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The map label for this gene is lptD

Identifier: 17545234

GI number: 17545234

Start: 551121

End: 553556

Strand: Direct

Name: lptD

Synonym: RSc0515

Alternate gene names: 17545234

Gene position: 551121-553556 (Clockwise)

Preceding gene: 17545229

Following gene: 17545235

Centisome position: 14.83

GC content: 66.63

Gene sequence:

>2436_bases
ATGACCGAACCGAACCGAGCCAGGAAAACCCGGCAGCGCACCGCTTTTGCTGCGCCCGATCAGCGGACCGCACCCCGTCG
TGGCGCGCTGGCGCTGCGGCCGCTGGTGTTCGCGGTGGCCGGGGTCTGGACGGCGGCATCCGCGGCGCAGAGTCAGGGCG
CCACGCAGCAGGCGGCGTCCGCGCAGGCACCCTCGTCGGCCGCTTCCGTGACGGCCCTGGCGGTGTCGGGCCCGACCACG
CCGGGCGGCGCACCGCTGGTGCCCAAGATGGCCGAGCCCGTCAAGCGCCCGGACAACGCCGTGCCCTCGTTTGCCGCCGC
CGATGCCATGGACGGCCGCACCAATGAGGACATCCACCTGCGCGGCCACGGCGAGCTGCGCCGCAACGGCACCGTGGTCA
AGGGCGACACGCTGGACTACAACCAGGACACCGATTTCGCCACCGCCACCGGCAACGTGCGCCTGTTCCGCGACGGCACG
CTCGTCACCGGCCCGGACGCCGCGCTCAAGGTGACCGCCAACGAGGGCACCATGCACACGCCCTCGTACGAATTCCACAC
CGTGGGCGGCCGCGGCAGCGCCGAGCGCATCGATTTCATCGACAAGGACAACAGCCGCATCACCAAGGGCACGTACACCA
CGTGTTCGCCGGACAACGTCGACTGGTACTTCAGCGCCAGCCAGATCGACATCGACAGCGACCGCCAGGTCGGCTCCGGC
CGCGCTGGTGTGCTGCACTTCCTGGGCATGCCGGTGTTCGCCTCGCCGGTGTTCGATTTCCCGCTCAACGATGAGCGCCG
CAGCGGCTTTCTCGCGCCGGTGTTCGGCTACAGCAGCCGCAGCGGCGCCGACGTGACGCTGCCGTACTACTTCAACATCG
CGCCCAACCGGGACCTGACGCTGTATCCGCGTCTGCTCTCGCAGCGCGGCCTGCAGTTGGGCGCCGAGTATCGCTACCTG
AGCCAGACCTACAACGGCGTGCTGCGCGGCGAATTCCTGCCCAATGATCGCGAGGCCGACCGCAACCGCTGGTCGATCGC
GCTGGTGCACAACCAGCGTCTGGCGACCGGCCTGAACGCCTACGTCAACTACAACAAGGTCTCCGACAGCACCTACCCGG
ACGACCTCGGCCGCAGCATCGTCACGGCGACGCAGCGCCAGTACACGCAGGAAGGCGGCGTCACGTATTCCATCGGCGAC
TGGGTGGCCCTGGCGCGGGTGCAGAAGTTCCAGACGCTGTCGACCGCGACCACGGCGCTGTCGCCGCCGTACGAGCGCGT
GCCGCAGCTGAACCTGTCGTACAACCGGTACGATGTCGGCGGCTTCGACATCAACTTCCAGACCGACTACACCAAGTTCA
GCATCCCGACCGAGAACACGGTCCAGGGCGAGCGCCTGTTCATGCAGCCGACGATCAGCTATCCGATCATCCGGCCGGGC
TGGTTCGTCACGCCCAAGTTCATCCTGAACACGACGTCGTACCGCCTGGACCGCCCGACGGGCGACACGCAGGCTTCGCA
GATCAACCGCACGCTGCCGACCGTCTCGCTCGATTCGGGGCTGACCTTCGAGCGCGATACGCCGCTGGTGTCGAAGTGGT
TCGGCCGCAGCTACATCCAGACGCTGGAGCCGCGGCTGTTCTACGTCTACACGCCGTTCCGCGACCAGTCGCAGATCCCG
CTGTTCGATACGGCGCAGTCGGACTACAACCTCGGCCAGATCTTCACCGAGAACCCGTACACCGGCTACGACCGCATCGC
CGACAACAACAAGCTGACGGCCGGCGTGACCACCCGCTTCATCGAGTCCGAGACGGGCATCGAGCGCCTGCGCGCCACGC
TGGCCCAGCGCCTGGACTTCGAGGGCCAGCGCGTGACCCTGGCCGGCTCGGCGCCCACCTCGGTGCGCCGCTATTCGGAC
CTGTTGGGCGCGACCACCATCCAGATGTTCCGCGGTATCTTTTTCGATACCAACCTTCAGTACAATCAGGACATCGACCG
CATCATGCGCTCGACGATGGCGTTCAGCTGGAAGCCGGATGCCAACAAGGTGATCAACCTCGGCTACCGTTACTACCGCG
CCGATGCCAACACCGGGCAGCTGGCGCTGGAGCAGACCGACATCTCGGCGCAGTGGCCGCTGACGCGCCGCCTATATGGC
CTGGGGCGCATCGGCTACGACATGGATGCCAAGAAGCCGTCGGACATGCTGCTGGGCTTCGAATATGTCGCCGACTGCTG
GGTCGGGCGGCTGGCGGTGCAGCGCTACAGCAACGCGACCTCGGGCTATACGACGCACATCTTTGCCCAGATCGAGTTCA
AGGGGCTGTCGAAGGTGGGGAACAATCCGATCGACGTGATCCGACTCAACGTGCCCGGCTACCAGCCGGTCACCGCGCAG
CCGGTCACGCCGTCCGTGCTGGATCAATACGAATGA

Upstream 100 bases:

>100_bases
CGCCCGCCAGCCCTGTGCGGCCGGGCCACCGCGCGCCGAAGTACCGACCGATGACGTGCCGTGCGCGCCCGCTGCGCGCC
GCGCCCAGTTTCCGACTTGC

Downstream 100 bases:

>100_bases
CTATGGCTTGCAAATCGACTGCTGTCCGCTCTGCCACGCGCGTGGCGCCCACCCGCCGGCTGGGCATGGTGACCGGTGCG
CTGGTTGCGCTGATGGCTGG

Product: organic solvent tolerance transmembrane protein

Products: NA

Alternate protein names: Organic solvent tolerance protein

Number of amino acids: Translated: 811; Mature: 810

Protein sequence:

>811_residues
MTEPNRARKTRQRTAFAAPDQRTAPRRGALALRPLVFAVAGVWTAASAAQSQGATQQAASAQAPSSAASVTALAVSGPTT
PGGAPLVPKMAEPVKRPDNAVPSFAAADAMDGRTNEDIHLRGHGELRRNGTVVKGDTLDYNQDTDFATATGNVRLFRDGT
LVTGPDAALKVTANEGTMHTPSYEFHTVGGRGSAERIDFIDKDNSRITKGTYTTCSPDNVDWYFSASQIDIDSDRQVGSG
RAGVLHFLGMPVFASPVFDFPLNDERRSGFLAPVFGYSSRSGADVTLPYYFNIAPNRDLTLYPRLLSQRGLQLGAEYRYL
SQTYNGVLRGEFLPNDREADRNRWSIALVHNQRLATGLNAYVNYNKVSDSTYPDDLGRSIVTATQRQYTQEGGVTYSIGD
WVALARVQKFQTLSTATTALSPPYERVPQLNLSYNRYDVGGFDINFQTDYTKFSIPTENTVQGERLFMQPTISYPIIRPG
WFVTPKFILNTTSYRLDRPTGDTQASQINRTLPTVSLDSGLTFERDTPLVSKWFGRSYIQTLEPRLFYVYTPFRDQSQIP
LFDTAQSDYNLGQIFTENPYTGYDRIADNNKLTAGVTTRFIESETGIERLRATLAQRLDFEGQRVTLAGSAPTSVRRYSD
LLGATTIQMFRGIFFDTNLQYNQDIDRIMRSTMAFSWKPDANKVINLGYRYYRADANTGQLALEQTDISAQWPLTRRLYG
LGRIGYDMDAKKPSDMLLGFEYVADCWVGRLAVQRYSNATSGYTTHIFAQIEFKGLSKVGNNPIDVIRLNVPGYQPVTAQ
PVTPSVLDQYE

Sequences:

>Translated_811_residues
MTEPNRARKTRQRTAFAAPDQRTAPRRGALALRPLVFAVAGVWTAASAAQSQGATQQAASAQAPSSAASVTALAVSGPTT
PGGAPLVPKMAEPVKRPDNAVPSFAAADAMDGRTNEDIHLRGHGELRRNGTVVKGDTLDYNQDTDFATATGNVRLFRDGT
LVTGPDAALKVTANEGTMHTPSYEFHTVGGRGSAERIDFIDKDNSRITKGTYTTCSPDNVDWYFSASQIDIDSDRQVGSG
RAGVLHFLGMPVFASPVFDFPLNDERRSGFLAPVFGYSSRSGADVTLPYYFNIAPNRDLTLYPRLLSQRGLQLGAEYRYL
SQTYNGVLRGEFLPNDREADRNRWSIALVHNQRLATGLNAYVNYNKVSDSTYPDDLGRSIVTATQRQYTQEGGVTYSIGD
WVALARVQKFQTLSTATTALSPPYERVPQLNLSYNRYDVGGFDINFQTDYTKFSIPTENTVQGERLFMQPTISYPIIRPG
WFVTPKFILNTTSYRLDRPTGDTQASQINRTLPTVSLDSGLTFERDTPLVSKWFGRSYIQTLEPRLFYVYTPFRDQSQIP
LFDTAQSDYNLGQIFTENPYTGYDRIADNNKLTAGVTTRFIESETGIERLRATLAQRLDFEGQRVTLAGSAPTSVRRYSD
LLGATTIQMFRGIFFDTNLQYNQDIDRIMRSTMAFSWKPDANKVINLGYRYYRADANTGQLALEQTDISAQWPLTRRLYG
LGRIGYDMDAKKPSDMLLGFEYVADCWVGRLAVQRYSNATSGYTTHIFAQIEFKGLSKVGNNPIDVIRLNVPGYQPVTAQ
PVTPSVLDQYE
>Mature_810_residues
TEPNRARKTRQRTAFAAPDQRTAPRRGALALRPLVFAVAGVWTAASAAQSQGATQQAASAQAPSSAASVTALAVSGPTTP
GGAPLVPKMAEPVKRPDNAVPSFAAADAMDGRTNEDIHLRGHGELRRNGTVVKGDTLDYNQDTDFATATGNVRLFRDGTL
VTGPDAALKVTANEGTMHTPSYEFHTVGGRGSAERIDFIDKDNSRITKGTYTTCSPDNVDWYFSASQIDIDSDRQVGSGR
AGVLHFLGMPVFASPVFDFPLNDERRSGFLAPVFGYSSRSGADVTLPYYFNIAPNRDLTLYPRLLSQRGLQLGAEYRYLS
QTYNGVLRGEFLPNDREADRNRWSIALVHNQRLATGLNAYVNYNKVSDSTYPDDLGRSIVTATQRQYTQEGGVTYSIGDW
VALARVQKFQTLSTATTALSPPYERVPQLNLSYNRYDVGGFDINFQTDYTKFSIPTENTVQGERLFMQPTISYPIIRPGW
FVTPKFILNTTSYRLDRPTGDTQASQINRTLPTVSLDSGLTFERDTPLVSKWFGRSYIQTLEPRLFYVYTPFRDQSQIPL
FDTAQSDYNLGQIFTENPYTGYDRIADNNKLTAGVTTRFIESETGIERLRATLAQRLDFEGQRVTLAGSAPTSVRRYSDL
LGATTIQMFRGIFFDTNLQYNQDIDRIMRSTMAFSWKPDANKVINLGYRYYRADANTGQLALEQTDISAQWPLTRRLYGL
GRIGYDMDAKKPSDMLLGFEYVADCWVGRLAVQRYSNATSGYTTHIFAQIEFKGLSKVGNNPIDVIRLNVPGYQPVTAQP
VTPSVLDQYE

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family

Homologues:

Organism=Escherichia coli, GI1786239, Length=763, Percent_Identity=27.653997378768, Blast_Score=262, Evalue=6e-71,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): LPTD_RALSO (Q8Y221)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_518636.1
- GeneID:   1219319
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc0515
- NMPDR:   fig|267608.1.peg.515
- HOGENOM:   HBG701380
- OMA:   TPYYWNI
- ProtClustDB:   CLSK2302405
- BioCyc:   RSOL267608:RSC0515-MONOMER
- HAMAP:   MF_01411
- InterPro:   IPR020889
- InterPro:   IPR005653
- InterPro:   IPR007543

Pfam domain/function: PF03968 OstA; PF04453 OstA_C

EC number: NA

Molecular weight: Translated: 90163; Mature: 90031

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPNRARKTRQRTAFAAPDQRTAPRRGALALRPLVFAVAGVWTAASAAQSQGATQQAAS
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AQAPSSAASVTALAVSGPTTPGGAPLVPKMAEPVKRPDNAVPSFAAADAMDGRTNEDIHL
CCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHCCCCCCCCEEEE
RGHGELRRNGTVVKGDTLDYNQDTDFATATGNVRLFRDGTLVTGPDAALKVTANEGTMHT
ECCCCCCCCCEEEECCCCCCCCCCCCEEECCCEEEEECCEEEECCCCEEEEEECCCEEEC
PSYEFHTVGGRGSAERIDFIDKDNSRITKGTYTTCSPDNVDWYFSASQIDIDSDRQVGSG
CCEEEEECCCCCCCCCEEEEECCCCEEECCEEEECCCCCCEEEEECCEEECCCCCCCCCC
RAGVLHFLGMPVFASPVFDFPLNDERRSGFLAPVFGYSSRSGADVTLPYYFNIAPNRDLT
CCHHHHHHCCCHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEEEECCCCCCE
LYPRLLSQRGLQLGAEYRYLSQTYNGVLRGEFLPNDREADRNRWSIALVHNQRLATGLNA
EHHHHHHHCCHHCCCHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEEEECCHHHHCCCC
YVNYNKVSDSTYPDDLGRSIVTATQRQYTQEGGVTYSIGDWVALARVQKFQTLSTATTAL
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHC
SPPYERVPQLNLSYNRYDVGGFDINFQTDYTKFSIPTENTVQGERLFMQPTISYPIIRPG
CCCHHHCCCCCCCCCEEECCCEEEEEECCCEEEECCCCCCCCCCEEEECCCCCCCEECCC
WFVTPKFILNTTSYRLDRPTGDTQASQINRTLPTVSLDSGLTFERDTPLVSKWFGRSYIQ
CEECCCEEEECCCEEEECCCCCCHHHHHHHCCCEEECCCCCEECCCCCHHHHHHCHHHHH
TLEPRLFYVYTPFRDQSQIPLFDTAQSDYNLGQIFTENPYTGYDRIADNNKLTAGVTTRF
HCCCEEEEEECCCCCCCCCCEEECCCCCCCCCEEEECCCCCCHHHHCCCCEEEECCEEEE
IESETGIERLRATLAQRLDFEGQRVTLAGSAPTSVRRYSDLLGATTIQMFRGIFFDTNLQ
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCC
YNQDIDRIMRSTMAFSWKPDANKVINLGYRYYRADANTGQLALEQTDISAQWPLTRRLYG
CCHHHHHHHHHHHEEEECCCCCCEEECCEEEEECCCCCCEEEEEECCCCCCCCHHHHHHH
LGRIGYDMDAKKPSDMLLGFEYVADCWVGRLAVQRYSNATSGYTTHIFAQIEFKGLSKVG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEHHHCC
NNPIDVIRLNVPGYQPVTAQPVTPSVLDQYE
CCCEEEEEEECCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
TEPNRARKTRQRTAFAAPDQRTAPRRGALALRPLVFAVAGVWTAASAAQSQGATQQAAS
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AQAPSSAASVTALAVSGPTTPGGAPLVPKMAEPVKRPDNAVPSFAAADAMDGRTNEDIHL
CCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHCCCCCCCCEEEE
RGHGELRRNGTVVKGDTLDYNQDTDFATATGNVRLFRDGTLVTGPDAALKVTANEGTMHT
ECCCCCCCCCEEEECCCCCCCCCCCCEEECCCEEEEECCEEEECCCCEEEEEECCCEEEC
PSYEFHTVGGRGSAERIDFIDKDNSRITKGTYTTCSPDNVDWYFSASQIDIDSDRQVGSG
CCEEEEECCCCCCCCCEEEEECCCCEEECCEEEECCCCCCEEEEECCEEECCCCCCCCCC
RAGVLHFLGMPVFASPVFDFPLNDERRSGFLAPVFGYSSRSGADVTLPYYFNIAPNRDLT
CCHHHHHHCCCHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEEEECCCCCCE
LYPRLLSQRGLQLGAEYRYLSQTYNGVLRGEFLPNDREADRNRWSIALVHNQRLATGLNA
EHHHHHHHCCHHCCCHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEEEECCHHHHCCCC
YVNYNKVSDSTYPDDLGRSIVTATQRQYTQEGGVTYSIGDWVALARVQKFQTLSTATTAL
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHC
SPPYERVPQLNLSYNRYDVGGFDINFQTDYTKFSIPTENTVQGERLFMQPTISYPIIRPG
CCCHHHCCCCCCCCCEEECCCEEEEEECCCEEEECCCCCCCCCCEEEECCCCCCCEECCC
WFVTPKFILNTTSYRLDRPTGDTQASQINRTLPTVSLDSGLTFERDTPLVSKWFGRSYIQ
CEECCCEEEECCCEEEECCCCCCHHHHHHHCCCEEECCCCCEECCCCCHHHHHHCHHHHH
TLEPRLFYVYTPFRDQSQIPLFDTAQSDYNLGQIFTENPYTGYDRIADNNKLTAGVTTRF
HCCCEEEEEECCCCCCCCCCEEECCCCCCCCCEEEECCCCCCHHHHCCCCEEEECCEEEE
IESETGIERLRATLAQRLDFEGQRVTLAGSAPTSVRRYSDLLGATTIQMFRGIFFDTNLQ
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCC
YNQDIDRIMRSTMAFSWKPDANKVINLGYRYYRADANTGQLALEQTDISAQWPLTRRLYG
CCHHHHHHHHHHHEEEECCCCCCEEECCEEEEECCCCCCEEEEEECCCCCCCCHHHHHHH
LGRIGYDMDAKKPSDMLLGFEYVADCWVGRLAVQRYSNATSGYTTHIFAQIEFKGLSKVG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEHHHCC
NNPIDVIRLNVPGYQPVTAQPVTPSVLDQYE
CCCEEEEEEECCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852