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The map label for this gene is rtcB [H]

Identifier: 17544943

GI number: 17544943

Start: 246150

End: 247370

Strand: Direct

Name: rtcB [H]

Synonym: RSc0224

Alternate gene names: 17544943

Gene position: 246150-247370 (Clockwise)

Preceding gene: 17544942

Following gene: 17544944

Centisome position: 6.62

GC content: 66.26

Gene sequence:

>1221_bases
ATGAGCAATACCAGTTACGACACCCTCCACGTCGACAACGGCGCCGACATCAAGCTGTGGACCCACGGCGTGCCGGTGGA
AGACGACGCCCGCAAGCAACTGATGAACACGGCGAAGATGCCCTTCATCTTCAAGCACCTGGCGGTGATGCCGGACGTGC
ACCTGGGCAAGGGGTCGACCATCGGCAGCGTGATCCCGACGCGGGGCGCGATCATCCCGGCGGCCGTCGGCGTGGATATC
GGCTGCGGCATGATGGCCGCGCGCACCACGCTCACCGCGACCGACCTGCCGGACAACCTGCACGGCCTGCGCAGCGCCAT
CGAGGCGGCGGTACCGCACGGCCGTACGCCTGGCGCGCGCGACAAGGGGGCCTGGAGCACGCCGCCGGCCACGGTCGATG
CGATGTGGGCGGAACTGGCCGAGGGCTTCCAGCGGATCACCGACAAGTATCCGCGGCTCAGGAAGACGAACAACCACAAG
CACCTCGGAACGCTCGGTACCGGCAACCACTTCATCGAGGTCTGCCTGGATGAAGAGAACCGCGTCTGGTTCATGCTGCA
CTCCGGTTCGCGCGGCGTGGGCAATGCGATCGGCAACCTGTTCATTGAACTGGCGCAGGCCGATATGCGGCAGCATATCG
CCAACCTGCCGGACCGCGACCTGGCGTATTTCGAGGAAGGCAGCGAGCACTTTGACGACTACGTGGAGGCGGTGGGCTGG
GCGCAGGACTACGCGCGCCGCAACCGCGCCACGATGATGCAGAACGTGATCGCGGCCGCGCGCAAGGTGATCGCCAAGCC
GTTCGCGGCGGACGTCGAGGCGGTGAACTGCCACCACAATTACGTGCAGCGCGAGACCCACTTCGGCCACGAGGTGCTGG
TGACGCGCAAGGGCGCGGTGTCGGCACAGAAGGGGCAGCTCGGCATCATTCCGGGTTCGATGGGCGCCAAGAGCTTCATC
GTGCGCGGGCTGGGCAACGAAGAAGCGTTCTGCTCGTGCAGCCACGGCGCGGGCCGCACCATGAGCCGCACGCAGGCCAA
GAAGCGCTACACGGTGGATGACCAGGTCCGTGCCACCGCGCACGTGGAGTGCCGCAAGGATGCCGACGTCATCGACGAAA
TCCCGATGGCGTACAAGGACATCGACGCCGTGATGGCCGCGCAGGCGGACCTGGTGGAGATCGTCCATACGCTGCGGCAG
GTGGTGTGCGTGAAGGGGTAG

Upstream 100 bases:

>100_bases
AGGGCTATGTCGATTCCACCGCGGTGCGCTGCCTGGCTTGCCGCCGACAGCGCCGCGGCGCACGCATGAACAACAACAAA
GACAACTCGATCAAAGCATC

Downstream 100 bases:

>100_bases
CCTGCCGGGGGTAGGCCACCGTCGAAGCGAAGGCGCCGCGCGCTGTCCGGCGTGCCCGGGACCCGCCATCCGGCCGGGCT
CGGGCACAATGCCGCACGCC

Product: RTCB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSNTSYDTLHVDNGADIKLWTHGVPVEDDARKQLMNTAKMPFIFKHLAVMPDVHLGKGSTIGSVIPTRGAIIPAAVGVDI
GCGMMAARTTLTATDLPDNLHGLRSAIEAAVPHGRTPGARDKGAWSTPPATVDAMWAELAEGFQRITDKYPRLRKTNNHK
HLGTLGTGNHFIEVCLDEENRVWFMLHSGSRGVGNAIGNLFIELAQADMRQHIANLPDRDLAYFEEGSEHFDDYVEAVGW
AQDYARRNRATMMQNVIAAARKVIAKPFAADVEAVNCHHNYVQRETHFGHEVLVTRKGAVSAQKGQLGIIPGSMGAKSFI
VRGLGNEEAFCSCSHGAGRTMSRTQAKKRYTVDDQVRATAHVECRKDADVIDEIPMAYKDIDAVMAAQADLVEIVHTLRQ
VVCVKG

Sequences:

>Translated_406_residues
MSNTSYDTLHVDNGADIKLWTHGVPVEDDARKQLMNTAKMPFIFKHLAVMPDVHLGKGSTIGSVIPTRGAIIPAAVGVDI
GCGMMAARTTLTATDLPDNLHGLRSAIEAAVPHGRTPGARDKGAWSTPPATVDAMWAELAEGFQRITDKYPRLRKTNNHK
HLGTLGTGNHFIEVCLDEENRVWFMLHSGSRGVGNAIGNLFIELAQADMRQHIANLPDRDLAYFEEGSEHFDDYVEAVGW
AQDYARRNRATMMQNVIAAARKVIAKPFAADVEAVNCHHNYVQRETHFGHEVLVTRKGAVSAQKGQLGIIPGSMGAKSFI
VRGLGNEEAFCSCSHGAGRTMSRTQAKKRYTVDDQVRATAHVECRKDADVIDEIPMAYKDIDAVMAAQADLVEIVHTLRQ
VVCVKG
>Mature_405_residues
SNTSYDTLHVDNGADIKLWTHGVPVEDDARKQLMNTAKMPFIFKHLAVMPDVHLGKGSTIGSVIPTRGAIIPAAVGVDIG
CGMMAARTTLTATDLPDNLHGLRSAIEAAVPHGRTPGARDKGAWSTPPATVDAMWAELAEGFQRITDKYPRLRKTNNHKH
LGTLGTGNHFIEVCLDEENRVWFMLHSGSRGVGNAIGNLFIELAQADMRQHIANLPDRDLAYFEEGSEHFDDYVEAVGWA
QDYARRNRATMMQNVIAAARKVIAKPFAADVEAVNCHHNYVQRETHFGHEVLVTRKGAVSAQKGQLGIIPGSMGAKSFIV
RGLGNEEAFCSCSHGAGRTMSRTQAKKRYTVDDQVRATAHVECRKDADVIDEIPMAYKDIDAVMAAQADLVEIVHTLRQV
VCVKG

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=445, Percent_Identity=27.4157303370787, Blast_Score=123, Evalue=4e-28,
Organism=Escherichia coli, GI2367224, Length=408, Percent_Identity=71.8137254901961, Blast_Score=627, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17506665, Length=446, Percent_Identity=27.1300448430493, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24585217, Length=448, Percent_Identity=29.0178571428571, Blast_Score=112, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 44398; Mature: 44267

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS01288 UPF0027

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTSYDTLHVDNGADIKLWTHGVPVEDDARKQLMNTAKMPFIFKHLAVMPDVHLGKGST
CCCCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
IGSVIPTRGAIIPAAVGVDIGCGMMAARTTLTATDLPDNLHGLRSAIEAAVPHGRTPGAR
CCCCCCCCCCEEHHHHCCCCCCCHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCCCCC
DKGAWSTPPATVDAMWAELAEGFQRITDKYPRLRKTNNHKHLGTLGTGNHFIEVCLDEEN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCCEEEEEEECCCC
RVWFMLHSGSRGVGNAIGNLFIELAQADMRQHIANLPDRDLAYFEEGSEHFDDYVEAVGW
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHH
AQDYARRNRATMMQNVIAAARKVIAKPFAADVEAVNCHHNYVQRETHFGHEVLVTRKGAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCC
SAQKGQLGIIPGSMGAKSFIVRGLGNEEAFCSCSHGAGRTMSRTQAKKRYTVDDQVRATA
CCCCCCEEECCCCCCHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCHHHHHEE
HVECRKDADVIDEIPMAYKDIDAVMAAQADLVEIVHTLRQVVCVKG
EEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNTSYDTLHVDNGADIKLWTHGVPVEDDARKQLMNTAKMPFIFKHLAVMPDVHLGKGST
CCCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
IGSVIPTRGAIIPAAVGVDIGCGMMAARTTLTATDLPDNLHGLRSAIEAAVPHGRTPGAR
CCCCCCCCCCEEHHHHCCCCCCCHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCCCCC
DKGAWSTPPATVDAMWAELAEGFQRITDKYPRLRKTNNHKHLGTLGTGNHFIEVCLDEEN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCCEEEEEEECCCC
RVWFMLHSGSRGVGNAIGNLFIELAQADMRQHIANLPDRDLAYFEEGSEHFDDYVEAVGW
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHH
AQDYARRNRATMMQNVIAAARKVIAKPFAADVEAVNCHHNYVQRETHFGHEVLVTRKGAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCC
SAQKGQLGIIPGSMGAKSFIVRGLGNEEAFCSCSHGAGRTMSRTQAKKRYTVDDQVRATA
CCCCCCEEECCCCCCHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCHHHHHEE
HVECRKDADVIDEIPMAYKDIDAVMAAQADLVEIVHTLRQVVCVKG
EEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 9738023 [H]