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The map label for this gene is cheA

Identifier: 170755986

GI number: 170755986

Start: 2916615

End: 2918486

Strand: Reverse

Name: cheA

Synonym: CLD_1826

Alternate gene names: 170755986

Gene position: 2918486-2916615 (Counterclockwise)

Preceding gene: 170755806

Following gene: 170756124

Centisome position: 73.73

GC content: 29.91

Gene sequence:

>1872_bases
ATGGATACATCACAATACATGTCAATGTTCCTAGAAGAATCTATGGACAATTTACAAACATTAAATGACTCCTTACTTCA
ATTAGAACAAGAGCCAGATGATATAGATAAACTAAATGAAATATTTAGAGTTGCCCATACCATAAAAGGAATGGCGGCCA
CTATGGGCTTTAATGAGATGTCAGAGTTGACTCATAAAATGGAAGACGTACTTTCTAATTTTAGAGAAGGAGATTTAAAA
GTAACACAGAATGTAGTTACTGTACTTTTTAAATGTCTAGATACCCTAGAACAAATGGTAAATAATATATCAGAAGAGGT
AGACGAAAAGGTTCCAATAGATCACATAATAGAAGAACTAGAGAAGGCAGCAAATGGAGATATAAGTTCACAAGAAAATG
AAAAAGAGGCTGTAGAAACTATAGAGGAAAATAAAAGTGAAGGAAATTCTACCATACCACTAAATGAATATGATTTAAAT
GTTATAAAACAAGCAGAAGATAGAGGATTTAATGCTTATGAAATAAAAATAATATTAAGTGAAAATACTCTATTAAAATC
TGCAAGAGCTTTTTTAATATTTAAAAACTTAGAAGAGTATGGTGAAATAATAAAATCCTTACCTATAGCAGAAGACATAG
AAAATGAAAATTTTGATTTTGAAATAGATTTAATATACTTAACTACTAAAGGTAAAGAAGAAATTTATGATATTTTGGCA
AATATATCTGAAGTAGATAATGTTATGGTCGATAATGTAGATGTACAGTTAAAAAGGGAAGAAAAAATAGAAAGTAGAGA
AGTAAAAGAAAAAGTAAAAGAGCAAATAAATAATATAGATACAAAAAAACCAGAAGAAGAAAATACAGATAAGAAAACTA
AAGTAGAAGAAAATAAACCAAAGGCTAATAAAAGGGTAGCAAAACCAAAGGAAAATAATCATAAAAAAGCTCACCAATCC
GTAAGAGTAGATCTTGAAAGACTAGATAAATTTATGAATATGGTTTCAGAGCTTGTAATCCATAGAACTAGATTAGAACA
AATAAGTACTAATCACAAGCTAACAGATTTAAATGAAACTTTGGAACAAGTAGCAAGAACTACCTCTGACTTGCAAGATT
TGGTTATGAAAATAAGAATGCTTCCTTTAGATATAGTATTTAATAGATTCCCAAGAATGGTTAGAGACCTTTCTGTAGAG
TTAGACAAAGAAATGGAACTTATAGTACAAGGCGCGGACACAGAATTAGATAGAACAGTAATAGATGAAATTGGAGAACC
TCTAATCCATTTAATAAGAAATGCAGCAGACCATGGTGTAGAACCAAGGGAGGAAAGAGTAAAAAAAGGCAAAGATCCTA
TAGGAAAGATAAGATTAATAGCTTATCAAGAAGGAACAAAAGCTGTTATAAAAGTAGAAGATGATGGTGGCGGTGTACCT
GTTGACAAAGTAAAAGCTAAAGCAGAAAGAATAGGTATAAATACCGAGGGAATGTCAGACAATGATATAAGAAATTTAAT
ATTTGCTCAAGGATTTAGTACTAATGAAAAAGTAACAGACATATCTGGTAGAGGAGTAGGTATGGATGTAGTAAAAACTA
AAATTACTGCATTAGGTGGTACTGTAGATCTTATAAGCGAAGAAGGAAAGGGATCCTCTTTTATAATAAGACTTCCTTTA
ACGCTACAAATAATACAAGCTCTTTTAGTTGAAGTTGGAAGTGAAACTATGGCTATATCCTTAGGCTATATAGATAGAGT
AATAGATTATGAAAAAGATATAGTAAAGAAAACTAATAATAAAGAAGTTATAATATATAGAGGTAATGTAATACCATTTG
TTAGAGTAAATGAAAAACTAGGACTTCAATAA

Upstream 100 bases:

>100_bases
ACTTTTTGTAGGAGCTACAGAAAGCATTTATAATTATAAAGATTATGGTTTTGAGAAGGTGTCTACATTTATATATAGAA
AAATATAAGGGGGAAGTAAC

Downstream 100 bases:

>100_bases
TCAGAAAATGATAAAAAATACATAGTAATAGTTAAATCTGGTGAAAAAACTGTAGGACTTTTAGTAGATGGTCTTTTAGG
TCAAAAGGAAATAGTTATAA

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MDTSQYMSMFLEESMDNLQTLNDSLLQLEQEPDDIDKLNEIFRVAHTIKGMAATMGFNEMSELTHKMEDVLSNFREGDLK
VTQNVVTVLFKCLDTLEQMVNNISEEVDEKVPIDHIIEELEKAANGDISSQENEKEAVETIEENKSEGNSTIPLNEYDLN
VIKQAEDRGFNAYEIKIILSENTLLKSARAFLIFKNLEEYGEIIKSLPIAEDIENENFDFEIDLIYLTTKGKEEIYDILA
NISEVDNVMVDNVDVQLKREEKIESREVKEKVKEQINNIDTKKPEEENTDKKTKVEENKPKANKRVAKPKENNHKKAHQS
VRVDLERLDKFMNMVSELVIHRTRLEQISTNHKLTDLNETLEQVARTTSDLQDLVMKIRMLPLDIVFNRFPRMVRDLSVE
LDKEMELIVQGADTELDRTVIDEIGEPLIHLIRNAADHGVEPREERVKKGKDPIGKIRLIAYQEGTKAVIKVEDDGGGVP
VDKVKAKAERIGINTEGMSDNDIRNLIFAQGFSTNEKVTDISGRGVGMDVVKTKITALGGTVDLISEEGKGSSFIIRLPL
TLQIIQALLVEVGSETMAISLGYIDRVIDYEKDIVKKTNNKEVIIYRGNVIPFVRVNEKLGLQ

Sequences:

>Translated_623_residues
MDTSQYMSMFLEESMDNLQTLNDSLLQLEQEPDDIDKLNEIFRVAHTIKGMAATMGFNEMSELTHKMEDVLSNFREGDLK
VTQNVVTVLFKCLDTLEQMVNNISEEVDEKVPIDHIIEELEKAANGDISSQENEKEAVETIEENKSEGNSTIPLNEYDLN
VIKQAEDRGFNAYEIKIILSENTLLKSARAFLIFKNLEEYGEIIKSLPIAEDIENENFDFEIDLIYLTTKGKEEIYDILA
NISEVDNVMVDNVDVQLKREEKIESREVKEKVKEQINNIDTKKPEEENTDKKTKVEENKPKANKRVAKPKENNHKKAHQS
VRVDLERLDKFMNMVSELVIHRTRLEQISTNHKLTDLNETLEQVARTTSDLQDLVMKIRMLPLDIVFNRFPRMVRDLSVE
LDKEMELIVQGADTELDRTVIDEIGEPLIHLIRNAADHGVEPREERVKKGKDPIGKIRLIAYQEGTKAVIKVEDDGGGVP
VDKVKAKAERIGINTEGMSDNDIRNLIFAQGFSTNEKVTDISGRGVGMDVVKTKITALGGTVDLISEEGKGSSFIIRLPL
TLQIIQALLVEVGSETMAISLGYIDRVIDYEKDIVKKTNNKEVIIYRGNVIPFVRVNEKLGLQ
>Mature_623_residues
MDTSQYMSMFLEESMDNLQTLNDSLLQLEQEPDDIDKLNEIFRVAHTIKGMAATMGFNEMSELTHKMEDVLSNFREGDLK
VTQNVVTVLFKCLDTLEQMVNNISEEVDEKVPIDHIIEELEKAANGDISSQENEKEAVETIEENKSEGNSTIPLNEYDLN
VIKQAEDRGFNAYEIKIILSENTLLKSARAFLIFKNLEEYGEIIKSLPIAEDIENENFDFEIDLIYLTTKGKEEIYDILA
NISEVDNVMVDNVDVQLKREEKIESREVKEKVKEQINNIDTKKPEEENTDKKTKVEENKPKANKRVAKPKENNHKKAHQS
VRVDLERLDKFMNMVSELVIHRTRLEQISTNHKLTDLNETLEQVARTTSDLQDLVMKIRMLPLDIVFNRFPRMVRDLSVE
LDKEMELIVQGADTELDRTVIDEIGEPLIHLIRNAADHGVEPREERVKKGKDPIGKIRLIAYQEGTKAVIKVEDDGGGVP
VDKVKAKAERIGINTEGMSDNDIRNLIFAQGFSTNEKVTDISGRGVGMDVVKTKITALGGTVDLISEEGKGSSFIIRLPL
TLQIIQALLVEVGSETMAISLGYIDRVIDYEKDIVKKTNNKEVIIYRGNVIPFVRVNEKLGLQ

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Membrane (Potential). Note=It is not known whether CheA is actually membrane bound although CheA has two regions at the C-terminal end with the potential to be transmembrane regions [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=626, Percent_Identity=32.4281150159744, Blast_Score=293, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70804; Mature: 70804

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTSQYMSMFLEESMDNLQTLNDSLLQLEQEPDDIDKLNEIFRVAHTIKGMAATMGFNEM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
SELTHKMEDVLSNFREGDLKVTQNVVTVLFKCLDTLEQMVNNISEEVDEKVPIDHIIEEL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
EKAANGDISSQENEKEAVETIEENKSEGNSTIPLNEYDLNVIKQAEDRGFNAYEIKIILS
HHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEE
ENTLLKSARAFLIFKNLEEYGEIIKSLPIAEDIENENFDFEIDLIYLTTKGKEEIYDILA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEEECCCHHHHHHHHH
NISEVDNVMVDNVDVQLKREEKIESREVKEKVKEQINNIDTKKPEEENTDKKTKVEENKP
HHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCC
KANKRVAKPKENNHKKAHQSVRVDLERLDKFMNMVSELVIHRTRLEQISTNHKLTDLNET
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LEQVARTTSDLQDLVMKIRMLPLDIVFNRFPRMVRDLSVELDKEMELIVQGADTELDRTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCHHHHHH
IDEIGEPLIHLIRNAADHGVEPREERVKKGKDPIGKIRLIAYQEGTKAVIKVEDDGGGVP
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEEECCCEEEEEEECCCCCCC
VDKVKAKAERIGINTEGMSDNDIRNLIFAQGFSTNEKVTDISGRGVGMDVVKTKITALGG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCCC
TVDLISEEGKGSSFIIRLPLTLQIIQALLVEVGSETMAISLGYIDRVIDYEKDIVKKTNN
HHEECCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCC
KEVIIYRGNVIPFVRVNEKLGLQ
CEEEEEECCEEEEEEECHHCCCC
>Mature Secondary Structure
MDTSQYMSMFLEESMDNLQTLNDSLLQLEQEPDDIDKLNEIFRVAHTIKGMAATMGFNEM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
SELTHKMEDVLSNFREGDLKVTQNVVTVLFKCLDTLEQMVNNISEEVDEKVPIDHIIEEL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
EKAANGDISSQENEKEAVETIEENKSEGNSTIPLNEYDLNVIKQAEDRGFNAYEIKIILS
HHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEE
ENTLLKSARAFLIFKNLEEYGEIIKSLPIAEDIENENFDFEIDLIYLTTKGKEEIYDILA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEEECCCHHHHHHHHH
NISEVDNVMVDNVDVQLKREEKIESREVKEKVKEQINNIDTKKPEEENTDKKTKVEENKP
HHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCC
KANKRVAKPKENNHKKAHQSVRVDLERLDKFMNMVSELVIHRTRLEQISTNHKLTDLNET
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LEQVARTTSDLQDLVMKIRMLPLDIVFNRFPRMVRDLSVELDKEMELIVQGADTELDRTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCHHHHHH
IDEIGEPLIHLIRNAADHGVEPREERVKKGKDPIGKIRLIAYQEGTKAVIKVEDDGGGVP
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEEECCCEEEEEEECCCCCCC
VDKVKAKAERIGINTEGMSDNDIRNLIFAQGFSTNEKVTDISGRGVGMDVVKTKITALGG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCCC
TVDLISEEGKGSSFIIRLPLTLQIIQALLVEVGSETMAISLGYIDRVIDYEKDIVKKTNN
HHEECCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCC
KEVIIYRGNVIPFVRVNEKLGLQ
CEEEEEECCEEEEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1938941; 9384377 [H]