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The map label for this gene is fabZ

Identifier: 17546134

GI number: 17546134

Start: 1515642

End: 1516136

Strand: Direct

Name: fabZ

Synonym: RSc1415

Alternate gene names: 17546134

Gene position: 1515642-1516136 (Clockwise)

Preceding gene: 17546133

Following gene: 17546135

Centisome position: 40.78

GC content: 62.02

Gene sequence:

>495_bases
ATGACCGAACCCTCTGCCGCGACGACGAGCCTCGTCAGCGATTTCAACATCAAGAAGATTCTCGAACTGCTGCCGCACCG
CTATCCGATGCTGCTGGTCGATCGCGTGCTCGAGATGGAGCCGCGCAAGCGCATCAAGGCGATCAAGAACGTCACCTTCA
ACGAGCCGTTCTTCAACGGCCATTTCCCGGGCCACCCGGTGATGCCGGGCGTGCTGATGCTCGAAGCGCTGGCCCAGACC
GCCGCGCTGCTGACCTTCGGCGAGTCCAATCACAAGCGCCAGGAAAACCAGCTCTACCTGTTCGTCAGCATCGATGGCGC
GCGCTTCAAGCGCCAGGTCACGCCGGGCGATCAGCTGGTGCTGAACGCCGAGCTGCTGCGCTCCAAGAGCGGCATGTGGA
AGTTCAAGGTGTTCGCGACCGTGGACGATGAAGTCGCGGCCGAGGCTGAGATCATGTGTGCCGTGCGCGAAGACAAGTCC
AAGGGCGACGCATGA

Upstream 100 bases:

>100_bases
CGGATTGGGAACGTAACGCGGCCATCCTCCGTGGCCTGACGCGCATGCGCGAACGGTTGCAACAACTGGAACAGCAGGTC
AAGCATCTGCAGCAATCATC

Downstream 100 bases:

>100_bases
CGCAAGTTCAGAAGATTCACCCGACCGCGGTGATCGACCCGCAGGCCGAACTGGCCCCGGATGTCGAGGTCGGCGCCTTT
ACCGTGATCGGCCCGAATGT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTEPSAATTSLVSDFNIKKILELLPHRYPMLLVDRVLEMEPRKRIKAIKNVTFNEPFFNGHFPGHPVMPGVLMLEALAQT
AALLTFGESNHKRQENQLYLFVSIDGARFKRQVTPGDQLVLNAELLRSKSGMWKFKVFATVDDEVAAEAEIMCAVREDKS
KGDA

Sequences:

>Translated_164_residues
MTEPSAATTSLVSDFNIKKILELLPHRYPMLLVDRVLEMEPRKRIKAIKNVTFNEPFFNGHFPGHPVMPGVLMLEALAQT
AALLTFGESNHKRQENQLYLFVSIDGARFKRQVTPGDQLVLNAELLRSKSGMWKFKVFATVDDEVAAEAEIMCAVREDKS
KGDA
>Mature_163_residues
TEPSAATTSLVSDFNIKKILELLPHRYPMLLVDRVLEMEPRKRIKAIKNVTFNEPFFNGHFPGHPVMPGVLMLEALAQTA
ALLTFGESNHKRQENQLYLFVSIDGARFKRQVTPGDQLVLNAELLRSKSGMWKFKVFATVDDEVAAEAEIMCAVREDKSK
GDA

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=146, Percent_Identity=50.6849315068493, Blast_Score=157, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_RALSO (Q8XZI0)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_519536.1
- ProteinModelPortal:   Q8XZI0
- SMR:   Q8XZI0
- GeneID:   1220239
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc1415
- NMPDR:   fig|267608.1.peg.1415
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   RSOL267608:RSC1415-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 18462; Mature: 18330

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: ACT_SITE 61-61

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPSAATTSLVSDFNIKKILELLPHRYPMLLVDRVLEMEPRKRIKAIKNVTFNEPFFNG
CCCCCHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCC
HFPGHPVMPGVLMLEALAQTAALLTFGESNHKRQENQLYLFVSIDGARFKRQVTPGDQLV
CCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEEECCHHHEEECCCCCCEE
LNAELLRSKSGMWKFKVFATVDDEVAAEAEIMCAVREDKSKGDA
EEHHHHHCCCCCEEEEEEEECCHHHHHHHHHEEEEECCCCCCCC
>Mature Secondary Structure 
TEPSAATTSLVSDFNIKKILELLPHRYPMLLVDRVLEMEPRKRIKAIKNVTFNEPFFNG
CCCCHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCC
HFPGHPVMPGVLMLEALAQTAALLTFGESNHKRQENQLYLFVSIDGARFKRQVTPGDQLV
CCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEEECCHHHEEECCCCCCEE
LNAELLRSKSGMWKFKVFATVDDEVAAEAEIMCAVREDKSKGDA
EEHHHHHCCCCCEEEEEEEECCHHHHHHHHHEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852