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The map label for this gene is walR [H]

Identifier: 170754600

GI number: 170754600

Start: 901183

End: 901896

Strand: Direct

Name: walR [H]

Synonym: CLD_3780

Alternate gene names: 170754600

Gene position: 901183-901896 (Clockwise)

Preceding gene: 170757012

Following gene: 170755348

Centisome position: 22.77

GC content: 27.87

Gene sequence:

>714_bases
GTGACAAAAATATTATTAGTAGAAGATGATATGGCCTTAGCTATTGGAGTGGAATATACATTAAAACAAGAAAATTATGA
AGTTAAAAGAGCTAAAAATTTAAAAGAGGCTAGAGAGATTTTAAAAGAAGAGGAGTTAGATTTAATTTTATTAGATTTAA
TGTTACCAGATGGAAGTGGATATGATTTTTGTAGTGAAGTAAGAGAAGAAAGTCTAATTCCAGTAATATTTATGACTGCC
TGTGATGAAGAAGCTAATGTGGTTTTAGGATTAGACATGGGAGGCGATGACTATATAACAAAACCCATTAGAATAAGAGA
ACTTTTATCTAGAATAAATGCGGTTTTGAGAAGAAGGACTAAAGAAGCAGAATTAAAAAATAAGAATATAAAAGAAAATG
ATGTAAAAAATAATAAAATAATTTCCAAGGACATAATAATAGAGCCTCTAAAAGCAAAAGTTTTCAAAGGAGAGGAAGAA
ATTTTATTAACAGCAGGGGAATATAAATTACTTTTAATATTATTAGAAAACAAAGGGAATGTGTTATCTAGGAATATTTT
ATTAGAAAAAATTTGGGATGTGGATGGAAGTTTTGTAGATGGAAACACATTAAATGTTTATATAAAAAGGTTAAGAGAAA
AAATAGAGGAAGATTCTAAAAAACCTAAATATATAGAAACTGTAAGAGGTATAGGCTATAGGTGGAGTGAGTAA

Upstream 100 bases:

>100_bases
AGAAATAGGTTCTTTTTTTATACTAAAATGTTAAATTATTTTTATTTTAAATAACTATAGTATAAATTATAATTAAATAA
GTAATGTTAGGGGGGATTTT

Downstream 100 bases:

>100_bases
AATTGGTTTATGAGAGTGTAAAGCAATCTGTGTAAACTCCACTTAAAATCTAACTCAGTGCAAAGTGGGTTGTGGAATTT
TCAGTAGATAGTTACTACAT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTKILLVEDDMALAIGVEYTLKQENYEVKRAKNLKEAREILKEEELDLILLDLMLPDGSGYDFCSEVREESLIPVIFMTA
CDEEANVVLGLDMGGDDYITKPIRIRELLSRINAVLRRRTKEAELKNKNIKENDVKNNKIISKDIIIEPLKAKVFKGEEE
ILLTAGEYKLLLILLENKGNVLSRNILLEKIWDVDGSFVDGNTLNVYIKRLREKIEEDSKKPKYIETVRGIGYRWSE

Sequences:

>Translated_237_residues
MTKILLVEDDMALAIGVEYTLKQENYEVKRAKNLKEAREILKEEELDLILLDLMLPDGSGYDFCSEVREESLIPVIFMTA
CDEEANVVLGLDMGGDDYITKPIRIRELLSRINAVLRRRTKEAELKNKNIKENDVKNNKIISKDIIIEPLKAKVFKGEEE
ILLTAGEYKLLLILLENKGNVLSRNILLEKIWDVDGSFVDGNTLNVYIKRLREKIEEDSKKPKYIETVRGIGYRWSE
>Mature_236_residues
TKILLVEDDMALAIGVEYTLKQENYEVKRAKNLKEAREILKEEELDLILLDLMLPDGSGYDFCSEVREESLIPVIFMTAC
DEEANVVLGLDMGGDDYITKPIRIRELLSRINAVLRRRTKEAELKNKNIKENDVKNNKIISKDIIIEPLKAKVFKGEEEI
LLTAGEYKLLLILLENKGNVLSRNILLEKIWDVDGSFVDGNTLNVYIKRLREKIEEDSKKPKYIETVRGIGYRWSE

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=236, Percent_Identity=35.5932203389831, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1786599, Length=237, Percent_Identity=36.7088607594937, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=36.6379310344828, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=34.3347639484979, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=32.3275862068966, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=34.051724137931, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789402, Length=236, Percent_Identity=32.6271186440678, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=31.6017316017316, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082012, Length=232, Percent_Identity=31.4655172413793, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790863, Length=242, Percent_Identity=30.5785123966942, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1787375, Length=238, Percent_Identity=30.2521008403361, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=30.7359307359307, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=30.9012875536481, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=29.1139240506329, Blast_Score=98, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27333; Mature: 27202

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKILLVEDDMALAIGVEYTLKQENYEVKRAKNLKEAREILKEEELDLILLDLMLPDGSG
CCEEEEEECCCEEEEEEEEEEECCCCHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCC
YDFCSEVREESLIPVIFMTACDEEANVVLGLDMGGDDYITKPIRIRELLSRINAVLRRRT
CHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
KEAELKNKNIKENDVKNNKIISKDIIIEPLKAKVFKGEEEILLTAGEYKLLLILLENKGN
HHHHHHCCCCCCCCCCCCEEECHHHEEECHHHHHCCCCCEEEEEECCEEEEEEEEECCCC
VLSRNILLEKIWDVDGSFVDGNTLNVYIKRLREKIEEDSKKPKYIETVRGIGYRWSE
EEHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TKILLVEDDMALAIGVEYTLKQENYEVKRAKNLKEAREILKEEELDLILLDLMLPDGSG
CEEEEEECCCEEEEEEEEEEECCCCHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCC
YDFCSEVREESLIPVIFMTACDEEANVVLGLDMGGDDYITKPIRIRELLSRINAVLRRRT
CHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
KEAELKNKNIKENDVKNNKIISKDIIIEPLKAKVFKGEEEILLTAGEYKLLLILLENKGN
HHHHHHCCCCCCCCCCCCEEECHHHEEECHHHHHCCCCCEEEEEECCEEEEEEEEECCCC
VLSRNILLEKIWDVDGSFVDGNTLNVYIKRLREKIEEDSKKPKYIETVRGIGYRWSE
EEHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA