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The map label for this gene is tdk

Identifier: 170755962

GI number: 170755962

Start: 173956

End: 174531

Strand: Direct

Name: tdk

Synonym: CLD_0650

Alternate gene names: 170755962

Gene position: 173956-174531 (Clockwise)

Preceding gene: 170754540

Following gene: 170757760

Centisome position: 4.39

GC content: 33.51

Gene sequence:

>576_bases
ATGTATGGTCCCAAAGATCATGGCTGGATTGAAGTAGTAGCAGGCCCTATGTATAGTGGAAAAACGGAAGAATTAATAAG
ACGAATAAGAAGAGCTGAAATTGCAAAGCAAAAAGTTCAAGTTTTTAAACCTGAAATAGATAACAGATATAGTAAACAAG
ATGTTGTGTCTCATGCAGGAGATAAAATTCAGTCAGTACCAGTTAAAAGTAGTAAAGAAATATTAGAAAAACTTTTAGAT
GATACAGATGTGATAGGTATAGATGAAGCACAATTTTTTGATGATTTTTTAGTTGAAATAGTAAGTAAAATAGCTAATAA
TAATAGAAGGGTTATTTGTGCAGGACTAGATATGGATTTTAAGGGAGAACCCTTTGGTCCAATGCCTAAACTTATGGCTA
TAGCAGAATTTGTAGATAAAATACAAGCTGTATGTATGGTTTGTAATAATCCAGCTACAAGAACCCAAAGACTTATAAAT
GGAAAGCCAGCAAAGAAATCTGACCCAGTAGTATTAATAGGGGCACAAGAGTCTTATGAAGCTAGATGTAGGAAGTGTCA
TCGTGTTCCAAGATAA

Upstream 100 bases:

>100_bases
GAATTAAATAATTATATGTAAATTTTACCTATAATAAATTCTTTATTATAATAATTAGTTTTGATAAAATATACTTGTTT
ATTAAAATGGAGGTGTTTTT

Downstream 100 bases:

>100_bases
GTAATGAGGTGATTAAGTGGGGAGAAGTACTAACGTTGGGGGACAAGCAGTTTTAGAAGGGGTAATGATGAGAGGAAAAA
ATGGTATAGCAACGGCAGTT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MYGPKDHGWIEVVAGPMYSGKTEELIRRIRRAEIAKQKVQVFKPEIDNRYSKQDVVSHAGDKIQSVPVKSSKEILEKLLD
DTDVIGIDEAQFFDDFLVEIVSKIANNNRRVICAGLDMDFKGEPFGPMPKLMAIAEFVDKIQAVCMVCNNPATRTQRLIN
GKPAKKSDPVVLIGAQESYEARCRKCHRVPR

Sequences:

>Translated_191_residues
MYGPKDHGWIEVVAGPMYSGKTEELIRRIRRAEIAKQKVQVFKPEIDNRYSKQDVVSHAGDKIQSVPVKSSKEILEKLLD
DTDVIGIDEAQFFDDFLVEIVSKIANNNRRVICAGLDMDFKGEPFGPMPKLMAIAEFVDKIQAVCMVCNNPATRTQRLIN
GKPAKKSDPVVLIGAQESYEARCRKCHRVPR
>Mature_191_residues
MYGPKDHGWIEVVAGPMYSGKTEELIRRIRRAEIAKQKVQVFKPEIDNRYSKQDVVSHAGDKIQSVPVKSSKEILEKLLD
DTDVIGIDEAQFFDDFLVEIVSKIANNNRRVICAGLDMDFKGEPFGPMPKLMAIAEFVDKIQAVCMVCNNPATRTQRLIN
GKPAKKSDPVVLIGAQESYEARCRKCHRVPR

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family

Homologues:

Organism=Homo sapiens, GI164698438, Length=183, Percent_Identity=39.8907103825137, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17543396, Length=187, Percent_Identity=33.6898395721925, Blast_Score=96, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KITH_CLOB1 (A7FQF9)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001382543.1
- ProteinModelPortal:   A7FQF9
- SMR:   A7FQF9
- STRING:   A7FQF9
- GeneID:   5395865
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_0172
- eggNOG:   COG1435
- HOGENOM:   HBG522108
- OMA:   VITGPMY
- ProtClustDB:   PRK04296
- BioCyc:   CBOT441770:CLB_0172-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00124
- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634
- PANTHER:   PTHR11441
- PIRSF:   PIRSF035805

Pfam domain/function: PF00265 TK

EC number: =2.7.1.21

Molecular weight: Translated: 21545; Mature: 21545

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: ACT_SITE 89-89

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGPKDHGWIEVVAGPMYSGKTEELIRRIRRAEIAKQKVQVFKPEIDNRYSKQDVVSHAG
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC
DKIQSVPVKSSKEILEKLLDDTDVIGIDEAQFFDDFLVEIVSKIANNNRRVICAGLDMDF
CHHHCCCCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
KGEPFGPMPKLMAIAEFVDKIQAVCMVCNNPATRTQRLINGKPAKKSDPVVLIGAQESYE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEECCCCHH
ARCRKCHRVPR
HHHHHHHCCCC
>Mature Secondary Structure
MYGPKDHGWIEVVAGPMYSGKTEELIRRIRRAEIAKQKVQVFKPEIDNRYSKQDVVSHAG
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC
DKIQSVPVKSSKEILEKLLDDTDVIGIDEAQFFDDFLVEIVSKIANNNRRVICAGLDMDF
CHHHCCCCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
KGEPFGPMPKLMAIAEFVDKIQAVCMVCNNPATRTQRLINGKPAKKSDPVVLIGAQESYE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEECCCCHH
ARCRKCHRVPR
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA