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The map label for this gene is baeS [H]

Identifier: 170754560

GI number: 170754560

Start: 2056760

End: 2058220

Strand: Reverse

Name: baeS [H]

Synonym: CLD_2701

Alternate gene names: 170754560

Gene position: 2058220-2056760 (Counterclockwise)

Preceding gene: 170754678

Following gene: 170755766

Centisome position: 52.0

GC content: 26.15

Gene sequence:

>1461_bases
ATGAAAAAAGCATCCTTAAAAACACAAACTATAAGTACTTTTCTATTAATTATATTTTTAAGTATGGTATGTACAATAAC
TACTATAGGAGTTTATTTTTATATTATGTATTTTGGAAAAGATCCTATGCTAAGGCCAAATAACTATTATCAGAAACAGT
CAGATAAAATTCAACAGTTTATCGTTAGTAAGGGAGAAGATATATTAGAGGATAAAAATAGATTAGAACTTGAAAATTTA
GTTCCCCAAAAAGGTATAGGATATCAAATTACAGATCTAGAGGGTAAAATTATATATGGAAATGAAAAAGAGAGAATAAT
AAAGAATAAAAAACAGTTGATAGAGTCAATAAATAAAACAGATATTGATAATCTTGATAGAGCTAGCGTTTTTGGATCAA
AGGTTAAAAGGTATATACCTATAGTGGATAGTGATTCCAATGTGAAAGGCGCCGCTATAATTAAATACAATATTGATACA
AGTGTTAAAGAAGATAAAAATGAAAAAATAGTTCATGTATTTCAAGTATTCTTACCATTCTCTCCTTTTGTATATATAAT
TATTTTTACAATTATTTTCACAAGAAAGCTAATTAAAAGTATTCAGCATCCAATAAATGCAATAATAGATGCTTCAAATA
AAATAAAGGAGAAGGATTTAAATTTTGAAATAAATTATAAAAGCAATAATGAGCTAGGAAAATTAGTTTCTTCTTTTGAA
GAGATGAAAAATGCTTTAAAAGAATCACTAAATAAACAATGGATTATGGAGGAAGACAGAAAAGAAATAATAAAAGCCAT
AGCTCATGATTTGAAAACTCCTATTACTGTTATTCAAGGACATGTAGAGGTACTTATGGAAGGGGGAGTTAAAGATCCTA
TTAGAGTAGAAAAATATTTAAATATTATAAAAGCTAATACAGAGAGAATGGGAAGGCTTATTTCAGACATGAATCTCACA
TCAGAAATAGAGAATAAAAATTTTGATTTAGTTCCTGTAAAGGTAGATATAATTGAATTCTTAGAAAAAAAACAACAGGA
TTATAAAGTGCTATGTAAGGACAAAAATATAGAATTTAAATTATTTTTAGAAAAGAATTTTAATTTAAACAAGGAATTTT
CTATAGATGCTGAAAGACTAGAGCAAATACTAGATAATATAATATCTAATGCCATAAGGTATACACCTGATGGAAAATCT
ATAATTACTAAAGTAAAAATACATAATAATATTATAAAATTTATTGTGGAAGACGAAGGAACAGGTTTTAGTGATAAGGA
ATTATGCTATATTTTTGAAAAATTCTATAGAGGTGATAGTTCAAGATCTAAAGAGAAAGGTCACTCTGGATTGGGAATGT
ACATTGTAAGAATTTTAGTAGAAAAGCATAATGGTTGGATTGTAGCAGAAAATAAAGAAAAAGGCGGAGCTAGAATAGAA
TTTGTTATAAAAGAAATATAA

Upstream 100 bases:

>100_bases
ATATAAAAAAGATAAGAGCAAAGTTCATAAAAAGGAATGCATCTCTTAATCATATAGCTACGGTATGGGGAGTAGGTTAT
AGATGGGAGAAAAATAAAAT

Downstream 100 bases:

>100_bases
AGATGTTGAATATTTTGGTATAGAACCAGGTCTTTGAGTTAACTTGTACAAGCTGCAGATGATTTAAAAGAATTATATTA
GAAAATATTTAAAGGCTGTA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MKKASLKTQTISTFLLIIFLSMVCTITTIGVYFYIMYFGKDPMLRPNNYYQKQSDKIQQFIVSKGEDILEDKNRLELENL
VPQKGIGYQITDLEGKIIYGNEKERIIKNKKQLIESINKTDIDNLDRASVFGSKVKRYIPIVDSDSNVKGAAIIKYNIDT
SVKEDKNEKIVHVFQVFLPFSPFVYIIIFTIIFTRKLIKSIQHPINAIIDASNKIKEKDLNFEINYKSNNELGKLVSSFE
EMKNALKESLNKQWIMEEDRKEIIKAIAHDLKTPITVIQGHVEVLMEGGVKDPIRVEKYLNIIKANTERMGRLISDMNLT
SEIENKNFDLVPVKVDIIEFLEKKQQDYKVLCKDKNIEFKLFLEKNFNLNKEFSIDAERLEQILDNIISNAIRYTPDGKS
IITKVKIHNNIIKFIVEDEGTGFSDKELCYIFEKFYRGDSSRSKEKGHSGLGMYIVRILVEKHNGWIVAENKEKGGARIE
FVIKEI

Sequences:

>Translated_486_residues
MKKASLKTQTISTFLLIIFLSMVCTITTIGVYFYIMYFGKDPMLRPNNYYQKQSDKIQQFIVSKGEDILEDKNRLELENL
VPQKGIGYQITDLEGKIIYGNEKERIIKNKKQLIESINKTDIDNLDRASVFGSKVKRYIPIVDSDSNVKGAAIIKYNIDT
SVKEDKNEKIVHVFQVFLPFSPFVYIIIFTIIFTRKLIKSIQHPINAIIDASNKIKEKDLNFEINYKSNNELGKLVSSFE
EMKNALKESLNKQWIMEEDRKEIIKAIAHDLKTPITVIQGHVEVLMEGGVKDPIRVEKYLNIIKANTERMGRLISDMNLT
SEIENKNFDLVPVKVDIIEFLEKKQQDYKVLCKDKNIEFKLFLEKNFNLNKEFSIDAERLEQILDNIISNAIRYTPDGKS
IITKVKIHNNIIKFIVEDEGTGFSDKELCYIFEKFYRGDSSRSKEKGHSGLGMYIVRILVEKHNGWIVAENKEKGGARIE
FVIKEI
>Mature_486_residues
MKKASLKTQTISTFLLIIFLSMVCTITTIGVYFYIMYFGKDPMLRPNNYYQKQSDKIQQFIVSKGEDILEDKNRLELENL
VPQKGIGYQITDLEGKIIYGNEKERIIKNKKQLIESINKTDIDNLDRASVFGSKVKRYIPIVDSDSNVKGAAIIKYNIDT
SVKEDKNEKIVHVFQVFLPFSPFVYIIIFTIIFTRKLIKSIQHPINAIIDASNKIKEKDLNFEINYKSNNELGKLVSSFE
EMKNALKESLNKQWIMEEDRKEIIKAIAHDLKTPITVIQGHVEVLMEGGVKDPIRVEKYLNIIKANTERMGRLISDMNLT
SEIENKNFDLVPVKVDIIEFLEKKQQDYKVLCKDKNIEFKLFLEKNFNLNKEFSIDAERLEQILDNIISNAIRYTPDGKS
IITKVKIHNNIIKFIVEDEGTGFSDKELCYIFEKFYRGDSSRSKEKGHSGLGMYIVRILVEKHNGWIVAENKEKGGARIE
FVIKEI

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=287, Percent_Identity=25.7839721254355, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=30, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786783, Length=297, Percent_Identity=26.5993265993266, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787894, Length=281, Percent_Identity=25.2669039145907, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790861, Length=249, Percent_Identity=27.710843373494, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790346, Length=281, Percent_Identity=25.6227758007117, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788713, Length=252, Percent_Identity=25.3968253968254, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI48994928, Length=226, Percent_Identity=27.8761061946903, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=23.2931726907631, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=26.6968325791855, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082128, Length=310, Percent_Identity=23.5483870967742, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789149, Length=348, Percent_Identity=21.8390804597701, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790551, Length=298, Percent_Identity=22.4832214765101, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=304, Percent_Identity=23.3552631578947, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788279, Length=245, Percent_Identity=27.7551020408163, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56283; Mature: 56283

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKASLKTQTISTFLLIIFLSMVCTITTIGVYFYIMYFGKDPMLRPNNYYQKQSDKIQQF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
IVSKGEDILEDKNRLELENLVPQKGIGYQITDLEGKIIYGNEKERIIKNKKQLIESINKT
HHHCCHHHHHCCCCHHHHHCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHCCCC
DIDNLDRASVFGSKVKRYIPIVDSDSNVKGAAIIKYNIDTSVKEDKNEKIVHVFQVFLPF
CCCCCHHHHHHHHHHHHHCCEECCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCC
SPFVYIIIFTIIFTRKLIKSIQHPINAIIDASNKIKEKDLNFEINYKSNNELGKLVSSFE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCEEEEECCCCHHHHHHHHHH
EMKNALKESLNKQWIMEEDRKEIIKAIAHDLKTPITVIQGHVEVLMEGGVKDPIRVEKYL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
NIIKANTERMGRLISDMNLTSEIENKNFDLVPVKVDIIEFLEKKQQDYKVLCKDKNIEFK
HHHHCCHHHHHHHHHHCCCHHHHCCCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCEEE
LFLEKNFNLNKEFSIDAERLEQILDNIISNAIRYTPDGKSIITKVKIHNNIIKFIVEDEG
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCHHHEEEEEECCCEEEEEEECCC
TGFSDKELCYIFEKFYRGDSSRSKEKGHSGLGMYIVRILVEKHNGWIVAENKEKGGARIE
CCCCCHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEE
FVIKEI
EEEECC
>Mature Secondary Structure
MKKASLKTQTISTFLLIIFLSMVCTITTIGVYFYIMYFGKDPMLRPNNYYQKQSDKIQQF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
IVSKGEDILEDKNRLELENLVPQKGIGYQITDLEGKIIYGNEKERIIKNKKQLIESINKT
HHHCCHHHHHCCCCHHHHHCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHCCCC
DIDNLDRASVFGSKVKRYIPIVDSDSNVKGAAIIKYNIDTSVKEDKNEKIVHVFQVFLPF
CCCCCHHHHHHHHHHHHHCCEECCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCC
SPFVYIIIFTIIFTRKLIKSIQHPINAIIDASNKIKEKDLNFEINYKSNNELGKLVSSFE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCEEEEECCCCHHHHHHHHHH
EMKNALKESLNKQWIMEEDRKEIIKAIAHDLKTPITVIQGHVEVLMEGGVKDPIRVEKYL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
NIIKANTERMGRLISDMNLTSEIENKNFDLVPVKVDIIEFLEKKQQDYKVLCKDKNIEFK
HHHHCCHHHHHHHHHHCCCHHHHCCCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCEEE
LFLEKNFNLNKEFSIDAERLEQILDNIISNAIRYTPDGKSIITKVKIHNNIIKFIVEDEG
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCHHHEEEEEECCCEEEEEEECCC
TGFSDKELCYIFEKFYRGDSSRSKEKGHSGLGMYIVRILVEKHNGWIVAENKEKGGARIE
CCCCCHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEE
FVIKEI
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]