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The map label for this gene is gsiD [H]

Identifier: 17546101

GI number: 17546101

Start: 1474053

End: 1474952

Strand: Direct

Name: gsiD [H]

Synonym: RSc1382

Alternate gene names: 17546101

Gene position: 1474053-1474952 (Clockwise)

Preceding gene: 17546100

Following gene: 17546102

Centisome position: 39.66

GC content: 67.89

Gene sequence:

>900_bases
ATGACACAGGCATCCAGCCCGGCGGTGATCCCGCAGGCCGCCAGCGAACCCGTCCGCACGCCCTGGAGCGAGTTCTGGCG
CAAGTTCCGCAAGCAGCATCTGGCACTCGGCGCCGGCGTGTTCGTGATCGCGCTGGTGGTGGCGGCGATCCTGGCGCCGC
ACCTGGTGCCGTTCGATCCGGAAAACTATTTCGACTATGACGCGCTCAACGCCGGGCCGTCCGCCGCGCACTGGTTCGGC
GTCGATTCGCTCGGCCGCGACATCTTCAGCCGCATCCTGATGGGCACGCGGATCTCGCTGGAGGCCGGCTTCGTGTCGGT
CGTCATCGGCGCCCTCATCGGGACGGTGCTCGGCCTGCTCGCCGGCTACTACGAAGGCTGGTGGGACCGCATCGTCATGC
GCATCTGCGATGTGCTGTTCGCCTTTCCCGGCATCCTGCTGGCGATCGGCATCGTGGCGATCCTGGGCAACGGCATGGCC
AACGTGATCTTCGCCGTGGCGGTGTTCAGCGTTCCGGCCTTCGCGCGGCTGGTGCGCGGCAACACGCTGATGCTCAAGCA
CCTGACCTACGTCGAGGCCGCGCGCAGCATCGGCGCGTCGGACCGGACCATCCTGCTGCGCCACATCCTGCCGGGCACCA
TCTCGTCCATCGTGGTGTATTTCTCGATGCGGATCGGCACCTCGATCATCACCGCCGCGAGCCTGTCGTTCCTGGGCCTG
GGCGCGCAGCCGCCGACGCCGGAGTGGGGCGCGATGCTCAACGAGGCGCGCGCCGACATGGTGACCGCGCCGCATGTGGC
GATCTTCCCGAGCCTCGCCATCTTCCTGACCGTGCTGGCGTTCAACCTGCTGGGCGATGGCCTGCGGGATGCGCTCGACC
CCAAGATCGACCGCCGCTGA

Upstream 100 bases:

>100_bases
CTGCTGTTCTCGCTGGAGTTCATCTTGATCAACCTGGTGGTGGACATTCTGTACACCGTGATCAACCCGACCATCCGCTA
CGCGAAATAAGGAGTCCGCC

Downstream 100 bases:

>100_bases
CATGACCCACAGCATGGCCCACATCGGCGTGCTGCCGGCTGGCGCGCGCAACAGCATCACGGACGTGGCCGGCATCACGG
TCGGGCACGCCACGCTCGCC

Product: transmembrane ABC transporter protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTQASSPAVIPQAASEPVRTPWSEFWRKFRKQHLALGAGVFVIALVVAAILAPHLVPFDPENYFDYDALNAGPSAAHWFG
VDSLGRDIFSRILMGTRISLEAGFVSVVIGALIGTVLGLLAGYYEGWWDRIVMRICDVLFAFPGILLAIGIVAILGNGMA
NVIFAVAVFSVPAFARLVRGNTLMLKHLTYVEAARSIGASDRTILLRHILPGTISSIVVYFSMRIGTSIITAASLSFLGL
GAQPPTPEWGAMLNEARADMVTAPHVAIFPSLAIFLTVLAFNLLGDGLRDALDPKIDRR

Sequences:

>Translated_299_residues
MTQASSPAVIPQAASEPVRTPWSEFWRKFRKQHLALGAGVFVIALVVAAILAPHLVPFDPENYFDYDALNAGPSAAHWFG
VDSLGRDIFSRILMGTRISLEAGFVSVVIGALIGTVLGLLAGYYEGWWDRIVMRICDVLFAFPGILLAIGIVAILGNGMA
NVIFAVAVFSVPAFARLVRGNTLMLKHLTYVEAARSIGASDRTILLRHILPGTISSIVVYFSMRIGTSIITAASLSFLGL
GAQPPTPEWGAMLNEARADMVTAPHVAIFPSLAIFLTVLAFNLLGDGLRDALDPKIDRR
>Mature_298_residues
TQASSPAVIPQAASEPVRTPWSEFWRKFRKQHLALGAGVFVIALVVAAILAPHLVPFDPENYFDYDALNAGPSAAHWFGV
DSLGRDIFSRILMGTRISLEAGFVSVVIGALIGTVLGLLAGYYEGWWDRIVMRICDVLFAFPGILLAIGIVAILGNGMAN
VIFAVAVFSVPAFARLVRGNTLMLKHLTYVEAARSIGASDRTILLRHILPGTISSIVVYFSMRIGTSIITAASLSFLGLG
AQPPTPEWGAMLNEARADMVTAPHVAIFPSLAIFLTVLAFNLLGDGLRDALDPKIDRR

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=288, Percent_Identity=77.0833333333333, Blast_Score=462, Evalue=1e-132,
Organism=Escherichia coli, GI1787760, Length=295, Percent_Identity=39.3220338983051, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1789964, Length=305, Percent_Identity=41.6393442622951, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1789889, Length=241, Percent_Identity=39.4190871369295, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI1787498, Length=282, Percent_Identity=36.5248226950355, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1787549, Length=272, Percent_Identity=34.1911764705882, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1788505, Length=225, Percent_Identity=32.8888888888889, Blast_Score=121, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32202; Mature: 32071

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQASSPAVIPQAASEPVRTPWSEFWRKFRKQHLALGAGVFVIALVVAAILAPHLVPFDP
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ENYFDYDALNAGPSAAHWFGVDSLGRDIFSRILMGTRISLEAGFVSVVIGALIGTVLGLL
CCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AGYYEGWWDRIVMRICDVLFAFPGILLAIGIVAILGNGMANVIFAVAVFSVPAFARLVRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
NTLMLKHLTYVEAARSIGASDRTILLRHILPGTISSIVVYFSMRIGTSIITAASLSFLGL
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAQPPTPEWGAMLNEARADMVTAPHVAIFPSLAIFLTVLAFNLLGDGLRDALDPKIDRR
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TQASSPAVIPQAASEPVRTPWSEFWRKFRKQHLALGAGVFVIALVVAAILAPHLVPFDP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ENYFDYDALNAGPSAAHWFGVDSLGRDIFSRILMGTRISLEAGFVSVVIGALIGTVLGLL
CCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AGYYEGWWDRIVMRICDVLFAFPGILLAIGIVAILGNGMANVIFAVAVFSVPAFARLVRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
NTLMLKHLTYVEAARSIGASDRTILLRHILPGTISSIVVYFSMRIGTSIITAASLSFLGL
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAQPPTPEWGAMLNEARADMVTAPHVAIFPSLAIFLTVLAFNLLGDGLRDALDPKIDRR
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]