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The map label for this gene is yhcS [C]

Identifier: 17544962

GI number: 17544962

Start: 267441

End: 268373

Strand: Reverse

Name: yhcS [C]

Synonym: RSc0243

Alternate gene names: 17544962

Gene position: 268373-267441 (Counterclockwise)

Preceding gene: 17544964

Following gene: 17544961

Centisome position: 7.22

GC content: 69.24

Gene sequence:

>933_bases
ATGGACCGCTTTCTCAGTATCGAAGCCTTCGTGCGCGTGGCCGAGACACGCAGCTTTGCCGAAGCGGCGCGCCAGCTGGG
TGTCACGAACTCCGTGGTGACGCATCGCGTGCAGCAGCTGGAGCGCTTCATCGAGGCGCCGCTGTTCCATCGCAGCACGC
GGCACGTGCGGCTGTCCGAGGTCGGCGAGACCTACTACAAGCAGTGCGCCCACGCCGTCGGCATGCTGTCGGACCTGACC
GACCAGATGCGCGGCCTGCGCGCCACCCCGGCGGGCAAGCTGCGCATCCGCATGCTGCCGGGCTATGCGCTGCACCACTT
CGCCCAGCCGCTGGCGCGGTTCGGCGCGCAGTACCCCGACCTCCAGCTCGACGTGGTGGTGGACGACGGCGTGGTCGACC
CGATCGCGGAAGGGTTCGACGTGGTGTTCCAGATCTTTCCGCCGATCAACGATTCGCTGATCGAGAAGCGCCTGTTCATC
CTGCGCCGCCTGTTCTGCGCCACGCCGGACTACGTGGAGGAGTACGGCATGCCGCAACAGCCGGCCGACCTGCAGCGGCA
CGCGCTGGCCCTGTATTCCGGCTACCCGACGCGCAAGCACTGGGTGTTCTCGCGCAGCGGCGAGGTGGCCGCCGAACTCG
ACCTGCCCGAGCAGGTCCGCTCGAATTCGGTCCACCTGCTGCGCGACTATGCGCTGACCGGCGCCGGCATCGCATGCCTG
CCGACGCTCGTCGCCAGCGACGACCTGCTCGCCGGCCGGCTGGTGCCGGTGCTGCCCGACTACGACCTGGCGCCGTTCCA
CTTCTCGGCGGTGTATCCCGCCACGCAGCGGCAGGCGGTCAAGGTGTGCGCGCTGATCGATTGCCTGGCCAGCCACCACG
CCGGCGAACCGGCATGGGACACCCCGCTGCTGGCGCGCGGCTGGATCCGCTGA

Upstream 100 bases:

>100_bases
CCGCGCCGGCCCGGCGGACCGCTCTATGATGGCGGGATCGCGCGGCCCGCATCCGCCGGGCCGGACATGCCTTCCACCCC
GATCAGGCCCGGAGCCTCGA

Downstream 100 bases:

>100_bases
CGCGGCGCCGGACGGACGGGCGGCACGCCGGATATTTCGCGGCGGCGCGCGCATTGTTCGCAAAGCGCAAAAACTGCGCT
CGGCGATCCGGCCGTTGTGG

Product: transcriptional regulator transcription regulator protein

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MDRFLSIEAFVRVAETRSFAEAARQLGVTNSVVTHRVQQLERFIEAPLFHRSTRHVRLSEVGETYYKQCAHAVGMLSDLT
DQMRGLRATPAGKLRIRMLPGYALHHFAQPLARFGAQYPDLQLDVVVDDGVVDPIAEGFDVVFQIFPPINDSLIEKRLFI
LRRLFCATPDYVEEYGMPQQPADLQRHALALYSGYPTRKHWVFSRSGEVAAELDLPEQVRSNSVHLLRDYALTGAGIACL
PTLVASDDLLAGRLVPVLPDYDLAPFHFSAVYPATQRQAVKVCALIDCLASHHAGEPAWDTPLLARGWIR

Sequences:

>Translated_310_residues
MDRFLSIEAFVRVAETRSFAEAARQLGVTNSVVTHRVQQLERFIEAPLFHRSTRHVRLSEVGETYYKQCAHAVGMLSDLT
DQMRGLRATPAGKLRIRMLPGYALHHFAQPLARFGAQYPDLQLDVVVDDGVVDPIAEGFDVVFQIFPPINDSLIEKRLFI
LRRLFCATPDYVEEYGMPQQPADLQRHALALYSGYPTRKHWVFSRSGEVAAELDLPEQVRSNSVHLLRDYALTGAGIACL
PTLVASDDLLAGRLVPVLPDYDLAPFHFSAVYPATQRQAVKVCALIDCLASHHAGEPAWDTPLLARGWIR
>Mature_310_residues
MDRFLSIEAFVRVAETRSFAEAARQLGVTNSVVTHRVQQLERFIEAPLFHRSTRHVRLSEVGETYYKQCAHAVGMLSDLT
DQMRGLRATPAGKLRIRMLPGYALHHFAQPLARFGAQYPDLQLDVVVDDGVVDPIAEGFDVVFQIFPPINDSLIEKRLFI
LRRLFCATPDYVEEYGMPQQPADLQRHALALYSGYPTRKHWVFSRSGEVAAELDLPEQVRSNSVHLLRDYALTGAGIACL
PTLVASDDLLAGRLVPVLPDYDLAPFHFSAVYPATQRQAVKVCALIDCLASHHAGEPAWDTPLLARGWIR

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=292, Percent_Identity=30.4794520547945, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=31.6151202749141, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=30.6397306397306, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787128, Length=282, Percent_Identity=29.7872340425532, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI87081978, Length=290, Percent_Identity=28.9655172413793, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1789440, Length=280, Percent_Identity=28.9285714285714, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789173, Length=293, Percent_Identity=26.6211604095563, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1787589, Length=288, Percent_Identity=26.0416666666667, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI145693105, Length=121, Percent_Identity=24.7933884297521, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790783, Length=270, Percent_Identity=24.4444444444444, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI157672245, Length=151, Percent_Identity=29.1390728476821, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34730; Mature: 34730

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRFLSIEAFVRVAETRSFAEAARQLGVTNSVVTHRVQQLERFIEAPLFHRSTRHVRLSE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHH
VGETYYKQCAHAVGMLSDLTDQMRGLRATPAGKLRIRMLPGYALHHFAQPLARFGAQYPD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCC
LQLDVVVDDGVVDPIAEGFDVVFQIFPPINDSLIEKRLFILRRLFCATPDYVEEYGMPQQ
CEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
PADLQRHALALYSGYPTRKHWVFSRSGEVAAELDLPEQVRSNSVHLLRDYALTGAGIACL
CHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCHHHHHCCCHHHHHHHHHCCCCHHHH
PTLVASDDLLAGRLVPVLPDYDLAPFHFSAVYPATQRQAVKVCALIDCLASHHAGEPAWD
HHHHHCCCHHHCCCCCCCCCCCCCCCEEHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCC
TPLLARGWIR
CCHHHCCCCC
>Mature Secondary Structure
MDRFLSIEAFVRVAETRSFAEAARQLGVTNSVVTHRVQQLERFIEAPLFHRSTRHVRLSE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHH
VGETYYKQCAHAVGMLSDLTDQMRGLRATPAGKLRIRMLPGYALHHFAQPLARFGAQYPD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCC
LQLDVVVDDGVVDPIAEGFDVVFQIFPPINDSLIEKRLFILRRLFCATPDYVEEYGMPQQ
CEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
PADLQRHALALYSGYPTRKHWVFSRSGEVAAELDLPEQVRSNSVHLLRDYALTGAGIACL
CHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCHHHHHCCCHHHHHHHHHCCCCHHHH
PTLVASDDLLAGRLVPVLPDYDLAPFHFSAVYPATQRQAVKVCALIDCLASHHAGEPAWD
HHHHHCCCHHHCCCCCCCCCCCCCCCEEHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCC
TPLLARGWIR
CCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]