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The map label for this gene is fabZ [H]

Identifier: 170751401

GI number: 170751401

Start: 5337408

End: 5337887

Strand: Direct

Name: fabZ [H]

Synonym: Mrad2831_5020

Alternate gene names: 170751401

Gene position: 5337408-5337887 (Clockwise)

Preceding gene: 170751400

Following gene: 170751402

Centisome position: 87.82

GC content: 71.25

Gene sequence:

>480_bases
ATGCGCCTCGAATATTTCGAGATGATCGATTCCGTGCGGCTCCTCGACAGGGCCGCCGGCCGCATCGAGGCGCTCGCCCG
GGTTCCGATGGCGAGCCCGGTCTTCGAGGGGCATTTCCCCGGCCATCCCCTCGTGCCGGGGGTGCTCCTGACCGAGACGA
TGGCCCAGGCCTCCGGGTACCTCGTGCTCGCCCATCTCGACTTCGCCCGGATGCCGTTCCTCACCGGGGTCGACAAGGCG
CGCTTCCGGTCCTTCGTCGGGCCCGGCGCGGACCTCCTCGTCACGGCGACCCTGGAGCACGACGGCTCGGGCTACGCGGT
GACCAAGGCGGCGATCAGCCACGACGGCAAGGCGCTGTGCGACGCGGAGCTCCGCTTCCGCACCATGCCGTTCCCGGACG
GGCTCGACGCGCCGATGCGCGAGCGGGCGCGGACGATCGGCCTGTTTCCCGATTCGGCGCCGGCCGAACGCGAGCCCTGA

Upstream 100 bases:

>100_bases
GCCGAGGAGTACTTCGTCCTCAAGAACCTGTGCGCGCGCATCGACGGCCTCGTGGCCGAGAAGGCCGCCAAGGTCTGAAC
CAAGGCCGATCCGACCCGTC

Downstream 100 bases:

>100_bases
GTCAGCCATGAGCCGCCCCGTCGTCGTCACCGGCCTCGGCCTCGTCTCCTGCGCGGGTGAGGGCGTCGACGCCCACCTGG
CCGCCCTCGCCGGGGAGGCT

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MRLEYFEMIDSVRLLDRAAGRIEALARVPMASPVFEGHFPGHPLVPGVLLTETMAQASGYLVLAHLDFARMPFLTGVDKA
RFRSFVGPGADLLVTATLEHDGSGYAVTKAAISHDGKALCDAELRFRTMPFPDGLDAPMRERARTIGLFPDSAPAEREP

Sequences:

>Translated_159_residues
MRLEYFEMIDSVRLLDRAAGRIEALARVPMASPVFEGHFPGHPLVPGVLLTETMAQASGYLVLAHLDFARMPFLTGVDKA
RFRSFVGPGADLLVTATLEHDGSGYAVTKAAISHDGKALCDAELRFRTMPFPDGLDAPMRERARTIGLFPDSAPAEREP
>Mature_159_residues
MRLEYFEMIDSVRLLDRAAGRIEALARVPMASPVFEGHFPGHPLVPGVLLTETMAQASGYLVLAHLDFARMPFLTGVDKA
RFRSFVGPGADLLVTATLEHDGSGYAVTKAAISHDGKALCDAELRFRTMPFPDGLDAPMRERARTIGLFPDSAPAEREP

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=123, Percent_Identity=37.3983739837398, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 17339; Mature: 17339

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLEYFEMIDSVRLLDRAAGRIEALARVPMASPVFEGHFPGHPLVPGVLLTETMAQASGY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCE
LVLAHLDFARMPFLTGVDKARFRSFVGPGADLLVTATLEHDGSGYAVTKAAISHDGKALC
EEEEECCHHHCCHHCCCCHHHHHHHCCCCCCEEEEEEEECCCCCEEEEHHHHHCCCCEEE
DAELRFRTMPFPDGLDAPMRERARTIGLFPDSAPAEREP
CCCEEEEECCCCCCCCCHHHHHHHEECCCCCCCCCCCCC
>Mature Secondary Structure
MRLEYFEMIDSVRLLDRAAGRIEALARVPMASPVFEGHFPGHPLVPGVLLTETMAQASGY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCE
LVLAHLDFARMPFLTGVDKARFRSFVGPGADLLVTATLEHDGSGYAVTKAAISHDGKALC
EEEEECCHHHCCHHCCCCHHHHHHHCCCCCCEEEEEEEECCCCCEEEEHHHHHCCCCEEE
DAELRFRTMPFPDGLDAPMRERARTIGLFPDSAPAEREP
CCCEEEEECCCCCCCCCHHHHHHHEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA