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The map label for this gene is dalD

Identifier: 17546848

GI number: 17546848

Start: 2309151

End: 2310548

Strand: Reverse

Name: dalD

Synonym: RSc2129

Alternate gene names: 17546848

Gene position: 2310548-2309151 (Counterclockwise)

Preceding gene: 17546849

Following gene: 17546847

Centisome position: 62.17

GC content: 67.81

Gene sequence:

>1398_bases
ATGACGCGGTCGTCCCTCGCGCGTGCGCCAGTGCTGCTGCATATTGGCGCCGGATCTTTCCATCGTGCGCACCAGGCGTG
GTATCTGCATCGCGTCAACGCGGCCGTGCCTCCCGGCGAGCGCTGGACGCTGACGGTCGGGAACATTCGCGACGACATGC
ACGCGACACTCGCCGCGCTGGCCGCGCAGCAGGGTGCCTACACGCTCGAGACCGTCACGCCGCAAGGCGAGCGTGCGTAT
GAGACGATCCGCTCGATCGCGCGGGTGCTGCCCTGGTCCGCCGATCTTGCCGCGCTCATCAATACGGGCGCCGATCCCGC
GTGCCGGATCGTGTCGTTTACGGTCACCGAAGGCGGGTATTACCTCGACGAGCACGATCGTCTCGATGTCACGCATCCCG
ATCTCGCGGCCGACCTGCGGGGCGCCCGCTCGACGCTATACGGCGCATTGGCCGCGTTGCTCGCCGAGCGCCGCCAGCGC
GGAGCCGGGCCGCTCACGCTGCAGAGTTGCGACAATCTGCGCAGCAACGGCGCGCGTTTTCGCGCGGGCATGCGCGCGTT
CCTCGCGCTGCGCGGCGACGCAGCGCTCCTCGCGTGGTTCGATGCCAACGTATCGTGCCCGAGCGCGATGGTCGACCGGA
TCACGCCGCGGCCGACCGACGACGTCCGCACGCGCGTGCACGCGGCCACCGGCGTCGACGACCGCTGCCCGGTCATGGGC
GAATCCTTCATCCAATGGGTGATCGAGGACAACTTCATCGCCGGCCGGCCGGCATGGGAGATCGCGGGCGCGGAGATCGT
CGCCGATGTGCATCCGTACGAAGAGGCGAAGATCCGGATCCTGAATGCGACGCACAGCTGCATCGCCTGGGCGGGCACGC
TCGCGGGACTCACCTACATTCACGAAGGGATGCGTGATGCGGCCATTTATCGCTTCGCCTACGACTACGTCACCGACGAC
GTGATTCCCTGCCTGACGCCGAGCCCGCTGGATCTCGAGCGCTATCGGGACGTCGTGCTCGAGCGCTTCGGCAATCCGTA
CGTGCTCGACACCAACCAGCGTGTCGCCGCCGATGGCTTCTCGAAAATCCCCGGCTTCATCGCACCGACGCTCGCCGAAT
GCTTTGCGCGCGGCGCCGATCCGGTCGCGACCGCGGTGTTGCCGGCGCTGTTTCTGGGCTTCCTTGAAGGTTGGGCGCGC
GGCACCTTGCCCTACGTATACCAGGACGGCGTGATGGATGGCGCCGCCGCACGCAGCATCGTCGAGGCTCCGGATTCCGT
TGCCGCGTTCTGTTCAGATCGCCAATTGTGGGGTTCGCTTGCGGGCCGCGACGCGCTTGTCCAGGCGGTGCGTGCGGGAC
GCGCGCGCGTTGAAGCATGGCGAGCCGCACGCCGCTGA

Upstream 100 bases:

>100_bases
TTCGTGCTCATCTTGACATTCTTTTTTTTGGATTGGATCATTGGCTCAAAAGTTGAACAAATGTTCATTTCAGGCTGCGA
GCAGCCGTCAGGAGACACGG

Downstream 100 bases:

>100_bases
CGCCGGCGTGCGCGCTGGGGATCCACCGGCATGACACGCCATCCGTCGCGCGGTTAAAGTAGCGGCTCGCCAATTGCCGA
ATCGATCGCGCCATGTACCT

Product: D-arabinitol dehydrogenase oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MTRSSLARAPVLLHIGAGSFHRAHQAWYLHRVNAAVPPGERWTLTVGNIRDDMHATLAALAAQQGAYTLETVTPQGERAY
ETIRSIARVLPWSADLAALINTGADPACRIVSFTVTEGGYYLDEHDRLDVTHPDLAADLRGARSTLYGALAALLAERRQR
GAGPLTLQSCDNLRSNGARFRAGMRAFLALRGDAALLAWFDANVSCPSAMVDRITPRPTDDVRTRVHAATGVDDRCPVMG
ESFIQWVIEDNFIAGRPAWEIAGAEIVADVHPYEEAKIRILNATHSCIAWAGTLAGLTYIHEGMRDAAIYRFAYDYVTDD
VIPCLTPSPLDLERYRDVVLERFGNPYVLDTNQRVAADGFSKIPGFIAPTLAECFARGADPVATAVLPALFLGFLEGWAR
GTLPYVYQDGVMDGAAARSIVEAPDSVAAFCSDRQLWGSLAGRDALVQAVRAGRARVEAWRAARR

Sequences:

>Translated_465_residues
MTRSSLARAPVLLHIGAGSFHRAHQAWYLHRVNAAVPPGERWTLTVGNIRDDMHATLAALAAQQGAYTLETVTPQGERAY
ETIRSIARVLPWSADLAALINTGADPACRIVSFTVTEGGYYLDEHDRLDVTHPDLAADLRGARSTLYGALAALLAERRQR
GAGPLTLQSCDNLRSNGARFRAGMRAFLALRGDAALLAWFDANVSCPSAMVDRITPRPTDDVRTRVHAATGVDDRCPVMG
ESFIQWVIEDNFIAGRPAWEIAGAEIVADVHPYEEAKIRILNATHSCIAWAGTLAGLTYIHEGMRDAAIYRFAYDYVTDD
VIPCLTPSPLDLERYRDVVLERFGNPYVLDTNQRVAADGFSKIPGFIAPTLAECFARGADPVATAVLPALFLGFLEGWAR
GTLPYVYQDGVMDGAAARSIVEAPDSVAAFCSDRQLWGSLAGRDALVQAVRAGRARVEAWRAARR
>Mature_464_residues
TRSSLARAPVLLHIGAGSFHRAHQAWYLHRVNAAVPPGERWTLTVGNIRDDMHATLAALAAQQGAYTLETVTPQGERAYE
TIRSIARVLPWSADLAALINTGADPACRIVSFTVTEGGYYLDEHDRLDVTHPDLAADLRGARSTLYGALAALLAERRQRG
AGPLTLQSCDNLRSNGARFRAGMRAFLALRGDAALLAWFDANVSCPSAMVDRITPRPTDDVRTRVHAATGVDDRCPVMGE
SFIQWVIEDNFIAGRPAWEIAGAEIVADVHPYEEAKIRILNATHSCIAWAGTLAGLTYIHEGMRDAAIYRFAYDYVTDDV
IPCLTPSPLDLERYRDVVLERFGNPYVLDTNQRVAADGFSKIPGFIAPTLAECFARGADPVATAVLPALFLGFLEGWARG
TLPYVYQDGVMDGAAARSIVEAPDSVAAFCSDRQLWGSLAGRDALVQAVRAGRARVEAWRAARR

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1788497, Length=358, Percent_Identity=36.8715083798883, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1787823, Length=360, Percent_Identity=36.1111111111111, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1790779, Length=361, Percent_Identity=35.4570637119114, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI48994885, Length=426, Percent_Identity=26.9953051643192, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790028, Length=231, Percent_Identity=25.5411255411255, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324401, Length=366, Percent_Identity=39.6174863387978, Blast_Score=259, Evalue=7e-70,
Organism=Saccharomyces cerevisiae, GI6320765, Length=366, Percent_Identity=39.6174863387978, Blast_Score=259, Evalue=7e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DALD_RALSO (P58708)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_520250.1
- ProteinModelPortal:   P58708
- SMR:   P58708
- GeneID:   1220971
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc2129
- NMPDR:   fig|267608.1.peg.2129
- HOGENOM:   HBG510279
- OMA:   IARVLPW
- ProtClustDB:   CLSK889158
- BioCyc:   RSOL267608:RSC2129-MONOMER
- BRENDA:   1.1.1.11
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR013131
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PRINTS:   PR00084

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C; SSF48179 6DGDH_C_like

EC number: =1.1.1.11

Molecular weight: Translated: 50631; Mature: 50500

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00974 MANNITOL_DHGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSSLARAPVLLHIGAGSFHRAHQAWYLHRVNAAVPPGERWTLTVGNIRDDMHATLAAL
CCCCHHCCCCEEEEECCCCHHHHHHHHHHEECCCCCCCCCEEEEEECCCCHHHHHHHHHH
AAQQGAYTLETVTPQGERAYETIRSIARVLPWSADLAALINTGADPACRIVSFTVTEGGY
HHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEEEECCCE
YLDEHDRLDVTHPDLAADLRGARSTLYGALAALLAERRQRGAGPLTLQSCDNLRSNGARF
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCHHH
RAGMRAFLALRGDAALLAWFDANVSCPSAMVDRITPRPTDDVRTRVHAATGVDDRCPVMG
HHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHH
ESFIQWVIEDNFIAGRPAWEIAGAEIVADVHPYEEAKIRILNATHSCIAWAGTLAGLTYI
HHHHHHHHHCCEECCCCCHHHCCCCEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHH
HEGMRDAAIYRFAYDYVTDDVIPCLTPSPLDLERYRDVVLERFGNPYVLDTNQRVAADGF
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCHHHCCH
SKIPGFIAPTLAECFARGADPVATAVLPALFLGFLEGWARGTLPYVYQDGVMDGAAARSI
HHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHH
VEAPDSVAAFCSDRQLWGSLAGRDALVQAVRAGRARVEAWRAARR
HHCCHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRSSLARAPVLLHIGAGSFHRAHQAWYLHRVNAAVPPGERWTLTVGNIRDDMHATLAAL
CCCHHCCCCEEEEECCCCHHHHHHHHHHEECCCCCCCCCEEEEEECCCCHHHHHHHHHH
AAQQGAYTLETVTPQGERAYETIRSIARVLPWSADLAALINTGADPACRIVSFTVTEGGY
HHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEEEECCCE
YLDEHDRLDVTHPDLAADLRGARSTLYGALAALLAERRQRGAGPLTLQSCDNLRSNGARF
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCHHH
RAGMRAFLALRGDAALLAWFDANVSCPSAMVDRITPRPTDDVRTRVHAATGVDDRCPVMG
HHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHH
ESFIQWVIEDNFIAGRPAWEIAGAEIVADVHPYEEAKIRILNATHSCIAWAGTLAGLTYI
HHHHHHHHHCCEECCCCCHHHCCCCEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHH
HEGMRDAAIYRFAYDYVTDDVIPCLTPSPLDLERYRDVVLERFGNPYVLDTNQRVAADGF
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCHHHCCH
SKIPGFIAPTLAECFARGADPVATAVLPALFLGFLEGWARGTLPYVYQDGVMDGAAARSI
HHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHH
VEAPDSVAAFCSDRQLWGSLAGRDALVQAVRAGRARVEAWRAARR
HHCCHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852