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The map label for this gene is ycbM [H]

Identifier: 170756577

GI number: 170756577

Start: 298481

End: 299389

Strand: Direct

Name: ycbM [H]

Synonym: CLD_0526

Alternate gene names: 170756577

Gene position: 298481-299389 (Clockwise)

Preceding gene: 170757667

Following gene: 170756004

Centisome position: 7.54

GC content: 24.97

Gene sequence:

>909_bases
ATGTATTTATTAGCTATTATTTTATTTATGATTTTTATAATTATATTTTCAGTAGTAATGTGTATTAAATTATTTTCATA
TAAAAGGCAAATACGGGATATTACCAATCAGGTTAGAGAGTTTAAACATAGAAAAACAAATAAAAAGATTAATATTGAAA
TAGCAGATAAAGATATAGAAGAGCTTGCTTGTGAGGTTAATGAGTACCTAGAACTCTATAAAAGGAATGAAGAAGAAAAG
ATAGTATTTGAAAACACATTAAAACAAGGAATAGCTAATATGTCCCATGATTTAAGAACCCCATTAACTTCAATAATAGG
GTATTTAAAGCTACTTGAAAATGATGAAATAGATAAAAAAGAAGCACTGGATATACTTAAAAATAAAACTAATAAGCTAA
ATATACTTATAAATGATTTTTTTGAGTTAGCTTCAATAGAAAGTGAAGATTATGAATTAGATATGATAAAAGTAAATTTG
ACTAATATAGTGCGTGATGAAATCTTATCACTTTATGAAGCTTTTCAAGACAAAGGACTTAAACCAAAGATAAATATTTT
GGATAAACCAATTTTTATAATGAGGGATAAGGATAGTTTAGAGAGAATAATAGATAATTTACTTTCTAATACATTGAAAT
ATGCAGAAAAAGATATTGAAATAAATTTAGAAGAATCTAATGATAAAGTTATTTTAAAAATCTCAAATATATGTACAAGC
ATTGATGAAAAAGATGTATTACATATGTTCGATAGATTTTATATGGCAGATAAGGTAAGAAAAGGACAAGGAACAGGACT
TGGCCTTTCTATTGTAAAAAGTTTAATGGAAAAGATGGACGGAATCATAACCTCAAAGTTTGAACAAAATAGGGTTTCTA
TAATATGCGAATGGAAATATATAAAATAA

Upstream 100 bases:

>100_bases
AGATATTAAGTAATTCAGATAAAAAGATTATTTGATATATAAAGCATGAAGATATTAAATAATTAAGAAAAAATCTATTA
TATAAATTAGGAGAATTGAG

Downstream 100 bases:

>100_bases
TATTGTTTTATATATTCACGACCGCCCGTGAGTAGCTTAAATAGTTGGTTACAGGCAGTTGTGCTTTTTTCTACCGTGTA
TTGTTGGGAATAGGAGTTTA

Product: two component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MYLLAIILFMIFIIIFSVVMCIKLFSYKRQIRDITNQVREFKHRKTNKKINIEIADKDIEELACEVNEYLELYKRNEEEK
IVFENTLKQGIANMSHDLRTPLTSIIGYLKLLENDEIDKKEALDILKNKTNKLNILINDFFELASIESEDYELDMIKVNL
TNIVRDEILSLYEAFQDKGLKPKINILDKPIFIMRDKDSLERIIDNLLSNTLKYAEKDIEINLEESNDKVILKISNICTS
IDEKDVLHMFDRFYMADKVRKGQGTGLGLSIVKSLMEKMDGIITSKFEQNRVSIICEWKYIK

Sequences:

>Translated_302_residues
MYLLAIILFMIFIIIFSVVMCIKLFSYKRQIRDITNQVREFKHRKTNKKINIEIADKDIEELACEVNEYLELYKRNEEEK
IVFENTLKQGIANMSHDLRTPLTSIIGYLKLLENDEIDKKEALDILKNKTNKLNILINDFFELASIESEDYELDMIKVNL
TNIVRDEILSLYEAFQDKGLKPKINILDKPIFIMRDKDSLERIIDNLLSNTLKYAEKDIEINLEESNDKVILKISNICTS
IDEKDVLHMFDRFYMADKVRKGQGTGLGLSIVKSLMEKMDGIITSKFEQNRVSIICEWKYIK
>Mature_302_residues
MYLLAIILFMIFIIIFSVVMCIKLFSYKRQIRDITNQVREFKHRKTNKKINIEIADKDIEELACEVNEYLELYKRNEEEK
IVFENTLKQGIANMSHDLRTPLTSIIGYLKLLENDEIDKKEALDILKNKTNKLNILINDFFELASIESEDYELDMIKVNL
TNIVRDEILSLYEAFQDKGLKPKINILDKPIFIMRDKDSLERIIDNLLSNTLKYAEKDIEINLEESNDKVILKISNICTS
IDEKDVLHMFDRFYMADKVRKGQGTGLGLSIVKSLMEKMDGIITSKFEQNRVSIICEWKYIK

Specific function: Member of the two-component regulatory system ycbM/ycbL. Probably activates ycbL by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=257, Percent_Identity=31.9066147859922, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI145693157, Length=214, Percent_Identity=30.8411214953271, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788393, Length=250, Percent_Identity=25.2, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1786783, Length=292, Percent_Identity=23.972602739726, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=27.5862068965517, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=26.3374485596708, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=295, Percent_Identity=24.406779661017, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=203, Percent_Identity=26.1083743842365, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790346, Length=201, Percent_Identity=25.8706467661692, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=207, Percent_Identity=26.5700483091787, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87082128, Length=213, Percent_Identity=24.8826291079812, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787374, Length=288, Percent_Identity=20.1388888888889, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081816, Length=258, Percent_Identity=23.6434108527132, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 35470; Mature: 35470

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLLAIILFMIFIIIFSVVMCIKLFSYKRQIRDITNQVREFKHRKTNKKINIEIADKDIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
ELACEVNEYLELYKRNEEEKIVFENTLKQGIANMSHDLRTPLTSIIGYLKLLENDEIDKK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EALDILKNKTNKLNILINDFFELASIESEDYELDMIKVNLTNIVRDEILSLYEAFQDKGL
HHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCC
KPKINILDKPIFIMRDKDSLERIIDNLLSNTLKYAEKDIEINLEESNDKVILKISNICTS
CCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEHHHHHC
IDEKDVLHMFDRFYMADKVRKGQGTGLGLSIVKSLMEKMDGIITSKFEQNRVSIICEWKY
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
IK
CC
>Mature Secondary Structure
MYLLAIILFMIFIIIFSVVMCIKLFSYKRQIRDITNQVREFKHRKTNKKINIEIADKDIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
ELACEVNEYLELYKRNEEEKIVFENTLKQGIANMSHDLRTPLTSIIGYLKLLENDEIDKK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EALDILKNKTNKLNILINDFFELASIESEDYELDMIKVNLTNIVRDEILSLYEAFQDKGL
HHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCC
KPKINILDKPIFIMRDKDSLERIIDNLLSNTLKYAEKDIEINLEESNDKVILKISNICTS
CCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEHHHHHC
IDEKDVLHMFDRFYMADKVRKGQGTGLGLSIVKSLMEKMDGIITSKFEQNRVSIICEWKY
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
IK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]