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The map label for this gene is fabF [C]

Identifier: 170751402

GI number: 170751402

Start: 5337895

End: 5339034

Strand: Direct

Name: fabF [C]

Synonym: Mrad2831_5021

Alternate gene names: 170751402

Gene position: 5337895-5339034 (Clockwise)

Preceding gene: 170751401

Following gene: 170751403

Centisome position: 87.83

GC content: 76.05

Gene sequence:

>1140_bases
ATGAGCCGCCCCGTCGTCGTCACCGGCCTCGGCCTCGTCTCCTGCGCGGGTGAGGGCGTCGACGCCCACCTGGCCGCCCT
CGCCGGGGAGGCTGCCCCGCGCACCGACAGCGAGACCTTCGCGCCCTATCCGGTCCATCCGGCCCCGGCGATCGCGTGGG
ACGGCCAGATCCCCAAGCGCAGCGACCAGCGGCAGATGGAGGCGTGGCAGCGGCTCGGGGTCTACGCCGCCGGCCTCGCC
CTCGACGAGGCGGGCGTGAAGGACGACGCCGCCTTCAAGCAGGCGCTTCACCTCGTCGTGGCCGCGGGCGGCGGCGAGCG
CGACTACGCGGCGGACGGCGCGATCCTGACCGGTCTGCGCGACGCCGCAGATCCGGGCGCCTACCTGAACGAGCGCCTTC
AGAACGATCTCCGTCCGACGCTGTTCCTCGCCCAGCTCTCGAACCTGCTCGCCGGCAACATCGCCATCGTGCACGGGGTG
ACGGGCGCCTCGCGCACGTTCATGGGCGAGGAATCCGCCGGCGTCGACGCCCTGCGGATCGCCCAGGCGCGGGTGGCTTC
GGGCCAGATCGACGCGATCCTGGTCGGCGGCTCCTACAGCGCCGAGCGGCCGGACGTTCTGGTGATCCACGAGATGGGCG
GCTATCTCGCCCGCGACGCCTATCGCCCGGTCTTCGCGCGGGGCGACGCGGGTGGCGAGGCGGGCGGGTTCATCCTCGGG
AGCTGTGCGGCCTTCCTGATGCTCGAATCCGCCGCGCACGCTGCCGCCCGCGGCGCCCGCGCCCTGGCCCGGCTGGAGCC
GGTGGCGAGTGACCGGACCCGGCGCGTGCCGGGCAGCGTCGCCGGTAGCCTCGAGACCCTCTGGCGGCGGGCTGGCCTCT
CGGCTCCCGACCACGTCCTGTCCGGTGCCACCGGCGTCGCCCCGATCACCGCGGAGGAGCGCGCGGCGCTGGCGCAGCTC
GCGCCGCGCGCGCGCCTGCGTGCCCTCGGGGACGTGATCGGGCACGGGCTCGAGGTGGCGGCGCCCTTCGGGGCGGCGCT
CGCCGCCGCCCTCGTCGCCGACGGCCGCGCCCGCGAGGTCGCCGTGACCGCCGTCGGCCACCGGCGCGGCGAGGGTGTCC
TGCGCCTCGTCCCGGCCTGA

Upstream 100 bases:

>100_bases
CCGTTCCCGGACGGGCTCGACGCGCCGATGCGCGAGCGGGCGCGGACGATCGGCCTGTTTCCCGATTCGGCGCCGGCCGA
ACGCGAGCCCTGAGTCAGCC

Downstream 100 bases:

>100_bases
GCGAACCCGCCGCCCGGGTGCGCGCCGGCCGCGTCCGATCGTCCGGTCGGCAGCACAGATTTCGCGCGGCCGCGCCGCAT
CGAAATCCCTTATCCCGTTG

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]

Alternate protein names: Beta-Ketoacyl Synthase; 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase II; 3-Oxoacyl-[Acyl-Carrier-Protein] Synthase II Protein; 3-Oxoacyl-(Acyl-Acp) Synthase II Protein; 3-Oxoacyl-[Acyl-Carrier-Protein] Synthase II

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSRPVVVTGLGLVSCAGEGVDAHLAALAGEAAPRTDSETFAPYPVHPAPAIAWDGQIPKRSDQRQMEAWQRLGVYAAGLA
LDEAGVKDDAAFKQALHLVVAAGGGERDYAADGAILTGLRDAADPGAYLNERLQNDLRPTLFLAQLSNLLAGNIAIVHGV
TGASRTFMGEESAGVDALRIAQARVASGQIDAILVGGSYSAERPDVLVIHEMGGYLARDAYRPVFARGDAGGEAGGFILG
SCAAFLMLESAAHAAARGARALARLEPVASDRTRRVPGSVAGSLETLWRRAGLSAPDHVLSGATGVAPITAEERAALAQL
APRARLRALGDVIGHGLEVAAPFGAALAAALVADGRAREVAVTAVGHRRGEGVLRLVPA

Sequences:

>Translated_379_residues
MSRPVVVTGLGLVSCAGEGVDAHLAALAGEAAPRTDSETFAPYPVHPAPAIAWDGQIPKRSDQRQMEAWQRLGVYAAGLA
LDEAGVKDDAAFKQALHLVVAAGGGERDYAADGAILTGLRDAADPGAYLNERLQNDLRPTLFLAQLSNLLAGNIAIVHGV
TGASRTFMGEESAGVDALRIAQARVASGQIDAILVGGSYSAERPDVLVIHEMGGYLARDAYRPVFARGDAGGEAGGFILG
SCAAFLMLESAAHAAARGARALARLEPVASDRTRRVPGSVAGSLETLWRRAGLSAPDHVLSGATGVAPITAEERAALAQL
APRARLRALGDVIGHGLEVAAPFGAALAAALVADGRAREVAVTAVGHRRGEGVLRLVPA
>Mature_378_residues
SRPVVVTGLGLVSCAGEGVDAHLAALAGEAAPRTDSETFAPYPVHPAPAIAWDGQIPKRSDQRQMEAWQRLGVYAAGLAL
DEAGVKDDAAFKQALHLVVAAGGGERDYAADGAILTGLRDAADPGAYLNERLQNDLRPTLFLAQLSNLLAGNIAIVHGVT
GASRTFMGEESAGVDALRIAQARVASGQIDAILVGGSYSAERPDVLVIHEMGGYLARDAYRPVFARGDAGGEAGGFILGS
CAAFLMLESAAHAAARGARALARLEPVASDRTRRVPGSVAGSLETLWRRAGLSAPDHVLSGATGVAPITAEERAALAQLA
PRARLRALGDVIGHGLEVAAPFGAALAAALVADGRAREVAVTAVGHRRGEGVLRLVPA

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Has A Preference For Short Chain Acid Substrates And May Function To Supply The Octanoic Substrates For Lipoic Acid Biosynthe

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.41 [C]

Molecular weight: Translated: 38893; Mature: 38761

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPVVVTGLGLVSCAGEGVDAHLAALAGEAAPRTDSETFAPYPVHPAPAIAWDGQIPKR
CCCCEEEECCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
SDQRQMEAWQRLGVYAAGLALDEAGVKDDAAFKQALHLVVAAGGGERDYAADGAILTGLR
CHHHHHHHHHHHCHHHHCEEECCCCCCCHHHHHHHHHEEEECCCCCCCCCCCCHHHHCCH
DAADPGAYLNERLQNDLRPTLFLAQLSNLLAGNIAIVHGVTGASRTFMGEESAGVDALRI
HCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEECCCCCCEECCCCCCCCHHHHH
AQARVASGQIDAILVGGSYSAERPDVLVIHEMGGYLARDAYRPVFARGDAGGEAGGFILG
HHHHHCCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHHCCCEEECCCCCCCCCCHHHH
SCAAFLMLESAAHAAARGARALARLEPVASDRTRRVPGSVAGSLETLWRRAGLSAPDHVL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHH
SGATGVAPITAEERAALAQLAPRARLRALGDVIGHGLEVAAPFGAALAAALVADGRAREV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCEE
AVTAVGHRRGEGVLRLVPA
EEEEECCCCCCCEEEECCC
>Mature Secondary Structure 
SRPVVVTGLGLVSCAGEGVDAHLAALAGEAAPRTDSETFAPYPVHPAPAIAWDGQIPKR
CCCEEEECCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
SDQRQMEAWQRLGVYAAGLALDEAGVKDDAAFKQALHLVVAAGGGERDYAADGAILTGLR
CHHHHHHHHHHHCHHHHCEEECCCCCCCHHHHHHHHHEEEECCCCCCCCCCCCHHHHCCH
DAADPGAYLNERLQNDLRPTLFLAQLSNLLAGNIAIVHGVTGASRTFMGEESAGVDALRI
HCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEECCCCCCEECCCCCCCCHHHHH
AQARVASGQIDAILVGGSYSAERPDVLVIHEMGGYLARDAYRPVFARGDAGGEAGGFILG
HHHHHCCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHHCCCEEECCCCCCCCCCHHHH
SCAAFLMLESAAHAAARGARALARLEPVASDRTRRVPGSVAGSLETLWRRAGLSAPDHVL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHH
SGATGVAPITAEERAALAQLAPRARLRALGDVIGHGLEVAAPFGAALAAALVADGRAREV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCEE
AVTAVGHRRGEGVLRLVPA
EEEEECCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: None [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} [C]

Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]

Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]

General reaction: Acyl group transfer [C]

Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA