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The map label for this gene is ruvB [H]

Identifier: 17545219

GI number: 17545219

Start: 534251

End: 535324

Strand: Reverse

Name: ruvB [H]

Synonym: RSc0500

Alternate gene names: 17545219

Gene position: 535324-534251 (Counterclockwise)

Preceding gene: 17545220

Following gene: 17545214

Centisome position: 14.4

GC content: 69.37

Gene sequence:

>1074_bases
ATGATCGAAACCGACAAGCTCGCCGCCAAGGCCGTCTCCGCTGAACGCCTGATCTCGGCCTCGCCCGCCTCCCCCAACGA
GGAGGCATTCGAGCGCGCGCTGCGCCCCAAGCTGCTCGACGAATACGTCGGCCAGGAAAAGGTGCGCGGCCAGCTCGATA
TCTTCATGACGGCGGCCAAGAAGCGCCGCGAGGCGCTCGACCACGTGCTGCTGTTCGGCCCGCCGGGCCTGGGCAAGACG
ACGCTGGCGCACATCATCGCCCGCGAGATGGGCGTCAACCTGCGCCAGACCTCGGGCCCCGTGCTGGAGCGCCCGGGCGA
CCTGGCCGCGCTGCTGACCAACCTCGAAGCCAACGACGTCCTCTTCATCGACGAGATCCATCGACTCTCGCCGGTGGTGG
AGGAAATCCTGTATCCGGCGCTCGAGGACTACCAGATCGACATCATGATCGGCGAAGGCCCGGCAGCCCGCTCGGTCAAG
CTCGATCTGCAGCCGTTCACGCTGGTGGGCGCCACCACGCGCGCCGGCATGCTGACCAACCCGCTGCGCGACCGCTTCGG
CATCGTCGCCCGGCTCGAGTTCTATACGCCGACGGAGCTCGCGCGCATCGTCACGCGCTCGGCCGGCCTGCTCGACGCGC
GCATCGCCGAAGACGGCGCGCTGGAGATCGCCAAGCGCTCGCGCGGCACGCCCCGCATCGCCAACCGCCTGCTGCGCCGC
GTGCGCGACTACGCTGAAGTGAAAGCCGACGGCGTCATCACCCGCGCGGTGGCCGACGCGGCGCTGGCGATGCTCGACGT
GGATGCGGTCGGCTTCGACCTGATGGACCGCAAGCTGCTGGAAGCCATCCTGCACAAGTTCAACGGCGGCCCGGTCGGCA
TCGACAACCTGGCCGCCGCCATCGGCGAGGAGCGCGACACCATCGAAGACGTGCTCGAGCCCTACCTGATCCAGCAGGGC
TACCTGCAGCGCACGCCGCGCGGGCGCGTCGCCACGGCATCGGCCTACCAGCACTTCGGGCTGGGCGCGCCGAAGACCGG
TCCGGCGCGCGACCTGTGGGACAACAACGCCTAG

Upstream 100 bases:

>100_bases
CATCAAGCTGGCGCTCAAGGCCCTCTCCAAGGGCTGACGCCCCGGCGGCGCGAGACGGTAAAATGGCCCGTCCGCGGTCC
CCCCGCGCCGTCTGCCCGCC

Downstream 100 bases:

>100_bases
CCGATCAGCCGCAGCATCGGCGCATCGGCTGCATGCCGCCCCGGCCGCGGGTCTGAGGCCACCCTACGGTACGCGCCGAT
CCACTTCGTCGAGCACCAGC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MIETDKLAAKAVSAERLISASPASPNEEAFERALRPKLLDEYVGQEKVRGQLDIFMTAAKKRREALDHVLLFGPPGLGKT
TLAHIIAREMGVNLRQTSGPVLERPGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVK
LDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTPTELARIVTRSAGLLDARIAEDGALEIAKRSRGTPRIANRLLRR
VRDYAEVKADGVITRAVADAALAMLDVDAVGFDLMDRKLLEAILHKFNGGPVGIDNLAAAIGEERDTIEDVLEPYLIQQG
YLQRTPRGRVATASAYQHFGLGAPKTGPARDLWDNNA

Sequences:

>Translated_357_residues
MIETDKLAAKAVSAERLISASPASPNEEAFERALRPKLLDEYVGQEKVRGQLDIFMTAAKKRREALDHVLLFGPPGLGKT
TLAHIIAREMGVNLRQTSGPVLERPGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVK
LDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTPTELARIVTRSAGLLDARIAEDGALEIAKRSRGTPRIANRLLRR
VRDYAEVKADGVITRAVADAALAMLDVDAVGFDLMDRKLLEAILHKFNGGPVGIDNLAAAIGEERDTIEDVLEPYLIQQG
YLQRTPRGRVATASAYQHFGLGAPKTGPARDLWDNNA
>Mature_357_residues
MIETDKLAAKAVSAERLISASPASPNEEAFERALRPKLLDEYVGQEKVRGQLDIFMTAAKKRREALDHVLLFGPPGLGKT
TLAHIIAREMGVNLRQTSGPVLERPGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVK
LDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTPTELARIVTRSAGLLDARIAEDGALEIAKRSRGTPRIANRLLRR
VRDYAEVKADGVITRAVADAALAMLDVDAVGFDLMDRKLLEAILHKFNGGPVGIDNLAAAIGEERDTIEDVLEPYLIQQG
YLQRTPRGRVATASAYQHFGLGAPKTGPARDLWDNNA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=334, Percent_Identity=71.8562874251497, Blast_Score=486, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 39059; Mature: 39059

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETDKLAAKAVSAERLISASPASPNEEAFERALRPKLLDEYVGQEKVRGQLDIFMTAAK
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHH
KRREALDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERPGDLAALLTNLEANDV
HHHHHHHHEEEECCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHCCCCCCE
LFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQPFTLVGATTRAGMLTN
EEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCEEEEECCHHCCHHHH
PLRDRFGIVARLEFYTPTELARIVTRSAGLLDARIAEDGALEIAKRSRGTPRIANRLLRR
HHHHHHCEEEEEEECCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHCCCCHHHHHHHHHH
VRDYAEVKADGVITRAVADAALAMLDVDAVGFDLMDRKLLEAILHKFNGGPVGIDNLAAA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
IGEERDTIEDVLEPYLIQQGYLQRTPRGRVATASAYQHFGLGAPKTGPARDLWDNNA
HCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIETDKLAAKAVSAERLISASPASPNEEAFERALRPKLLDEYVGQEKVRGQLDIFMTAAK
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHH
KRREALDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERPGDLAALLTNLEANDV
HHHHHHHHEEEECCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHCCCCCCE
LFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQPFTLVGATTRAGMLTN
EEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCEEEEECCHHCCHHHH
PLRDRFGIVARLEFYTPTELARIVTRSAGLLDARIAEDGALEIAKRSRGTPRIANRLLRR
HHHHHHCEEEEEEECCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHCCCCHHHHHHHHHH
VRDYAEVKADGVITRAVADAALAMLDVDAVGFDLMDRKLLEAILHKFNGGPVGIDNLAAA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
IGEERDTIEDVLEPYLIQQGYLQRTPRGRVATASAYQHFGLGAPKTGPARDLWDNNA
HCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA