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The map label for this gene is tcp [H]

Identifier: 17546669

GI number: 17546669

Start: 2126240

End: 2127229

Strand: Direct

Name: tcp [H]

Synonym: RSc1950

Alternate gene names: 17546669

Gene position: 2126240-2127229 (Clockwise)

Preceding gene: 17546665

Following gene: 17546672

Centisome position: 57.21

GC content: 69.6

Gene sequence:

>990_bases
ATGTGTCGGAGCAGGCCCGCGATCGACCGCGTGGAAGCCCGCTACGGCCCCGTGGCCACCGGGATCGTGCAACTGGCGCT
GGACGGCAAGCGCGACGAGGCCATCCAGAAGATGGACGACGAATGCCGTCCGCTGCTGGTCGAGCTGATCCAGGCCACCA
CCGCCTACGCCCGCTATACGCGCGAACGCCAGGAGCAGCTCGTCGCGGCTGACGAAGCGCAGTATGGGCAGCAGCGCAGC
CTGCTGATCGCGCTGTCGATCGCGGCGGTGCTCGTGGCGATCGGGGCGGGCGTGCTGATCACGCGCTCGATCACGCGCCC
CATCGGCAAGGCCGTGAACGTGGCGGAGACGGTGGCCCGCGGCGACCTCGGCAGCCGCATCGACGCCGAAGGCACCGACG
AGACCAGCCACCGGCTCGCCGCGCTCGCCGACATGAACACCCGCCTGACGCAGATCGTCGACAAGGTGCGCGACAGCAGC
GGCAGCATCGCCGGCGCGGCCAGGCCGATCGCGGCGGGCAACGCCGACCTGAGCCAGCGCACCGAAGCGCAGGCCTCCTC
GCTGCAGGAAACCGCCGCCGGCATGGAAGAGCTGACCTCCACCGTAAAGCAGAACGCCGACAATGCCCAGCACGCCACCG
AACTGGCCGCGACGGCGTCGGAGGTGGCGCAGAAGGGCAACGCCGTGGTGAGCCAGGTGGTCTCGACCATGCAGGCCATC
AGCGACCGCTCCGGCAAGATCGCGGAGATCACCAGCATCATCGAGGGGATTGCCTTCCAGACCAACATCCTGGCCCTGAA
CGCCGCGGTGGAAGCCGCCCGCGCGGGCGATCAGGGACGGGGCTTCGCGGTGGTCGCCAACGAGGTGCGCAGCCTCGCGC
AGCGCTCTGCCAAGGCGGCCAAGGAGATCAAGAGGCTGATCGCCTCGTCGGTCGAGCGCATCCACGACAGCTCGACGCTG
GCGACGCGCTACAGCGGATCGCGCAGATAG

Upstream 100 bases:

>100_bases
CCGCAGGACCTGGAGATGGAAAAGGCCGAGGTGCTGCGCGCGCACGAGGAAGTCCAGGCCCAGCTCGCGCAGCTCAAGGC
GATGGCGGACGACGGCCGGA

Downstream 100 bases:

>100_bases
CCGACCAGCCGGTCCACCACCGGCCGGTTCGGCCGGGTCAGCAGGCTGACGATCACGGCGGCGGCAAACCCGGCCGGCAC
GCCGAACGCCCCCGAGGCGA

Product: methyl-accepting chemotaxis transducer transmembrane protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MCRSRPAIDRVEARYGPVATGIVQLALDGKRDEAIQKMDDECRPLLVELIQATTAYARYTRERQEQLVAADEAQYGQQRS
LLIALSIAAVLVAIGAGVLITRSITRPIGKAVNVAETVARGDLGSRIDAEGTDETSHRLAALADMNTRLTQIVDKVRDSS
GSIAGAARPIAAGNADLSQRTEAQASSLQETAAGMEELTSTVKQNADNAQHATELAATASEVAQKGNAVVSQVVSTMQAI
SDRSGKIAEITSIIEGIAFQTNILALNAAVEAARAGDQGRGFAVVANEVRSLAQRSAKAAKEIKRLIASSVERIHDSSTL
ATRYSGSRR

Sequences:

>Translated_329_residues
MCRSRPAIDRVEARYGPVATGIVQLALDGKRDEAIQKMDDECRPLLVELIQATTAYARYTRERQEQLVAADEAQYGQQRS
LLIALSIAAVLVAIGAGVLITRSITRPIGKAVNVAETVARGDLGSRIDAEGTDETSHRLAALADMNTRLTQIVDKVRDSS
GSIAGAARPIAAGNADLSQRTEAQASSLQETAAGMEELTSTVKQNADNAQHATELAATASEVAQKGNAVVSQVVSTMQAI
SDRSGKIAEITSIIEGIAFQTNILALNAAVEAARAGDQGRGFAVVANEVRSLAQRSAKAAKEIKRLIASSVERIHDSSTL
ATRYSGSRR
>Mature_329_residues
MCRSRPAIDRVEARYGPVATGIVQLALDGKRDEAIQKMDDECRPLLVELIQATTAYARYTRERQEQLVAADEAQYGQQRS
LLIALSIAAVLVAIGAGVLITRSITRPIGKAVNVAETVARGDLGSRIDAEGTDETSHRLAALADMNTRLTQIVDKVRDSS
GSIAGAARPIAAGNADLSQRTEAQASSLQETAAGMEELTSTVKQNADNAQHATELAATASEVAQKGNAVVSQVVSTMQAI
SDRSGKIAEITSIIEGIAFQTNILALNAAVEAARAGDQGRGFAVVANEVRSLAQRSAKAAKEIKRLIASSVERIHDSSTL
ATRYSGSRR

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=253, Percent_Identity=51.3833992094862, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1788195, Length=221, Percent_Identity=56.1085972850679, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI1787690, Length=309, Percent_Identity=43.6893203883495, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1788194, Length=254, Percent_Identity=49.6062992125984, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1789453, Length=232, Percent_Identity=39.6551724137931, Blast_Score=153, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 34793; Mature: 34793

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRSRPAIDRVEARYGPVATGIVQLALDGKRDEAIQKMDDECRPLLVELIQATTAYARYT
CCCCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RERQEQLVAADEAQYGQQRSLLIALSIAAVLVAIGAGVLITRSITRPIGKAVNVAETVAR
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
GDLGSRIDAEGTDETSHRLAALADMNTRLTQIVDKVRDSSGSIAGAARPIAAGNADLSQR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
TEAQASSLQETAAGMEELTSTVKQNADNAQHATELAATASEVAQKGNAVVSQVVSTMQAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDRSGKIAEITSIIEGIAFQTNILALNAAVEAARAGDQGRGFAVVANEVRSLAQRSAKAA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
KEIKRLIASSVERIHDSSTLATRYSGSRR
HHHHHHHHHHHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure
MCRSRPAIDRVEARYGPVATGIVQLALDGKRDEAIQKMDDECRPLLVELIQATTAYARYT
CCCCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RERQEQLVAADEAQYGQQRSLLIALSIAAVLVAIGAGVLITRSITRPIGKAVNVAETVAR
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
GDLGSRIDAEGTDETSHRLAALADMNTRLTQIVDKVRDSSGSIAGAARPIAAGNADLSQR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
TEAQASSLQETAAGMEELTSTVKQNADNAQHATELAATASEVAQKGNAVVSQVVSTMQAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDRSGKIAEITSIIEGIAFQTNILALNAAVEAARAGDQGRGFAVVANEVRSLAQRSAKAA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
KEIKRLIASSVERIHDSSTLATRYSGSRR
HHHHHHHHHHHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]