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The map label for this gene is frr [H]

Identifier: 170749846

GI number: 170749846

Start: 3662668

End: 3663231

Strand: Reverse

Name: frr [H]

Synonym: Mrad2831_3446

Alternate gene names: 170749846

Gene position: 3663231-3662668 (Counterclockwise)

Preceding gene: 170749847

Following gene: 170749845

Centisome position: 60.27

GC content: 66.67

Gene sequence:

>564_bases
ATGGCCACACCGGAATTCGATCTCAACGACATCAAGCGCCGCATGCAGGGCGCCGTCGCCTCGCTCTCGAAGGATCTCGG
CTCGCTGCGCACCGGGCGCGCCACGCCGTCGCTCCTCGACCCGATCCAGGTCGACGCCTACGGCTCGATGATGCCGATGG
CCCAGGTCGCCACCGTCAGCGTGCCGGAGCCCCGGCTCCTGTCGATCTCGGTCTGGGACCGCAGCATGGTCACGGCCGTC
GAGAAAGCGATCCGCGAATCCGACCTCGGCCTCAACCCGCAGACCGAGGGGCAGACCATCCGGCTCCGCATCCCCGAGAT
GAACGAGCAGCGCCGCAAGGAGATGGTCAAGGTCGCCCACAAGTACACCGAGGAGGCCCGCGTCGCCGTGCGCCACGTGC
GCCGGGACGGCCTCGACCACCTCAAGAAGCTCCTGAAGGACAGCGCCATCTCGGAGGATGACGAGAAGCGTCAGGCCACC
GACGTTCAGAAGGCGACCGACCAGTACATCGCCGAGATCGACGGCGTGCTGGCCTCCAAGGAGAAGGAGATCATGCAGGT
CTGA

Upstream 100 bases:

>100_bases
GGGGTCGCGACCGTTTGCGGCCCTGAAAAAATTCGTCCATTGAGGCCGCGACTGCCCGCGCCGGGCTCAAGACCACGTCA
GACGTCTCGGGACGACCCTC

Downstream 100 bases:

>100_bases
GGCGCGGGACGGGACGCGCGTGACCTCCGCCGCCGCACCGGCCGCGCGTCCCTCGGGGCGGCGCGAGCTGTGGCTGCGCG
TCGCCTCGGGCCTCGTGCTC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MATPEFDLNDIKRRMQGAVASLSKDLGSLRTGRATPSLLDPIQVDAYGSMMPMAQVATVSVPEPRLLSISVWDRSMVTAV
EKAIRESDLGLNPQTEGQTIRLRIPEMNEQRRKEMVKVAHKYTEEARVAVRHVRRDGLDHLKKLLKDSAISEDDEKRQAT
DVQKATDQYIAEIDGVLASKEKEIMQV

Sequences:

>Translated_187_residues
MATPEFDLNDIKRRMQGAVASLSKDLGSLRTGRATPSLLDPIQVDAYGSMMPMAQVATVSVPEPRLLSISVWDRSMVTAV
EKAIRESDLGLNPQTEGQTIRLRIPEMNEQRRKEMVKVAHKYTEEARVAVRHVRRDGLDHLKKLLKDSAISEDDEKRQAT
DVQKATDQYIAEIDGVLASKEKEIMQV
>Mature_186_residues
ATPEFDLNDIKRRMQGAVASLSKDLGSLRTGRATPSLLDPIQVDAYGSMMPMAQVATVSVPEPRLLSISVWDRSMVTAVE
KAIRESDLGLNPQTEGQTIRLRIPEMNEQRRKEMVKVAHKYTEEARVAVRHVRRDGLDHLKKLLKDSAISEDDEKRQATD
VQKATDQYIAEIDGVLASKEKEIMQV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=181, Percent_Identity=30.939226519337, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI291042689, Length=148, Percent_Identity=34.4594594594595, Blast_Score=80, Evalue=8e-16,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=50, Blast_Score=176, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24661488, Length=181, Percent_Identity=26.5193370165746, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20998; Mature: 20867

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPEFDLNDIKRRMQGAVASLSKDLGSLRTGRATPSLLDPIQVDAYGSMMPMAQVATVS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHCCCCCCCHHHHHHCCC
VPEPRLLSISVWDRSMVTAVEKAIRESDLGLNPQTEGQTIRLRIPEMNEQRRKEMVKVAH
CCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
KYTEEARVAVRHVRRDGLDHLKKLLKDSAISEDDEKRQATDVQKATDQYIAEIDGVLASK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKEIMQV
HHHHHCC
>Mature Secondary Structure 
ATPEFDLNDIKRRMQGAVASLSKDLGSLRTGRATPSLLDPIQVDAYGSMMPMAQVATVS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHCCCCCCCHHHHHHCCC
VPEPRLLSISVWDRSMVTAVEKAIRESDLGLNPQTEGQTIRLRIPEMNEQRRKEMVKVAH
CCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
KYTEEARVAVRHVRRDGLDHLKKLLKDSAISEDDEKRQATDVQKATDQYIAEIDGVLASK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKEIMQV
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA