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The map label for this gene is ruvC [H]

Identifier: 17545222

GI number: 17545222

Start: 537253

End: 537798

Strand: Reverse

Name: ruvC [H]

Synonym: RSc0503

Alternate gene names: 17545222

Gene position: 537798-537253 (Counterclockwise)

Preceding gene: 17545223

Following gene: 17545221

Centisome position: 14.47

GC content: 69.6

Gene sequence:

>546_bases
ATGCGCATCCTCGGCATCGACCCCGGCCTTCGCACCACCGGCTTCGGCGTGCTCGAGCGGCACGGCCACCAATTGGTCTA
CGTCGCCTCGGGCACGATCAAGAGCGACGGCAACGCCGACCTGCCCAGCCGCCTGAAGACGCTGTACGACGGCGTGTCGG
AGCTGGTGCGCACCTACCGGCCGGATTGCGCCTCCATCGAAAAGGTGTTCGTCAACGTCAACCCGCAGTCGACGCTGCTG
CTGGGCCAGGCGCGCGGTGCAGTGATCTGCGGGCTGATGAGCGGCAACCTGCCGGTGTTCGAATACACCGCGCTGCAACT
GAAGCAGGCCGTGGTCGGCTACGGCCGCGCCAACAAGGATCAGGTGCAGGACATGGTGGTGCGCCTGCTCAACCTGGAAG
GCCGGCCCGGCACCGATGCGGCCGACGCGCTGGGCGTGGCGATCTGCCATGCGCACGGCGGCGAAACCCTGGCCGCCATG
GCCGGACTGGCGCCGCAGCTGGCGCGCAAGGGCCTGCGCGTGCGGCGCGGCCGGCTGGTCGGCTAA

Upstream 100 bases:

>100_bases
TTCCGCCACTAAGCCACGAAGCATCACCCGCGGCTCCACCGCGCAACGGGGCAAGGCGTAGACTGTCGCCTGCCCCGTTT
TTCTTTTGCCTGTCCCCTTC

Downstream 100 bases:

>100_bases
GCCGCGCGCGAGCGCTCCCCAAACGCCGGCTGGCTGGCACCGGGCAGCACGGCCGTCTACCATGCGGGAGACCCCGTCTG
CAGGAGGCCCCCCGGATGCC

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MRILGIDPGLRTTGFGVLERHGHQLVYVASGTIKSDGNADLPSRLKTLYDGVSELVRTYRPDCASIEKVFVNVNPQSTLL
LGQARGAVICGLMSGNLPVFEYTALQLKQAVVGYGRANKDQVQDMVVRLLNLEGRPGTDAADALGVAICHAHGGETLAAM
AGLAPQLARKGLRVRRGRLVG

Sequences:

>Translated_181_residues
MRILGIDPGLRTTGFGVLERHGHQLVYVASGTIKSDGNADLPSRLKTLYDGVSELVRTYRPDCASIEKVFVNVNPQSTLL
LGQARGAVICGLMSGNLPVFEYTALQLKQAVVGYGRANKDQVQDMVVRLLNLEGRPGTDAADALGVAICHAHGGETLAAM
AGLAPQLARKGLRVRRGRLVG
>Mature_181_residues
MRILGIDPGLRTTGFGVLERHGHQLVYVASGTIKSDGNADLPSRLKTLYDGVSELVRTYRPDCASIEKVFVNVNPQSTLL
LGQARGAVICGLMSGNLPVFEYTALQLKQAVVGYGRANKDQVQDMVVRLLNLEGRPGTDAADALGVAICHAHGGETLAAM
AGLAPQLARKGLRVRRGRLVG

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=177, Percent_Identity=49.7175141242938, Blast_Score=143, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 19261; Mature: 19261

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILGIDPGLRTTGFGVLERHGHQLVYVASGTIKSDGNADLPSRLKTLYDGVSELVRTYR
CEEEECCCCCCCCCCHHHHHCCCEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHC
PDCASIEKVFVNVNPQSTLLLGQARGAVICGLMSGNLPVFEYTALQLKQAVVGYGRANKD
CCHHCEEEEEEECCCCCEEEEECCCCEEEEEEECCCCCEEHHHHHHHHHHHHHCCCCCHH
QVQDMVVRLLNLEGRPGTDAADALGVAICHAHGGETLAAMAGLAPQLARKGLRVRRGRLV
HHHHHHHHHHCCCCCCCCCHHHHHHHHEEECCCCCHHHHHHCCCHHHHHCCHHHHCCCCC
G
C
>Mature Secondary Structure
MRILGIDPGLRTTGFGVLERHGHQLVYVASGTIKSDGNADLPSRLKTLYDGVSELVRTYR
CEEEECCCCCCCCCCHHHHHCCCEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHC
PDCASIEKVFVNVNPQSTLLLGQARGAVICGLMSGNLPVFEYTALQLKQAVVGYGRANKD
CCHHCEEEEEEECCCCCEEEEECCCCEEEEEEECCCCCEEHHHHHHHHHHHHHCCCCCHH
QVQDMVVRLLNLEGRPGTDAADALGVAICHAHGGETLAAMAGLAPQLARKGLRVRRGRLV
HHHHHHHHHHCCCCCCCCCHHHHHHHHEEECCCCCHHHHHHCCCHHHHHCCHHHHCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA