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The map label for this gene is ycbL [H]

Identifier: 170757056

GI number: 170757056

Start: 2478568

End: 2479272

Strand: Reverse

Name: ycbL [H]

Synonym: CLD_2287

Alternate gene names: 170757056

Gene position: 2479272-2478568 (Counterclockwise)

Preceding gene: 170756951

Following gene: 170754637

Centisome position: 62.64

GC content: 30.35

Gene sequence:

>705_bases
ATGGAAAAATTAAAGATATTAATTGTAGAAGATGATGTTAATATAAATAATATGATAAAGGAATCATTGATAAAGGAAGG
ATATGATATAGAGCAAGCTTTTCATGGGCTTGAAGCTGTGGAAAAATTTAAAGGTGAAAATTATCATATGGTAATTATGG
ATATTATGATGCCTGTTATGGATGGCATCGAGTCAATGAGAAGAATTAGGGAAAAAAGTAAAGTTCCAATTATAATACTT
TCTGCAAAGGGAGAAGACAGTGACAAAATAATAGGACTTGGTATGGGAGCGGATGATTACATTGTAAAACCATTTTCAGT
GCCAGAGCTTATAGCAAGAGTTAAATGTAATATAAGAAGAGCCATTTATTATAATGAAACTAAAAGTATTAAAGAAAATA
AGATATATGAATATGGTGATGTGAAATTTGATATGAATAATTACATAGTTACCAAAGGAGGAAAGGAACTTACTCTTACT
GCAAAGGAAATGAAAATTCTTAAGCTTTTCTTTGAAAATCCAAACAGAGTATTTACCAAAGTACAGATATATGACAGTGT
ATGGGGAGAAGAGTTTTTATCAGATTATAATACGGTAACAGTGCATATGAGAAGACTTAGAAGTAAAATCGAGGATGATC
CCAATAACCCTAAACTTATAGAAACTGTTTGGGGAATAGGATACAAATTAACAGGTGATAGATAA

Upstream 100 bases:

>100_bases
TATTTATATATAGGTAGCTTATATAAATAATTATAAAAATATTATGAAAGGGAAAAGTATAATAAATTTTTATTATAGAT
TTAGTATATAAGGTGATACT

Downstream 100 bases:

>100_bases
TGAATTGGATATTAATAATTATTATAATAATACTATCTATACTATTATTAAATGATAAAATAAAAACTAAAAGGATTACT
GCAAAATTAAATGAGATTCT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MEKLKILIVEDDVNINNMIKESLIKEGYDIEQAFHGLEAVEKFKGENYHMVIMDIMMPVMDGIESMRRIREKSKVPIIIL
SAKGEDSDKIIGLGMGADDYIVKPFSVPELIARVKCNIRRAIYYNETKSIKENKIYEYGDVKFDMNNYIVTKGGKELTLT
AKEMKILKLFFENPNRVFTKVQIYDSVWGEEFLSDYNTVTVHMRRLRSKIEDDPNNPKLIETVWGIGYKLTGDR

Sequences:

>Translated_234_residues
MEKLKILIVEDDVNINNMIKESLIKEGYDIEQAFHGLEAVEKFKGENYHMVIMDIMMPVMDGIESMRRIREKSKVPIIIL
SAKGEDSDKIIGLGMGADDYIVKPFSVPELIARVKCNIRRAIYYNETKSIKENKIYEYGDVKFDMNNYIVTKGGKELTLT
AKEMKILKLFFENPNRVFTKVQIYDSVWGEEFLSDYNTVTVHMRRLRSKIEDDPNNPKLIETVWGIGYKLTGDR
>Mature_234_residues
MEKLKILIVEDDVNINNMIKESLIKEGYDIEQAFHGLEAVEKFKGENYHMVIMDIMMPVMDGIESMRRIREKSKVPIIIL
SAKGEDSDKIIGLGMGADDYIVKPFSVPELIARVKCNIRRAIYYNETKSIKENKIYEYGDVKFDMNNYIVTKGGKELTLT
AKEMKILKLFFENPNRVFTKVQIYDSVWGEEFLSDYNTVTVHMRRLRSKIEDDPNNPKLIETVWGIGYKLTGDR

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=31.3304721030043, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=34.4978165938865, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=36.4035087719298, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=32.8888888888889, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=31.7391304347826, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=36.0869565217391, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1790863, Length=238, Percent_Identity=31.9327731092437, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=30.1310043668122, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=32.4675324675325, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790860, Length=235, Percent_Identity=30.2127659574468, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=28.5714285714286, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=28.3842794759825, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=27.7533039647577, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=28.9473684210526, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=34.5794392523364, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=107, Percent_Identity=35.5140186915888, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788191, Length=113, Percent_Identity=31.858407079646, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790299, Length=133, Percent_Identity=27.8195488721804, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=105, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=115, Percent_Identity=39.1304347826087, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27162; Mature: 27162

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLKILIVEDDVNINNMIKESLIKEGYDIEQAFHGLEAVEKFKGENYHMVIMDIMMPVM
CCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHH
DGIESMRRIREKSKVPIIILSAKGEDSDKIIGLGMGADDYIVKPFSVPELIARVKCNIRR
HHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCCEECCCCHHHHHHHHHHCCEE
AIYYNETKSIKENKIYEYGDVKFDMNNYIVTKGGKELTLTAKEMKILKLFFENPNRVFTK
EEEECCCCCCCCCCCEEECCEEEECCCEEEECCCCEEEEEHHHHHHHHHHHCCCCEEEEE
VQIYDSVWGEEFLSDYNTVTVHMRRLRSKIEDDPNNPKLIETVWGIGYKLTGDR
EEEHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCC
>Mature Secondary Structure
MEKLKILIVEDDVNINNMIKESLIKEGYDIEQAFHGLEAVEKFKGENYHMVIMDIMMPVM
CCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHH
DGIESMRRIREKSKVPIIILSAKGEDSDKIIGLGMGADDYIVKPFSVPELIARVKCNIRR
HHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCCEECCCCHHHHHHHHHHCCEE
AIYYNETKSIKENKIYEYGDVKFDMNNYIVTKGGKELTLTAKEMKILKLFFENPNRVFTK
EEEECCCCCCCCCCCEEECCEEEECCCEEEECCCCEEEEEHHHHHHHHHHHCCCCEEEEE
VQIYDSVWGEEFLSDYNTVTVHMRRLRSKIEDDPNNPKLIETVWGIGYKLTGDR
EEEHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]