Click here to switch to the map view.

The map label for this gene is tcp [H]

Identifier: 17545953

GI number: 17545953

Start: 1306376

End: 1307920

Strand: Direct

Name: tcp [H]

Synonym: RSc1234

Alternate gene names: 17545953

Gene position: 1306376-1307920 (Clockwise)

Preceding gene: 17545952

Following gene: 17545960

Centisome position: 35.15

GC content: 70.29

Gene sequence:

>1545_bases
ATGAAACTCGCGATCAAGCTTCCCCTGGCCTTTGCCGCAGCGCTGCTGCTGATGTTTGCCGGGGCGATCTACGGCATTGT
GTCCCTCAACGGGTCGATCACCGAATACAACACCACGGTCCAGGCGCGCGTGGCCGACGAGCGCGCGGTGACCAGCATGC
TGGTCAACTTCAAGACCCAGGTGCAGGAGTGGAAGGACACGCTGCTGCGCGGCAAGGTCCAGGCCACGCGCGACAAGCAC
TGGGCCGCCTTCGGCCAGCGCGAGCAGGACGTCGCCGGGCAGGCCCGGGCGCTGCAGGCGTCGCTGCCGCCGGGCAAGAG
CCGTGATCTGGTCGGCCAGTTCGCGGCCGCCCACGCGACGATGGGACAGGGCTATCGGAAGGGCTACGAGTCCTTCGTTG
CGGCGGCGTTCGATCCGACGGTGGGCGATCAGGTGGTGACCGGGGTGGACCGCGAGCCGTCGAGGCTGCTCGACGAGGCG
GCGCGTGAGATCGCGGCGGAAAGCGCCGCGGTGTCGGCCCGGACGGCGGCGACGGCGCACACGGTACTGGTGGTCAGCGT
CGTGCTGATGCTGGTGGCGTTCGGGTTGGGCCTGGCCGGTGCGTTCCTGTTCAGCCGCTCGATCACGCGGCCGCTGTCGC
GCGCGGTCGAGGTGGCGCGCACGGTGGCGCAGGGCGATCTGGGGAGCGCGTTCGAGGCGCGCGGCTCCGACGAGATCGCG
CAACTGCTGATCGCGCTCAGGGAGATGCAGGGCAGCCTGGCCAAGGTGGTGAGCGAGGTGCGGCGCAATGCAGAAGGCGT
GGCCTCGGCCAGTGCGCAGATCGCTTCGGGCAACCTGAACCTGTCGTCGCGCACCGAGGAGCAGGCGGCCTCGCTGGAGG
AGACCGCCGCCAACATGGGCGAGCTGACCTCGACCGTGCGCCTCAATTCCGAGAATGCCGTGCAGGCGTCGACGCTGGCC
GGCCACGCCTCCGATACGGCGGCGCGCGGCGGCAAGGTGATGACCGACGTGGTCGAGACCATGCAGGGCATTTCGGAGAG
CTCGGCCAAGGTGGGCGAGATCATCGGCGTGATCGACAGCATTGCGTTCCAGACCAACATCCTCGCGCTCAACGCGGCGG
TCGAGGCCGCGCGTGCCGGCGAGCAGGGGCGCGGGTTTGCGGTGGTGGCGGGCGAGGTGCGCACGCTGGCGCAGCGCAGC
GCCTCGGCGGCCAAGGAGATCAAGGGCCTGATCGGCCAGTCGGCCGAGCGGGTGGAAGCCGGCGCGCGGCTGGTGCAGGA
GGCCGGCGGCATCATCGACGAGATCGTGGCCTCCGTGCAGCGCGTGACGCAGATCGTGTCGGAGATCTCGTCGGCCTCGG
CCGAGCAGAGCACCGGTATCGAGCAGGTGAACATCGCCGTCGGGCAGATCGAGGAAGTGACGCAGCAGAACGCCGCGCTG
GTGGAAGAGGCCTCGGCCGCGGCGCAGCAGATGGCCGACCAGGCCGACGCGCTGCGCCGCGCGGTGGCGATCTTCCGGGT
GGACGGCGAGGCCGGGCGGGCATAG

Upstream 100 bases:

>100_bases
AAGACGTCGCCCGGCACGCGGCGCCGGCATCACGCCCTGACGAGGAGGCGGAAGCGGGCCCGCGCGTGCCGATGCAGACA
GTCGTCTCTACGGAATCCCC

Downstream 100 bases:

>100_bases
CGGGCATCGCGCATCGTGTGCATAGGGTGCATATCGCGCCCAAAGAAAAAGCCGTTCAGCGCAAACTGAACGGCTTTTTT
GTGCCCCGCGCGTGGACGGG

Product: methyl-accepting chemotaxis transmembrane protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MKLAIKLPLAFAAALLLMFAGAIYGIVSLNGSITEYNTTVQARVADERAVTSMLVNFKTQVQEWKDTLLRGKVQATRDKH
WAAFGQREQDVAGQARALQASLPPGKSRDLVGQFAAAHATMGQGYRKGYESFVAAAFDPTVGDQVVTGVDREPSRLLDEA
AREIAAESAAVSARTAATAHTVLVVSVVLMLVAFGLGLAGAFLFSRSITRPLSRAVEVARTVAQGDLGSAFEARGSDEIA
QLLIALREMQGSLAKVVSEVRRNAEGVASASAQIASGNLNLSSRTEEQAASLEETAANMGELTSTVRLNSENAVQASTLA
GHASDTAARGGKVMTDVVETMQGISESSAKVGEIIGVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRS
ASAAKEIKGLIGQSAERVEAGARLVQEAGGIIDEIVASVQRVTQIVSEISSASAEQSTGIEQVNIAVGQIEEVTQQNAAL
VEEASAAAQQMADQADALRRAVAIFRVDGEAGRA

Sequences:

>Translated_514_residues
MKLAIKLPLAFAAALLLMFAGAIYGIVSLNGSITEYNTTVQARVADERAVTSMLVNFKTQVQEWKDTLLRGKVQATRDKH
WAAFGQREQDVAGQARALQASLPPGKSRDLVGQFAAAHATMGQGYRKGYESFVAAAFDPTVGDQVVTGVDREPSRLLDEA
AREIAAESAAVSARTAATAHTVLVVSVVLMLVAFGLGLAGAFLFSRSITRPLSRAVEVARTVAQGDLGSAFEARGSDEIA
QLLIALREMQGSLAKVVSEVRRNAEGVASASAQIASGNLNLSSRTEEQAASLEETAANMGELTSTVRLNSENAVQASTLA
GHASDTAARGGKVMTDVVETMQGISESSAKVGEIIGVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRS
ASAAKEIKGLIGQSAERVEAGARLVQEAGGIIDEIVASVQRVTQIVSEISSASAEQSTGIEQVNIAVGQIEEVTQQNAAL
VEEASAAAQQMADQADALRRAVAIFRVDGEAGRA
>Mature_514_residues
MKLAIKLPLAFAAALLLMFAGAIYGIVSLNGSITEYNTTVQARVADERAVTSMLVNFKTQVQEWKDTLLRGKVQATRDKH
WAAFGQREQDVAGQARALQASLPPGKSRDLVGQFAAAHATMGQGYRKGYESFVAAAFDPTVGDQVVTGVDREPSRLLDEA
AREIAAESAAVSARTAATAHTVLVVSVVLMLVAFGLGLAGAFLFSRSITRPLSRAVEVARTVAQGDLGSAFEARGSDEIA
QLLIALREMQGSLAKVVSEVRRNAEGVASASAQIASGNLNLSSRTEEQAASLEETAANMGELTSTVRLNSENAVQASTLA
GHASDTAARGGKVMTDVVETMQGISESSAKVGEIIGVIDSIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRS
ASAAKEIKGLIGQSAERVEAGARLVQEAGGIIDEIVASVQRVTQIVSEISSASAEQSTGIEQVNIAVGQIEEVTQQNAAL
VEEASAAAQQMADQADALRRAVAIFRVDGEAGRA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=372, Percent_Identity=52.9569892473118, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1788194, Length=371, Percent_Identity=48.5175202156334, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI1787690, Length=325, Percent_Identity=51.6923076923077, Blast_Score=285, Evalue=5e-78,
Organism=Escherichia coli, GI1788195, Length=302, Percent_Identity=54.635761589404, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1789453, Length=320, Percent_Identity=39.6875, Blast_Score=215, Evalue=6e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 53546; Mature: 53546

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAIKLPLAFAAALLLMFAGAIYGIVSLNGSITEYNTTVQARVADERAVTSMLVNFKTQ
CCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHH
VQEWKDTLLRGKVQATRDKHWAAFGQREQDVAGQARALQASLPPGKSRDLVGQFAAAHAT
HHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
MGQGYRKGYESFVAAAFDPTVGDQVVTGVDREPSRLLDEAAREIAAESAAVSARTAATAH
HHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVLVVSVVLMLVAFGLGLAGAFLFSRSITRPLSRAVEVARTVAQGDLGSAFEARGSDEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHH
QLLIALREMQGSLAKVVSEVRRNAEGVASASAQIASGNLNLSSRTEEQAASLEETAANMG
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
ELTSTVRLNSENAVQASTLAGHASDTAARGGKVMTDVVETMQGISESSAKVGEIIGVIDS
HHHHHEEECCCCCHHHHHHCCCCCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSASAAKEIKGLIGQSAERVEA
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GARLVQEAGGIIDEIVASVQRVTQIVSEISSASAEQSTGIEQVNIAVGQIEEVTQQNAAL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
VEEASAAAQQMADQADALRRAVAIFRVDGEAGRA
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCC
>Mature Secondary Structure
MKLAIKLPLAFAAALLLMFAGAIYGIVSLNGSITEYNTTVQARVADERAVTSMLVNFKTQ
CCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHH
VQEWKDTLLRGKVQATRDKHWAAFGQREQDVAGQARALQASLPPGKSRDLVGQFAAAHAT
HHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
MGQGYRKGYESFVAAAFDPTVGDQVVTGVDREPSRLLDEAAREIAAESAAVSARTAATAH
HHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVLVVSVVLMLVAFGLGLAGAFLFSRSITRPLSRAVEVARTVAQGDLGSAFEARGSDEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHH
QLLIALREMQGSLAKVVSEVRRNAEGVASASAQIASGNLNLSSRTEEQAASLEETAANMG
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
ELTSTVRLNSENAVQASTLAGHASDTAARGGKVMTDVVETMQGISESSAKVGEIIGVIDS
HHHHHEEECCCCCHHHHHHCCCCCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSASAAKEIKGLIGQSAERVEA
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GARLVQEAGGIIDEIVASVQRVTQIVSEISSASAEQSTGIEQVNIAVGQIEEVTQQNAAL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
VEEASAAAQQMADQADALRRAVAIFRVDGEAGRA
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]