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The map label for this gene is dalK [H]

Identifier: 17546847

GI number: 17546847

Start: 2307583

End: 2309058

Strand: Reverse

Name: dalK [H]

Synonym: RSc2128

Alternate gene names: 17546847

Gene position: 2309058-2307583 (Counterclockwise)

Preceding gene: 17546848

Following gene: 17546846

Centisome position: 62.13

GC content: 70.33

Gene sequence:

>1476_bases
ATGTACCTAGGCATTGACCTCGGCACCTCGGAAGTGAAGGTGCTGCTGCTCGCCCCCGACGGCACCGTCGTGGGTACAGC
GGGCGCCCCGTTCACGGTGTCGCGACCGCATCCGCGCTGGGCGGAGCAGCACCCGGAAGACTGGTGGCAGGGCACGCTCG
CTGCGCTGGGCATGCTGCGCGCGCGCTGTCCGGACGCGTTCGCGCGGGTGCGCGGCATCGGTCTGTCCGGTCAGATGCAT
GGCGCGGTGCTGCTCGACCAGGCAGACCGCGTGCTGCGCCCGGCGATCCTGTGGAACGACATGCGCAGCGACGACGAATG
CGCGCTCCTGACGGAACGCGCGCCCGATCTGCATGCAATTGCCGGCAATCTCGCGATGCCGGGTTTCACCGCGCCGAAGC
TGCTCTGGGTCGCGCGGCATGAGCCCGACGTGTTCGCGGCAACGACCTGCGTGCTGCTGCCGAAGGACTATCTGCGCTTC
AGGCTGACCGGCGCCAAGGTGTCCGACCCGTCCGACGCGGCCGGGACGCTTTGGCTCGACGTTGCGCGTCGTGACTGGTC
GGACGCGCTGCTTGCCGCGTGCGATCTGTCGCGTGACCAGATGCCGAGGCTCGTCGAAGGCAACGCGCCGTCCGGCACTC
TGCGCGCGGACCTCGCGCGCGAACTCGGCCTGGACCCGCGCGTCGTCGTTGCAGGCGGTGGCGGCGACAACGCGGCGAGC
GCGCTCGGTATCGGCGCGACGCACGCGGGCGACGGCTTCGTGTCGCTCGGCACGTCGGGTGTTCTGAGCATCGTCAGCGA
TCGCTTCACGCCCAATCCGGCGTTGGCGACGCATGCGTTCTGTCACGCGATTCCGGAGCGTTGGCAGCTGATGACGGTCG
TGCTGTCGGCGGCGAGCTGCCTGCGCTGGATCTGCACGCTGACCGGCACCGATGAGCCGACGCTGCTCGCCGAGGTTGAG
CGGCTCGACCCGGGCGCGTGCGCGCAAGCGCCGCTTTTCCTGCCCTATCTGTCCGGCGAACGGACGCCGCACAATGATCC
GTATGCGCAGGGCGTGTTCTTCGGCATGACGCACGCAACCGAGCGCGCGCATCTTGGCTATGCGGTGCTCGAAGGCGTCA
CGCTCGGCTTCGCGGACGGTTTCGACGCGCTGCGCGGCATCGAGACGGACGCCCTGTCGCTGATCGGCGGCGGTGCCCGC
AGCCAGTATTGGGCGCAGATGATCGCCGATGCGCTGAACGTGCGCACGCGCCAGCATGGCGGCGGCGAGACCGGCGCGGC
GCTCGGTGCGGCCCGGCTGGGCTGGCTTGCCGTCGGCGGCGATCCGGACACCGTGCTGGCCAAGCCGCCGGTGTGCGCGG
AATATGCGCCGAACGCGGCGCGTCACGCCGCGCTTTGCGAGCGGCTCGTCGCGTTCCGTGAGCTGTACCGGCACGTGCAG
CCGCTGTATGAGCCGTCGCGGCCGCGACTGGCCTGA

Upstream 100 bases:

>100_bases
GCCGCTGACGCCGGCGTGCGCGCTGGGGATCCACCGGCATGACACGCCATCCGTCGCGCGGTTAAAGTAGCGGCTCGCCA
ATTGCCGAATCGATCGCGCC

Downstream 100 bases:

>100_bases
GCCCGACTGCGGTACAGTGCGTATCGTTCCCGTACGCAGACCCGACTGTCCTTCCACCATCGTGCCCAAGCCCACAGAAA
AACTCGATCTGGCGACCCGA

Product: D-arabinitol kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MYLGIDLGTSEVKVLLLAPDGTVVGTAGAPFTVSRPHPRWAEQHPEDWWQGTLAALGMLRARCPDAFARVRGIGLSGQMH
GAVLLDQADRVLRPAILWNDMRSDDECALLTERAPDLHAIAGNLAMPGFTAPKLLWVARHEPDVFAATTCVLLPKDYLRF
RLTGAKVSDPSDAAGTLWLDVARRDWSDALLAACDLSRDQMPRLVEGNAPSGTLRADLARELGLDPRVVVAGGGGDNAAS
ALGIGATHAGDGFVSLGTSGVLSIVSDRFTPNPALATHAFCHAIPERWQLMTVVLSAASCLRWICTLTGTDEPTLLAEVE
RLDPGACAQAPLFLPYLSGERTPHNDPYAQGVFFGMTHATERAHLGYAVLEGVTLGFADGFDALRGIETDALSLIGGGAR
SQYWAQMIADALNVRTRQHGGGETGAALGAARLGWLAVGGDPDTVLAKPPVCAEYAPNAARHAALCERLVAFRELYRHVQ
PLYEPSRPRLA

Sequences:

>Translated_491_residues
MYLGIDLGTSEVKVLLLAPDGTVVGTAGAPFTVSRPHPRWAEQHPEDWWQGTLAALGMLRARCPDAFARVRGIGLSGQMH
GAVLLDQADRVLRPAILWNDMRSDDECALLTERAPDLHAIAGNLAMPGFTAPKLLWVARHEPDVFAATTCVLLPKDYLRF
RLTGAKVSDPSDAAGTLWLDVARRDWSDALLAACDLSRDQMPRLVEGNAPSGTLRADLARELGLDPRVVVAGGGGDNAAS
ALGIGATHAGDGFVSLGTSGVLSIVSDRFTPNPALATHAFCHAIPERWQLMTVVLSAASCLRWICTLTGTDEPTLLAEVE
RLDPGACAQAPLFLPYLSGERTPHNDPYAQGVFFGMTHATERAHLGYAVLEGVTLGFADGFDALRGIETDALSLIGGGAR
SQYWAQMIADALNVRTRQHGGGETGAALGAARLGWLAVGGDPDTVLAKPPVCAEYAPNAARHAALCERLVAFRELYRHVQ
PLYEPSRPRLA
>Mature_491_residues
MYLGIDLGTSEVKVLLLAPDGTVVGTAGAPFTVSRPHPRWAEQHPEDWWQGTLAALGMLRARCPDAFARVRGIGLSGQMH
GAVLLDQADRVLRPAILWNDMRSDDECALLTERAPDLHAIAGNLAMPGFTAPKLLWVARHEPDVFAATTCVLLPKDYLRF
RLTGAKVSDPSDAAGTLWLDVARRDWSDALLAACDLSRDQMPRLVEGNAPSGTLRADLARELGLDPRVVVAGGGGDNAAS
ALGIGATHAGDGFVSLGTSGVLSIVSDRFTPNPALATHAFCHAIPERWQLMTVVLSAASCLRWICTLTGTDEPTLLAEVE
RLDPGACAQAPLFLPYLSGERTPHNDPYAQGVFFGMTHATERAHLGYAVLEGVTLGFADGFDALRGIETDALSLIGGGAR
SQYWAQMIADALNVRTRQHGGGETGAALGAARLGWLAVGGDPDTVLAKPPVCAEYAPNAARHAALCERLVAFRELYRHVQ
PLYEPSRPRLA

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393575, Length=434, Percent_Identity=21.889400921659, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI42794763, Length=441, Percent_Identity=22.4489795918367, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI4504007, Length=441, Percent_Identity=22.6757369614512, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI189409120, Length=441, Percent_Identity=22.6757369614512, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI18860918, Length=345, Percent_Identity=24.6376811594203, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI164663830, Length=277, Percent_Identity=25.6317689530686, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI164663828, Length=277, Percent_Identity=25.6317689530686, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789987, Length=487, Percent_Identity=53.1827515400411, Blast_Score=466, Evalue=1e-132,
Organism=Escherichia coli, GI1790005, Length=443, Percent_Identity=27.313769751693, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1790361, Length=480, Percent_Identity=23.3333333333333, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1789168, Length=481, Percent_Identity=26.4033264033264, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787789, Length=297, Percent_Identity=26.2626262626263, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17535599, Length=442, Percent_Identity=24.2081447963801, Blast_Score=95, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6321633, Length=336, Percent_Identity=25.5952380952381, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24657106, Length=467, Percent_Identity=23.1263383297645, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24657102, Length=467, Percent_Identity=23.1263383297645, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 52348; Mature: 52348

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLGIDLGTSEVKVLLLAPDGTVVGTAGAPFTVSRPHPRWAEQHPEDWWQGTLAALGMLR
CEEEEECCCCCEEEEEECCCCCEEECCCCCEECCCCCCCHHHCCCHHHHHHHHHHHHHHH
ARCPDAFARVRGIGLSGQMHGAVLLDQADRVLRPAILWNDMRSDDECALLTERAPDLHAI
HHCCHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHH
AGNLAMPGFTAPKLLWVARHEPDVFAATTCVLLPKDYLRFRLTGAKVSDPSDAAGTLWLD
HCCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCHHEEEEECCCCCCCCCCCCCEEEEE
VARRDWSDALLAACDLSRDQMPRLVEGNAPSGTLRADLARELGLDPRVVVAGGGGDNAAS
EHHCCHHHHHHHHHCCCHHHCCHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHH
ALGIGATHAGDGFVSLGTSGVLSIVSDRFTPNPALATHAFCHAIPERWQLMTVVLSAASC
HHCCCCCCCCCCEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRWICTLTGTDEPTLLAEVERLDPGACAQAPLFLPYLSGERTPHNDPYAQGVFFGMTHAT
HHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEHHHHH
ERAHLGYAVLEGVTLGFADGFDALRGIETDALSLIGGGARSQYWAQMIADALNVRTRQHG
HHHHCCHHHHHCCEEECCCCHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
GGETGAALGAARLGWLAVGGDPDTVLAKPPVCAEYAPNAARHAALCERLVAFRELYRHVQ
CCCCHHHHHHHHHCEEEECCCCCCEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHH
PLYEPSRPRLA
HHCCCCCCCCC
>Mature Secondary Structure
MYLGIDLGTSEVKVLLLAPDGTVVGTAGAPFTVSRPHPRWAEQHPEDWWQGTLAALGMLR
CEEEEECCCCCEEEEEECCCCCEEECCCCCEECCCCCCCHHHCCCHHHHHHHHHHHHHHH
ARCPDAFARVRGIGLSGQMHGAVLLDQADRVLRPAILWNDMRSDDECALLTERAPDLHAI
HHCCHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHH
AGNLAMPGFTAPKLLWVARHEPDVFAATTCVLLPKDYLRFRLTGAKVSDPSDAAGTLWLD
HCCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCHHEEEEECCCCCCCCCCCCCEEEEE
VARRDWSDALLAACDLSRDQMPRLVEGNAPSGTLRADLARELGLDPRVVVAGGGGDNAAS
EHHCCHHHHHHHHHCCCHHHCCHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHH
ALGIGATHAGDGFVSLGTSGVLSIVSDRFTPNPALATHAFCHAIPERWQLMTVVLSAASC
HHCCCCCCCCCCEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRWICTLTGTDEPTLLAEVERLDPGACAQAPLFLPYLSGERTPHNDPYAQGVFFGMTHAT
HHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEHHHHH
ERAHLGYAVLEGVTLGFADGFDALRGIETDALSLIGGGARSQYWAQMIADALNVRTRQHG
HHHHCCHHHHHCCEEECCCCHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
GGETGAALGAARLGWLAVGGDPDTVLAKPPVCAEYAPNAARHAALCERLVAFRELYRHVQ
CCCCHHHHHHHHHCEEEECCCCCCEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHH
PLYEPSRPRLA
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]