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The map label for this gene is appC [H]

Identifier: 17229503

GI number: 17229503

Start: 2406078

End: 2407019

Strand: Reverse

Name: appC [H]

Synonym: all2011

Alternate gene names: 17229503

Gene position: 2407019-2406078 (Counterclockwise)

Preceding gene: 17229504

Following gene: 17229500

Centisome position: 37.53

GC content: 46.39

Gene sequence:

>942_bases
ATGTTAAAACGTTGGCTAAATCGCACTTCCACAATACCCGAAGTACCAATTATAAGTACTATCGCTGGGCAAGAAAGCCT
CACTCAAGAAGCATGGCGAAAGTTTCGCGGTAATCGTCAGGCTATGTTGGGTGCTGTGGTATTACTGATTATCGTTTTGA
GTGTTGTGTTTGGGCCTTTGATTTACTCTGTCCCTATCAATAAAATTGATTTTGCTAAGTCCACCCTACCACCTAGTTGG
GAACATCCATTTGGGACTAATGATTTGGGTCAAGATATATTAGCCAGGATTTTGTACGGTGGCAGAATATCAATTGCTGT
GGGTGTGTTTTCGATGGTGGTGGCGATAACGTTGGGGATACTCATCGGCGCACTTTCAGGATTTTATGGCGGTTGGTTGG
ATGTGGTATTGATGCGGTTAACTGATTTGTGTTTGGCTTTACCGCGCCTACCCTTATTGTTATTGGTGATATTCTTGTTT
CGGGATGCCATCAAGGCGATCGCTGGCCCAGAACTAGGTATATTTGTCTTAGTCGTGCTAGTTATCGGCGGACTCAACTG
GATGTCTGTCGCTAGGTTAGTTAGGGCTGGGTTTTTAACTGTGCGCGAACAGGAATTTGTCACAGCCGCCCGCGCCCTCG
GTGCTTCCCCCAGACGGTTAATCTGGATTCATATTTTGCCAAATGTCATCAGTCCGGTATTGGTAGCAGCGACTCTCTCT
GTGAGTACCGCCATCGTCACGGAATCTACACTCAGCTTTTTTGGTCTGGGCTTTCCTCCTGATGTCCCGACTTGGGGGCG
GATGCTTTACGATGCACAAAACTTTTTGGAGTTTGCGCCCTATATGGTGGTTTTTCCAGGGACGGCCATATTTCTGACTG
TGCTGAGTATTAACTATATAGGTGATGGTTTACGGGATGCCCTTGATCCTCGATTGTCTTAA

Upstream 100 bases:

>100_bases
AATTACCTTTATATATGCAATTTTAATTGTGATTTTTAATCTGGTTGCCGATATTCTCTATGGTTTCTTAGATCCTCGCG
TTAAATATACAAAATAATTT

Downstream 100 bases:

>100_bases
ATTAGCTAGGTGATTGGTGATTGGTAATTGGTGATTGGGGACAAATTAACTTCTCTTTCATTACCCATTACCCATTACCC
ATTACCCATTCCCCACAATT

Product: permease protein of ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MLKRWLNRTSTIPEVPIISTIAGQESLTQEAWRKFRGNRQAMLGAVVLLIIVLSVVFGPLIYSVPINKIDFAKSTLPPSW
EHPFGTNDLGQDILARILYGGRISIAVGVFSMVVAITLGILIGALSGFYGGWLDVVLMRLTDLCLALPRLPLLLLVIFLF
RDAIKAIAGPELGIFVLVVLVIGGLNWMSVARLVRAGFLTVREQEFVTAARALGASPRRLIWIHILPNVISPVLVAATLS
VSTAIVTESTLSFFGLGFPPDVPTWGRMLYDAQNFLEFAPYMVVFPGTAIFLTVLSINYIGDGLRDALDPRLS

Sequences:

>Translated_313_residues
MLKRWLNRTSTIPEVPIISTIAGQESLTQEAWRKFRGNRQAMLGAVVLLIIVLSVVFGPLIYSVPINKIDFAKSTLPPSW
EHPFGTNDLGQDILARILYGGRISIAVGVFSMVVAITLGILIGALSGFYGGWLDVVLMRLTDLCLALPRLPLLLLVIFLF
RDAIKAIAGPELGIFVLVVLVIGGLNWMSVARLVRAGFLTVREQEFVTAARALGASPRRLIWIHILPNVISPVLVAATLS
VSTAIVTESTLSFFGLGFPPDVPTWGRMLYDAQNFLEFAPYMVVFPGTAIFLTVLSINYIGDGLRDALDPRLS
>Mature_313_residues
MLKRWLNRTSTIPEVPIISTIAGQESLTQEAWRKFRGNRQAMLGAVVLLIIVLSVVFGPLIYSVPINKIDFAKSTLPPSW
EHPFGTNDLGQDILARILYGGRISIAVGVFSMVVAITLGILIGALSGFYGGWLDVVLMRLTDLCLALPRLPLLLLVIFLF
RDAIKAIAGPELGIFVLVVLVIGGLNWMSVARLVRAGFLTVREQEFVTAARALGASPRRLIWIHILPNVISPVLVAATLS
VSTAIVTESTLSFFGLGFPPDVPTWGRMLYDAQNFLEFAPYMVVFPGTAIFLTVLSINYIGDGLRDALDPRLS

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=287, Percent_Identity=37.2822299651568, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1787498, Length=289, Percent_Identity=38.0622837370242, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1789964, Length=312, Percent_Identity=37.1794871794872, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1787760, Length=277, Percent_Identity=35.3790613718412, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1787549, Length=291, Percent_Identity=32.9896907216495, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788505, Length=249, Percent_Identity=34.5381526104418, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789889, Length=246, Percent_Identity=31.7073170731707, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34187; Mature: 34187

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRWLNRTSTIPEVPIISTIAGQESLTQEAWRKFRGNRQAMLGAVVLLIIVLSVVFGPL
CCHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IYSVPINKIDFAKSTLPPSWEHPFGTNDLGQDILARILYGGRISIAVGVFSMVVAITLGI
HHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LIGALSGFYGGWLDVVLMRLTDLCLALPRLPLLLLVIFLFRDAIKAIAGPELGIFVLVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VIGGLNWMSVARLVRAGFLTVREQEFVTAARALGASPRRLIWIHILPNVISPVLVAATLS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHH
VSTAIVTESTLSFFGLGFPPDVPTWGRMLYDAQNFLEFAPYMVVFPGTAIFLTVLSINYI
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHH
GDGLRDALDPRLS
CCHHHHHCCCCCC
>Mature Secondary Structure
MLKRWLNRTSTIPEVPIISTIAGQESLTQEAWRKFRGNRQAMLGAVVLLIIVLSVVFGPL
CCHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IYSVPINKIDFAKSTLPPSWEHPFGTNDLGQDILARILYGGRISIAVGVFSMVVAITLGI
HHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LIGALSGFYGGWLDVVLMRLTDLCLALPRLPLLLLVIFLFRDAIKAIAGPELGIFVLVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VIGGLNWMSVARLVRAGFLTVREQEFVTAARALGASPRRLIWIHILPNVISPVLVAATLS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHH
VSTAIVTESTLSFFGLGFPPDVPTWGRMLYDAQNFLEFAPYMVVFPGTAIFLTVLSINYI
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHH
GDGLRDALDPRLS
CCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]