Click here to switch to the map view.

The map label for this gene is adhB [H]

Identifier: 170755815

GI number: 170755815

Start: 1595303

End: 1596502

Strand: Direct

Name: adhB [H]

Synonym: CLD_3113

Alternate gene names: 170755815

Gene position: 1595303-1596502 (Clockwise)

Preceding gene: 170754252

Following gene: 170756653

Centisome position: 40.3

GC content: 33.33

Gene sequence:

>1200_bases
ATGTGGGAATCTAAAATGGCTATAAATGAGATAAGAGAGATAAGATCCAAGACCACTGTTTATTTAGGGGTAGGAGCAAT
AGAAAAAATATATGATATAGCATCTAATTTGAAAAATATGAATATAGATAAGGTACTTATTGTCACAGGAAGAGGGGCTT
ACAAAAAAACTGGGGCTTGGGAGTATGTTGAAAAAGCTTTGGAAAAGGAAAATATAACCTATATTTTATATAATGAAGTT
ACACCAAATCCAACTGTAGATCAAGTAGACGAGGCTGCTAGAATGGGAAATGAATTAGGTGCAAAGGCGGTAATAGGTAT
AGGAGGAGGAAGTCCTATAGATGCAGCTAAAAGTGTAGCAATACTTTTAGAATATAAAGATAAAACTGCAAGGGATATAT
ATGAATTTAAATTTACCCCAGAAAAAGCAGCTCCAGTTATTGCAATAAATTTAACTCATGGAACAGGCACAGAAGGAGAT
AGATTTGCAGTAGTCAGTATTCCAGAAAAAGAATACAAGCCAGCCATAGCCTATGGTTGTATATATCCTTTATATGCTAT
AGATGACCCACAACTTATGGTTAAACTACCAATACACCAAACTTGCTATGTATCAGTGGACGCTATAAATCATGTAGTAG
AGGCTTCCACAAGTAAAGTAGCAAGTCCATATACCATATTATTAGCAAAGGAAACCGTGAGACTAGTTTCTAGATATTTG
CCACAGGCATTGCAACATCCAGGGGATTTAACAGCTAGATATTATTTAACATATGCTTCTTTAATTGCAGGTATATGTTT
TGATAATGGATTACTTCATTTTACTCATGCTTTAGAACATCCATTAAGTGGAGTGAAACCAGATTTATCTCATGGTTTAG
GATTAGGAATATTATTACCTTCTGTAATAAAGGAAATATATCCATCAGTATCTGAGGTTTTAGCAGATATTTTATCACCA
ATAGTTTGTGGGTTAGAAGGAAATCCAGGAGAAGCTGAAATAGCAGCTAAAGGTATAGAAAAATGGTTATATAGTATAGG
TATTACAGAAAAATTAACAGATTTAGGATTTAAAGAAAATGATGTGGAAAAATTGACAAAGTTAGCTTTTGAAACACCAA
GCTTAGACTTATTGTTGAGTATGGCTCCAATAGATGCAGATGAAAAGGTCGTTAGTAATATATTTAGAAATTCTCTTTAA

Upstream 100 bases:

>100_bases
ATAATTGTAAAAACTATTGTGTTTTGTTAAAAAAATAACTATAATATAAATATGATAGTTTATTTACATTATTTATATAA
ATTTAAGGGGGTATTTATAA

Downstream 100 bases:

>100_bases
ATTTAATATAAATAATAATCATAGAAAAGCTTTTATATAGTGTATATGAAAGCAAAAAAATTAATTTAAAATAAAACTAC
CTAAAAGATGATTAATATGG

Product: alcohol dehydrogenase, iron-containing

Products: NA

Alternate protein names: Alcohol dehydrogenase II; ADH II [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MWESKMAINEIREIRSKTTVYLGVGAIEKIYDIASNLKNMNIDKVLIVTGRGAYKKTGAWEYVEKALEKENITYILYNEV
TPNPTVDQVDEAARMGNELGAKAVIGIGGGSPIDAAKSVAILLEYKDKTARDIYEFKFTPEKAAPVIAINLTHGTGTEGD
RFAVVSIPEKEYKPAIAYGCIYPLYAIDDPQLMVKLPIHQTCYVSVDAINHVVEASTSKVASPYTILLAKETVRLVSRYL
PQALQHPGDLTARYYLTYASLIAGICFDNGLLHFTHALEHPLSGVKPDLSHGLGLGILLPSVIKEIYPSVSEVLADILSP
IVCGLEGNPGEAEIAAKGIEKWLYSIGITEKLTDLGFKENDVEKLTKLAFETPSLDLLLSMAPIDADEKVVSNIFRNSL

Sequences:

>Translated_399_residues
MWESKMAINEIREIRSKTTVYLGVGAIEKIYDIASNLKNMNIDKVLIVTGRGAYKKTGAWEYVEKALEKENITYILYNEV
TPNPTVDQVDEAARMGNELGAKAVIGIGGGSPIDAAKSVAILLEYKDKTARDIYEFKFTPEKAAPVIAINLTHGTGTEGD
RFAVVSIPEKEYKPAIAYGCIYPLYAIDDPQLMVKLPIHQTCYVSVDAINHVVEASTSKVASPYTILLAKETVRLVSRYL
PQALQHPGDLTARYYLTYASLIAGICFDNGLLHFTHALEHPLSGVKPDLSHGLGLGILLPSVIKEIYPSVSEVLADILSP
IVCGLEGNPGEAEIAAKGIEKWLYSIGITEKLTDLGFKENDVEKLTKLAFETPSLDLLLSMAPIDADEKVVSNIFRNSL
>Mature_399_residues
MWESKMAINEIREIRSKTTVYLGVGAIEKIYDIASNLKNMNIDKVLIVTGRGAYKKTGAWEYVEKALEKENITYILYNEV
TPNPTVDQVDEAARMGNELGAKAVIGIGGGSPIDAAKSVAILLEYKDKTARDIYEFKFTPEKAAPVIAINLTHGTGTEGD
RFAVVSIPEKEYKPAIAYGCIYPLYAIDDPQLMVKLPIHQTCYVSVDAINHVVEASTSKVASPYTILLAKETVRLVSRYL
PQALQHPGDLTARYYLTYASLIAGICFDNGLLHFTHALEHPLSGVKPDLSHGLGLGILLPSVIKEIYPSVSEVLADILSP
IVCGLEGNPGEAEIAAKGIEKWLYSIGITEKLTDLGFKENDVEKLTKLAFETPSLDLLLSMAPIDADEKVVSNIFRNSL

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=411, Percent_Identity=23.1143552311436, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI48994951, Length=380, Percent_Identity=30.7894736842105, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI87082107, Length=349, Percent_Identity=28.3667621776504, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1787493, Length=365, Percent_Identity=29.8630136986301, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1789163, Length=380, Percent_Identity=26.8421052631579, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1789386, Length=367, Percent_Identity=25.0681198910082, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17537053, Length=426, Percent_Identity=24.8826291079812, Blast_Score=128, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6321181, Length=372, Percent_Identity=31.989247311828, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24657991, Length=423, Percent_Identity=23.8770685579196, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 43660; Mature: 43660

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWESKMAINEIREIRSKTTVYLGVGAIEKIYDIASNLKNMNIDKVLIVTGRGAYKKTGAW
CCCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCH
EYVEKALEKENITYILYNEVTPNPTVDQVDEAARMGNELGAKAVIGIGGGSPIDAAKSVA
HHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCHHCCCEEEEECCCCCCCHHHCCEE
ILLEYKDKTARDIYEFKFTPEKAAPVIAINLTHGTGTEGDRFAVVSIPEKEYKPAIAYGC
EEEEECCCCHHHHHHEEECCCCCCCEEEEEEECCCCCCCCEEEEEECCHHHCCCHHHHHH
IYPLYAIDDPQLMVKLPIHQTCYVSVDAINHVVEASTSKVASPYTILLAKETVRLVSRYL
HHHEEECCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHH
PQALQHPGDLTARYYLTYASLIAGICFDNGLLHFTHALEHPLSGVKPDLSHGLGLGILLP
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHCCCHHHHHH
SVIKEIYPSVSEVLADILSPIVCGLEGNPGEAEIAAKGIEKWLYSIGITEKLTDLGFKEN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
DVEKLTKLAFETPSLDLLLSMAPIDADEKVVSNIFRNSL
HHHHHHHHHHCCCCHHEEEEECCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MWESKMAINEIREIRSKTTVYLGVGAIEKIYDIASNLKNMNIDKVLIVTGRGAYKKTGAW
CCCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCH
EYVEKALEKENITYILYNEVTPNPTVDQVDEAARMGNELGAKAVIGIGGGSPIDAAKSVA
HHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCHHCCCEEEEECCCCCCCHHHCCEE
ILLEYKDKTARDIYEFKFTPEKAAPVIAINLTHGTGTEGDRFAVVSIPEKEYKPAIAYGC
EEEEECCCCHHHHHHEEECCCCCCCEEEEEEECCCCCCCCEEEEEECCHHHCCCHHHHHH
IYPLYAIDDPQLMVKLPIHQTCYVSVDAINHVVEASTSKVASPYTILLAKETVRLVSRYL
HHHEEECCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHH
PQALQHPGDLTARYYLTYASLIAGICFDNGLLHFTHALEHPLSGVKPDLSHGLGLGILLP
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHCCCHHHHHH
SVIKEIYPSVSEVLADILSPIVCGLEGNPGEAEIAAKGIEKWLYSIGITEKLTDLGFKEN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
DVEKLTKLAFETPSLDLLLSMAPIDADEKVVSNIFRNSL
HHHHHHHHHHCCCCHHEEEEECCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3584063; 2308827; 2935393 [H]