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The map label for this gene is fadB1 [H]

Identifier: 170750226

GI number: 170750226

Start: 4072782

End: 4073564

Strand: Reverse

Name: fadB1 [H]

Synonym: Mrad2831_3828

Alternate gene names: 170750226

Gene position: 4073564-4072782 (Counterclockwise)

Preceding gene: 170750227

Following gene: 170750225

Centisome position: 67.02

GC content: 75.22

Gene sequence:

>783_bases
ATGGCCGAACCCGTCACGATCGACGACCTCGCGGGCGGCGTCCGCCTGATCACCCTGAACCGTCCGGAGAAGAAGAACGC
CCTCACGGGCGCCATGTACGACGCGATGCGCGCGGGCCTGGCGGAGGCCGACGCGTCGGACGCGGTCGGCGCCGTGGTCT
TCGCCGGGCAGCCCGGCATGTTCAGCGCCGGCAACGACCTCGCCGACTTCATGCGCCAGGCGTCCGGGGACAGGGCCGAG
GACGGCTTCAGCACCTCGCCGGCGCTGGCCTTCATCCGCCAGCTCGCCCGCACCCGCACCCCGATGGTGGCGGCGGTCGA
CGGGATCGCGGTCGGCATCGGCGCGACCCTCTGCCTGCACTGCGACCTCGTCTACGCGAGCCCGGCGGCGCGCCTGCGCA
TGCCCTTCGTCGAGCTCGGCCTCGTGCCGGAGGCGGCGTCGAGCTACCTGCTGCCCCTGCGGGTCGGCCGGCTCAGGGCC
ACCGAGCTGCTGCTCCTGTCGCGGCCGCTCGAGGCCGACGAGGCGCAGGCGCTGGGTCTCGTCAACGCGGTGCTGCCGGC
CGACATGCTGGTCGAGCAGGCGATCGCGCAGGCGGCGCGCCTCGCCGCCCTGCCGCGCGGGGCGCTGACGGCGTCCCGGG
CGCTGATCCGGGGCGACCAGGCGCAGGTCGAGGCGGCCCTGGAGGCCGAGGCCAAGGCCTTCGACGCCCAGCTGCGCTCG
CCCGAATCCCAGGAGCGGCTCGCCGCCTTCCTGTCGCGGTCGAAGCCCGCCGCCTCGGCGTGA

Upstream 100 bases:

>100_bases
AACCTCCTGGTGGCCGCTTCCGGCCTGGAGCAGGCGGTGGTCGAGGGCGGCGCCTTCACGGACGACGCCGCCCTGGCGCT
GGCGGTTTGAGGAGCGGACC

Downstream 100 bases:

>100_bases
GCCCGCCCGACCTCTCCGAGAAGATCTGCCTCGTCGCGGGCGCGTCGCGGGGTGTCGGCCGGGGACTCGCCCGGGCGCTG
GGCGAGGCGGGGGCCACGGT

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MAEPVTIDDLAGGVRLITLNRPEKKNALTGAMYDAMRAGLAEADASDAVGAVVFAGQPGMFSAGNDLADFMRQASGDRAE
DGFSTSPALAFIRQLARTRTPMVAAVDGIAVGIGATLCLHCDLVYASPAARLRMPFVELGLVPEAASSYLLPLRVGRLRA
TELLLLSRPLEADEAQALGLVNAVLPADMLVEQAIAQAARLAALPRGALTASRALIRGDQAQVEAALEAEAKAFDAQLRS
PESQERLAAFLSRSKPAASA

Sequences:

>Translated_260_residues
MAEPVTIDDLAGGVRLITLNRPEKKNALTGAMYDAMRAGLAEADASDAVGAVVFAGQPGMFSAGNDLADFMRQASGDRAE
DGFSTSPALAFIRQLARTRTPMVAAVDGIAVGIGATLCLHCDLVYASPAARLRMPFVELGLVPEAASSYLLPLRVGRLRA
TELLLLSRPLEADEAQALGLVNAVLPADMLVEQAIAQAARLAALPRGALTASRALIRGDQAQVEAALEAEAKAFDAQLRS
PESQERLAAFLSRSKPAASA
>Mature_259_residues
AEPVTIDDLAGGVRLITLNRPEKKNALTGAMYDAMRAGLAEADASDAVGAVVFAGQPGMFSAGNDLADFMRQASGDRAED
GFSTSPALAFIRQLARTRTPMVAAVDGIAVGIGATLCLHCDLVYASPAARLRMPFVELGLVPEAASSYLLPLRVGRLRAT
ELLLLSRPLEADEAQALGLVNAVLPADMLVEQAIAQAARLAALPRGALTASRALIRGDQAQVEAALEAEAKAFDAQLRSP
ESQERLAAFLSRSKPAASA

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI45643119, Length=252, Percent_Identity=33.7301587301587, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI260275230, Length=252, Percent_Identity=33.7301587301587, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI260274832, Length=251, Percent_Identity=33.8645418326693, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI194097323, Length=250, Percent_Identity=31.2, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI4757968, Length=242, Percent_Identity=28.099173553719, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI49355787, Length=242, Percent_Identity=28.099173553719, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI221136756, Length=244, Percent_Identity=25.8196721311475, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI221136753, Length=244, Percent_Identity=25.8196721311475, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI25453481, Length=242, Percent_Identity=26.8595041322314, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI51538573, Length=242, Percent_Identity=26.8595041322314, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI4757966, Length=223, Percent_Identity=28.2511210762332, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI51538581, Length=223, Percent_Identity=28.2511210762332, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI221307494, Length=244, Percent_Identity=25.8196721311475, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI31542718, Length=253, Percent_Identity=29.2490118577075, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI116235487, Length=207, Percent_Identity=27.536231884058, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI68989263, Length=196, Percent_Identity=33.1632653061224, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4502327, Length=250, Percent_Identity=27.6, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI70995211, Length=179, Percent_Identity=30.1675977653631, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI20127408, Length=187, Percent_Identity=30.4812834224599, Blast_Score=68, Evalue=6e-12,
Organism=Escherichia coli, GI1787659, Length=244, Percent_Identity=32.7868852459016, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1787660, Length=256, Percent_Identity=32.421875, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788597, Length=259, Percent_Identity=26.6409266409266, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788682, Length=205, Percent_Identity=29.2682926829268, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17535521, Length=249, Percent_Identity=32.1285140562249, Blast_Score=123, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17554946, Length=248, Percent_Identity=28.2258064516129, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25145438, Length=251, Percent_Identity=29.8804780876494, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17549921, Length=225, Percent_Identity=31.5555555555556, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17540714, Length=251, Percent_Identity=30.2788844621514, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540306, Length=250, Percent_Identity=28, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17560910, Length=252, Percent_Identity=25.3968253968254, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6320241, Length=158, Percent_Identity=33.5443037974684, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654903, Length=250, Percent_Identity=34.4, Blast_Score=141, Evalue=4e-34,
Organism=Drosophila melanogaster, GI20129971, Length=245, Percent_Identity=28.5714285714286, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24653477, Length=245, Percent_Identity=28.5714285714286, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24653139, Length=257, Percent_Identity=28.4046692607004, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21357171, Length=206, Percent_Identity=28.1553398058252, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24650670, Length=206, Percent_Identity=27.1844660194175, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27122; Mature: 26991

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPVTIDDLAGGVRLITLNRPEKKNALTGAMYDAMRAGLAEADASDAVGAVVFAGQPGM
CCCCCCHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCHHHCCCCCCCEEEEEECCCCC
FSAGNDLADFMRQASGDRAEDGFSTSPALAFIRQLARTRTPMVAAVDGIAVGIGATLCLH
CCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHH
CDLVYASPAARLRMPFVELGLVPEAASSYLLPLRVGRLRATELLLLSRPLEADEAQALGL
HHHHCCCCHHHHCCCHHHHCCCCHHHHCEEHHHHHCHHHHHHHHHHCCCCCCHHHHHHHH
VNAVLPADMLVEQAIAQAARLAALPRGALTASRALIRGDQAQVEAALEAEAKAFDAQLRS
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
PESQERLAAFLSRSKPAASA
CCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AEPVTIDDLAGGVRLITLNRPEKKNALTGAMYDAMRAGLAEADASDAVGAVVFAGQPGM
CCCCCHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCHHHCCCCCCCEEEEEECCCCC
FSAGNDLADFMRQASGDRAEDGFSTSPALAFIRQLARTRTPMVAAVDGIAVGIGATLCLH
CCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHH
CDLVYASPAARLRMPFVELGLVPEAASSYLLPLRVGRLRATELLLLSRPLEADEAQALGL
HHHHCCCCHHHHCCCHHHHCCCCHHHHCEEHHHHHCHHHHHHHHHHCCCCCCHHHHHHHH
VNAVLPADMLVEQAIAQAARLAALPRGALTASRALIRGDQAQVEAALEAEAKAFDAQLRS
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
PESQERLAAFLSRSKPAASA
CCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]