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The map label for this gene is pyrH [H]

Identifier: 170749847

GI number: 170749847

Start: 3663346

End: 3664086

Strand: Reverse

Name: pyrH [H]

Synonym: Mrad2831_3447

Alternate gene names: 170749847

Gene position: 3664086-3663346 (Counterclockwise)

Preceding gene: 170749848

Following gene: 170749846

Centisome position: 60.29

GC content: 71.66

Gene sequence:

>741_bases
ATGGAGCCGGGGGCCCAGATGCCGGAGACGACGCCGTTTCGCCGTATCCTCGTGAAGCTGTCGGGCGAGGCGCTCGCCGC
TCCGGACGGCTACTGGTTGCATCCGCCGACCCTGGCGGCGCTCGCCGAGGACATCGCCCGCACGATCGAGGCGGGTGCCG
AGATCGCCATCGTGGTGGGCGGCGGCAACATGATCCGCGGGGCGCGGATCTCCGCGGCCGGCTGGATCGACCGGGCGACC
GGGGATTCCCTCGGAATGATGGCCACGGTGATGAACTCGCTGGCGATCGAGACGGCGCTCAACGCCGCGGGCGTCCAGGC
GCGGACCATGTCGGCGGTGTCGATGCCGACCATCTGCGAGACCTACGCCCGCCAGCCGGCGCTGCACCATCTGGACAAGG
GCCAGGTGGTCGTCCTCGCCGGCGGCACCGGCAACCCGTTCTTCACCACCGACACCGCCGCGGTGCTGCGCGCCGCCGAG
CTGCGCTGCGACGCGGTTCTCAAGGCGACGCAGGTGGACGGCGTCTACTCGGCGGATCCGAAGAAGGATCCGAGCGCCAC
GCGCTACGACCGCATCACCCACGACGAGGCGATCGCCCGCGACCTCAAGGTGATGGACACCGCCGCCTTCGCGCTGGCCC
GGGAGAGCCGCCTGTCGATCGTGGTCGGCTCGCTCCACCCGCCGAGCTCGATCGCCGCGATCCTGTCGGGCGACGCGCCC
TCGACCCTCGTGGCGCCCTGA

Upstream 100 bases:

>100_bases
CGGTAGCATTTCGGCCCACGATCCCCGCCGTATCGGTGCCGGGCCTCTCGACGGCGCTCGGGCGGTTGACGTAGAAGCCT
CCCCGCTTGCGCGATGCGGG

Downstream 100 bases:

>100_bases
CACGCGGCACGATCGGGGTCGCGACCGTTTGCGGCCCTGAAAAAATTCGTCCATTGAGGCCGCGACTGCCCGCGCCGGGC
TCAAGACCACGTCAGACGTC

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MEPGAQMPETTPFRRILVKLSGEALAAPDGYWLHPPTLAALAEDIARTIEAGAEIAIVVGGGNMIRGARISAAGWIDRAT
GDSLGMMATVMNSLAIETALNAAGVQARTMSAVSMPTICETYARQPALHHLDKGQVVVLAGGTGNPFFTTDTAAVLRAAE
LRCDAVLKATQVDGVYSADPKKDPSATRYDRITHDEAIARDLKVMDTAAFALARESRLSIVVGSLHPPSSIAAILSGDAP
STLVAP

Sequences:

>Translated_246_residues
MEPGAQMPETTPFRRILVKLSGEALAAPDGYWLHPPTLAALAEDIARTIEAGAEIAIVVGGGNMIRGARISAAGWIDRAT
GDSLGMMATVMNSLAIETALNAAGVQARTMSAVSMPTICETYARQPALHHLDKGQVVVLAGGTGNPFFTTDTAAVLRAAE
LRCDAVLKATQVDGVYSADPKKDPSATRYDRITHDEAIARDLKVMDTAAFALARESRLSIVVGSLHPPSSIAAILSGDAP
STLVAP
>Mature_246_residues
MEPGAQMPETTPFRRILVKLSGEALAAPDGYWLHPPTLAALAEDIARTIEAGAEIAIVVGGGNMIRGARISAAGWIDRAT
GDSLGMMATVMNSLAIETALNAAGVQARTMSAVSMPTICETYARQPALHHLDKGQVVVLAGGTGNPFFTTDTAAVLRAAE
LRCDAVLKATQVDGVYSADPKKDPSATRYDRITHDEAIARDLKVMDTAAFALARESRLSIVVGSLHPPSSIAAILSGDAP
STLVAP

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=232, Percent_Identity=46.551724137931, Blast_Score=230, Evalue=8e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25644; Mature: 25644

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPGAQMPETTPFRRILVKLSGEALAAPDGYWLHPPTLAALAEDIARTIEAGAEIAIVVG
CCCCCCCCCCCHHHHHHHHCCCCEEECCCCCEECCHHHHHHHHHHHHHHHCCCEEEEEEC
GGNMIRGARISAAGWIDRATGDSLGMMATVMNSLAIETALNAAGVQARTMSAVSMPTICE
CCCEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
TYARQPALHHLDKGQVVVLAGGTGNPFFTTDTAAVLRAAELRCDAVLKATQVDGVYSADP
HHHCCHHHHHCCCCCEEEEECCCCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCEECCCC
KKDPSATRYDRITHDEAIARDLKVMDTAAFALARESRLSIVVGSLHPPSSIAAILSGDAP
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHEEECCCCC
STLVAP
CCCCCC
>Mature Secondary Structure
MEPGAQMPETTPFRRILVKLSGEALAAPDGYWLHPPTLAALAEDIARTIEAGAEIAIVVG
CCCCCCCCCCCHHHHHHHHCCCCEEECCCCCEECCHHHHHHHHHHHHHHHCCCEEEEEEC
GGNMIRGARISAAGWIDRATGDSLGMMATVMNSLAIETALNAAGVQARTMSAVSMPTICE
CCCEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
TYARQPALHHLDKGQVVVLAGGTGNPFFTTDTAAVLRAAELRCDAVLKATQVDGVYSADP
HHHCCHHHHHCCCCCEEEEECCCCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCEECCCC
KKDPSATRYDRITHDEAIARDLKVMDTAAFALARESRLSIVVGSLHPPSSIAAILSGDAP
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHEEECCCCC
STLVAP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA