGEPNYIEGLLEGGTADGEGGGDGFGGGAGLAGGGAGEADPLYDQAVDV
VLKNRRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNREILAPNRNGNVVEEE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain

Homologues:

Organism=Escherichia coli, GI1787117, Length=498, Percent_Identity=63.4538152610442, Blast_Score=605, Evalue=1e-174,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSK2_RALSO (Q8XWX9)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_520462.1
- ProteinModelPortal:   Q8XWX9
- GeneID:   1221187
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc2341
- NMPDR:   fig|267608.1.peg.2341
- HOGENOM:   HBG662140
- OMA:   FKVMDVT
- ProtClustDB:   CLSK2302647
- BioCyc:   RSOL267608:RSC2341-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- SMART:   SM00382
- SMART:   SM00843

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE

EC number: NA

Molecular weight: Translated: 84611; Mature: 84480

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x166f34d4)-; HASH(0xe7a9c74)-; HASH(0xe7c1bfc)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARASTTPTTRTDPAALPSRIGRLLGEVRWFLLLAVTIAFLTILLSYNKADPGWSHASQV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
DDVRNLGGRVGAWFADVLLFVFGASAYWWALLLLRRVWRGWRELMSDERVPRAATPRVDA
HHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GVTWFGFALILSASMGLEAIRMHTLHMKLPRAPGGVLGDLIGGSLQHALGFTGGTLLLLL
CHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
MFTVGLSLFFHFSWLNLAEQIGAGVETLFVGFKTRRENKQDRAIGEAAKVEREEVVETRR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VRIEEAPPVQIVRPAAVVKSERVEREKQQPLFVDIQDSDLPALALLDAVPPAQETVSAET
HCCCCCCCCEEECHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCHHHHHHHHH
LEFTSRLIEKKLKDFGVEVTVVAAYPGPVITRYEIEPATGVKGSQIVNLAKDLARSLSLV
HHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
SVRVVETIPGKNCMGLELPNPKRQAVRLAEILGSQVYNESASQLTMALGKDIAGKPVVAD
HEEEEHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHH
LAKMPHCMVAGTTGSGKSVGINAMILSLLYKARADAVRLILIDPKMLELSIYEGIPHLLC
HHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCEEEHHHHHCCHHHHH
PVVTDMRQAGHALNWAVGEMERRYKLMSKMGVRNLAGFNKKIEEAAAREEKIHNPFSLTP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DAPEPLDKLPMIVIVIDELADLMMVVGKKVEELIARIAQKARAAGIHLVLATQRPSVDVI
CCCCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHH
TGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDMLYLAPGTGLPVRVHGAFVSD
HHHHHCCCCCEEEEEEHHCCCHHHHHHHCCHHHHHCCCCEEEECCCCCCCEEEEEEECCC
DEVHRVVENLKSQGEPNYIEGLLEGGTADGEGGGDGFGGGAGLAGGGAGEADPLYDQAVD
HHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
VVLKNRRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNREILAPNRNGNVVEE
HHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEECCCCCCEEECCCCCCCCCCC
E
H
>Mature Secondary Structure 
ARASTTPTTRTDPAALPSRIGRLLGEVRWFLLLAVTIAFLTILLSYNKADPGWSHASQV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
DDVRNLGGRVGAWFADVLLFVFGASAYWWALLLLRRVWRGWRELMSDERVPRAATPRVDA
HHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GVTWFGFALILSASMGLEAIRMHTLHMKLPRAPGGVLGDLIGGSLQHALGFTGGTLLLLL
CHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
MFTVGLSLFFHFSWLNLAEQIGAGVETLFVGFKTRRENKQDRAIGEAAKVEREEVVETRR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VRIEEAPPVQIVRPAAVVKSERVEREKQQPLFVDIQDSDLPALALLDAVPPAQETVSAET
HCCCCCCCCEEECHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCHHHHHHHHH
LEFTSRLIEKKLKDFGVEVTVVAAYPGPVITRYEIEPATGVKGSQIVNLAKDLARSLSLV
HHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
SVRVVETIPGKNCMGLELPNPKRQAVRLAEILGSQVYNESASQLTMALGKDIAGKPVVAD
HEEEEHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHH
LAKMPHCMVAGTTGSGKSVGINAMILSLLYKARADAVRLILIDPKMLELSIYEGIPHLLC
HHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCEEEHHHHHCCHHHHH
PVVTDMRQAGHALNWAVGEMERRYKLMSKMGVRNLAGFNKKIEEAAAREEKIHNPFSLTP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DAPEPLDKLPMIVIVIDELADLMMVVGKKVEELIARIAQKARAAGIHLVLATQRPSVDVI
CCCCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHH
TGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDMLYLAPGTGLPVRVHGAFVSD
HHHHHCCCCCEEEEEEHHCCCHHHHHHHCCHHHHHCCCCEEEECCCCCCCEEEEEEECCC
DEVHRVVENLKSQGEPNYIEGLLEGGTADGEGGGDGFGGGAGLAGGGAGEADPLYDQAVD
HHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
VVLKNRRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNREILAPNRNGNVVEE
HHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEECCCCCCEEECCCCCCCCCCC
E
H

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852