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The map label for this gene is bcd

Identifier: 170755246

GI number: 170755246

Start: 3475906

End: 3477045

Strand: Reverse

Name: bcd

Synonym: CLD_1332

Alternate gene names: 170755246

Gene position: 3477045-3475906 (Counterclockwise)

Preceding gene: 170754683

Following gene: 170754881

Centisome position: 87.84

GC content: 33.16

Gene sequence:

>1140_bases
ATGGAATTTGGTTTATCACAAGAACAAAAGCTTGTTAAGCAGATGCTAATGGAATTTGTAGAAAATGAAGTGGAACCAAT
AGCTGCTGATATAGATAAAACAGAGAGATATCCAATTGAAACAGTAGAAAAAATGGCTAAGTATGGAATAATGGGAATGC
CATTTCCAAAGGAATACGGTGGAGCTGGTACTGATTATTTAAGCTATGTTATAGCAGTAGAAGAACTTGCAAAAGAATGT
GCAACTACATCTGTTATTTTATCAGCACATACATCTTTATGTTGCGCTCCAATATTTGAATTTGGGACAGAAGAGCAAAA
GAAAAAATATTTACCAGATCTTTTAAGCGGTAAAAAAATAGGTGCTTTTGGTTTAACAGAACCTAATGCTGGTACAGATG
CATCTGCTCAACAAAGTGTAGCTGTTTTAGAAGGAGATCATTATATATTAAATGGATCAAAAATATTTATAACTAATGGT
GGAGCAGCAGATACATTTGTAATATTTGCTATGACAGATAGAAGTAAGGGCGTTAAAGGAATTTCTGCATTTATATTAGA
AAAAGAAATGTCTGGATTTAGCGTTGGTAAAACAGAAGATAAAATGGGAATAAGAGCATCATCCACTACTGAACTTATAT
TTGAAGATGTAAAAGTTCCGAAAGAAAATTTACTTGGTAAAGAAGGAAAAGGATTTGGTATAGCCATGAAAACTTTAGAT
GGCGGAAGAATTGGAATAGCAGCTCAAGCATTAGGAATAGCAGAAGGAGCTTTAGATCACGCTATTGCATATATGAAAGA
AAGAAAACAATTCGGTAAAAATCTTACTAAATTTCAAGGCTTACAATGGTATATAGCAGATATGAAAGTGAGAGTAGATG
CTGCTAAATATCTTGTTTACAAAGCAGCATGGAAAAAATCTGCAGGAGAAAATTACACAATGGATGCAGCTGAAGCTAAA
CTGTATGCAGCTGAAGCAGCTATGTATGTAACAAATAAATCTCTTCAAATATTGGGGGGATATGGATATACTAAAGATTA
TCCATTAGAAAGAATGTTAAGAGATGCTAGAATAACTGAAATATATGAAGGGACTTCAGAAGTTCAAAAAATGGTTATAG
CTAGTAGTTTATTACACTAG

Upstream 100 bases:

>100_bases
TTAATGATGCAATTAAATATAATACAAATTTTTTATTATGATTTTAATATTAAAGCTTTATAGCTAAAATAAAGTTTCAG
AAATAATAGGGGGATTAAAT

Downstream 100 bases:

>100_bases
GAGGAGTTTTATATGAATATAGTTGTTTGTTTGAAACAAGTACCAGATACAAATGAAGTTAAGATAGATCCCATAAAAGG
AACTTTAATAAGAGAAGGAG

Product: butyryl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MEFGLSQEQKLVKQMLMEFVENEVEPIAADIDKTERYPIETVEKMAKYGIMGMPFPKEYGGAGTDYLSYVIAVEELAKEC
ATTSVILSAHTSLCCAPIFEFGTEEQKKKYLPDLLSGKKIGAFGLTEPNAGTDASAQQSVAVLEGDHYILNGSKIFITNG
GAADTFVIFAMTDRSKGVKGISAFILEKEMSGFSVGKTEDKMGIRASSTTELIFEDVKVPKENLLGKEGKGFGIAMKTLD
GGRIGIAAQALGIAEGALDHAIAYMKERKQFGKNLTKFQGLQWYIADMKVRVDAAKYLVYKAAWKKSAGENYTMDAAEAK
LYAAEAAMYVTNKSLQILGGYGYTKDYPLERMLRDARITEIYEGTSEVQKMVIASSLLH

Sequences:

>Translated_379_residues
MEFGLSQEQKLVKQMLMEFVENEVEPIAADIDKTERYPIETVEKMAKYGIMGMPFPKEYGGAGTDYLSYVIAVEELAKEC
ATTSVILSAHTSLCCAPIFEFGTEEQKKKYLPDLLSGKKIGAFGLTEPNAGTDASAQQSVAVLEGDHYILNGSKIFITNG
GAADTFVIFAMTDRSKGVKGISAFILEKEMSGFSVGKTEDKMGIRASSTTELIFEDVKVPKENLLGKEGKGFGIAMKTLD
GGRIGIAAQALGIAEGALDHAIAYMKERKQFGKNLTKFQGLQWYIADMKVRVDAAKYLVYKAAWKKSAGENYTMDAAEAK
LYAAEAAMYVTNKSLQILGGYGYTKDYPLERMLRDARITEIYEGTSEVQKMVIASSLLH
>Mature_379_residues
MEFGLSQEQKLVKQMLMEFVENEVEPIAADIDKTERYPIETVEKMAKYGIMGMPFPKEYGGAGTDYLSYVIAVEELAKEC
ATTSVILSAHTSLCCAPIFEFGTEEQKKKYLPDLLSGKKIGAFGLTEPNAGTDASAQQSVAVLEGDHYILNGSKIFITNG
GAADTFVIFAMTDRSKGVKGISAFILEKEMSGFSVGKTEDKMGIRASSTTELIFEDVKVPKENLLGKEGKGFGIAMKTLD
GGRIGIAAQALGIAEGALDHAIAYMKERKQFGKNLTKFQGLQWYIADMKVRVDAAKYLVYKAAWKKSAGENYTMDAAEAK
LYAAEAAMYVTNKSLQILGGYGYTKDYPLERMLRDARITEIYEGTSEVQKMVIASSLLH

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=49.3333333333333, Blast_Score=378, Evalue=1e-105,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=42.0911528150134, Blast_Score=313, Evalue=2e-85,
Organism=Homo sapiens, GI226958412, Length=378, Percent_Identity=40.7407407407407, Blast_Score=306, Evalue=3e-83,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=42.0588235294118, Blast_Score=284, Evalue=1e-76,
Organism=Homo sapiens, GI7656849, Length=377, Percent_Identity=38.7267904509284, Blast_Score=276, Evalue=2e-74,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=37.6, Blast_Score=269, Evalue=4e-72,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=37.6, Blast_Score=268, Evalue=5e-72,
Organism=Homo sapiens, GI21361497, Length=365, Percent_Identity=42.1917808219178, Blast_Score=268, Evalue=6e-72,
Organism=Homo sapiens, GI76496475, Length=374, Percent_Identity=36.8983957219251, Blast_Score=239, Evalue=2e-63,
Organism=Homo sapiens, GI4557235, Length=374, Percent_Identity=36.8983957219251, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=34.4827586206897, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI4503943, Length=379, Percent_Identity=29.8153034300792, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI7669494, Length=365, Percent_Identity=30.4109589041096, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI48976061, Length=397, Percent_Identity=27.7078085642317, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI211971008, Length=397, Percent_Identity=27.7078085642317, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI38505218, Length=358, Percent_Identity=27.0949720670391, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1786223, Length=379, Percent_Identity=29.5514511873351, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=29.9212598425197, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI87082384, Length=284, Percent_Identity=24.2957746478873, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081702, Length=299, Percent_Identity=23.7458193979933, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508101, Length=370, Percent_Identity=41.3513513513514, Blast_Score=315, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17506239, Length=370, Percent_Identity=41.6216216216216, Blast_Score=312, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=39.3139841688654, Blast_Score=286, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=39.5287958115183, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=37.2703412073491, Blast_Score=273, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=38.0577427821522, Blast_Score=270, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=37.4005305039788, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71990804, Length=294, Percent_Identity=41.8367346938776, Blast_Score=253, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71985184, Length=383, Percent_Identity=38.1201044386423, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI32563615, Length=229, Percent_Identity=44.9781659388646, Blast_Score=217, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI17534353, Length=375, Percent_Identity=32, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71982178, Length=272, Percent_Identity=38.2352941176471, Blast_Score=204, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI71985192, Length=330, Percent_Identity=37.5757575757576, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17505929, Length=366, Percent_Identity=31.4207650273224, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17551932, Length=365, Percent_Identity=31.5068493150685, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17531909, Length=237, Percent_Identity=35.4430379746835, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17562446, Length=336, Percent_Identity=28.8690476190476, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17531913, Length=176, Percent_Identity=32.9545454545455, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI86563381, Length=265, Percent_Identity=26.7924528301887, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI86563383, Length=265, Percent_Identity=26.7924528301887, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17540912, Length=359, Percent_Identity=23.9554317548747, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356377, Length=374, Percent_Identity=48.1283422459893, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=43.8502673796791, Blast_Score=333, Evalue=1e-91,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=38.8739946380697, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI21355753, Length=382, Percent_Identity=39.2670157068063, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=37.5661375661376, Blast_Score=275, Evalue=4e-74,
Organism=Drosophila melanogaster, GI281363737, Length=385, Percent_Identity=37.4025974025974, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI19920834, Length=381, Percent_Identity=28.6089238845144, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24652780, Length=352, Percent_Identity=22.1590909090909, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 41508; Mature: 41508

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFGLSQEQKLVKQMLMEFVENEVEPIAADIDKTERYPIETVEKMAKYGIMGMPFPKEYG
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHC
GAGTDYLSYVIAVEELAKECATTSVILSAHTSLCCAPIFEFGTEEQKKKYLPDLLSGKKI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHCCCCC
GAFGLTEPNAGTDASAQQSVAVLEGDHYILNGSKIFITNGGAADTFVIFAMTDRSKGVKG
CCCCCCCCCCCCCCCHHCCEEEEECCEEEEECCEEEEECCCCCCEEEEEEEECCCCCCCH
ISAFILEKEMSGFSVGKTEDKMGIRASSTTELIFEDVKVPKENLLGKEGKGFGIAMKTLD
HHHHHHHHHCCCCCCCCCCHHCCCCCCCHHHHHHHHHCCCHHHCCCCCCCCCEEEEEECC
GGRIGIAAQALGIAEGALDHAIAYMKERKQFGKNLTKFQGLQWYIADMKVRVDAAKYLVY
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEEEEEEHHHHHHHH
KAAWKKSAGENYTMDAAEAKLYAAEAAMYVTNKSLQILGGYGYTKDYPLERMLRDARITE
HHHHHHCCCCCCEECHHHHHHHHHHHEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHH
IYEGTSEVQKMVIASSLLH
HHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEFGLSQEQKLVKQMLMEFVENEVEPIAADIDKTERYPIETVEKMAKYGIMGMPFPKEYG
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHC
GAGTDYLSYVIAVEELAKECATTSVILSAHTSLCCAPIFEFGTEEQKKKYLPDLLSGKKI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHCCCCC
GAFGLTEPNAGTDASAQQSVAVLEGDHYILNGSKIFITNGGAADTFVIFAMTDRSKGVKG
CCCCCCCCCCCCCCCHHCCEEEEECCEEEEECCEEEEECCCCCCEEEEEEEECCCCCCCH
ISAFILEKEMSGFSVGKTEDKMGIRASSTTELIFEDVKVPKENLLGKEGKGFGIAMKTLD
HHHHHHHHHCCCCCCCCCCHHCCCCCCCHHHHHHHHHCCCHHHCCCCCCCCCEEEEEECC
GGRIGIAAQALGIAEGALDHAIAYMKERKQFGKNLTKFQGLQWYIADMKVRVDAAKYLVY
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEEEEEEHHHHHHHH
KAAWKKSAGENYTMDAAEAKLYAAEAAMYVTNKSLQILGGYGYTKDYPLERMLRDARITE
HHHHHHCCCCCCEECHHHHHHHHHHHEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHH
IYEGTSEVQKMVIASSLLH
HHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]