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The map label for this gene is nadD [H]

Identifier: 17546912

GI number: 17546912

Start: 2375732

End: 2376427

Strand: Direct

Name: nadD [H]

Synonym: RSc2193

Alternate gene names: 17546912

Gene position: 2375732-2376427 (Clockwise)

Preceding gene: 17546911

Following gene: 17546913

Centisome position: 63.93

GC content: 71.55

Gene sequence:

>696_bases
ATGACGCCTCCCGATCTTGGCCGCCCCTATCGCCTGGGCCTGCTGGGCGGTACCTTCGACCCGCCGCACGTCGGCCATCT
CGCCCTGGCCGAACTGTGCATCGCCCAGCTCGATCTGGACGAGCTGGTATGGATCCCGACCGGCATGTCGTGGCAGAAGG
CCGCCGACATCACGCCCGCCCCGCTGCGGCTGGCGATGACCGAGCTGGCGGCCCGGGCCGTGCGCCCAGGCCGCGCCCGC
GTGCGCGTCAGCACCATGGAGGTCGAGCGCAGCGGCCCCAGCTACACCATCGACACCGTGCGCGAGCTGCGCGGCGCCTA
TGGCCCCGACACCTCCATGGCCTGGCTGATGGGCGCCGACCAGCTGGTCGGCCTGGACACCTGGCACGGCTGGCAGGACC
TGTTCGAATACGTGCACCTGTGCGTGGCCACGCGCCCCGGTTTCGACCTGCACGCGCTGCATGCGCCGGTGCAGCTCGAG
CTCGACATGCGCCGCGCCGGCCCGGCATTGATACAATGCGCACCCGCCGGCCGCATGTGGATCGACCAGACCCTGGCCGT
CGACCTGTCGTCCACCCGCCTGCGCCAGCAGCTTGCCGCCGGCGAGCGCTGCGACGCCGACCTGCCGGCCGGCGTGGCTG
ACCTGATCCAGTCGCATGCGCTGTACCGCCGTGCCGATGGCACGGTCAGTGCTTGA

Upstream 100 bases:

>100_bases
CGATGCCGCCCGTGGCCAACTGGCGCTACGACTGGCAGCCGGAGCCGGGCTCGCCGGAAGCGGCGCTCTACACCGACTTC
CTGCCGGCGCGCGATTGGGT

Downstream 100 bases:

>100_bases
TCCGATTTTTGACCGCCTTTTTCCCGCCCCCAACGTTCTTCTTACTCAGTATGGATATTCGCAAACTACAACGCGTGATC
GTCGACGCGCTCGAAGACGT

Product: nicotinic acid mononucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTPPDLGRPYRLGLLGGTFDPPHVGHLALAELCIAQLDLDELVWIPTGMSWQKAADITPAPLRLAMTELAARAVRPGRAR
VRVSTMEVERSGPSYTIDTVRELRGAYGPDTSMAWLMGADQLVGLDTWHGWQDLFEYVHLCVATRPGFDLHALHAPVQLE
LDMRRAGPALIQCAPAGRMWIDQTLAVDLSSTRLRQQLAAGERCDADLPAGVADLIQSHALYRRADGTVSA

Sequences:

>Translated_231_residues
MTPPDLGRPYRLGLLGGTFDPPHVGHLALAELCIAQLDLDELVWIPTGMSWQKAADITPAPLRLAMTELAARAVRPGRAR
VRVSTMEVERSGPSYTIDTVRELRGAYGPDTSMAWLMGADQLVGLDTWHGWQDLFEYVHLCVATRPGFDLHALHAPVQLE
LDMRRAGPALIQCAPAGRMWIDQTLAVDLSSTRLRQQLAAGERCDADLPAGVADLIQSHALYRRADGTVSA
>Mature_230_residues
TPPDLGRPYRLGLLGGTFDPPHVGHLALAELCIAQLDLDELVWIPTGMSWQKAADITPAPLRLAMTELAARAVRPGRARV
RVSTMEVERSGPSYTIDTVRELRGAYGPDTSMAWLMGADQLVGLDTWHGWQDLFEYVHLCVATRPGFDLHALHAPVQLEL
DMRRAGPALIQCAPAGRMWIDQTLAVDLSSTRLRQQLAAGERCDADLPAGVADLIQSHALYRRADGTVSA

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) [H]

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family [H]

Homologues:

Organism=Escherichia coli, GI1786858, Length=212, Percent_Identity=31.6037735849057, Blast_Score=114, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.18 [H]

Molecular weight: Translated: 25239; Mature: 25108

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPDLGRPYRLGLLGGTFDPPHVGHLALAELCIAQLDLDELVWIPTGMSWQKAADITPA
CCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHEEEECCCCCHHHHCCCCCH
PLRLAMTELAARAVRPGRARVRVSTMEVERSGPSYTIDTVRELRGAYGPDTSMAWLMGAD
HHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCEEHHHHHHHHCCCCCCCCCCEEECCC
QLVGLDTWHGWQDLFEYVHLCVATRPGFDLHALHAPVQLELDMRRAGPALIQCAPAGRMW
CEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEHHHCCCEEEEECCCCCCC
IDQTLAVDLSSTRLRQQLAAGERCDADLPAGVADLIQSHALYRRADGTVSA
HHHHHEECCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TPPDLGRPYRLGLLGGTFDPPHVGHLALAELCIAQLDLDELVWIPTGMSWQKAADITPA
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHEEEECCCCCHHHHCCCCCH
PLRLAMTELAARAVRPGRARVRVSTMEVERSGPSYTIDTVRELRGAYGPDTSMAWLMGAD
HHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCEEHHHHHHHHCCCCCCCCCCEEECCC
QLVGLDTWHGWQDLFEYVHLCVATRPGFDLHALHAPVQLELDMRRAGPALIQCAPAGRMW
CEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEHHHCCCEEEEECCCCCCC
IDQTLAVDLSSTRLRQQLAAGERCDADLPAGVADLIQSHALYRRADGTVSA
HHHHHEECCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA