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The map label for this gene is ruvA [H]

Identifier: 17545220

GI number: 17545220

Start: 535388

End: 535969

Strand: Reverse

Name: ruvA [H]

Synonym: RSc0501

Alternate gene names: 17545220

Gene position: 535969-535388 (Counterclockwise)

Preceding gene: 17545221

Following gene: 17545219

Centisome position: 14.42

GC content: 68.04

Gene sequence:

>582_bases
ATGATCGGACGCATCGCCGGGACGCTGATCGAAAAGAACCCGCCGCACCTGCTGGTCGACTGCCACGGCGTCGGCTATGA
AATCGACGTGCCGATGAGCACGTTCTACAACCTGCCCGCCACCGGCGAGAAGGTCGCGCTGCTCACCCAGCAGATCGTGC
GCGAGGATGCGCACCTGCTGTACGGCTTCGGCACCGCCGCCGAGCGCGAGACCTTCCGTCAGCTCATCAAGATCTCCGGC
ATCGGCGCGCGCATCGCGCTGGCGGTGCTGTCGGGCATGTCGGTGGCCGAACTGGCGCAGGCCGTGACGCTGCAGGAAGC
CGGACGGCTGACGCGCATTCCCGGCATCGGCAAAAAGACCGCCGAGCGCCTGCTGCTCGAACTCAAGGGCAAGCTCGGCG
CCGACCTGGGCACGGTGCCGGGCGGTCCGGCCGTGTCGGACGATGCGGTCGATGTGCTCAACGCCCTGCTGGCGCTGGGC
TACTCCGACAAGGAAGCCGCGCAGGCCATCAAGCAGGTGCCGGCCGGCACCGGCGTCTCCGAAGGCATCAAGCTGGCGCT
CAAGGCCCTCTCCAAGGGCTGA

Upstream 100 bases:

>100_bases
CGACGACCCGGCGGTCGGCCGGCAGGCCGTGGACACCCTCCAGCGCTAGCGCCGGCCCGGCATCGGCTACACTGCGTGCC
GTTTTGGGAGAACCTCATCC

Downstream 100 bases:

>100_bases
CGCCCCGGCGGCGCGAGACGGTAAAATGGCCCGTCCGCGGTCCCCCCGCGCCGTCTGCCCGCCATGATCGAAACCGACAA
GCTCGCCGCCAAGGCCGTCT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MIGRIAGTLIEKNPPHLLVDCHGVGYEIDVPMSTFYNLPATGEKVALLTQQIVREDAHLLYGFGTAAERETFRQLIKISG
IGARIALAVLSGMSVAELAQAVTLQEAGRLTRIPGIGKKTAERLLLELKGKLGADLGTVPGGPAVSDDAVDVLNALLALG
YSDKEAAQAIKQVPAGTGVSEGIKLALKALSKG

Sequences:

>Translated_193_residues
MIGRIAGTLIEKNPPHLLVDCHGVGYEIDVPMSTFYNLPATGEKVALLTQQIVREDAHLLYGFGTAAERETFRQLIKISG
IGARIALAVLSGMSVAELAQAVTLQEAGRLTRIPGIGKKTAERLLLELKGKLGADLGTVPGGPAVSDDAVDVLNALLALG
YSDKEAAQAIKQVPAGTGVSEGIKLALKALSKG
>Mature_193_residues
MIGRIAGTLIEKNPPHLLVDCHGVGYEIDVPMSTFYNLPATGEKVALLTQQIVREDAHLLYGFGTAAERETFRQLIKISG
IGARIALAVLSGMSVAELAQAVTLQEAGRLTRIPGIGKKTAERLLLELKGKLGADLGTVPGGPAVSDDAVDVLNALLALG
YSDKEAAQAIKQVPAGTGVSEGIKLALKALSKG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=44.7761194029851, Blast_Score=173, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 20107; Mature: 20107

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRIAGTLIEKNPPHLLVDCHGVGYEIDVPMSTFYNLPATGEKVALLTQQIVREDAHLL
CCCCHHHHHHCCCCCEEEEEECCCCEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHEE
YGFGTAAERETFRQLIKISGIGARIALAVLSGMSVAELAQAVTLQEAGRLTRIPGIGKKT
EECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHH
AERLLLELKGKLGADLGTVPGGPAVSDDAVDVLNALLALGYSDKEAAQAIKQVPAGTGVS
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHH
EGIKLALKALSKG
HHHHHHHHHHHCC
>Mature Secondary Structure
MIGRIAGTLIEKNPPHLLVDCHGVGYEIDVPMSTFYNLPATGEKVALLTQQIVREDAHLL
CCCCHHHHHHCCCCCEEEEEECCCCEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHEE
YGFGTAAERETFRQLIKISGIGARIALAVLSGMSVAELAQAVTLQEAGRLTRIPGIGKKT
EECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHH
AERLLLELKGKLGADLGTVPGGPAVSDDAVDVLNALLALGYSDKEAAQAIKQVPAGTGVS
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHH
EGIKLALKALSKG
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA