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The map label for this gene is queC [H]

Identifier: 17545457

GI number: 17545457

Start: 784520

End: 785194

Strand: Direct

Name: queC [H]

Synonym: RSc0738

Alternate gene names: 17545457

Gene position: 784520-785194 (Clockwise)

Preceding gene: 17545456

Following gene: 17545458

Centisome position: 21.11

GC content: 68.59

Gene sequence:

>675_bases
ATGAAAAAACGCGCCATCGTCCTGCTGTCCGGCGGGCTGGATTCCGCCACCGTGCTCGCCATGGCCAACGCGCAGGGCTT
CGAGACCTACGCGCTGTCGATGCGCTACGGTCAGCGTCATTCTTCCGAGCTGGAGGCGGCCAAGAAGGTGGCCGCCGCGC
TGGGGGCCGTCCGCCATGAGATCGTCGATCTGGACCTGCGCCGCTTCGGTGGTTCCGCGCTCACCGATGATGCGCTCGAA
GTGCCGACCACGGGCGTGCAGGAGGGGATCCCCATCACCTACGTGCCGGCGCGCAACACCATCATGCTGTCGCTGGCGCT
GGGCTGGGCGGAGGCTGTCGGGGCACGCGACCTGTTCTTCGGCGCCAATGCCGTCGACTATTCCGGCTACCCCGACTGCC
GCCCCGAGTACGTCGCCGCCTACGAGACGCTGGCGAACCTGGCCACGAAGGCCGGCGTGGAAGGCGATCACATCCGCGTC
AATGCGCCGATCATCGCCATGACCAAGGCCGAGATCATCCAGGCCGGCGCACGGCTGGGCGTCGACTACAGCCTGACCGT
GTCGTGCTACCAGGCCGACGATGAGGGCCGCGCGTGCGGCGTCTGCGATTCGTGCCGCATCCGCCGTGCCGGCTTCGAGG
CGGCGGCGGTGCCGGACCCGACGCGCTATCGCTGA

Upstream 100 bases:

>100_bases
GCGGCCGGAATGCCCGTCATGGCCGGCAGTCGGAGCCCGCGGCGTACCGGCGCGCTAAAATGCGGGCCTTCCACCGATTG
TTTCCCCAGGGCTTTCCCCC

Downstream 100 bases:

>100_bases
TCCCGGGAGTGCTATCCGATGCCAGACATTGATCTTCACGCGCTGTCCCGCACCGTGCTGTGGGCGACGTTCGCCCTGAC
GTTTCTGTTCGGCGCGATCC

Product: signal peptide protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKKRAIVLLSGGLDSATVLAMANAQGFETYALSMRYGQRHSSELEAAKKVAAALGAVRHEIVDLDLRRFGGSALTDDALE
VPTTGVQEGIPITYVPARNTIMLSLALGWAEAVGARDLFFGANAVDYSGYPDCRPEYVAAYETLANLATKAGVEGDHIRV
NAPIIAMTKAEIIQAGARLGVDYSLTVSCYQADDEGRACGVCDSCRIRRAGFEAAAVPDPTRYR

Sequences:

>Translated_224_residues
MKKRAIVLLSGGLDSATVLAMANAQGFETYALSMRYGQRHSSELEAAKKVAAALGAVRHEIVDLDLRRFGGSALTDDALE
VPTTGVQEGIPITYVPARNTIMLSLALGWAEAVGARDLFFGANAVDYSGYPDCRPEYVAAYETLANLATKAGVEGDHIRV
NAPIIAMTKAEIIQAGARLGVDYSLTVSCYQADDEGRACGVCDSCRIRRAGFEAAAVPDPTRYR
>Mature_224_residues
MKKRAIVLLSGGLDSATVLAMANAQGFETYALSMRYGQRHSSELEAAKKVAAALGAVRHEIVDLDLRRFGGSALTDDALE
VPTTGVQEGIPITYVPARNTIMLSLALGWAEAVGARDLFFGANAVDYSGYPDCRPEYVAAYETLANLATKAGVEGDHIRV
NAPIIAMTKAEIIQAGARLGVDYSLTVSCYQADDEGRACGVCDSCRIRRAGFEAAAVPDPTRYR

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=224, Percent_Identity=37.0535714285714, Blast_Score=134, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 23879; Mature: 23879

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRAIVLLSGGLDSATVLAMANAQGFETYALSMRYGQRHSSELEAAKKVAAALGAVRHE
CCCEEEEEEECCCCCEEEEEEECCCCCEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHH
IVDLDLRRFGGSALTDDALEVPTTGVQEGIPITYVPARNTIMLSLALGWAEAVGARDLFF
HHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCEEEECCCCEEEEEEEHHHHHHCCCCCEEE
GANAVDYSGYPDCRPEYVAAYETLANLATKAGVEGDHIRVNAPIIAMTKAEIIQAGARLG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEHHHHHHHHHHHCC
VDYSLTVSCYQADDEGRACGVCDSCRIRRAGFEAAAVPDPTRYR
CCEEEEEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKRAIVLLSGGLDSATVLAMANAQGFETYALSMRYGQRHSSELEAAKKVAAALGAVRHE
CCCEEEEEEECCCCCEEEEEEECCCCCEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHH
IVDLDLRRFGGSALTDDALEVPTTGVQEGIPITYVPARNTIMLSLALGWAEAVGARDLFF
HHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCEEEECCCCEEEEEEEHHHHHHCCCCCEEE
GANAVDYSGYPDCRPEYVAAYETLANLATKAGVEGDHIRVNAPIIAMTKAEIIQAGARLG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEHHHHHHHHHHHCC
VDYSLTVSCYQADDEGRACGVCDSCRIRRAGFEAAAVPDPTRYR
CCEEEEEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA