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The map label for this gene is yngJ [H]

Identifier: 17546739

GI number: 17546739

Start: 2198110

End: 2199372

Strand: Direct

Name: yngJ [H]

Synonym: RSc2020

Alternate gene names: 17546739

Gene position: 2198110-2199372 (Clockwise)

Preceding gene: 17546738

Following gene: 17546740

Centisome position: 59.15

GC content: 69.44

Gene sequence:

>1263_bases
ATGCATTTCGACTACTCGCCCAAGGTCAAGGAGATGCAGGCCCGCCTGCTCGACTTCTTCGACCGGCACATCTATCCGAA
CGAGCACCGCTTCCACGAAGAAGTCGAAGCCAACCGCCGCGCCGGCAACGCCTGGGTCCCGACCCGGGTGATCGAGGCGC
TCAAGCCGCTGGCGCGCGAGGCCGGGCTGTGGAACCTGTTCCTGCCGCGCTCGCCGCGCGCGCCGGAAGGCCTGTCGAAC
CTCGAATACGCGCCGCTGTGCGAGATCATGGGCCGTGTGCCCTGGGCGCCCGAGGTGTTCAACTGTTCCGCGCCGGACAC
CGGCAACATGGAGACGCTGGAGCGCTACGCTTCCGAGGCGCTGAAAGACCGCTGGCTCGAGCCGCTGCTGCGCGGCGAGA
TCCGCTCGGCCTTCCTGATGACCGAGCCGGCCGTGGCCTCGTCGGATGCCACCAACATCGAGTGCCGCATCGAGCGCCAG
GGCGACGACTACGTCATCAACGGACGCAAGTGGTGGTCCTCCGGCGCCGGCGATCCGCGCTGCGCGGTCTACATCGTGAT
GGGCAAGACCAACCCGGATGCGGGCCGCCACGAGCAGCAGTCGATGATCGTGGTGCCGGCCGACGCGCCGGGCATCACCG
TCCTGCGGCCGCTGTCGGTGTTCGGCTACGACGACGCGCCGCACGGCCACATGGAAGTCGATCTGAAGAACGTGCGCGTG
CCGGCCACCAACATCCTGCTGGGCGAGGGACGCGGCTTCGAGATCGCGCAGGGCCGCCTGGGTCCGGGCCGCATCCACCA
CTGCATGCGCAGCATCGGCGTGGCCGAGCGCGCGCTGGAGCTGATGTGCAAGCGCCTGTCGAGCCGCATCGCCTTCGGCA
AGCCGATCGCGCAGCACAGCGTCTGGCACGAGCGCATCGCCGAGGCGCGCTGCATGATCGAGCAGGCGCGCCTGCTCACG
CTCAAGGCCGCGTACATGATGGACACCGTCGGCAACAAGGTCGCCCGCGCCGAGATCGCGATGATCAAGGTGGTGGCGCC
CAACGTCGCCTGCCAGGTCATCGACTGGGCCATCCAGGCGCACGGCGGCGGCGGCGTGTCGGGCGACTTCCCGCTCGCCT
CGGCCTATGCGCACCAGCGCACGCTGCGCCTGGCCGACGGCCCGGACGAGGTGCACCGCGCGGCCATCGCCAAACTGGAA
CTGGCCAAGCACCTGCATCGGCTGGCGGACGTGGTCGACATGCCGATCGCGCGCGGCGCCTGA

Upstream 100 bases:

>100_bases
CGGCGACCGGCTGGTCGCGCGCGCCAGCGCGGTGTTCGCCGTGCTCGGCGCTCGCGTGGCCGGCCCGGTTTGAAGCGCAT
CGATTTTCGGAGGAGACACC

Downstream 100 bases:

>100_bases
GCGGACCGTACCGTTCACTCCTTGGTCCCCGCGTCATGCGGGGATTTTTTTTGCGCGCGCGGGCTGTCTGCGCGTTTTCG
CGTTCTGTGCTTGAATGGGC

Product: acyl-CoA dehydrogenase oxidoreductase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MHFDYSPKVKEMQARLLDFFDRHIYPNEHRFHEEVEANRRAGNAWVPTRVIEALKPLAREAGLWNLFLPRSPRAPEGLSN
LEYAPLCEIMGRVPWAPEVFNCSAPDTGNMETLERYASEALKDRWLEPLLRGEIRSAFLMTEPAVASSDATNIECRIERQ
GDDYVINGRKWWSSGAGDPRCAVYIVMGKTNPDAGRHEQQSMIVVPADAPGITVLRPLSVFGYDDAPHGHMEVDLKNVRV
PATNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELMCKRLSSRIAFGKPIAQHSVWHERIAEARCMIEQARLLT
LKAAYMMDTVGNKVARAEIAMIKVVAPNVACQVIDWAIQAHGGGGVSGDFPLASAYAHQRTLRLADGPDEVHRAAIAKLE
LAKHLHRLADVVDMPIARGA

Sequences:

>Translated_420_residues
MHFDYSPKVKEMQARLLDFFDRHIYPNEHRFHEEVEANRRAGNAWVPTRVIEALKPLAREAGLWNLFLPRSPRAPEGLSN
LEYAPLCEIMGRVPWAPEVFNCSAPDTGNMETLERYASEALKDRWLEPLLRGEIRSAFLMTEPAVASSDATNIECRIERQ
GDDYVINGRKWWSSGAGDPRCAVYIVMGKTNPDAGRHEQQSMIVVPADAPGITVLRPLSVFGYDDAPHGHMEVDLKNVRV
PATNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELMCKRLSSRIAFGKPIAQHSVWHERIAEARCMIEQARLLT
LKAAYMMDTVGNKVARAEIAMIKVVAPNVACQVIDWAIQAHGGGGVSGDFPLASAYAHQRTLRLADGPDEVHRAAIAKLE
LAKHLHRLADVVDMPIARGA
>Mature_420_residues
MHFDYSPKVKEMQARLLDFFDRHIYPNEHRFHEEVEANRRAGNAWVPTRVIEALKPLAREAGLWNLFLPRSPRAPEGLSN
LEYAPLCEIMGRVPWAPEVFNCSAPDTGNMETLERYASEALKDRWLEPLLRGEIRSAFLMTEPAVASSDATNIECRIERQ
GDDYVINGRKWWSSGAGDPRCAVYIVMGKTNPDAGRHEQQSMIVVPADAPGITVLRPLSVFGYDDAPHGHMEVDLKNVRV
PATNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELMCKRLSSRIAFGKPIAQHSVWHERIAEARCMIEQARLLT
LKAAYMMDTVGNKVARAEIAMIKVVAPNVACQVIDWAIQAHGGGGVSGDFPLASAYAHQRTLRLADGPDEVHRAAIAKLE
LAKHLHRLADVVDMPIARGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI38505218, Length=409, Percent_Identity=56.479217603912, Blast_Score=469, Evalue=1e-132,
Organism=Homo sapiens, GI48976061, Length=403, Percent_Identity=57.3200992555831, Blast_Score=457, Evalue=1e-128,
Organism=Homo sapiens, GI211971008, Length=403, Percent_Identity=57.3200992555831, Blast_Score=456, Evalue=1e-128,
Organism=Homo sapiens, GI21361497, Length=389, Percent_Identity=27.7634961439589, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI4557231, Length=413, Percent_Identity=25.4237288135593, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI187960098, Length=413, Percent_Identity=25.4237288135593, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI4501859, Length=322, Percent_Identity=27.9503105590062, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4557233, Length=321, Percent_Identity=28.6604361370716, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI7656849, Length=391, Percent_Identity=25.8312020460358, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI226958412, Length=323, Percent_Identity=26.0061919504644, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI226958414, Length=324, Percent_Identity=25.9259259259259, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI76496475, Length=427, Percent_Identity=26.9320843091335, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI4557235, Length=427, Percent_Identity=26.9320843091335, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4501857, Length=313, Percent_Identity=24.9201277955272, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI87081958, Length=304, Percent_Identity=28.2894736842105, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786223, Length=359, Percent_Identity=22.0055710306407, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562446, Length=365, Percent_Identity=54.5205479452055, Blast_Score=401, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17534899, Length=404, Percent_Identity=26.7326732673267, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17569725, Length=408, Percent_Identity=26.9607843137255, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17570075, Length=289, Percent_Identity=28.3737024221453, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17533517, Length=294, Percent_Identity=28.9115646258503, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI71985184, Length=353, Percent_Identity=27.1954674220963, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=284, Percent_Identity=29.2253521126761, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17505929, Length=295, Percent_Identity=26.4406779661017, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=340, Percent_Identity=26.1764705882353, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17551932, Length=296, Percent_Identity=25.6756756756757, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=382, Percent_Identity=24.0837696335079, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=210, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71985192, Length=257, Percent_Identity=25.6809338521401, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=186, Percent_Identity=27.9569892473118, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24660351, Length=279, Percent_Identity=30.1075268817204, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646207, Length=285, Percent_Identity=29.8245614035088, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI281363737, Length=416, Percent_Identity=25.7211538461538, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21356377, Length=386, Percent_Identity=27.4611398963731, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24666513, Length=288, Percent_Identity=29.5138888888889, Blast_Score=111, Evalue=9e-25,
Organism=Drosophila melanogaster, GI21355753, Length=293, Percent_Identity=25.5972696245734, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 46675; Mature: 46675

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFDYSPKVKEMQARLLDFFDRHIYPNEHRFHEEVEANRRAGNAWVPTRVIEALKPLARE
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AGLWNLFLPRSPRAPEGLSNLEYAPLCEIMGRVPWAPEVFNCSAPDTGNMETLERYASEA
CCCEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHH
LKDRWLEPLLRGEIRSAFLMTEPAVASSDATNIECRIERQGDDYVINGRKWWSSGAGDPR
HHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEECCCCEEECCCEECCCCCCCCC
CAVYIVMGKTNPDAGRHEQQSMIVVPADAPGITVLRPLSVFGYDDAPHGHMEVDLKNVRV
EEEEEEEECCCCCCCCCCCCCEEEEECCCCCCEEEECHHHCCCCCCCCCCEEEECCCEEC
PATNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELMCKRLSSRIAFGKPIAQHS
CHHEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VWHERIAEARCMIEQARLLTLKAAYMMDTVGNKVARAEIAMIKVVAPNVACQVIDWAIQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEEEECCCHHHHHHHHHHEE
HGGGGVSGDFPLASAYAHQRTLRLADGPDEVHRAAIAKLELAKHLHRLADVVDMPIARGA
CCCCCCCCCCCHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHFDYSPKVKEMQARLLDFFDRHIYPNEHRFHEEVEANRRAGNAWVPTRVIEALKPLARE
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AGLWNLFLPRSPRAPEGLSNLEYAPLCEIMGRVPWAPEVFNCSAPDTGNMETLERYASEA
CCCEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHH
LKDRWLEPLLRGEIRSAFLMTEPAVASSDATNIECRIERQGDDYVINGRKWWSSGAGDPR
HHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEECCCCEEECCCEECCCCCCCCC
CAVYIVMGKTNPDAGRHEQQSMIVVPADAPGITVLRPLSVFGYDDAPHGHMEVDLKNVRV
EEEEEEEECCCCCCCCCCCCCEEEEECCCCCCEEEECHHHCCCCCCCCCCEEEECCCEEC
PATNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELMCKRLSSRIAFGKPIAQHS
CHHEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VWHERIAEARCMIEQARLLTLKAAYMMDTVGNKVARAEIAMIKVVAPNVACQVIDWAIQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEEEECCCHHHHHHHHHHEE
HGGGGVSGDFPLASAYAHQRTLRLADGPDEVHRAAIAKLELAKHLHRLADVVDMPIARGA
CCCCCCCCCCCHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]