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The map label for this gene is phoB [C]

Identifier: 17229732

GI number: 17229732

Start: 2691633

End: 2692223

Strand: Direct

Name: phoB [C]

Synonym: alr2240

Alternate gene names: 17229732

Gene position: 2691633-2692223 (Clockwise)

Preceding gene: 17229726

Following gene: 17229733

Centisome position: 41.97

GC content: 31.3

Gene sequence:

>591_bases
ATGACAAAAATTTTAGTAATTGAAGACCAGGAAGATATTCGTAGCATTATTGTAGAAATGCTAACTGCGGAAAATTTCTA
TGTTATGGACGCAGAAAACGGACAAGTGGGGATTACTATGCTACAAAAAGAAATTCCCGATTTGATTATCTGTGACATTG
CTATGCCTAAAATAGATGGATATGAAGTTGTTACTTGGTCACGGGAAAATCCAGAAACTGAAGCTATTCCTTTTATATTT
CTTACAGCTAAAGCCTCTCAAAATGATATTCGTCAAGGTATAGAATTAGGTGCTGATGATTATCTAGTAAAGCCATTTAC
TAGAGCAGAATTACTGGGAGCAATAACAGCTAGATTAGAGAAACAAGAAATAATTAATAGACAAACACAAAAAAGACTCA
ACACATCTTATAGTTATCTGGCATCGACAATTAGAAATGATTTAAATAATCCTCTTAACTACGTTACATCGATATCAGAG
AAACTCATCAATGACTATGAATTTATGAATCGAGAAGAAATCTTAAAAAAGATCAAAGAAATTTATAATTTAAGCAAAAA
TTTTCAGGATATAAATCTGAATAAGCGATAA

Upstream 100 bases:

>100_bases
GTCTTTCTCTAGTTGTAAACTAATTTTTAACTCCTGGGTTAAAATGTAAATATTATCAACAAAACTTTAACATAATAGAA
TACTAAAGATATCTCCAGTA

Downstream 100 bases:

>100_bases
ATCTAATCAACTAGAAAATTAAATATGAATCCTATCCAAATTTTGATAGTTGAAGATGAGCAACTAGTGGCTGATGACCT
GAGAGAAACTCTAGAATATT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MTKILVIEDQEDIRSIIVEMLTAENFYVMDAENGQVGITMLQKEIPDLIICDIAMPKIDGYEVVTWSRENPETEAIPFIF
LTAKASQNDIRQGIELGADDYLVKPFTRAELLGAITARLEKQEIINRQTQKRLNTSYSYLASTIRNDLNNPLNYVTSISE
KLINDYEFMNREEILKKIKEIYNLSKNFQDINLNKR

Sequences:

>Translated_196_residues
MTKILVIEDQEDIRSIIVEMLTAENFYVMDAENGQVGITMLQKEIPDLIICDIAMPKIDGYEVVTWSRENPETEAIPFIF
LTAKASQNDIRQGIELGADDYLVKPFTRAELLGAITARLEKQEIINRQTQKRLNTSYSYLASTIRNDLNNPLNYVTSISE
KLINDYEFMNREEILKKIKEIYNLSKNFQDINLNKR
>Mature_195_residues
TKILVIEDQEDIRSIIVEMLTAENFYVMDAENGQVGITMLQKEIPDLIICDIAMPKIDGYEVVTWSRENPETEAIPFIFL
TAKASQNDIRQGIELGADDYLVKPFTRAELLGAITARLEKQEIINRQTQKRLNTSYSYLASTIRNDLNNPLNYVTSISEK
LINDYEFMNREEILKKIKEIYNLSKNFQDINLNKR

Specific function: This Protein Is A Positive Regulator For The Phosphate Regulon. Transcription Of This Operon Is Positively Regulated By Phob And Phor When Phosphate Is Limited. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=146, Percent_Identity=31.5068493150685, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082012, Length=125, Percent_Identity=38.4, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1790860, Length=188, Percent_Identity=29.2553191489362, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1786784, Length=128, Percent_Identity=35.15625, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1786911, Length=122, Percent_Identity=34.4262295081967, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789809, Length=120, Percent_Identity=35, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI2367329, Length=128, Percent_Identity=38.28125, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788394, Length=119, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788550, Length=139, Percent_Identity=28.0575539568345, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1788191, Length=110, Percent_Identity=34.5454545454545, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787375, Length=119, Percent_Identity=30.2521008403361, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787487, Length=103, Percent_Identity=30.0970873786408, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 22687; Mature: 22556

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKILVIEDQEDIRSIIVEMLTAENFYVMDAENGQVGITMLQKEIPDLIICDIAMPKIDG
CCEEEEEECHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCC
YEVVTWSRENPETEAIPFIFLTAKASQNDIRQGIELGADDYLVKPFTRAELLGAITARLE
EEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHH
KQEIINRQTQKRLNTSYSYLASTIRNDLNNPLNYVTSISEKLINDYEFMNREEILKKIKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IYNLSKNFQDINLNKR
HHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TKILVIEDQEDIRSIIVEMLTAENFYVMDAENGQVGITMLQKEIPDLIICDIAMPKIDG
CEEEEEECHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCC
YEVVTWSRENPETEAIPFIFLTAKASQNDIRQGIELGADDYLVKPFTRAELLGAITARLE
EEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHH
KQEIINRQTQKRLNTSYSYLASTIRNDLNNPLNYVTSISEKLINDYEFMNREEILKKIKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IYNLSKNFQDINLNKR
HHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1554697 [H]