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The map label for this gene is foxA [H]

Identifier: 170749807

GI number: 170749807

Start: 3615854

End: 3618022

Strand: Direct

Name: foxA [H]

Synonym: Mrad2831_3406

Alternate gene names: 170749807

Gene position: 3615854-3618022 (Clockwise)

Preceding gene: 170749806

Following gene: 170749811

Centisome position: 59.49

GC content: 69.06

Gene sequence:

>2169_bases
GTGGTACGGCGTAACTGTGCAAATCCTTGCACACAGGCTTCGCGCGGCGTTTCTGCGCGCGCAGTCAAGATCTCCCTGAT
CCTCGCACCGGTATTCCTTCCGTCCTCAGGCTCGGCACAATCTGCCGTTGACAGCGCCCAGGAGATCGAGCTGGAGGAGC
TCTCGGTGGCGGGGATCGGCGACGGGAATACCCGCGTCGACGGCTACCGGGTCGCGCGCGCGGTGAGCGCCACGCGGACC
GACACGCCCGTGCGCGAGGTGCCCCAGACCATCGTGGCGGTACCGCAGGAGGTGCTGGAGGACGCCGCGGCCACGCGGAT
CGACACGGCCCTCGACCTCGCGGGTGTCGGCCGCGGCAACAATTTCGGTGGCCTCGGTCTGACCGAGTTCACGATCCGCG
GCGTGGCCACCGGCGAGTATTACCGCAACGGATTCCCGATCAATCGCGGTTACCCGAACAGCCCCGACATCGTCTCCATC
GAGCGCATCGAGGTGCTGAAAGGCCCCTCGGCCTTCCTGTACGGCCGCGGCGATCCCGGCGGCACCTTCAACATCGTGAC
CAAGCAGCCCCTCGCGGCGCGCTCCCTCACGATCGGCACGCAGTACGGCAGCTTCGGCGCCAAGCGGAGCACCTTCGACG
CCACGGGCGCCCTCGACGAGAGCGGGCAGGTGCTGGCGCGCGTCACCGGCGCCGTCGAGGACAACGGCAGCTTCCGGGAC
TTCGTCACCAGCGACCGCTACGCCCTCGCCCCGGTCATCGCCTGGAAGCCGAATGCGGACACGACCATCACCCTGGAGGG
TGACTTCATCAGCACGGCGCAGACCTTCGACCGCGGCATCGTGCCGTTGGGAGGCAACGTGCGCGCCCTGCCGCGCAGCC
GCTTCATCGGCGAGCCGGGCCTGCCGCCGGCCCATGTCGACAACGCCCTCGGCCAGCTGCGCGTCGAGCACCGGTTCGAC
CAGGACTGGGTGCTGAACGCCGGCGCGCAGGTGCTCGGCGGGAACCTGTCGGGTTACGGGGTCGGCGCCATCGGCCTGCT
GCCGGATGGCCGGACCCAGCGGCGAACCCTGGAATGGCGGGACCTGACGTGGTCCGATCTCGACCTGCAGGCGAATCTCG
CGGGCAAATTCGAGACCGGCCCGTTCCGCCACACGCTCCTGCTCGGGCTGGAATACGACAGCTACCGCTACCGCGAGGTG
TTCAACCGCTCGAACGTCGCGACGAACCCGTTCCTCCTCGACCTGCTGGCACCGCGCTACGGCCAGCCGTTGCCGCCGAT
CACCGCGCGGGTCACGAACTTCCTGCAGAAGACCGAGAGCTACGCCGGCTACGTGCAGGACCAGATCGACCTGACGCCCC
GCCTCCACGCGCTCCTGGGTGTGCGGGTCGAGGATCTCGGGCTGGTCTCGACGAACAACCTCACGAAGGGCACCACCAGC
CTGCAGGGCCTGGTGGCGACGCCGCGCTTCGGCCTGCTCTACGACCTGACCGACACGGTCTCGGTCTACGGCAATTACGC
CCGCTCCTTCCGGCCCAATATCGGCACGGATCGCAGCGGCCGGCCCTTCGCGTTCGAGGAGGGTGAGGGCTACGAGGCCG
GCGCGAAGGTCAGCCTCCTCGACGGCCGCCTCGACGCCACCGCCGCCCTGTTCGAGATCCGGCGGTCCAACGTCCTCAGC
ACCGACCCGGTCGATCCGAACTTCAGCGTCGCCACCGGCGCAATCCGCAGCCGCGGCTTCGATCTGACCGCGGCGGGCTA
CCTCGCACCGGGCTGGCGCGTGATCGGGACCTACACGCGCGTCGACGCGGCCGTCGCCCGCGACAACACCCTTCCGGTCG
GCACGCGCATCGCCAACGTGCCCGCCAACAGCCTCGCGTTCCAGACGGTCTACGAGTTCCAGAGCGGCGAGCTGAAGGGT
CTGGGGCTCGGCGGCGGCCTCGACTTCGTCGGTCGTCGCGCCGCGGGGACGGCGCTCGCGACCTTCAACCTGCCGCAATA
CACGCTGGTCAACCTGATCTCGTACTACCAGATCGCGCCGGGCGTGCGGATCTACCTGAACGTCGACAACGTGTTCGACG
CGACGTTCTACGACCGGGCATTCCAGAACCGCTACGCGACGCCGGGGCAGCCGCGCACGATCATCGGCGGCGTCGCGGCC
CGGTTCTGA

Upstream 100 bases:

>100_bases
TTATTCGAAATCCAGCCTTCGGGATGACCTCGAGAGCAAGCTTGACCGTGAGTGTTTCTCTACCGTATCTGGCGCCACTC
GAAACAGAATGGTCGACATC

Downstream 100 bases:

>100_bases
GCCCCCGGCCTACGCCGCGTCCGCCCTCATCCAGCCGAGCCCCGCCTCGGTGCCGGCCGCGGGATGGTACTCGCAGCCGA
CGAAGCCGGAATAGCCGACC

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 722; Mature: 722

Protein sequence:

>722_residues
MVRRNCANPCTQASRGVSARAVKISLILAPVFLPSSGSAQSAVDSAQEIELEELSVAGIGDGNTRVDGYRVARAVSATRT
DTPVREVPQTIVAVPQEVLEDAAATRIDTALDLAGVGRGNNFGGLGLTEFTIRGVATGEYYRNGFPINRGYPNSPDIVSI
ERIEVLKGPSAFLYGRGDPGGTFNIVTKQPLAARSLTIGTQYGSFGAKRSTFDATGALDESGQVLARVTGAVEDNGSFRD
FVTSDRYALAPVIAWKPNADTTITLEGDFISTAQTFDRGIVPLGGNVRALPRSRFIGEPGLPPAHVDNALGQLRVEHRFD
QDWVLNAGAQVLGGNLSGYGVGAIGLLPDGRTQRRTLEWRDLTWSDLDLQANLAGKFETGPFRHTLLLGLEYDSYRYREV
FNRSNVATNPFLLDLLAPRYGQPLPPITARVTNFLQKTESYAGYVQDQIDLTPRLHALLGVRVEDLGLVSTNNLTKGTTS
LQGLVATPRFGLLYDLTDTVSVYGNYARSFRPNIGTDRSGRPFAFEEGEGYEAGAKVSLLDGRLDATAALFEIRRSNVLS
TDPVDPNFSVATGAIRSRGFDLTAAGYLAPGWRVIGTYTRVDAAVARDNTLPVGTRIANVPANSLAFQTVYEFQSGELKG
LGLGGGLDFVGRRAAGTALATFNLPQYTLVNLISYYQIAPGVRIYLNVDNVFDATFYDRAFQNRYATPGQPRTIIGGVAA
RF

Sequences:

>Translated_722_residues
MVRRNCANPCTQASRGVSARAVKISLILAPVFLPSSGSAQSAVDSAQEIELEELSVAGIGDGNTRVDGYRVARAVSATRT
DTPVREVPQTIVAVPQEVLEDAAATRIDTALDLAGVGRGNNFGGLGLTEFTIRGVATGEYYRNGFPINRGYPNSPDIVSI
ERIEVLKGPSAFLYGRGDPGGTFNIVTKQPLAARSLTIGTQYGSFGAKRSTFDATGALDESGQVLARVTGAVEDNGSFRD
FVTSDRYALAPVIAWKPNADTTITLEGDFISTAQTFDRGIVPLGGNVRALPRSRFIGEPGLPPAHVDNALGQLRVEHRFD
QDWVLNAGAQVLGGNLSGYGVGAIGLLPDGRTQRRTLEWRDLTWSDLDLQANLAGKFETGPFRHTLLLGLEYDSYRYREV
FNRSNVATNPFLLDLLAPRYGQPLPPITARVTNFLQKTESYAGYVQDQIDLTPRLHALLGVRVEDLGLVSTNNLTKGTTS
LQGLVATPRFGLLYDLTDTVSVYGNYARSFRPNIGTDRSGRPFAFEEGEGYEAGAKVSLLDGRLDATAALFEIRRSNVLS
TDPVDPNFSVATGAIRSRGFDLTAAGYLAPGWRVIGTYTRVDAAVARDNTLPVGTRIANVPANSLAFQTVYEFQSGELKG
LGLGGGLDFVGRRAAGTALATFNLPQYTLVNLISYYQIAPGVRIYLNVDNVFDATFYDRAFQNRYATPGQPRTIIGGVAA
RF
>Mature_722_residues
MVRRNCANPCTQASRGVSARAVKISLILAPVFLPSSGSAQSAVDSAQEIELEELSVAGIGDGNTRVDGYRVARAVSATRT
DTPVREVPQTIVAVPQEVLEDAAATRIDTALDLAGVGRGNNFGGLGLTEFTIRGVATGEYYRNGFPINRGYPNSPDIVSI
ERIEVLKGPSAFLYGRGDPGGTFNIVTKQPLAARSLTIGTQYGSFGAKRSTFDATGALDESGQVLARVTGAVEDNGSFRD
FVTSDRYALAPVIAWKPNADTTITLEGDFISTAQTFDRGIVPLGGNVRALPRSRFIGEPGLPPAHVDNALGQLRVEHRFD
QDWVLNAGAQVLGGNLSGYGVGAIGLLPDGRTQRRTLEWRDLTWSDLDLQANLAGKFETGPFRHTLLLGLEYDSYRYREV
FNRSNVATNPFLLDLLAPRYGQPLPPITARVTNFLQKTESYAGYVQDQIDLTPRLHALLGVRVEDLGLVSTNNLTKGTTS
LQGLVATPRFGLLYDLTDTVSVYGNYARSFRPNIGTDRSGRPFAFEEGEGYEAGAKVSLLDGRLDATAALFEIRRSNVLS
TDPVDPNFSVATGAIRSRGFDLTAAGYLAPGWRVIGTYTRVDAAVARDNTLPVGTRIANVPANSLAFQTVYEFQSGELKG
LGLGGGLDFVGRRAAGTALATFNLPQYTLVNLISYYQIAPGVRIYLNVDNVFDATFYDRAFQNRYATPGQPRTIIGGVAA
RF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=695, Percent_Identity=26.4748201438849, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI1787024, Length=711, Percent_Identity=25.1758087201125, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI1787344, Length=751, Percent_Identity=24.1011984021305, Blast_Score=135, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 77750; Mature: 77750

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.1 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.1 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRRNCANPCTQASRGVSARAVKISLILAPVFLPSSGSAQSAVDSAQEIELEELSVAGIG
CCCCCCCCHHHHHHCCCCEEEEEEEEEEEEEEECCCCCHHHHHHHHHHCCHHHEEEEECC
DGNTRVDGYRVARAVSATRTDTPVREVPQTIVAVPQEVLEDAAATRIDTALDLAGVGRGN
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC
NFGGLGLTEFTIRGVATGEYYRNGFPINRGYPNSPDIVSIERIEVLKGPSAFLYGRGDPG
CCCCCCCEEEEEEEEEECCHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEECCCCC
GTFNIVTKQPLAARSLTIGTQYGSFGAKRSTFDATGALDESGQVLARVTGAVEDNGSFRD
CEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHH
FVTSDRYALAPVIAWKPNADTTITLEGDFISTAQTFDRGIVPLGGNVRALPRSRFIGEPG
HHCCCCEEEEEEEEECCCCCEEEEEECCEECHHHHHHCCCEECCCCEEECCHHHCCCCCC
LPPAHVDNALGQLRVEHRFDQDWVLNAGAQVLGGNLSGYGVGAIGLLPDGRTQRRTLEWR
CCHHHHHHHHHHEEHHHCCCCCCEECCCCCEECCCCCCCCEEEEEECCCCCCCCCEEEEC
DLTWSDLDLQANLAGKFETGPFRHTLLLGLEYDSYRYREVFNRSNVATNPFLLDLLAPRY
CCCCCCCEEEEECCCCCCCCCCEEEEEEEEECCCHHHHHHHCCCCCCCCCCHHHHHCCCC
GQPLPPITARVTNFLQKTESYAGYVQDQIDLTPRLHALLGVRVEDLGLVSTNNLTKGTTS
CCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHCCEEHHEEEEECCCCCCCCCC
LQGLVATPRFGLLYDLTDTVSVYGNYARSFRPNIGTDRSGRPFAFEEGEGYEAGAKVSLL
CCEEEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCEEEEE
DGRLDATAALFEIRRSNVLSTDPVDPNFSVATGAIRSRGFDLTAAGYLAPGWRVIGTYTR
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHCCCCEEECCCCCCCCEEEEEHHH
VDAAVARDNTLPVGTRIANVPANSLAFQTVYEFQSGELKGLGLGGGLDFVGRRAAGTALA
HHHHHHCCCCCCCCCEEECCCCCHHHHHHHEECCCCCEEEEECCCCHHHHCCCCCCCEEE
TFNLPQYTLVNLISYYQIAPGVRIYLNVDNVFDATFYDRAFQNRYATPGQPRTIIGGVAA
EECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCEEECHHHH
RF
CC
>Mature Secondary Structure
MVRRNCANPCTQASRGVSARAVKISLILAPVFLPSSGSAQSAVDSAQEIELEELSVAGIG
CCCCCCCCHHHHHHCCCCEEEEEEEEEEEEEEECCCCCHHHHHHHHHHCCHHHEEEEECC
DGNTRVDGYRVARAVSATRTDTPVREVPQTIVAVPQEVLEDAAATRIDTALDLAGVGRGN
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC
NFGGLGLTEFTIRGVATGEYYRNGFPINRGYPNSPDIVSIERIEVLKGPSAFLYGRGDPG
CCCCCCCEEEEEEEEEECCHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEECCCCC
GTFNIVTKQPLAARSLTIGTQYGSFGAKRSTFDATGALDESGQVLARVTGAVEDNGSFRD
CEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHH
FVTSDRYALAPVIAWKPNADTTITLEGDFISTAQTFDRGIVPLGGNVRALPRSRFIGEPG
HHCCCCEEEEEEEEECCCCCEEEEEECCEECHHHHHHCCCEECCCCEEECCHHHCCCCCC
LPPAHVDNALGQLRVEHRFDQDWVLNAGAQVLGGNLSGYGVGAIGLLPDGRTQRRTLEWR
CCHHHHHHHHHHEEHHHCCCCCCEECCCCCEECCCCCCCCEEEEEECCCCCCCCCEEEEC
DLTWSDLDLQANLAGKFETGPFRHTLLLGLEYDSYRYREVFNRSNVATNPFLLDLLAPRY
CCCCCCCEEEEECCCCCCCCCCEEEEEEEEECCCHHHHHHHCCCCCCCCCCHHHHHCCCC
GQPLPPITARVTNFLQKTESYAGYVQDQIDLTPRLHALLGVRVEDLGLVSTNNLTKGTTS
CCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHCCEEHHEEEEECCCCCCCCCC
LQGLVATPRFGLLYDLTDTVSVYGNYARSFRPNIGTDRSGRPFAFEEGEGYEAGAKVSLL
CCEEEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCEEEEE
DGRLDATAALFEIRRSNVLSTDPVDPNFSVATGAIRSRGFDLTAAGYLAPGWRVIGTYTR
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHCCCCEEECCCCCCCCEEEEEHHH
VDAAVARDNTLPVGTRIANVPANSLAFQTVYEFQSGELKGLGLGGGLDFVGRRAAGTALA
HHHHHHCCCCCCCCCEEECCCCCHHHHHHHEECCCCCEEEEECCCCHHHHCCCCCCCEEE
TFNLPQYTLVNLISYYQIAPGVRIYLNVDNVFDATFYDRAFQNRYATPGQPRTIIGGVAA
EECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCEEECHHHH
RF
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]