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The map label for this gene is rfbC

Identifier: 170755117

GI number: 170755117

Start: 2877407

End: 2877976

Strand: Reverse

Name: rfbC

Synonym: CLD_1864

Alternate gene names: 170755117

Gene position: 2877976-2877407 (Counterclockwise)

Preceding gene: 170757117

Following gene: 170755661

Centisome position: 72.71

GC content: 29.82

Gene sequence:

>570_bases
ATGGGACAATTTAAGTTTACGAAAACTCCTATAGAAGACTTATATGTAATTGAACCAAAAGTTTTTAGTGATCCTAGAGG
ATATTTTATGGAAACACATAATTATGAAGATTTTAAAACCGCTGGATTAGACATGGTTTTTGTTCAGGATAATCAATCTA
AATCTAAAAAAGGTGTACTAAGAGGGTTACATTTTCAAAAAAAACATCCTCAAGGTAAGCTTGTTAGAGTGATAAAGGGA
GAGGTTTTTGATGTGGCAGTGGATATAAGAGAAAATTCATCTACCTTTGGAAAGTGGTATGGAGTTATTTTATCAGAAGA
GAATAAAAAGCAGTTTTATATACCAGGAGGTTTTGCTCATGGTTTTTTAGTTTTATCAGATGAAGCAGAATTTTATTATA
AATGTACGGATTTTTATCACCCAGAAGATGAAGGTGGTATCATTTGGAATGACCCAACTATTAGCATAGTGTGGCCTTTT
GAAAAAATTAAAGATGCAAATATCTTATTATCAGAAAAAGATAGAAAATGGACAATACTAGAACATAATTATAATTTTTA
TAACATTTAA

Upstream 100 bases:

>100_bases
AATGGTATTTAAGTAATAAAGATTGGATGGAAAACATTATAACAGATAACTATCAGAGTTATTATAAAAAAATGTATGGA
GAGAATTAGGAGGAGATTTT

Downstream 100 bases:

>100_bases
TGGTTTGTATAGATGAGAAATAATAAAGGGCCAAGCAATTATGTATAAAATAATAGGGACATGAGCATTAATAGCTTTCA
AATAGCTATTGATGCTTATT

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MGQFKFTKTPIEDLYVIEPKVFSDPRGYFMETHNYEDFKTAGLDMVFVQDNQSKSKKGVLRGLHFQKKHPQGKLVRVIKG
EVFDVAVDIRENSSTFGKWYGVILSEENKKQFYIPGGFAHGFLVLSDEAEFYYKCTDFYHPEDEGGIIWNDPTISIVWPF
EKIKDANILLSEKDRKWTILEHNYNFYNI

Sequences:

>Translated_189_residues
MGQFKFTKTPIEDLYVIEPKVFSDPRGYFMETHNYEDFKTAGLDMVFVQDNQSKSKKGVLRGLHFQKKHPQGKLVRVIKG
EVFDVAVDIRENSSTFGKWYGVILSEENKKQFYIPGGFAHGFLVLSDEAEFYYKCTDFYHPEDEGGIIWNDPTISIVWPF
EKIKDANILLSEKDRKWTILEHNYNFYNI
>Mature_188_residues
GQFKFTKTPIEDLYVIEPKVFSDPRGYFMETHNYEDFKTAGLDMVFVQDNQSKSKKGVLRGLHFQKKHPQGKLVRVIKGE
VFDVAVDIRENSSTFGKWYGVILSEENKKQFYIPGGFAHGFLVLSDEAEFYYKCTDFYHPEDEGGIIWNDPTISIVWPFE
KIKDANILLSEKDRKWTILEHNYNFYNI

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=176, Percent_Identity=55.1136363636364, Blast_Score=192, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17550412, Length=169, Percent_Identity=49.7041420118343, Blast_Score=145, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 22155; Mature: 22024

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQFKFTKTPIEDLYVIEPKVFSDPRGYFMETHNYEDFKTAGLDMVFVQDNQSKSKKGVL
CCCCCCCCCCCCCEEEECCEECCCCCCCEEECCCCCCHHHCCEEEEEEECCCCCCHHHHH
RGLHFQKKHPQGKLVRVIKGEVFDVAVDIRENSSTFGKWYGVILSEENKKQFYIPGGFAH
HCCCCCCCCCCCEEEEEECCCEEEEEEEEECCCCCCEEEEEEEEECCCCEEEEECCCCCC
GFLVLSDEAEFYYKCTDFYHPEDEGGIIWNDPTISIVWPFEKIKDANILLSEKDRKWTIL
EEEEEECCCEEEEEEECCCCCCCCCCEEECCCEEEEEECHHHCCCCEEEEECCCCEEEEE
EHNYNFYNI
ECCCEEEEC
>Mature Secondary Structure 
GQFKFTKTPIEDLYVIEPKVFSDPRGYFMETHNYEDFKTAGLDMVFVQDNQSKSKKGVL
CCCCCCCCCCCCEEEECCEECCCCCCCEEECCCCCCHHHCCEEEEEEECCCCCCHHHHH
RGLHFQKKHPQGKLVRVIKGEVFDVAVDIRENSSTFGKWYGVILSEENKKQFYIPGGFAH
HCCCCCCCCCCCEEEEEECCCEEEEEEEEECCCCCCEEEEEEEEECCCCEEEEECCCCCC
GFLVLSDEAEFYYKCTDFYHPEDEGGIIWNDPTISIVWPFEKIKDANILLSEKDRKWTIL
EEEEEECCCEEEEEEECCCCCCCCCCEEECCCEEEEEECHHHCCCCEEEEECCCCEEEEE
EHNYNFYNI
ECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463; 10827167 [H]