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The map label for this gene is gsiC [H]

Identifier: 170749645

GI number: 170749645

Start: 3434770

End: 3435690

Strand: Reverse

Name: gsiC [H]

Synonym: Mrad2831_3242

Alternate gene names: 170749645

Gene position: 3435690-3434770 (Counterclockwise)

Preceding gene: 170749646

Following gene: 170749644

Centisome position: 56.53

GC content: 68.51

Gene sequence:

>921_bases
ATGCTGACCTTCCTGCTCAAGCGGCTCCTCGGGCTGCTGCCGACGCTGCTGATCGTCTCGGTGCTGGTCTTCCTGTTCGT
CCACCTGCTGCCCGGCGATCCGGCGCGGCTGGCGGCCGGGCAGGATGCCGACGCCCAGACGGTGGCGCTGGTGCGCACCG
AACTCGGCCTCGACCGGCCGCTGCCGCAACAGTTCGTGCGCTACTTCGTCAACCTCGCCCGCGGGGATCTCGGCACCTCG
ATCCGCACCCGCCGTCCGGTCTCGACCGAGATCGGCGAGCGCTTCCTGCCGACCCTTCTGCTCACGCTCACCAGCATGGC
CTGGGCGGTCGCCTTCGGGCTGATCATCGGCATCGTCTCGGCGGTCTACCGCAACGAGTGGCCCGACCGGGTCGGGATGA
CGCTCGCCATTTCGGGCATCTCGTTCCCCGCCTTCGCGCTCGGCATCCTGCTGATGCAGATCTTCTCGGTCGAGCTCGGC
TGGCTGCCGACCGTCGGCGCCGACACGTGGCGGCACTACGTGCTGCCGTCGCTGACGCTGGGCGCGGCCGTGGCCGCCGT
GATGGCCCGCTTCACCCGCGCGGCCTTCGTGGAGGTCATCGGCGAGGATTTCGTCCGCACCGCGCGCGCCAAGGGGCTCA
AGGAGCGCGTCGTCATCGCCAAGCACTGCCTGCGCAACGCCCTGATCCCGGTCGTGACCATGATGGGCCTGCAGTTCGGC
TTCCTGCTCGGCGGCTCGATCGTCGTGGAGGCGGTGTTCAACTGGCCCGGCATGGGCCGCCTGCTCGTCGATGCCGTGAA
CCAGCGCGACTACCCGGTGATCCAGGCCCTGGTCCTGCTGTTCTCCCTGGAGTTCATCCTGATCAACCTGGTCGTGGACG
TGCTCTACGGCCTCATCAACCCGACCATCCGCTACAGGTGA

Upstream 100 bases:

>100_bases
GATCGCGGCCCCTGCGCCGGGCGGCCCGATCGATGGCCGGCCCGGCGCGGCGCTCCCGCGCGATCGCCTCACGGAAACCC
CGGATCCCGGGCGCGAGCCT

Downstream 100 bases:

>100_bases
GCCGGCCGTGACCGACATCCTCGTCCCCGCCGCCCCCACCGTCGCGCCCGTCCCCACCGGCATCCGGACGCCGTGGTCGG
AATTCTGGCGCAAGTTCCGC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MLTFLLKRLLGLLPTLLIVSVLVFLFVHLLPGDPARLAAGQDADAQTVALVRTELGLDRPLPQQFVRYFVNLARGDLGTS
IRTRRPVSTEIGERFLPTLLLTLTSMAWAVAFGLIIGIVSAVYRNEWPDRVGMTLAISGISFPAFALGILLMQIFSVELG
WLPTVGADTWRHYVLPSLTLGAAVAAVMARFTRAAFVEVIGEDFVRTARAKGLKERVVIAKHCLRNALIPVVTMMGLQFG
FLLGGSIVVEAVFNWPGMGRLLVDAVNQRDYPVIQALVLLFSLEFILINLVVDVLYGLINPTIRYR

Sequences:

>Translated_306_residues
MLTFLLKRLLGLLPTLLIVSVLVFLFVHLLPGDPARLAAGQDADAQTVALVRTELGLDRPLPQQFVRYFVNLARGDLGTS
IRTRRPVSTEIGERFLPTLLLTLTSMAWAVAFGLIIGIVSAVYRNEWPDRVGMTLAISGISFPAFALGILLMQIFSVELG
WLPTVGADTWRHYVLPSLTLGAAVAAVMARFTRAAFVEVIGEDFVRTARAKGLKERVVIAKHCLRNALIPVVTMMGLQFG
FLLGGSIVVEAVFNWPGMGRLLVDAVNQRDYPVIQALVLLFSLEFILINLVVDVLYGLINPTIRYR
>Mature_306_residues
MLTFLLKRLLGLLPTLLIVSVLVFLFVHLLPGDPARLAAGQDADAQTVALVRTELGLDRPLPQQFVRYFVNLARGDLGTS
IRTRRPVSTEIGERFLPTLLLTLTSMAWAVAFGLIIGIVSAVYRNEWPDRVGMTLAISGISFPAFALGILLMQIFSVELG
WLPTVGADTWRHYVLPSLTLGAAVAAVMARFTRAAFVEVIGEDFVRTARAKGLKERVVIAKHCLRNALIPVVTMMGLQFG
FLLGGSIVVEAVFNWPGMGRLLVDAVNQRDYPVIQALVLLFSLEFILINLVVDVLYGLINPTIRYR

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=306, Percent_Identity=73.5294117647059, Blast_Score=469, Evalue=1e-133,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=41.1242603550296, Blast_Score=255, Evalue=2e-69,
Organism=Escherichia coli, GI1789888, Length=309, Percent_Identity=37.8640776699029, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI1787761, Length=330, Percent_Identity=40.3030303030303, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1787497, Length=308, Percent_Identity=35.3896103896104, Blast_Score=187, Evalue=8e-49,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=30.8823529411765, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788504, Length=363, Percent_Identity=25.6198347107438, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33684; Mature: 33684

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTFLLKRLLGLLPTLLIVSVLVFLFVHLLPGDPARLAAGQDADAQTVALVRTELGLDRP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCC
LPQQFVRYFVNLARGDLGTSIRTRRPVSTEIGERFLPTLLLTLTSMAWAVAFGLIIGIVS
CHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVYRNEWPDRVGMTLAISGISFPAFALGILLMQIFSVELGWLPTVGADTWRHYVLPSLTL
HHHHCCCCCHHCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
GAAVAAVMARFTRAAFVEVIGEDFVRTARAKGLKERVVIAKHCLRNALIPVVTMMGLQFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGGSIVVEAVFNWPGMGRLLVDAVNQRDYPVIQALVLLFSLEFILINLVVDVLYGLIN
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTIRYR
CCCCCC
>Mature Secondary Structure
MLTFLLKRLLGLLPTLLIVSVLVFLFVHLLPGDPARLAAGQDADAQTVALVRTELGLDRP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCC
LPQQFVRYFVNLARGDLGTSIRTRRPVSTEIGERFLPTLLLTLTSMAWAVAFGLIIGIVS
CHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVYRNEWPDRVGMTLAISGISFPAFALGILLMQIFSVELGWLPTVGADTWRHYVLPSLTL
HHHHCCCCCHHCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
GAAVAAVMARFTRAAFVEVIGEDFVRTARAKGLKERVVIAKHCLRNALIPVVTMMGLQFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGGSIVVEAVFNWPGMGRLLVDAVNQRDYPVIQALVLLFSLEFILINLVVDVLYGLIN
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTIRYR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA