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The map label for this gene is gsiC [H]

Identifier: 17546100

GI number: 17546100

Start: 1473119

End: 1474042

Strand: Direct

Name: gsiC [H]

Synonym: RSc1381

Alternate gene names: 17546100

Gene position: 1473119-1474042 (Clockwise)

Preceding gene: 17546099

Following gene: 17546101

Centisome position: 39.64

GC content: 65.04

Gene sequence:

>924_bases
ATGCTGAATTACTTCCTCAAACGTGTGCTGGGCGTGATCCCGACGCTGCTGATCGTGGCGGTGCTGGTGTTCCTGTTCGT
GCACCTGCTGCCGGGCGATCCGGCGCGCCTGGCCGCCGGTACCGACGCCGACGAAGCGACCGTCGAACTGGTGCGTAAGG
ACCTGGGCCTGGACAAGCCGATGCACGAGCAGTTCGTGCACTTCTTCGCCAATGCCGTGCGCGGCGAGTTCGGTGCGTCG
CTACGGACCAAGCGCCCGGTGAGCGAGGAGATCGGCGACCGCTTCATGCCCACGCTCAATCTGACGATTGCCAGCATGGT
GTGGGCCGTGATCTTCGGCATGGCCATCGGCATCGTCTCCGCCGTCTGGCGCAACAAGTGGCCGGACCGCCTGGGCATGA
CGCTGGCGGTCTCGGGTATTTCGTTTCCCGCCTTCGCGCTGGGCATGCTGCTGATGGAGGTGTTCTCCGTGCAGCTCGGC
TGGCTGCCCTCGATCGGGGCCGACAGCTGGAAGCACTACATCCTGCCGTCGCTGACGCTGGGCGCCGCCGTGGCCGCGGT
GATGGCGCGCTTCACGCGGGCATCGTTCGTCGAGGTGCTGCAGGAAGACTTCGTGCGCACCGCCCGCGCCAAGGGCGTGC
GCGAGACCGTGGTGGTCGCCAAGCATTGCCTGCGCAACGCGATGATCCCGGTGGTGACCATGATGGGCCTGCAGTTCGGC
TTTCTGCTGGGCGGCTCGATCGTGGTGGAGAAGGTGTTCAACTGGCCGGGCCTGGGGCGCCTGCTGGTGGACGCGGTGGA
GATGCGCGACTACCCCGTCATCCAGGCCGAGGTGCTGCTGTTCTCGCTGGAGTTCATCTTGATCAACCTGGTGGTGGACA
TTCTGTACACCGTGATCAACCCGACCATCCGCTACGCGAAATAA

Upstream 100 bases:

>100_bases
TCGTTCAGCTTCGACGACATCGATATCAAGCAGTGACGCCGTACCGGCCCGCGCACGCAGCCTGCGCGCGGGCCGGGAAT
TTCCGCCCGTGGTGGATGCC

Downstream 100 bases:

>100_bases
GGAGTCCGCCATGACACAGGCATCCAGCCCGGCGGTGATCCCGCAGGCCGCCAGCGAACCCGTCCGCACGCCCTGGAGCG
AGTTCTGGCGCAAGTTCCGC

Product: transmembrane ABC transporter protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MLNYFLKRVLGVIPTLLIVAVLVFLFVHLLPGDPARLAAGTDADEATVELVRKDLGLDKPMHEQFVHFFANAVRGEFGAS
LRTKRPVSEEIGDRFMPTLNLTIASMVWAVIFGMAIGIVSAVWRNKWPDRLGMTLAVSGISFPAFALGMLLMEVFSVQLG
WLPSIGADSWKHYILPSLTLGAAVAAVMARFTRASFVEVLQEDFVRTARAKGVRETVVVAKHCLRNAMIPVVTMMGLQFG
FLLGGSIVVEKVFNWPGLGRLLVDAVEMRDYPVIQAEVLLFSLEFILINLVVDILYTVINPTIRYAK

Sequences:

>Translated_307_residues
MLNYFLKRVLGVIPTLLIVAVLVFLFVHLLPGDPARLAAGTDADEATVELVRKDLGLDKPMHEQFVHFFANAVRGEFGAS
LRTKRPVSEEIGDRFMPTLNLTIASMVWAVIFGMAIGIVSAVWRNKWPDRLGMTLAVSGISFPAFALGMLLMEVFSVQLG
WLPSIGADSWKHYILPSLTLGAAVAAVMARFTRASFVEVLQEDFVRTARAKGVRETVVVAKHCLRNAMIPVVTMMGLQFG
FLLGGSIVVEKVFNWPGLGRLLVDAVEMRDYPVIQAEVLLFSLEFILINLVVDILYTVINPTIRYAK
>Mature_307_residues
MLNYFLKRVLGVIPTLLIVAVLVFLFVHLLPGDPARLAAGTDADEATVELVRKDLGLDKPMHEQFVHFFANAVRGEFGAS
LRTKRPVSEEIGDRFMPTLNLTIASMVWAVIFGMAIGIVSAVWRNKWPDRLGMTLAVSGISFPAFALGMLLMEVFSVQLG
WLPSIGADSWKHYILPSLTLGAAVAAVMARFTRASFVEVLQEDFVRTARAKGVRETVVVAKHCLRNAMIPVVTMMGLQFG
FLLGGSIVVEKVFNWPGLGRLLVDAVEMRDYPVIQAEVLLFSLEFILINLVVDILYTVINPTIRYAK

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=305, Percent_Identity=79.344262295082, Blast_Score=505, Evalue=1e-144,
Organism=Escherichia coli, GI1789965, Length=340, Percent_Identity=41.4705882352941, Blast_Score=257, Evalue=6e-70,
Organism=Escherichia coli, GI1789888, Length=308, Percent_Identity=37.3376623376623, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787761, Length=326, Percent_Identity=38.6503067484663, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1787497, Length=309, Percent_Identity=34.9514563106796, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787550, Length=270, Percent_Identity=31.8518518518519, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1788504, Length=362, Percent_Identity=27.3480662983425, Blast_Score=124, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33949; Mature: 33949

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYFLKRVLGVIPTLLIVAVLVFLFVHLLPGDPARLAAGTDADEATVELVRKDLGLDKP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCC
MHEQFVHFFANAVRGEFGASLRTKRPVSEEIGDRFMPTLNLTIASMVWAVIFGMAIGIVS
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AVWRNKWPDRLGMTLAVSGISFPAFALGMLLMEVFSVQLGWLPSIGADSWKHYILPSLTL
HHHHCCCCHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHH
GAAVAAVMARFTRASFVEVLQEDFVRTARAKGVRETVVVAKHCLRNAMIPVVTMMGLQFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGGSIVVEKVFNWPGLGRLLVDAVEMRDYPVIQAEVLLFSLEFILINLVVDILYTVIN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTIRYAK
CHHHCCC
>Mature Secondary Structure
MLNYFLKRVLGVIPTLLIVAVLVFLFVHLLPGDPARLAAGTDADEATVELVRKDLGLDKP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCC
MHEQFVHFFANAVRGEFGASLRTKRPVSEEIGDRFMPTLNLTIASMVWAVIFGMAIGIVS
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AVWRNKWPDRLGMTLAVSGISFPAFALGMLLMEVFSVQLGWLPSIGADSWKHYILPSLTL
HHHHCCCCHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHH
GAAVAAVMARFTRASFVEVLQEDFVRTARAKGVRETVVVAKHCLRNAMIPVVTMMGLQFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGGSIVVEKVFNWPGLGRLLVDAVEMRDYPVIQAEVLLFSLEFILINLVVDILYTVIN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTIRYAK
CHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA