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The map label for this gene is appB [H]

Identifier: 17229504

GI number: 17229504

Start: 2407023

End: 2408030

Strand: Reverse

Name: appB [H]

Synonym: all2012

Alternate gene names: 17229504

Gene position: 2408030-2407023 (Counterclockwise)

Preceding gene: 17229505

Following gene: 17229503

Centisome position: 37.54

GC content: 35.52

Gene sequence:

>1008_bases
GTGCTGAGTCATAAGTTAACAGGTAAGACAGATTTTGCCTCAAAAATGAATAAATATTTAATTAATCGTCTACTAGTTGC
TATCCCCACACTAATTGCTATTAGTCTGGTTATATTTACTATTTTGGCATTAGCCCCTGGTGATCCAATGGGTGAATTTG
CCCTGAATCCTTCCATCACGGCAGAGGTGCGGGAAAATATCAAAAGGTCTTTAGGATTAGACCAACCAATTCATATTCGT
TATATCAAGTGGGTGATAGCTTTTGTGCGTGGGGATATGGGCTATTCTTTCACTAGTCGCAGTCCTGTAATTGATTTAAT
TCTGCAACGTCTACCGACAACATTATGGGTAGTTGGTGCTGCTTATTTACTAGGTGCAATTTTGGCTATTCCTTTGGGTG
TGATTTCTGCCCTCAAGCGCCATACAATAATTGATCATGTTTTAACTACTTTAGTATTTTTCGGATTTTCTCTGCCAACT
TTTTTCACAGGGTTACTATTTATTATTATCTTTAGTATTCAATTGAAATGGTTACCCTTTATTTATAACAGTACATTACA
AGTAAAAGATTGGCAGAGTTTTATAGCCCAAATCCAACAATCTATTATGCCAATTTCGGTGTTAGCACTTTGGCAAACAG
CTATGCTAATGCGCTTTGTCCGTTCAGAAATTTTGGAAAATATTCACCAAGATTATGTTCGGACAGCTTATGCAAAAGGA
TTATCCAAATTTGTAGTTATTCGACGGCATATTTTACGAAATGCGTTAATTCCTGTAGTCACATTAATAGCATTGGATAT
TCCTAGTGTGTTTACAGGTGCTTTGGTAACAGAAAAAGTTTTTCGTGTTCCTGGTATTGGTGCTTTATTAATTGACTCTA
TTTATAAAAATGACACGCCAGTGGTGATGGCAATTACCTTTATATATGCAATTTTAATTGTGATTTTTAATCTGGTTGCC
GATATTCTCTATGGTTTCTTAGATCCTCGCGTTAAATATACAAAATAA

Upstream 100 bases:

>100_bases
CCCATTTGCAAATGTTGACAAAATCTGGATTTACAACGGTAGCAGTACCTTGGAAATATTATGGTTTAGCCGTTTTTGGC
GGTTGGGTGAAATAAAGTTA

Downstream 100 bases:

>100_bases
TTTATGTTAAAACGTTGGCTAAATCGCACTTCCACAATACCCGAAGTACCAATTATAAGTACTATCGCTGGGCAAGAAAG
CCTCACTCAAGAAGCATGGC

Product: permease protein of ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MLSHKLTGKTDFASKMNKYLINRLLVAIPTLIAISLVIFTILALAPGDPMGEFALNPSITAEVRENIKRSLGLDQPIHIR
YIKWVIAFVRGDMGYSFTSRSPVIDLILQRLPTTLWVVGAAYLLGAILAIPLGVISALKRHTIIDHVLTTLVFFGFSLPT
FFTGLLFIIIFSIQLKWLPFIYNSTLQVKDWQSFIAQIQQSIMPISVLALWQTAMLMRFVRSEILENIHQDYVRTAYAKG
LSKFVVIRRHILRNALIPVVTLIALDIPSVFTGALVTEKVFRVPGIGALLIDSIYKNDTPVVMAITFIYAILIVIFNLVA
DILYGFLDPRVKYTK

Sequences:

>Translated_335_residues
MLSHKLTGKTDFASKMNKYLINRLLVAIPTLIAISLVIFTILALAPGDPMGEFALNPSITAEVRENIKRSLGLDQPIHIR
YIKWVIAFVRGDMGYSFTSRSPVIDLILQRLPTTLWVVGAAYLLGAILAIPLGVISALKRHTIIDHVLTTLVFFGFSLPT
FFTGLLFIIIFSIQLKWLPFIYNSTLQVKDWQSFIAQIQQSIMPISVLALWQTAMLMRFVRSEILENIHQDYVRTAYAKG
LSKFVVIRRHILRNALIPVVTLIALDIPSVFTGALVTEKVFRVPGIGALLIDSIYKNDTPVVMAITFIYAILIVIFNLVA
DILYGFLDPRVKYTK
>Mature_335_residues
MLSHKLTGKTDFASKMNKYLINRLLVAIPTLIAISLVIFTILALAPGDPMGEFALNPSITAEVRENIKRSLGLDQPIHIR
YIKWVIAFVRGDMGYSFTSRSPVIDLILQRLPTTLWVVGAAYLLGAILAIPLGVISALKRHTIIDHVLTTLVFFGFSLPT
FFTGLLFIIIFSIQLKWLPFIYNSTLQVKDWQSFIAQIQQSIMPISVLALWQTAMLMRFVRSEILENIHQDYVRTAYAKG
LSKFVVIRRHILRNALIPVVTLIALDIPSVFTGALVTEKVFRVPGIGALLIDSIYKNDTPVVMAITFIYAILIVIFNLVA
DILYGFLDPRVKYTK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=318, Percent_Identity=36.7924528301887, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=34.5132743362832, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI1789888, Length=319, Percent_Identity=33.2288401253918, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1787497, Length=320, Percent_Identity=33.4375, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1787761, Length=321, Percent_Identity=33.3333333333333, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=28.7313432835821, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788504, Length=365, Percent_Identity=27.1232876712329, Blast_Score=130, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37678; Mature: 37678

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSHKLTGKTDFASKMNKYLINRLLVAIPTLIAISLVIFTILALAPGDPMGEFALNPSIT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
AEVRENIKRSLGLDQPIHIRYIKWVIAFVRGDMGYSFTSRSPVIDLILQRLPTTLWVVGA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AYLLGAILAIPLGVISALKRHTIIDHVLTTLVFFGFSLPTFFTGLLFIIIFSIQLKWLPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IYNSTLQVKDWQSFIAQIQQSIMPISVLALWQTAMLMRFVRSEILENIHQDYVRTAYAKG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSKFVVIRRHILRNALIPVVTLIALDIPSVFTGALVTEKVFRVPGIGALLIDSIYKNDTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
VVMAITFIYAILIVIFNLVADILYGFLDPRVKYTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLSHKLTGKTDFASKMNKYLINRLLVAIPTLIAISLVIFTILALAPGDPMGEFALNPSIT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
AEVRENIKRSLGLDQPIHIRYIKWVIAFVRGDMGYSFTSRSPVIDLILQRLPTTLWVVGA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AYLLGAILAIPLGVISALKRHTIIDHVLTTLVFFGFSLPTFFTGLLFIIIFSIQLKWLPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IYNSTLQVKDWQSFIAQIQQSIMPISVLALWQTAMLMRFVRSEILENIHQDYVRTAYAKG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSKFVVIRRHILRNALIPVVTLIALDIPSVFTGALVTEKVFRVPGIGALLIDSIYKNDTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
VVMAITFIYAILIVIFNLVADILYGFLDPRVKYTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]