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The map label for this gene is gcvT [H]

Identifier: 17231547

GI number: 17231547

Start: 4881652

End: 4882635

Strand: Reverse

Name: gcvT [H]

Synonym: all4055

Alternate gene names: 17231547

Gene position: 4882635-4881652 (Counterclockwise)

Preceding gene: 17231555

Following gene: 17231545

Centisome position: 76.13

GC content: 44.21

Gene sequence:

>984_bases
ATGCCGACATCTGCCTTAGACGGTAAAGACACAGCCGCTATCCAAGCCGCAACAGCAGAAGTTGCTGTATATGATCGCTC
CAATTGGGGACTTATCCGTGTTTCTGATGATGACCGTTTGCGGTTTTTACACAATCAAAGTACCAATGATTTCCAGAGTC
TGAAGCCAGGACAGGGCTGTGAGACAGTTATGGTGACATCTACAGCCCGGACTATAGATTTGGTGAGTAGCTATGTTCTT
AATGATGCAGTCATACTTTTAGTTTCCTCCAGTCGTCGGGAGTTTTTGCTGCAATGGCTGGATCGTTACATCTTCTTTGC
TGATAAGGTGCAGTTAACTGATATTACTGATGAAACTGCAACTTTGAGTATTATTGGCCCAGGTAGTGACGCTGTAGTAG
AAAAATTGGGTGCGGGAGAAATTATCGGTCAACCCCACGGCAATCATATTACTATCGATGGCGGTGTCGTCGCTGCGGTG
GGTAGTGGTTTGGCTTCCCCTGGCTATACGTTGATTTTGCCAGTGTCCCAAAAACAGCAAGTATGGCAGCAAATTCTCGA
CTCAGGGGCGGTAGAATTAAGCGATCGCGCTTGGGATACTTTACGCATATTACAAGGAAGACCAGCACCAGATGCAGAAT
TAACTGATGATTACAACCCGTTGGAAGTGGGTTTATGGCAGACTATTTCTTTTAGCAAGGGTTGCTATATCGGGCAAGAA
ACCATCGCTAGATTAAATACATATAAAGGTGTCAAACAACATCTTTGGGGTATCCGTCTTAACGCTCCGGCAGAAATTGG
CGATAGTATTAATATTGGTGATGAAAAAGTTGGTAAACTCACCAGTTATACAGAAACTCCTGATGGTTATTTTGGTCTAG
CTTACATTCGTAGCAAAGCTGGTGGTGTGGGTTTAAAAGTGCAGGTAGGAAACAGTGAGGGAGAAGTAGTTGCTATCCCC
TTTGTTTCTCATGAATACCCTTAA

Upstream 100 bases:

>100_bases
ACAAAATATATTTTTAGATATGTCAATTGAAATTAGGATATATCTAAAGTAATTACTTCCGTCCTTATTTAACATAAATT
AAATTTAACGCTTGACTATC

Downstream 100 bases:

>100_bases
AAAGGGGTATAGGGGTATAGGGGTGTAAATGTTTAAAACCCTTAACCCTGTGCGTAATTAATTATGTTTTCCATTACCCA
TTACCCATTACCCATCACTA

Product: glycine cleavage T-protein; aminomethyltransferase

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MPTSALDGKDTAAIQAATAEVAVYDRSNWGLIRVSDDDRLRFLHNQSTNDFQSLKPGQGCETVMVTSTARTIDLVSSYVL
NDAVILLVSSSRREFLLQWLDRYIFFADKVQLTDITDETATLSIIGPGSDAVVEKLGAGEIIGQPHGNHITIDGGVVAAV
GSGLASPGYTLILPVSQKQQVWQQILDSGAVELSDRAWDTLRILQGRPAPDAELTDDYNPLEVGLWQTISFSKGCYIGQE
TIARLNTYKGVKQHLWGIRLNAPAEIGDSINIGDEKVGKLTSYTETPDGYFGLAYIRSKAGGVGLKVQVGNSEGEVVAIP
FVSHEYP

Sequences:

>Translated_327_residues
MPTSALDGKDTAAIQAATAEVAVYDRSNWGLIRVSDDDRLRFLHNQSTNDFQSLKPGQGCETVMVTSTARTIDLVSSYVL
NDAVILLVSSSRREFLLQWLDRYIFFADKVQLTDITDETATLSIIGPGSDAVVEKLGAGEIIGQPHGNHITIDGGVVAAV
GSGLASPGYTLILPVSQKQQVWQQILDSGAVELSDRAWDTLRILQGRPAPDAELTDDYNPLEVGLWQTISFSKGCYIGQE
TIARLNTYKGVKQHLWGIRLNAPAEIGDSINIGDEKVGKLTSYTETPDGYFGLAYIRSKAGGVGLKVQVGNSEGEVVAIP
FVSHEYP
>Mature_326_residues
PTSALDGKDTAAIQAATAEVAVYDRSNWGLIRVSDDDRLRFLHNQSTNDFQSLKPGQGCETVMVTSTARTIDLVSSYVLN
DAVILLVSSSRREFLLQWLDRYIFFADKVQLTDITDETATLSIIGPGSDAVVEKLGAGEIIGQPHGNHITIDGGVVAAVG
SGLASPGYTLILPVSQKQQVWQQILDSGAVELSDRAWDTLRILQGRPAPDAELTDDYNPLEVGLWQTISFSKGCYIGQET
IARLNTYKGVKQHLWGIRLNAPAEIGDSINIGDEKVGKLTSYTETPDGYFGLAYIRSKAGGVGLKVQVGNSEGEVVAIPF
VSHEYP

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0354

COG function: function code R; Predicted aminomethyltransferase related to GcvT

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

None

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 35372; Mature: 35241

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSALDGKDTAAIQAATAEVAVYDRSNWGLIRVSDDDRLRFLHNQSTNDFQSLKPGQGC
CCCCCCCCCCCCEEEEEEEEEEEEECCCCCEEEECCCCCEEEEECCCCCCHHHCCCCCCC
ETVMVTSTARTIDLVSSYVLNDAVILLVSSSRREFLLQWLDRYIFFADKVQLTDITDETA
CEEEEECCHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHEEECEEEEEECCCCCE
TLSIIGPGSDAVVEKLGAGEIIGQPHGNHITIDGGVVAAVGSGLASPGYTLILPVSQKQQ
EEEEEECCCHHHHHHCCCCCEECCCCCCEEEECCCEEEECCCCCCCCCCEEEEECCHHHH
VWQQILDSGAVELSDRAWDTLRILQGRPAPDAELTDDYNPLEVGLWQTISFSKGCYIGQE
HHHHHHCCCCEEECCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEECHH
TIARLNTYKGVKQHLWGIRLNAPAEIGDSINIGDEKVGKLTSYTETPDGYFGLAYIRSKA
HHHHHHHHHHHHHHHCEEEECCCHHCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEECCC
GGVGLKVQVGNSEGEVVAIPFVSHEYP
CCEEEEEEECCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
PTSALDGKDTAAIQAATAEVAVYDRSNWGLIRVSDDDRLRFLHNQSTNDFQSLKPGQGC
CCCCCCCCCCCEEEEEEEEEEEEECCCCCEEEECCCCCEEEEECCCCCCHHHCCCCCCC
ETVMVTSTARTIDLVSSYVLNDAVILLVSSSRREFLLQWLDRYIFFADKVQLTDITDETA
CEEEEECCHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHEEECEEEEEECCCCCE
TLSIIGPGSDAVVEKLGAGEIIGQPHGNHITIDGGVVAAVGSGLASPGYTLILPVSQKQQ
EEEEEECCCHHHHHHCCCCCEECCCCCCEEEECCCEEEECCCCCCCCCCEEEEECCHHHH
VWQQILDSGAVELSDRAWDTLRILQGRPAPDAELTDDYNPLEVGLWQTISFSKGCYIGQE
HHHHHHCCCCEEECCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEECHH
TIARLNTYKGVKQHLWGIRLNAPAEIGDSINIGDEKVGKLTSYTETPDGYFGLAYIRSKA
HHHHHHHHHHHHHHHCEEEECCCHHCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEECCC
GGVGLKVQVGNSEGEVVAIPFVSHEYP
CCEEEEEEECCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]