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The map label for this gene is ndh [H]

Identifier: 17231586

GI number: 17231586

Start: 4932447

End: 4933676

Strand: Direct

Name: ndh [H]

Synonym: alr4094

Alternate gene names: 17231586

Gene position: 4932447-4933676 (Clockwise)

Preceding gene: 17231585

Following gene: 17231587

Centisome position: 76.9

GC content: 43.41

Gene sequence:

>1230_bases
ATGACCGAACAGACTAAGAGAATTGTAATTCTGGGTGGAGGCTTTGGCGGTCTCTATACAGCTTTACGTGTAAGCCAATT
ACCTTGGGAAACTCAGCAAAAACCGGAAATTGTGCTGGTAGATCAAAGCGATCGCTTTCTATTCTCCCCCTTATTGTACG
AATTACTCACCGGAGAACTGCAATCATGGGAAATTGCACCCCCTTTTATTGAACTTCTCGAAGGTACAGGTATACGTTTT
TATCAAGCAGTTGTTTCTGGTATTGATATCGACCAGCAACGGGTACATCTGCAAGATGGCCCAGAAATCCCTTATGATCG
CCTAGTTTTAACGCTAGGTGGCGAAACACCATTAGATTTAGTTCCTGGTGCCATATCCTATGCCTATCCTTTCCGTACTA
TTGCTGACACCTATCGCTTGGAAGAACGTCTGCGAGTCTTGGAAGAATCAGATGCAGAAAAAATTCGTGTAGCAATTGTT
GGTGCTGGTTATAGTGGTGTTGAGTTAGCTTGTAAGTTAGCAGATAGACTAGGAGAAAGAGGACGCTTCCGCCTAGTGGA
AATCAGCGATCAAATTTTACGCACTTCCCCAGACTTTAACCGCGAAGCAGCCAAGAAAGCTTTGGATGCAAAAGGTGTTT
TTATTGATTTAGAAACCAAAGTTGAGTCAATAGGACAAAATACCATCTCCCTAGAGTACAAAAATCAAGTAGATACCATT
CCCGTAGATTTGGTAATTTGGACTGTGGGTACAAGGGTGACAAACGTAGTGAAAAGTCTGCCCTTTAAACAGAACCAGCG
TGGTCAAATCACTAATACACCAACTCTCCAAGTTCTTGACCATCCAGACATTTTCGCCCTGGGAGACTTAGCTGACTGTA
TTGACGCTGAAGGTCAGCAAGTACCCGCTACCGCACAAGCCGCTTTTCAACAAGCAGACTACGCCGCTTGGAATATTTGG
GCTTCTCTTACTCAACGTCCCCTATTACCTTTCCGTTACCAACAATTAGGGGAGATGATGGCACTGGGTACAGATAATGC
TACCCTTACAGGTTTAGGAGTTAAATTAGATGGTTCTTTGGCTTATGTTGCCCGCCGTCTCGCCTACTTGTATAGATTAC
CAACACTAGATCATCAACTTAAAGTTGGCTTTAACTGGCTTGTACGTCCTATTATAGAAACAATTTACTCAGCAGTGGAT
GCTGTGAATGAAAAGGGTACTAGGTATTAG

Upstream 100 bases:

>100_bases
AAGACAAGTACTCAAATTGCTGGCTGATGGTCATAGAAGAAAATAAATCATTACACTGAGAGTTAGTTGCCTTATTGGGA
TAGAATCTCCCATATAATTT

Downstream 100 bases:

>100_bases
GGATTGCACTTCCTTGCTTGAACACTTTCGCGCAGGGAAGTCAATGACCAATGACTAACATTTATAATTTGCAAGCAGTT
TAATGGAAAGGCCTAAAGTT

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MTEQTKRIVILGGGFGGLYTALRVSQLPWETQQKPEIVLVDQSDRFLFSPLLYELLTGELQSWEIAPPFIELLEGTGIRF
YQAVVSGIDIDQQRVHLQDGPEIPYDRLVLTLGGETPLDLVPGAISYAYPFRTIADTYRLEERLRVLEESDAEKIRVAIV
GAGYSGVELACKLADRLGERGRFRLVEISDQILRTSPDFNREAAKKALDAKGVFIDLETKVESIGQNTISLEYKNQVDTI
PVDLVIWTVGTRVTNVVKSLPFKQNQRGQITNTPTLQVLDHPDIFALGDLADCIDAEGQQVPATAQAAFQQADYAAWNIW
ASLTQRPLLPFRYQQLGEMMALGTDNATLTGLGVKLDGSLAYVARRLAYLYRLPTLDHQLKVGFNWLVRPIIETIYSAVD
AVNEKGTRY

Sequences:

>Translated_409_residues
MTEQTKRIVILGGGFGGLYTALRVSQLPWETQQKPEIVLVDQSDRFLFSPLLYELLTGELQSWEIAPPFIELLEGTGIRF
YQAVVSGIDIDQQRVHLQDGPEIPYDRLVLTLGGETPLDLVPGAISYAYPFRTIADTYRLEERLRVLEESDAEKIRVAIV
GAGYSGVELACKLADRLGERGRFRLVEISDQILRTSPDFNREAAKKALDAKGVFIDLETKVESIGQNTISLEYKNQVDTI
PVDLVIWTVGTRVTNVVKSLPFKQNQRGQITNTPTLQVLDHPDIFALGDLADCIDAEGQQVPATAQAAFQQADYAAWNIW
ASLTQRPLLPFRYQQLGEMMALGTDNATLTGLGVKLDGSLAYVARRLAYLYRLPTLDHQLKVGFNWLVRPIIETIYSAVD
AVNEKGTRY
>Mature_408_residues
TEQTKRIVILGGGFGGLYTALRVSQLPWETQQKPEIVLVDQSDRFLFSPLLYELLTGELQSWEIAPPFIELLEGTGIRFY
QAVVSGIDIDQQRVHLQDGPEIPYDRLVLTLGGETPLDLVPGAISYAYPFRTIADTYRLEERLRVLEESDAEKIRVAIVG
AGYSGVELACKLADRLGERGRFRLVEISDQILRTSPDFNREAAKKALDAKGVFIDLETKVESIGQNTISLEYKNQVDTIP
VDLVIWTVGTRVTNVVKSLPFKQNQRGQITNTPTLQVLDHPDIFALGDLADCIDAEGQQVPATAQAAFQQADYAAWNIWA
SLTQRPLLPFRYQQLGEMMALGTDNATLTGLGVKLDGSLAYVARRLAYLYRLPTLDHQLKVGFNWLVRPIIETIYSAVDA
VNEKGTRY

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI14318424, Length=322, Percent_Identity=25.1552795031056, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787352, Length=436, Percent_Identity=31.4220183486239, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6323515, Length=458, Percent_Identity=24.0174672489083, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323794, Length=450, Percent_Identity=23.5555555555556, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320118, Length=449, Percent_Identity=22.4944320712695, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 45676; Mature: 45545

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQTKRIVILGGGFGGLYTALRVSQLPWETQQKPEIVLVDQSDRFLFSPLLYELLTGEL
CCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCC
QSWEIAPPFIELLEGTGIRFYQAVVSGIDIDQQRVHLQDGPEIPYDRLVLTLGGETPLDL
CCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCHHEEEECCCCCCCHHHEEEEECCCCCHHH
VPGAISYAYPFRTIADTYRLEERLRVLEESDAEKIRVAIVGAGYSGVELACKLADRLGER
CCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCC
GRFRLVEISDQILRTSPDFNREAAKKALDAKGVFIDLETKVESIGQNTISLEYKNQVDTI
CCEEEEEECHHHHHCCCCCCHHHHHHHHCCCCEEEEEHHHHHHCCCCEEEEEECCCCCCC
PVDLVIWTVGTRVTNVVKSLPFKQNQRGQITNTPTLQVLDHPDIFALGDLADCIDAEGQQ
CEEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEEECCHHHHHCCCCCC
VPATAQAAFQQADYAAWNIWASLTQRPLLPFRYQQLGEMMALGTDNATLTGLGVKLDGSL
CCHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCHH
AYVARRLAYLYRLPTLDHQLKVGFNWLVRPIIETIYSAVDAVNEKGTRY
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TEQTKRIVILGGGFGGLYTALRVSQLPWETQQKPEIVLVDQSDRFLFSPLLYELLTGEL
CCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCC
QSWEIAPPFIELLEGTGIRFYQAVVSGIDIDQQRVHLQDGPEIPYDRLVLTLGGETPLDL
CCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCHHEEEECCCCCCCHHHEEEEECCCCCHHH
VPGAISYAYPFRTIADTYRLEERLRVLEESDAEKIRVAIVGAGYSGVELACKLADRLGER
CCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCC
GRFRLVEISDQILRTSPDFNREAAKKALDAKGVFIDLETKVESIGQNTISLEYKNQVDTI
CCEEEEEECHHHHHCCCCCCHHHHHHHHCCCCEEEEEHHHHHHCCCCEEEEEECCCCCCC
PVDLVIWTVGTRVTNVVKSLPFKQNQRGQITNTPTLQVLDHPDIFALGDLADCIDAEGQQ
CEEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEEECCHHHHHCCCCCC
VPATAQAAFQQADYAAWNIWASLTQRPLLPFRYQQLGEMMALGTDNATLTGLGVKLDGSL
CCHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCHH
AYVARRLAYLYRLPTLDHQLKVGFNWLVRPIIETIYSAVDAVNEKGTRY
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]