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The map label for this gene is fabG [H]

Identifier: 170750225

GI number: 170750225

Start: 4071943

End: 4072785

Strand: Reverse

Name: fabG [H]

Synonym: Mrad2831_3827

Alternate gene names: 170750225

Gene position: 4072785-4071943 (Counterclockwise)

Preceding gene: 170750226

Following gene: 170750224

Centisome position: 67.01

GC content: 77.34

Gene sequence:

>843_bases
GTGAGCCCGCCCGACCTCTCCGAGAAGATCTGCCTCGTCGCGGGCGCGTCGCGGGGTGTCGGCCGGGGACTCGCCCGGGC
GCTGGGCGAGGCGGGGGCCACGGTGATCGTCACGGCCCGCTCCAGCGAGACCGGCCCGCGCACCGAGATGCGCGCGGAGG
CGATCGAGGACACGGCCCGCGCGGTCGACGCGGCCGGCGGGCGCGGGCACCATTACCTGTGCGACCACCGCTCCGAGCGC
GCCACTGACGCGCTGATGCACTGGGCGCTCCGCCGGTTCGGGCGGATCGACGTCGCGGCCTGCAGCGTGTGGAGCGGCAA
CGAGGGCTACGACGGCGAGCGCTACCCGGACGGCGCCGGCTGGGGCACGCCGTTCTGGCGCCGCTCGGCAGAGCCGTATC
TCGGCCTCCTCGAGGCCGGGCCCCTGCCGGCCCTGCTGCTCGCCCGCGCGGTCGCCCCCGCCATGGTGGCGGCGCGGGCC
GGGCTGCTGGCGCTCGTCTCCTTCGGGACCGAAGATTACCTCGGCGACGTGTTCTACGATTCCGCCAAGGCCGCGACCAA
CCGGCTGACCCTGGCCTTCGCGCGGGAGCTCGCGCCCCACGGCGTCACCGCCCTCGGCCTCTCGCCGGGCTTCGTCGCCA
CCGAGCGGGCGCGCGACCTCGGCCACGCGCAGCACGCCACCGAGAGCCCGCTCTATGCCGGCCGGGCGCTGGCGGCGCTC
GCCGCCGACCCCGGCATCGCCGCGCGGGCGGGCGCCGTGCTGCATGCCGGCGACCTCGCGCGGGTCTACGGGTTCACCGA
CGCCGACGGGACGCGGCCGGAGCGGTTCCGCGTCGGGCCGTGA

Upstream 100 bases:

>100_bases
TGGAGGCCGAGGCCAAGGCCTTCGACGCCCAGCTGCGCTCGCCCGAATCCCAGGAGCGGCTCGCCGCCTTCCTGTCGCGG
TCGAAGCCCGCCGCCTCGGC

Downstream 100 bases:

>100_bases
CGGTTCCGGCTAGACCTGTCGCACGAATGGCGCAGCCCCGCGGCAAACGGGCCGGATCCGCCCCATGACCCGTCGGCGGG
GTTGATTCACCGGGTCCGGA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MSPPDLSEKICLVAGASRGVGRGLARALGEAGATVIVTARSSETGPRTEMRAEAIEDTARAVDAAGGRGHHYLCDHRSER
ATDALMHWALRRFGRIDVAACSVWSGNEGYDGERYPDGAGWGTPFWRRSAEPYLGLLEAGPLPALLLARAVAPAMVAARA
GLLALVSFGTEDYLGDVFYDSAKAATNRLTLAFARELAPHGVTALGLSPGFVATERARDLGHAQHATESPLYAGRALAAL
AADPGIAARAGAVLHAGDLARVYGFTDADGTRPERFRVGP

Sequences:

>Translated_280_residues
MSPPDLSEKICLVAGASRGVGRGLARALGEAGATVIVTARSSETGPRTEMRAEAIEDTARAVDAAGGRGHHYLCDHRSER
ATDALMHWALRRFGRIDVAACSVWSGNEGYDGERYPDGAGWGTPFWRRSAEPYLGLLEAGPLPALLLARAVAPAMVAARA
GLLALVSFGTEDYLGDVFYDSAKAATNRLTLAFARELAPHGVTALGLSPGFVATERARDLGHAQHATESPLYAGRALAAL
AADPGIAARAGAVLHAGDLARVYGFTDADGTRPERFRVGP
>Mature_279_residues
SPPDLSEKICLVAGASRGVGRGLARALGEAGATVIVTARSSETGPRTEMRAEAIEDTARAVDAAGGRGHHYLCDHRSERA
TDALMHWALRRFGRIDVAACSVWSGNEGYDGERYPDGAGWGTPFWRRSAEPYLGLLEAGPLPALLLARAVAPAMVAARAG
LLALVSFGTEDYLGDVFYDSAKAATNRLTLAFARELAPHGVTALGLSPGFVATERARDLGHAQHATESPLYAGRALAALA
ADPGIAARAGAVLHAGDLARVYGFTDADGTRPERFRVGP

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI209862901, Length=290, Percent_Identity=30.6896551724138, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI19923983, Length=290, Percent_Identity=30.6896551724138, Blast_Score=113, Evalue=2e-25,
Organism=Escherichia coli, GI1787335, Length=220, Percent_Identity=29.0909090909091, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71997099, Length=288, Percent_Identity=30.9027777777778, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17555612, Length=288, Percent_Identity=29.1666666666667, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI86565303, Length=290, Percent_Identity=27.9310344827586, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=219, Percent_Identity=26.027397260274, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=233, Percent_Identity=25.7510729613734, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=214, Percent_Identity=25.2336448598131, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=218, Percent_Identity=25.6880733944954, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI23397609, Length=217, Percent_Identity=27.1889400921659, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 29330; Mature: 29199

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPPDLSEKICLVAGASRGVGRGLARALGEAGATVIVTARSSETGPRTEMRAEAIEDTAR
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
AVDAAGGRGHHYLCDHRSERATDALMHWALRRFGRIDVAACSVWSGNEGYDGERYPDGAG
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCC
WGTPFWRRSAEPYLGLLEAGPLPALLLARAVAPAMVAARAGLLALVSFGTEDYLGDVFYD
CCCHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
SAKAATNRLTLAFARELAPHGVTALGLSPGFVATERARDLGHAQHATESPLYAGRALAAL
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AADPGIAARAGAVLHAGDLARVYGFTDADGTRPERFRVGP
HCCCCCHHHCCCEEECCCHHHHEECCCCCCCCCCCEECCC
>Mature Secondary Structure 
SPPDLSEKICLVAGASRGVGRGLARALGEAGATVIVTARSSETGPRTEMRAEAIEDTAR
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
AVDAAGGRGHHYLCDHRSERATDALMHWALRRFGRIDVAACSVWSGNEGYDGERYPDGAG
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCC
WGTPFWRRSAEPYLGLLEAGPLPALLLARAVAPAMVAARAGLLALVSFGTEDYLGDVFYD
CCCHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
SAKAATNRLTLAFARELAPHGVTALGLSPGFVATERARDLGHAQHATESPLYAGRALAAL
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AADPGIAARAGAVLHAGDLARVYGFTDADGTRPERFRVGP
HCCCCCHHHCCCEEECCCHHHHEECCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]