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The map label for this gene is trpD [H]

Identifier: 172087685

GI number: 172087685

Start: 1135109

End: 1136116

Strand: Reverse

Name: trpD [H]

Synonym: VF_1031

Alternate gene names: 172087685

Gene position: 1136116-1135109 (Counterclockwise)

Preceding gene: 59711639

Following gene: 59711636

Centisome position: 39.21

GC content: 42.16

Gene sequence:

>1008_bases
ATGACTCAAATAGAAACCATTTTTAACAAGCTATACGATCAAGTTTCTCTTTCAGAATCAGAAAGCCAAGTTCTTTTTGA
TGCCATTATTAAAGGCGAATTAGATCCTATACTACTGACATCAGCACTCACCTGTTTAAAATTGAAAGGTGAAACACCGG
ATGAGATTACAGGGGCTGCTAAAGCATTATTAGAGAACGCAAATCCATTCCCTCAACCTGACTATGATTTTGCGGACATT
GTTGGCACCGGTGGTGACGGTTCAAATACCATCAATATTTCCACCACGGCCGCATTTGTTGCCGCAGCATGTGGGTTAAA
AATTGCGAAACATGGTAACCGTGGCGTTTCAAGTAAATCAGGATCTTCTGATCTGCTTGATTCCTTTGGCATTGATTTAG
CCATGTCTGCAGAAGACACAAGAAAAGCGGTTGATGATTTGGGTGTTGCCTTTTTGTTTGCACCGCAATACCACGGTGGT
GTTCGCCATGCGATGCCAATTCGTCAAACCATGAAAACACGCACCATCTTTAATATCCTTGGGCCTCTAATTAACCCTGC
ACGCCCCAATATTGAGCTTATGGGCGTTTACGATGAATCACTGGTTCGTCCTATTGCGGAAACCATGGTAAACATGGGAA
TGAAACGTGCTGCGGTTGTTTTTGGCTCTGGTTTAGATGAAGTTGCCATTCATGGTCCAACAACGGTGGCAGAAATTATT
GATGGTAAAATTAAAGAATACACATTAACGCCAGAAGATTTTGGACTGAATACTCATCCACTTGATTCGATTAAAGGCGG
AGAGCCAGAAGAGAATAAAGCCATTATTACGGATATTTTAACGGGTAAAGGGACAGACGCTCAATTAGGTGCTATCGCTG
TTAACGTTGCCCTATTAATGCGCTTGTTTGGCCATGAAGATCTAAAAGCTAATGCACAAAAAGCCATCGATGCCATGAAT
TCAGGTAAAGCCTTCGAATTGGTACAACAACTGGCTGCAAGAGGATAA

Upstream 100 bases:

>100_bases
GAATCCATTTTGACGACTCAAGGGGCACAACTGCTCATTAATACCTTGAATTGGGCATTAGATCTAACAGCAAAAGACAA
TAAAGAATAAGGATATTCTC

Downstream 100 bases:

>100_bases
ATGAATGACACAGCAATTGTCTGAACACATCTCAGTAGAAAATACAAAAATGGCTGAAGTGCTTGTAAAAATAGTAAAAG
ACAAAGCCATTTGGGTCGAA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTQIETIFNKLYDQVSLSESESQVLFDAIIKGELDPILLTSALTCLKLKGETPDEITGAAKALLENANPFPQPDYDFADI
VGTGGDGSNTINISTTAAFVAAACGLKIAKHGNRGVSSKSGSSDLLDSFGIDLAMSAEDTRKAVDDLGVAFLFAPQYHGG
VRHAMPIRQTMKTRTIFNILGPLINPARPNIELMGVYDESLVRPIAETMVNMGMKRAAVVFGSGLDEVAIHGPTTVAEII
DGKIKEYTLTPEDFGLNTHPLDSIKGGEPEENKAIITDILTGKGTDAQLGAIAVNVALLMRLFGHEDLKANAQKAIDAMN
SGKAFELVQQLAARG

Sequences:

>Translated_335_residues
MTQIETIFNKLYDQVSLSESESQVLFDAIIKGELDPILLTSALTCLKLKGETPDEITGAAKALLENANPFPQPDYDFADI
VGTGGDGSNTINISTTAAFVAAACGLKIAKHGNRGVSSKSGSSDLLDSFGIDLAMSAEDTRKAVDDLGVAFLFAPQYHGG
VRHAMPIRQTMKTRTIFNILGPLINPARPNIELMGVYDESLVRPIAETMVNMGMKRAAVVFGSGLDEVAIHGPTTVAEII
DGKIKEYTLTPEDFGLNTHPLDSIKGGEPEENKAIITDILTGKGTDAQLGAIAVNVALLMRLFGHEDLKANAQKAIDAMN
SGKAFELVQQLAARG
>Mature_334_residues
TQIETIFNKLYDQVSLSESESQVLFDAIIKGELDPILLTSALTCLKLKGETPDEITGAAKALLENANPFPQPDYDFADIV
GTGGDGSNTINISTTAAFVAAACGLKIAKHGNRGVSSKSGSSDLLDSFGIDLAMSAEDTRKAVDDLGVAFLFAPQYHGGV
RHAMPIRQTMKTRTIFNILGPLINPARPNIELMGVYDESLVRPIAETMVNMGMKRAAVVFGSGLDEVAIHGPTTVAEIID
GKIKEYTLTPEDFGLNTHPLDSIKGGEPEENKAIITDILTGKGTDAQLGAIAVNVALLMRLFGHEDLKANAQKAIDAMNS
GKAFELVQQLAARG

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=332, Percent_Identity=61.7469879518072, Blast_Score=402, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6320561, Length=321, Percent_Identity=34.8909657320872, Blast_Score=150, Evalue=3e-37,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 35630; Mature: 35499

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQIETIFNKLYDQVSLSESESQVLFDAIIKGELDPILLTSALTCLKLKGETPDEITGAA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCCHHHHHHH
KALLENANPFPQPDYDFADIVGTGGDGSNTINISTTAAFVAAACGLKIAKHGNRGVSSKS
HHHHHCCCCCCCCCCCHHHHEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCC
GSSDLLDSFGIDLAMSAEDTRKAVDDLGVAFLFAPQYHGGVRHAMPIRQTMKTRTIFNIL
CCHHHHHHHCCCEEECCHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
GPLINPARPNIELMGVYDESLVRPIAETMVNMGMKRAAVVFGSGLDEVAIHGPTTVAEII
HHHCCCCCCCEEEEEECHHHHHHHHHHHHHHCCHHHHHHEECCCCCCEEECCCHHHHHHH
DGKIKEYTLTPEDFGLNTHPLDSIKGGEPEENKAIITDILTGKGTDAQLGAIAVNVALLM
CCCCCEEEECHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
RLFGHEDLKANAQKAIDAMNSGKAFELVQQLAARG
HHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TQIETIFNKLYDQVSLSESESQVLFDAIIKGELDPILLTSALTCLKLKGETPDEITGAA
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCCHHHHHHH
KALLENANPFPQPDYDFADIVGTGGDGSNTINISTTAAFVAAACGLKIAKHGNRGVSSKS
HHHHHCCCCCCCCCCCHHHHEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCC
GSSDLLDSFGIDLAMSAEDTRKAVDDLGVAFLFAPQYHGGVRHAMPIRQTMKTRTIFNIL
CCHHHHHHHCCCEEECCHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
GPLINPARPNIELMGVYDESLVRPIAETMVNMGMKRAAVVFGSGLDEVAIHGPTTVAEII
HHHCCCCCCCEEEEEECHHHHHHHHHHHHHHCCHHHHHHEECCCCCCEEECCCHHHHHHH
DGKIKEYTLTPEDFGLNTHPLDSIKGGEPEENKAIITDILTGKGTDAQLGAIAVNVALLM
CCCCCEEEECHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
RLFGHEDLKANAQKAIDAMNSGKAFELVQQLAARG
HHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA