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The map label for this gene is pgsA [H]

Identifier: 17231555

GI number: 17231555

Start: 4892355

End: 4892873

Strand: Reverse

Name: pgsA [H]

Synonym: all4063

Alternate gene names: 17231555

Gene position: 4892873-4892355 (Counterclockwise)

Preceding gene: 17231562

Following gene: 17231547

Centisome position: 76.29

GC content: 41.62

Gene sequence:

>519_bases
ATGACTTTACCCAACTGGATTACCTTCTCTCGTCTTCTTGGTGTGCCATTTTTGTTGTATGGTTTGTACGACTCTACATC
AAAAGCTAGGTGGGTATGTTTGGCAATTTTTTTAGTTGCTGCTTTGACTGATTGGTTAGATGGTTATCTAGCGCGAAAAC
TTAACCAAGTTAGTGATTTGGGTAAATTTCTTGATCCATTGGTGGATAAATTTTTAGTATTAGCGCCGTTATTGGTTTTG
GTGGAGTTGGGGAAAATTCCCGCTTGGGGAGTGTTTTTGATTTTAGCGCGGGAATTGGCGATCGCTGGTTGGCGCGTTAA
TCAAACGACGATTACAGGGGCGAATATTTGGGGTAAGTTGAAAACTGTGAGTCAGATATTAGCGATCGCTCTTTTAATTG
CACCTCTATCATCAGATTGGCAACAAGTATCCTTAATTGCCTTTTGGCTTTCTGTGGCTTTGACACTAATCTCTGGCGGA
ATTTATCTCTGGCCGCAAAAACTCAGTCAGGCTTCATAG

Upstream 100 bases:

>100_bases
ACTTTTGAGAGGCAGGGGAAGCAAAGAAGAATAACTATTGACTGTTGACTATGGACTAATAACTATGGACTAATAAATAA
AAACTTCCTCACCCAAATTC

Downstream 100 bases:

>100_bases
AATATATAGCCGTAGCCAAATATATTAGGACATCAAGCTAAAATAAAATCCTCATAACACAGGGCTTTCAAGTCTGTCAA
CCGTCAACAGCAACAGTTCT

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MTLPNWITFSRLLGVPFLLYGLYDSTSKARWVCLAIFLVAALTDWLDGYLARKLNQVSDLGKFLDPLVDKFLVLAPLLVL
VELGKIPAWGVFLILARELAIAGWRVNQTTITGANIWGKLKTVSQILAIALLIAPLSSDWQQVSLIAFWLSVALTLISGG
IYLWPQKLSQAS

Sequences:

>Translated_172_residues
MTLPNWITFSRLLGVPFLLYGLYDSTSKARWVCLAIFLVAALTDWLDGYLARKLNQVSDLGKFLDPLVDKFLVLAPLLVL
VELGKIPAWGVFLILARELAIAGWRVNQTTITGANIWGKLKTVSQILAIALLIAPLSSDWQQVSLIAFWLSVALTLISGG
IYLWPQKLSQAS
>Mature_171_residues
TLPNWITFSRLLGVPFLLYGLYDSTSKARWVCLAIFLVAALTDWLDGYLARKLNQVSDLGKFLDPLVDKFLVLAPLLVLV
ELGKIPAWGVFLILARELAIAGWRVNQTTITGANIWGKLKTVSQILAIALLIAPLSSDWQQVSLIAFWLSVALTLISGGI
YLWPQKLSQAS

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=174, Percent_Identity=33.9080459770115, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 19026; Mature: 18895

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPNWITFSRLLGVPFLLYGLYDSTSKARWVCLAIFLVAALTDWLDGYLARKLNQVSDL
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKFLDPLVDKFLVLAPLLVLVELGKIPAWGVFLILARELAIAGWRVNQTTITGANIWGKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHH
KTVSQILAIALLIAPLSSDWQQVSLIAFWLSVALTLISGGIYLWPQKLSQAS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEECHHHHCCCC
>Mature Secondary Structure 
TLPNWITFSRLLGVPFLLYGLYDSTSKARWVCLAIFLVAALTDWLDGYLARKLNQVSDL
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKFLDPLVDKFLVLAPLLVLVELGKIPAWGVFLILARELAIAGWRVNQTTITGANIWGKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHH
KTVSQILAIALLIAPLSSDWQQVSLIAFWLSVALTLISGGIYLWPQKLSQAS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEECHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]