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The map label for this gene is yclK [H]

Identifier: 170755348

GI number: 170755348

Start: 902049

End: 903311

Strand: Direct

Name: yclK [H]

Synonym: CLD_3779

Alternate gene names: 170755348

Gene position: 902049-903311 (Clockwise)

Preceding gene: 170754600

Following gene: 170755601

Centisome position: 22.79

GC content: 22.72

Gene sequence:

>1263_bases
TTGTTAAAATATTTTAGAAATCCTGAAATTAAAGAATTAACTTTTAAATTTAGCATAATATTTATTCTATTTGCTATATT
AACTACAATTTTTATAAAAGCAGAACTTAATAAATTAAATAAAGATTACATAAATCAAAACACCTTAATAGTAGGAAATA
TTTTATCAAAGCATCCAGAATTAGAAGATGAAGTAATACTTTCTTTAAATAGTAATAAGGATGCAAGATATAATGAAGAA
AAAAATTATAAAATAGGAAAAAAAGTCTTAGAAAAATATTCTTATGATGAAAATTTAGATATTTATAAAAATCCAATATT
AAATAATTTTAGTATGAATTTTATATATAGAATCATAATTTATTTTGCTTTAGCTATTTTTATTATATATATCATAATAT
ATGATAAGTTTAAGTATTTTTATAAAAAAGCAGAAATTTTTACTGAAGCCTCAGAAGATATAATGGAGGGACATTTTAGT
AAGTTTATAGATGAAAATAAAGAAGGAGATTTTTATATTCTTTCTTCTAAATTTAATTTAATGTCAAACAGATTAGAGGA
ATCTTTATTAAACTTAAAAAAAGAAAAAATATTTTTAAAAAACATAATATCAGATATTTCTCATCAATTAAAAACACCAC
TATCCTCTTTAATAATGTTTAATGAATTAATGAAGGATGAAAATATGCCAATAGAAGATAGAAAAAATTTTTTAAAACTT
AGCGATGAACAATTAAGAAGAATGGAATGGCTTATTATAAATCTTTTAAAAATAGGCAGACTAGAGGCTGGAGTAGTGGA
ATTTAGAAGAGAAAATAATCCTTTGTATGTTACGGTAAACAAAGCATTAGCAGGTCTTAGTGAGAAAGCTAAAGAAAAAT
CACAACATGTAATAGTTGATATAGATGAAGATGTATATTTTAAGCATGATATGGATTGGACAGCAGAAGCTATTTCCAAT
ATTATAAAAAATTCTATAGAACATACAAATAATTATGGACAAATAAAAATAAGTTGTGAAGAAACACCAATATCCTTAAC
TATAAGTATAAAAGATAACGGAGAAGGAATACCAGAAAAATTGCAAAATAAAATATTTGAAAGATTTTATAAAGGAGAAA
ACTCAGTTAATCCTTCTAGTATAGGAATAGGGCTTTCTCTTACCAAATCTATAATAGAATCTCAAAATGGAAGTATAATT
GTAGAAAGTGAAATGGGAGAAGGAACGGAATTTATAATAACATTCTTAAAAACTATAGTATAA

Upstream 100 bases:

>100_bases
ACTCAGTGCAAAGTGGGTTGTGGAATTTTCAGTAGATAGTTACTACATAAATATTTAATTAATTTTTACAAATTAATTTA
GAATACTAAGGGGGATAATT

Downstream 100 bases:

>100_bases
AAGATATAAGAGATATTAAAATTAAATCTATTTTAGATATTTTTAAGTGAAATAGTAAAATTTAATAGTGAAGATGGTTC
ATTCTTACTTAGAATTTGAT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MLKYFRNPEIKELTFKFSIIFILFAILTTIFIKAELNKLNKDYINQNTLIVGNILSKHPELEDEVILSLNSNKDARYNEE
KNYKIGKKVLEKYSYDENLDIYKNPILNNFSMNFIYRIIIYFALAIFIIYIIIYDKFKYFYKKAEIFTEASEDIMEGHFS
KFIDENKEGDFYILSSKFNLMSNRLEESLLNLKKEKIFLKNIISDISHQLKTPLSSLIMFNELMKDENMPIEDRKNFLKL
SDEQLRRMEWLIINLLKIGRLEAGVVEFRRENNPLYVTVNKALAGLSEKAKEKSQHVIVDIDEDVYFKHDMDWTAEAISN
IIKNSIEHTNNYGQIKISCEETPISLTISIKDNGEGIPEKLQNKIFERFYKGENSVNPSSIGIGLSLTKSIIESQNGSII
VESEMGEGTEFIITFLKTIV

Sequences:

>Translated_420_residues
MLKYFRNPEIKELTFKFSIIFILFAILTTIFIKAELNKLNKDYINQNTLIVGNILSKHPELEDEVILSLNSNKDARYNEE
KNYKIGKKVLEKYSYDENLDIYKNPILNNFSMNFIYRIIIYFALAIFIIYIIIYDKFKYFYKKAEIFTEASEDIMEGHFS
KFIDENKEGDFYILSSKFNLMSNRLEESLLNLKKEKIFLKNIISDISHQLKTPLSSLIMFNELMKDENMPIEDRKNFLKL
SDEQLRRMEWLIINLLKIGRLEAGVVEFRRENNPLYVTVNKALAGLSEKAKEKSQHVIVDIDEDVYFKHDMDWTAEAISN
IIKNSIEHTNNYGQIKISCEETPISLTISIKDNGEGIPEKLQNKIFERFYKGENSVNPSSIGIGLSLTKSIIESQNGSII
VESEMGEGTEFIITFLKTIV
>Mature_420_residues
MLKYFRNPEIKELTFKFSIIFILFAILTTIFIKAELNKLNKDYINQNTLIVGNILSKHPELEDEVILSLNSNKDARYNEE
KNYKIGKKVLEKYSYDENLDIYKNPILNNFSMNFIYRIIIYFALAIFIIYIIIYDKFKYFYKKAEIFTEASEDIMEGHFS
KFIDENKEGDFYILSSKFNLMSNRLEESLLNLKKEKIFLKNIISDISHQLKTPLSSLIMFNELMKDENMPIEDRKNFLKL
SDEQLRRMEWLIINLLKIGRLEAGVVEFRRENNPLYVTVNKALAGLSEKAKEKSQHVIVDIDEDVYFKHDMDWTAEAISN
IIKNSIEHTNNYGQIKISCEETPISLTISIKDNGEGIPEKLQNKIFERFYKGENSVNPSSIGIGLSLTKSIIESQNGSII
VESEMGEGTEFIITFLKTIV

Specific function: Could be member of the two-component regulatory system yclK/yclJ. Potentially phosphorylates yclJ [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=216, Percent_Identity=28.2407407407407, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788393, Length=264, Percent_Identity=21.969696969697, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1789149, Length=219, Percent_Identity=26.9406392694064, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788713, Length=236, Percent_Identity=22.8813559322034, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787374, Length=216, Percent_Identity=24.0740740740741, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786783, Length=247, Percent_Identity=24.2914979757085, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790861, Length=231, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=22.0883534136546, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082128, Length=213, Percent_Identity=26.7605633802817, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=19.5744680851064, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=24.4813278008299, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI145693157, Length=218, Percent_Identity=24.3119266055046, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1788279, Length=203, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48984; Mature: 48984

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKYFRNPEIKELTFKFSIIFILFAILTTIFIKAELNKLNKDYINQNTLIVGNILSKHPE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCC
LEDEVILSLNSNKDARYNEEKNYKIGKKVLEKYSYDENLDIYKNPILNNFSMNFIYRIII
CCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHCCCCCCCCHHHHHHHHHH
YFALAIFIIYIIIYDKFKYFYKKAEIFTEASEDIMEGHFSKFIDENKEGDFYILSSKFNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHH
MSNRLEESLLNLKKEKIFLKNIISDISHQLKTPLSSLIMFNELMKDENMPIEDRKNFLKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
SDEQLRRMEWLIINLLKIGRLEAGVVEFRRENNPLYVTVNKALAGLSEKAKEKSQHVIVD
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEHHHHHCHHHHHHHCCCEEEEE
IDEDVYFKHDMDWTAEAISNIIKNSIEHTNNYGQIKISCEETPISLTISIKDNGEGIPEK
ECCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCCCCCCHH
LQNKIFERFYKGENSVNPSSIGIGLSLTKSIIESQNGSIIVESEMGEGTEFIITFLKTIV
HHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MLKYFRNPEIKELTFKFSIIFILFAILTTIFIKAELNKLNKDYINQNTLIVGNILSKHPE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCC
LEDEVILSLNSNKDARYNEEKNYKIGKKVLEKYSYDENLDIYKNPILNNFSMNFIYRIII
CCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHCCCCCCCCHHHHHHHHHH
YFALAIFIIYIIIYDKFKYFYKKAEIFTEASEDIMEGHFSKFIDENKEGDFYILSSKFNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHH
MSNRLEESLLNLKKEKIFLKNIISDISHQLKTPLSSLIMFNELMKDENMPIEDRKNFLKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
SDEQLRRMEWLIINLLKIGRLEAGVVEFRRENNPLYVTVNKALAGLSEKAKEKSQHVIVD
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEHHHHHCHHHHHHHCCCEEEEE
IDEDVYFKHDMDWTAEAISNIIKNSIEHTNNYGQIKISCEETPISLTISIKDNGEGIPEK
ECCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCCCCCCHH
LQNKIFERFYKGENSVNPSSIGIGLSLTKSIIESQNGSIIVESEMGEGTEFIITFLKTIV
HHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]