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The map label for this gene is yfdH [C]

Identifier: 17232610

GI number: 17232610

Start: 6114366

End: 6115355

Strand: Reverse

Name: yfdH [C]

Synonym: all5118

Alternate gene names: 17232610

Gene position: 6115355-6114366 (Counterclockwise)

Preceding gene: 17232611

Following gene: 17232608

Centisome position: 95.35

GC content: 40.1

Gene sequence:

>990_bases
ATGCCACCTAAATATTCTTTTATCGTCCCAATTTACAACGAAGAAGAAACCATCACAGAAATGTATCGCCGCATTTCCCA
GGTAATGGATCAGATGGATGGTTCAGTCGAGTTGTGTTTAGTCAACGATGGTAGCCGCGATCGCTCTCTAAAAATGATGC
GAGAATTACATCAAAAAGATCCGCGTGTTGTCTACTTAAGTCTTGCCAGAAATTTTGGTCACCAAATCGCCGTCACCGCA
GGTTTGAATTTTGCCCGTGGACAAATAGTTGTGATTCTCGATGCTGATTTACAAGATCCACCAGAATTGATCGCGGAAAT
GGTGGAACTATGGCGGCAAGGATATCATATAATTTATGCCCAAAGAATCAAACGCCGTCAAGAAGGCTGGTTTAAACGCT
TTACCGCCTACGCTTTTTATCGGATTCTCAAACAGCTAGCAGATGTTGATATTCCTACAGATACGGGAGACTTTTGTTTA
TTAGATAGACAAGTTGTCGATGTACTCAATGCCATGCCAGAGCGAAATCGTTACATTCGCGGCTTGCGTTCTTGGGTAGG
TTTTAACCAAACAGCCGTTAAATTTGAACGAGATCCGCGTTTTGCTGGCGATGTCAAATATACTTTTCGTAAATCTTTCG
CATTGGCAATTAATGGCATAGTTTCCTTTTCTAAAGTGCCATTAAGGCTTTCAACTTATTTAGGACTATTTGCCGCAATA
GCCTCATTATTAATGTGTCTATTAGTTTTATATTGGCGGATTTTTACACCCCATTCTCCCCTAACTGGAATCGCCATTAT
TCTCATAGCTATCTTCTTTTTGGGAGCAGTACAACTTGTCAGTATTGGTATTTTAGGTGAGTATATCGGGCGAATTTATG
AAGAGGTTAAACAAAGACCACTTTATACATTGTCAGAAGTTAGCGGCTTTGAGCAGCAATATCCTGATGTTCAACAATCA
TTAGATACTTCCTCATCTTCATCAAATTAA

Upstream 100 bases:

>100_bases
TGGTGCTTTGGCATTGATTGGAATGCTAGTTGGTGGTTCCACTTGGTATCGTCGTCGTCGCTCTTTTCCCACTCGTAAAA
AACCCTAACAAATTTCAACT

Downstream 100 bases:

>100_bases
GAACCAATTATTACAGTTAAGTAAATCATTAGAACTGAGTTCGTAGCTGTATTTTCTAACTACAAACCATTGCTACCTTA
ATTACTTTCCGCGCTTTCAT

Product: hypothetical protein

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MPPKYSFIVPIYNEEETITEMYRRISQVMDQMDGSVELCLVNDGSRDRSLKMMRELHQKDPRVVYLSLARNFGHQIAVTA
GLNFARGQIVVILDADLQDPPELIAEMVELWRQGYHIIYAQRIKRRQEGWFKRFTAYAFYRILKQLADVDIPTDTGDFCL
LDRQVVDVLNAMPERNRYIRGLRSWVGFNQTAVKFERDPRFAGDVKYTFRKSFALAINGIVSFSKVPLRLSTYLGLFAAI
ASLLMCLLVLYWRIFTPHSPLTGIAIILIAIFFLGAVQLVSIGILGEYIGRIYEEVKQRPLYTLSEVSGFEQQYPDVQQS
LDTSSSSSN

Sequences:

>Translated_329_residues
MPPKYSFIVPIYNEEETITEMYRRISQVMDQMDGSVELCLVNDGSRDRSLKMMRELHQKDPRVVYLSLARNFGHQIAVTA
GLNFARGQIVVILDADLQDPPELIAEMVELWRQGYHIIYAQRIKRRQEGWFKRFTAYAFYRILKQLADVDIPTDTGDFCL
LDRQVVDVLNAMPERNRYIRGLRSWVGFNQTAVKFERDPRFAGDVKYTFRKSFALAINGIVSFSKVPLRLSTYLGLFAAI
ASLLMCLLVLYWRIFTPHSPLTGIAIILIAIFFLGAVQLVSIGILGEYIGRIYEEVKQRPLYTLSEVSGFEQQYPDVQQS
LDTSSSSSN
>Mature_328_residues
PPKYSFIVPIYNEEETITEMYRRISQVMDQMDGSVELCLVNDGSRDRSLKMMRELHQKDPRVVYLSLARNFGHQIAVTAG
LNFARGQIVVILDADLQDPPELIAEMVELWRQGYHIIYAQRIKRRQEGWFKRFTAYAFYRILKQLADVDIPTDTGDFCLL
DRQVVDVLNAMPERNRYIRGLRSWVGFNQTAVKFERDPRFAGDVKYTFRKSFALAINGIVSFSKVPLRLSTYLGLFAAIA
SLLMCLLVLYWRIFTPHSPLTGIAIILIAIFFLGAVQLVSIGILGEYIGRIYEEVKQRPLYTLSEVSGFEQQYPDVQQSL
DTSSSSSN

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788692, Length=306, Percent_Identity=40.1960784313725, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1788588, Length=311, Percent_Identity=31.1897106109325, Blast_Score=167, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71999402, Length=190, Percent_Identity=30.5263157894737, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 37793; Mature: 37662

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPKYSFIVPIYNEEETITEMYRRISQVMDQMDGSVELCLVNDGSRDRSLKMMRELHQKD
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCC
PRVVYLSLARNFGHQIAVTAGLNFARGQIVVILDADLQDPPELIAEMVELWRQGYHIIYA
CCEEEEEHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHH
QRIKRRQEGWFKRFTAYAFYRILKQLADVDIPTDTGDFCLLDRQVVDVLNAMPERNRYIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCHHHHHHH
GLRSWVGFNQTAVKFERDPRFAGDVKYTFRKSFALAINGIVSFSKVPLRLSTYLGLFAAI
HHHHHHCCCCHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ASLLMCLLVLYWRIFTPHSPLTGIAIILIAIFFLGAVQLVSIGILGEYIGRIYEEVKQRP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LYTLSEVSGFEQQYPDVQQSLDTSSSSSN
CHHHHHHCCHHHHCCHHHHHCCCCCCCCC
>Mature Secondary Structure 
PPKYSFIVPIYNEEETITEMYRRISQVMDQMDGSVELCLVNDGSRDRSLKMMRELHQKD
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCC
PRVVYLSLARNFGHQIAVTAGLNFARGQIVVILDADLQDPPELIAEMVELWRQGYHIIYA
CCEEEEEHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHH
QRIKRRQEGWFKRFTAYAFYRILKQLADVDIPTDTGDFCLLDRQVVDVLNAMPERNRYIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCHHHHHHH
GLRSWVGFNQTAVKFERDPRFAGDVKYTFRKSFALAINGIVSFSKVPLRLSTYLGLFAAI
HHHHHHCCCCHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ASLLMCLLVLYWRIFTPHSPLTGIAIILIAIFFLGAVQLVSIGILGEYIGRIYEEVKQRP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LYTLSEVSGFEQQYPDVQQSLDTSSSSSN
CHHHHHHCCHHHHCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]